CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
CYP3A5	1577	Cytochrome P450, family 3, subfamily A, polypeptide 5	7	CP35; PCN3; CYPIIIA5; P450PCN3

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
23584898	2013	Cell line : HT 29 Source : ATCC Sample Type : - No. of Sample : - Stage : -	Meta-analysis	Polymorhpism	-	Meta-analysis provides evidence that CYP3A53 polymorphism may play an important role in the development of acute and chronic leukemia and colorectal cancer, especially among Asian and Caucasian populations. CYP3A53 (rs776746 A>G) polymorphism may play a role in the etiology of carcinogenesis and affect an individual's susceptibility to cancer in humans.
22930170	2012	Cell line : - Source : Aberdeen colorectal tumor bank. Sample Type : CRC tumor and Normal tissue No. of Sample : 264 CRC patients Stage : -	Microarray analysis,Real time RT-PCR and Flow cytometry	Up-regulation	-	Gene differentially expressed and analysed bye by Microarray. KM12C, KM12SM (SM),
15897573	2005	Cell line : KM12C, KM12SM , HT 29 Source : - Sample Type : - No. of Sample : - Stage : -	Tissue microarray, Immunohistochemistry	Up-regulation	-	In primary colorectal cancer, several P450s (CYP1B1, CYP2S1, CYP2U1, CYP3A5, and CYP51) were present at a significantly higher level of intensity compared with normal colon.

Gene Details

Chromosome: 7; NC_000007.13 (99245813..99277621, complement)
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Gene Type	protein coding
Gene Family	Cytochrome P450s
Description	This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2010]
Chromosome	7
Location	7q21.1
Start	99648189
End	99680026
Strand	-
Gene Sequence	>gi\|568815591:c99680026-99648189 Homo sapiens chromosome 7, GRCh38.p2 Primary Assembly ATAAATCTTTCAGCAGCTTGGCTGAAGACTGCTGTGCAGGGCAGGGAAGCTCCAGGCAAACAGCCCAGCA AACAGCAGCACTCAGCTAAAAGGAAGACTCACAGAACACAGTTGAAGAAGGAAAGTGGCGATGGACCTCA TCCCAAATTTGGCGGTGGAAACCTGGCTTCTCCTGGCTGTCAGCCTGGTGCTCCTCTATCTGTGAGTAAC TGTCCAAACTCCTCTCTTTGTTTCCTTGGACTTGGGGTGCTAATCGGGCCCCTTTTCCCTTATCTGTTTT GAAGATCAAAAGAGATGTTCAAGGAGAAGTAGCTGAAGTGTTGGACGCTACAAACGCATAGAAGTTATTA TTATCTTATGCAGATCTATGAATGAATAAATAAGCATTTCTCCCATCCACCTTCTAATTTTGGTGACTAG GAGGGTTTAGGGACAGCATTTGGTAGTGGGAATGATTTGATTAGCTTAGATCTGACGAAGACTAATCAAT GAAAACATGGCAGCGGCAGATTACAAACTGCTGATCATGATGGACAGTGTGATCCTCATCCCCTTCCCAG GCTCTGGGGATTCTGGGTACAGGAAGGAGTGGCTTGCATTTTTGTCTCATTAATTCGCTTTCTGGGTTCT GTGTCTGCTGGAAGGGATGTGTAGCTGTATTGCCCCTGTAGACCTGGTTCCTGCTCCCCCGCCTTCCAAC CCAGGATATCATTTACATAACGCACCAGGGGACACCAAGACTTCATGGGAAGCTGTCCCCTGGCTCTTCC CTCTTTCCTGTGCCATGCCCCTGAAAATCCCCTCCCTCCTATGAGTCACTCCTCCACCCTGTCATACACA GGATGGTTTATCTTGCAATGATTAACCTCTAGAGCAAAGGAGACCTGGAGGAAGTTTCGAGGATTTATTC TTTGCTTTAATCTTTTTCCTCCCGTCTCTGGGAGGCTAGGATTAATATAGAGCTTTGTTTCTCACCTAAT GGGAATCTACTAGCAGCCTGAAAAGGCAGGAGCCATGAAAGCCAATTTGGATTTTACATATTTTTCCCCT TTATGTTACAGTACAGGAGGGCAAACCCTCTCACTGGTGGGATTCCTGGCATCCTAGAGCAGGTGGAGAG AAGAGTTACTTTCCACTGTGGGTAGTGGAGGCTCCACCTGTCCCATTAACTTCTACCTCAATTTGACTTT TATTAAGAGCAGGGAACCACAATGACATGAAAATAGACACTATAAACCTCATTTTAATTCTTTCACAGAA AGCTTAGGAATTCAGTGAGTTGTGGCAACATGGTTTCCATTGTCTAACATTTTTAAATGAATTGATATGG TTTAAATTCATTCATTTTTAAACCAGAATTTTTTGGAGATAGACTATTTCCAGCATGTTCCTTCTGGATG GTAAAACAGGGCTGTTAGTTCAGTATTTGTGACAATAAGTGTGTGTAAAATAATGTCACCTTTCCTGAAT GTCAGGAATATGAGTCTAATGCACAAATGTATACCTCTAAGACAAGACTGCACGTCTTTTCAAATATACC TGTCCGGCCATTTATTTTAATAACTCCTTTTCGAATATACCTGCTTAGCAGATTGTCTTAAACTCTCAGG ACAGGGGAGTAAGCAAGACTGTGAGCCAGTGACGATAGCAAAGGCTTCCAGGTAGGATCCATATGAAGTG AGAAAATATTCCTCAGCTCTCAGGGTAGAACTCCAAAGAGATATTCATGGGTCCTGGCCCCACCGTGGAG GTCACTCAAAGGGCAAACAGGTTGGCATCTCATCTGCTTCAAGCCTGGACACAGGGGCACCATCTGTGTC ACTCTGTGTGTGGTCTGCCATGTTGTGGGCCGGTCACTACAGACTCGGGCAGCCAGGCAGACAATGCCTT AGCCTTAGACAATGCTGGTGCAGCCCAGGAGTCAGAAAATGCAGTGTAGACCAGGCCCTCCTTAGGCCAA CACAATTACATGCAATAGATGACTGGCTTTTCTGTTAGTCTCTTCACTGGACCCAAAGGCTGCATTACTC TACCAGAGGGGAGCTGGAAAGAAACTAAAGAGTTCGCCCAGCACAGCATCTGCCTTGACATGGTACCATG TGAATCTAGACACTCACCAAGATCTTTCCTTGGGGGCCAATGCTGCTGACACATTAACTCAATAGCTTGT CCTCACCTGAGAGGTCAGGTAATGTGTTTAAAGTTCAGGAGCAGAGATTAGTGTCATTGATTTGACATGG CTGTGACAACAAAGGAGGGAACTGAAGTGGGAATACCCAAGGCCACCCTGGCTTTGGCAGGTGGTGCACG CACTTCCACTAACTGTTCTGGGGCAGGGAACCAAATGTATGACTGGGCCTGCTCATGCTGCCCCTGCTGA GTCCTCCAAACCCTGCCCTTCATGTAATTTCTCAGTTTTATTTTATCACATTTTATAAGTCACTGGATGT TTACAAAATGTTTGGAACCTATACTGCCTTGAAGGCTAACCTCTAAAGAGGAGTAAACAAGGTCTTAATA CAACTCTCCGGGACGTTTTATCATTACTTATCTTATATGCCATACTGCACCATTTGCTATCAACAGGAAA GTACCTGGACTTTGGAAGGTCCCTCTGTGTCTTTTAGCTGAAAGTACATATGAGGCATGTGGATTCTTTT ATGCACATCATCTTTTTCAGCCACATTTTTGTAGTTTGCCTCTCTGGAGCCAACTGTGTGGGGCTAGCAG CTTCACAGCTGAATCAGTGTCTGGCAACCTCTTCCTTCAGCCTCTCTTCTTCCTCCAGTTTTCCATCCCT CAGTCACACCGGAGGGGGAAGGTCTGCAAGGATCCAGAACCATCAGTTGGAGGAGTTTGCACATGACTCA TGAAAGATGAGTTCCAGGCAGGCCTGCCATAGTGAACACCAGGCTTAATGGGTTTTTCCTCAGAGATACT TCACGTACAGAGGCAGTGAACTGACTGCTTTCTGGTTGACCACCTTGAAAAAGATGAGTGTGCCTGGCAC TGTGCTTCTCAGGTGAGTATGACCTGAGAAGTATTAGTTGCTGGTTCTTCTGCACACAATCATTCAAGGA CATATGGATCAACCATCCTCCTCAACAGCTCAAATCAACCAGATCATCTGACCACAGAGACTGAGGTGTA CCTGAAAGCTGCCCACATTTCTATAAGGCCAATAGAAGCCATGAACACAGTTGTCAATCTGTAGAAATAA GGACTCCATGACTCCTCCAAGGCCTCTCTGTGAATGAACGTTTAAGAAGGGCTAGATCCTAAAACAGGGT CAGAGCTTAGAGGGAAGAAAAAGCATAAACATTTCTGAGCAAATTGTAAGGGCAGTGTCACCATAGGCTC CCAGTGACCCTCTGTGATTGAGTGCATACAGTGATGCAAAATCTCATCATCAGTGCAAAAGACAAAAAAA ATCTTACTCTTTCTACCTAGGATGAGAGTCCCCAAATCAGCGAAGAGTCCACTTACTAAACAGACATAAG GAAATGAAGTGTCCTGGAAGAATTCCTGCCTGAACCTCTCAGGAGCATTTGAGGACATTTATCAAGTATT CACTCCAGGATTGGGACTATGAAGACTTCAGCTGCTTTCAGCTAATCATTGAGACTTTTCAGGGGTCTCA GAATAGTCAGGAAAGGACCTGATGAGTGAATGCAATTACTGATGTTGGAGTTGCTGTTATTATTTATCGT GTACATATTACCTCCCTCTCTTGACCATTCCAGTTCCTGAGTAACTCACCAGCCCTCTGATCTATAAAGT CACAATCCCTGTGACCTGATTTCTGTTTCACTTTGTAGATATGGGACCCGTACACATGGACTTTTTAAGA GACTGGGAATTCCAGGGCCCACACCTCTGCCTTTGTTGGGAAATGTTTTGTCCTATCGTCAGGTGAGTTG CTTGAGCTTCCTCTTTTGCTTCTTATGGTTGCAAACATCAGCTTAGTTCCATCAGTAAAAATGCCCCTCC TTGGGAGGGAGTTCTGAGGTTTCACATTTTCAGAAATGGTGGGACTGGGTGCAGTGGATCATGCCTGTAA TCTCAGCCTCTGTGAGGCCAAGACTGGCAAATTGCTTGAGCCCAGGAGTTTGAGAACAGCCTGGGCAACA CAGTGAGACACCTGTCTCTAGAAAGAAAAAATTACCTGTGCATGATATGGTAGCCCATGCCTGTAGTCCC AGCTACTCTGAATGTTAAGGTGGGAGGATTGTATGAACCCAGGAAGTCAAGGCTGTATTGAGCTGTGATC GCACCACTGCACTCCAGCTTGGTCAACAGAACAAGACAGAAAGGAAGAAAGAAAGAGAGAGAGAGAAAGA AAGAGAGAGGAAGGAGAGGGGAGGGGAGGGGAGGGGAGGGGGGAGGAGAGGAGAGGAGAGAAAAGGAGAG GAGAGAGGAGAGGAGAGGAAAAGGTGTGTAGGCTCCACCCAAAGCATGGCCAGGTTTACCCCTGGAGGGA AAGTCACAAGCTCATGTCCAGAAGGCCAGTAGCAGCAAGCTGCTCTCCAGCCCAGATTTCCTATCCTGTG TACCTGGAGCTTGTTTCTCAGATTCTAACTCTCACAACTGAAGCCTCTGTTGTCTGATTACTATCTGAGA ATTCTACACAATTTTACCCTCGATAAAAGCAGTAATTTCTTCTTCATCTTTCCCAGATCAACTCTTGTAG TAGATCAACATTTCTGGGACCTTCTTTTGCATGGTTAAAACATCACAGCTGAATCTTAGCAACAGGAAGG TTTGTTTTTATGTTTCAGAAGTGAAAGCTCAGAGCACGCATTGTAATTTGCTGGGTGTGATGTGTAGAGG TGGCATTTCTCCATCTTTTCTGTGTTAAGCTAGAAAACTGGAAAGGAAGTCTACTTTCTCATTCACTCAC TCACTTTCTCACTCAACAACATGCCTTAGACTTATCTAAATCTGCAAGACTAAAAGAGGTTCCTGGTTTC TTTAACTTTCTAATTCTGCTAGAGTTCTAGAGAGAGCACATGAGATAAATGAAAAGGATACTGATGGAGG AGATTAAAAAATTGTGCATTCCCTGCAGACACTCACTTTTCCTCACCTCAGTTTCACCCCTGCCCTTGCA GGTGATCATTCACGGGGTTAGGAGACTTTAGAGAGAATAAAAGAAAAAGCAAAAATACATCAGAAAGACA AGGAATTACTTACTGGTCATAGACAAGGGTGAGTCCTTCAGTACTTAGAGAAAATTCAAGAGTGACTTTA AATTCCCCACTTCAAATATATTCTCTGTTTTCTTGTCTTTCCCTTAAGACATCTCTGAATAGCTTCCTTC AACTGCCAGTGAAAGATAGCAGGCCTGATTTCATTGGACGCAACTGTTTTCAGCCCCAATTAGAGGTAGG GTTTATTCTATTTAAAATAATAATCAACTTGTATTTTGTTTCCTCTCCCAGGGTCTCTGGAAATTTGACA CAGAGTGCTATAAAAAGTATGGAAAAATGTGGGGGTGAGTATTCTGAAAACCTCCATTGGATAGACCTGC TACTGTGAGGAGGTTACCCCACTGCAGGATAGTCTCTGCCCAGGTCTTCATGGGATGAAGCTCTTGTCAA CCTAAATACAAACAGAGAGAGGTTCTCTGAAAGAAGAGGATAATTACTTGGGAGTAGAATATTGCAATGG GAATCTGCTTGCCGTTATAAACTATGTGCAAATTCAGGGAGGTAAACAAGACAAAGATGCTCCATAGAAA ATATGAGAAGAATCTCATAACTGTTTTGAGATAATTATTGTTAGCTACAAAGATCAATAACAAGGGTGAT GCCACACCAAGGTTGGACAGGCAGTTGCTGGACAGGTGTCCTTGCAGAAATATTTTTGTGTAAAGTTGAA ATAGCCTTTGTGCAAAGTTGTGGTTTTTGTAGACACTTTTGTAATAGTTTTGTTTCCAGGAACACAAGCA TAAGAATCCTCTCTTCATAGCCTTCTTGGGATTTATTTGTCAGGGTTAAAAAACAATTAGTGACATCACT TTGGTTCTGATAAAGTTCACACTCGCTATTGTAAAACTTTTCGAGGCTTGTCCTACCAAGGATCCCATGT GTCACCAGGTATCGAGGTCTTCAGTCTGAACTAGGCTAGGAGCATTGTGGTTACCACTTTTCTGCAGGTT TTGGTGGCCCAGGGACTCCCAGCATCGCCTTCTGTCCAGTGTCTGCCTATTCCCCTCTTCTTTTTTTCTT CCTTAGGTGCCCTTTTATCACATGCATTGTCTCAGACCCTTCTAATATGTGCTCATAAATGCATGGCATC ATCTCCTTCCCACATTGATTCACTTTCAATTAAAAGCCAAAACTCCTTCATTTAGACTGAATTTAACATG TGCTTTTGAAAGAAGGGTTGAGAGATAATAGAGAAACAGATTGGGAAACCACTTATGCTCCACTTTTTTA AACTTTCTCTGCAAGTATGGAATTTTTTGTTCTGCTTTGTTGTTTAAATTTAAGCCAAAACTTCTTAATA GAAGGATATACAAATATTTATTGGTTTATACCATTGCACTTACTTTGAAGAAGAGATGCTGAATATTATT AAACCATTGTGTTCCCTGGTGGGCTGATGGACTGTGATTTTATAAGGTGGTCTCAGCCAATTGCAGCAGC TGTTCCCTGTCAGAGGGGCTAGAGGTTTGGTGAGAGCAGTGGATGAGGTGCAGTGGTGTGTTTGTTCACT AGAAGCAAGTGGGAGAAAGCTTTGCCTCTTTGTACTTCTTCATCTTCTCCCCTCAAGTCCTCAGAATCCA CAGCGCTGACTGTGGAGTGCTGTGGAGCTGGCATGGCCCATACAGGCAACATGACTTAGTAGACAGATGA CACAGCTCTAGATGTCCATGGGCCCCACACCAACTGCCCTTGCAGCATTTAGTCCTTGTGAGCACTTGAT GATTTACCTGCCTTCAATTTTTCACTGACCTAATATTCTTTTTGATAATGAAGTATTTTAAACATATAAA ACATTATGGAGAGTGGCATAGGAGATACCCACGTATGTACCACCCAGCTTAACGAATGCTCTACTGTCAT TTCTAACCATAATCTCTTTAAAGAGCTCTTTTGTCTTTCAATATCTCTTCCCTGTTTGGACCACATTACC CTTCATCATATGAAGCCTTGGGTGGCTCCTGTGTGAGACTCTTGCTGTGTGTCACACCCTAATGAACTAG AACCTAAGGTTGCTGTGTGTCGTACAACTAGGGGTATGGATTACATAACATAATGATCAAAGTCTGGCTT CCTGGGTGTGGCTCCAGCTGCAGAATCGGGCTAGTGAAGTTTAATCAGCTCCGTTGTCCCCACACAGAAC GTATGAAGGTCAACTCCCTGTGCTGGCCATCACAGATCCCGACGTGATCAGAACAGTGCTAGTGAAAGAA TGTTATTCTGTCTTCACAAATCGAAGGGTAAGCATCCATTTTTTGAAATTTAAATAATGATTGATCCACT GATTAAATTTTTATTTTGAAAAAAACATATATTCACAGAAGGTTACCTAAAAAATGTACAGGAAGGTTCC ATGTACTCTTCATCCTGTCCCGCCCAGTGGTAACATCTTGCAATCTTGTATATTGCAATATATATCTAGT ATATTCATATTATCAGGTTGGCACAAAAGTTAAAATGGCAAACTACAGGCTGGGCATAATGGCTCATGCC TGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGTTCGAGATCAGCCTGACC AACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGCGTGTGGTGGCATGCGCCTGTAGTC CCAGCTACTCAGTAGTCTGAGACAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGA TCACGCCATTATACTCCAGTCTGGGCAACCCAATGAGACTCCATCTCAAACAACAACAACAACAACAACA ACAAAAACCGGCAAACTGCAATAACTTTTGCACCAACCTAATACTATAGTACAGGAAATTGACTTTGATA TAGTTTACAGAGCTTTTCAGATTTCACCAGTTTTACATGCCCTTGTTTGTGTGTGTTTATGTGTGTGGGT AGTTCTAAGCAATTTTTCACATTCGTAGATTTGTGCAACGACCAGCACCATCAAGATGCAGACCCATTCC GTCACCATGTGGCTCCCTCCTGCTGTCCTACAGTCACAACATGGAGTTTGTCTTTTTCTCTGACAGGTTC TATATCAGAGCAAACTTTTATTTATTTGAGGAGGCCAATGTATTAATATTTCCTTTTATGGATTGTTCTT TTGGTGTTAAGTCTGAAAATCCTTTGCTTAGCCCTCCTTCCTACATTGCTTTTTCTAAGAGTTATATAGT TTAACACTTTACAAAATGTAACTCTATTACCCATTTTGTGTTAATATTTGCATAAGTTATGAGATTTAGA TCAAGGTTCATTTTCTGTGGACTATGGCTGTCCAAATGTTCCAACACCATTTTGGAAAGGTAGGCATATT GTCAAAACTCAGCTGAGTATATTTTGTGAATCTATTTCTTATTGTTTACTCCTCCACTAATACCACACTG TGGTGACTCTAGTAGCTGTACAGTAACTCTTAACATCATATAGGGCAATTCTTTCCACTTTATTGATTTA TATTTTCAGAATGGCTTTAGCTTTTCTTGTCCCTTGCCTTTCCATAAAAATTCAGAATAAGCTTGTAAGT GTCTACAAACAAACCTGCCATAATTTTGATAAGAATTAAAGCAGAGGTGTCCAATCTTTTGGCTTCCCTG GGCCACAGTGGAAGAAGAAGTGTCGTGGGCCACACATAAAATACACACACACACACACACACACACACAC ACACACACACACACACACAAATGGTCTGTGTATAGTTTTCATTATATATCTACCACCACAGATAAGCAAA AATGTCCTTGCATAATAATCCTAATTATGCACTGCCCCATTCAGAGGGTCTTTCAAAATCATTGAACAGG TTCCAAGTTTGCAATCACTGATACAGAAAATGTACATATCTAGCTAAACTTCACTACTTTTTTGATATTT TTTATTATAAAAGAAAAGAGAACAACATAAAACTAGTGGGGTACTTGACATTGTTTTTGAGAAACTAATC CATCAGTATCTGGCTTGATGGAAGTAGTTGCAATTCTCAGTGAGTTCTCAAGGTGCTCATCAGATATTTT GGTTCTAATTTTACTCTTCGTGTTCTTCATCCTTGAAAATAGTAGCTCACAAATGTAAGTGCTGCCAAAA AGCAATGACATGAACAAGGTGTGATTGTGAAGCAAGGGATATTTGTCATTGGGAAGACAGGTCTTACAAA AGTCCAGTAAAGAGGCAAAATCAAATTTTTCTATAAGTTGAACATCAGATTGCAGCTCTAGGCATTCCAT TTCAAAATTGCCAGGTAACATATATATGTCGACTGAAAATGGAGTTGCAAATATACCAAAATATTGATGA TTTTTTCAGAAATCTTGAAATACCTGTTTTCAAATTCCTGTATCAAATTGAAAAGCAAGGCTGCGTATTT TTGGCTGTTCACAGGACCATGTTTAGCCAACATGTCGAAATGCATAAAATTGTTTGCCTTAATTTGAGCT TGCCATAATTTCAGTTTCATATGGAATGCTGTTATGGTTTGAAACATTGTATTGTTAAGTTGGTTTTCAA CTTGAAGACACAGGTTTAACTCACTTAAATGGGCCGTCAAACCCACTAAAAATGCTAAATCTGTAAGCCA GTTTTCATTGTCAAGTTCTGGCACCAATTTTGTTTGATACCATAAACAGCTTGATTTCACATCACAAAGC ATAAAATCTTTACATTTTGCCTTGACTTAACCATCTTACTTCTAAAAAGTGAATGACTTGCTAGAGTCAG CATCCATACTTTTAAGGAATTCCTGAAACTAGCGATGATTCAATTCCTGGGCCCTTGTGAAATTTACAGC CTTGATGACAATTTGCATGACGTTATCTACTTTTAAAGCTTGTGCACATGGATTTTCTTGATGTATTATG CAATAATACTTCATCAAATGTGAGTTTTGTGTGGCAACTGCATCATCTATTAATTGTACAAGTCCCTCTC TTTTACCTACCATCGCCAGGGCAGCATCTGTAGCTATATCACATATGTTTACAAAGGACAAAGAAAATTG CTTTAACATATTTTTCACTGCTTCATATAAATCTCTTGATTTAGTTGTGTCTTTTAATAGCATGGTGACA TTTCGATTTCTTCAGTGACATTATATTCATCATCAATACCTCTAATAAAAATAGCAAGTTGTGCCGTATC TGTAGTGTCAGTGCCTTCATCCATCACCAAAGCATAAAATTTTAAATTAGCAGTTTTACTCTCCAAACGT CTTTCAATAGATTTCCCAATTTCTCCAATTCTCCTGGCTATAGTCTGGTGAGACAAACTGATTTTAGAAA TATCAGTTTCTCAAGGCAAATAATATCTACCACATCTTCCAGACATTGCTTAATAAACTCACCATCAGTA AATGGTTTTGATTTTTTTGCTATTAAATTTGCTACCACATAACTAGGTTTTACCTTACGATTGAGTCCGA GTTGTAACTTTTTAAAAAATCTTTTTTGTTGAAAAGACAGACTTTTTTTCAGTTCTGCTATTTTGTCCTT ACAACACATACACACCAAATTTGTCAGCACGTTTTTGCATATAATGCCTCTTCAAATTGTAGTCTTTGAA AACTGGCACAAATTCCGTGGAAATTAAGCAGAGTGCTTCGCTATTTGCCTCAACAAGAAAAAGTCATTTG TCCACTTTTCATTGAACAATCTTCCTTCATCCATAATTTTTGTTTTTTAGGGTTTTCTTTTTAAGACATT GTGGAAGCCATTCTGGAATTAAAAGCATTATAATAGATAAGCAACTATATTTACTTTTATTATGGAAATT AACAGATAGGAAAATAGAACAGAAAGCAAGGTTTAATAATCAAATAAGAATACTTACATGTCTTCTAAAT AATATTAAACACCTATCATCTACAAAGGTAGGTTGAAATATTATTGATAATTGCTGGGTTTTACTTGCCA AATTGCCACAAACACACCTAATACCTGACAGTGTCAATTCAACTGTCCGTGATTAGAAGATAACACACTG GAAGTCGCACACCACCATAAAACTGAAGCCACACATGCGTACAAATGGCGACAGTGTCTGGTGTACAGCA GCGCTCTGCCTTGTCCAGAATACACACTTGAATTCTTTGTCACAATTCACTTCACGTGGCACTGCAATAG CGTCCTCTCGCTCTTTGTTAGTTAATTTTAATGGCTTTTAATTTCTTCTTGCTGAACTGTTTGCAATTAT AATGCAAATTATGGATACTAGTCCATTATTTGTGGATGTGACATACTCTGATTACCCCTTTCCATTCCAT TGTTGTCTACGAAGTTCACACTTGAGAATCACATAGTCAAATTACAAAATTACAAAAAAAATTGCAAAAA AACTCAAAATGTTTTAAGAAAGTTTCCACATTTGTATTGGGATACATTCAAAGCCATCCTGGACTGCATG AGGCCTGCAGGCCACAAGTTGGACAAGCTTGAATTAAACCAATAGAACAATTTGGGTATAATCTATATCT TTACTATGTTCAGCCTTTCATCCCGTGAATATAGTATGCCTCTCCATTTCTTTAGCTTTTATTACTTTCC TCAACATTTTATAGTTTTCAGCATAGAGGTCCTGTACATCTTTTGTTAGATTTACACCAGAAATATTTCA TTTTTGTTGGAGTAACTGTAAATGATACTGTTTTTCTTGTATTTTCAGATATTGATTATTGTTACATAGA AATGTGAATAATTTTGTTTGTTGATCTTGTATCCTATAGCCTTGCAGAACTTACCTATTCGTTCTAGAAA TTTTTTTGTATATTCCTTGACATTTTATACATTGACAATTATGTCACCTGAAAATAGAGACAATTCTATT ATTTCCTTTCCAATCTGTATGCCTTTTATTTCTTTTTCTTGTCTAGTGTATTAAGACATCAGGTATGCTC TTTAGTAAGAATGTTGAGAGTGGGCATTTTTTAGTTCTTCTTGATCTTGGAAAAACCATTCAGTCCTTCA TCATTAAATGTGATTTAACTGAATGATTTTTTTACAGATTGTCTTTATCAAATGAAGGAACTGTCTCTCT CTTCCTAGTTTATTGAGATTTTATCATGACAGCTGGAAGTACACATTTTAAAACAAAACATAGTTGTGGA AGATAAGAGAAAGTTCCAAGCATGCTGGCTTGATAGTCCAGCCCCAAGTTGGGAAAAGTAATTATCCCTT TCTTTTTCCTTCTATTTATGGAATAAAAAATTAAGAGAAAAGAATTTTCAAGGAAATTGCATTATTCCTT CAAAACAGGTTTCTAGTCTTTAAGTATTACCTACTTTTCAAAAAAAAATCACCACATCATGGCATCCCTT TTTCAAGTTGCCCATGCTGTAGGTGTATTAAAGACAGAGCTGGTCTGAGGCAACATACAGTCTGCCCATC TGTCACCAATCCTTTTCTACTCTGCACACTCCTGGGGAAGGGCTAGGTCTTGTTCCTGTCTATTCCACTG GAAGAACAGTTCCCTACCACGTGGAGCATTTGCAATTAAAAGGAGACTGAGATATAGAGGCAGGAGACCA CACCAGATGGCTGGGTCTCCCCACTCCCACCCCCGCCCCACATACACTCAGAAGAGGCTAGGCATCTAGG ATCTCCATTGAGCATCTTGAATATGGCTTGCCATAATATCATATACAGTCAATAAATATTTGTTAAATAA GGATGCCTCTTCAATATATTTTGTGCAACCATGAAGATCACCACAACTAATGTGAGAAAAAATGTTTCTG TTGAACTCTAGTCTTTAGGCCCAGTGGGATTTATGAAAAGTGCCATCTCTTTAGCTGAGGATGAAGAATG GAAGAGAATACGGTCATTGCTGTCTCCAACCTTCACCAGCGGAAAACTCAAGGAGGTATGAAAATAAGAT GAGTCTTAATTAGAAATGTAAAGAATGAATCTGGGGACAGGTAGAAAGTAAGATCACAGTCCGTTTCCAA GGGGTAGTCCACTGAGTTCGAGCTTCCTAAAAATGGTCTTTTATCTTTATGTACAGAAAAGACATCACAA AATTCATTACAAAATGTCACTTACTGCTCCATGCTGGAGAAAGCCATATCCTTCTGGGACTTGAGTCTGC ACATTTAACTACAGGTACTGATCTGTTTTGTGCTTAGATGTTCCCCATCATTGCCCAGTATGGAGATGTA TTGGTGAGAAACTTGAGGCGGGAAGCAGAGAAAGGCAAGCCTGTCACCTTGAAAGAGTAAGTAGGAGCAC AGCCATGGGGTTCTGAGCTGTCATGAGCCCTTCCAGCTGCCTGCCATGGAGTCGACAGTCGCACTGTTGG GTTACTCCAGTGACCAGACAAAAGCAGGGCAGCGCTGCAACTCCAAAGAGCCACCTAAGAGGGAGTGGCT CCCATGAGGCGGCAAGTCAGCAAGGGAAAAGGGCCTTCTCTCCTGTGCACAGGAGCCAGGATTTACTTAT CTGTTAACTTGTCACCATAAATATTCTGGGAGATTAAATACATACTTTAGAAATTAAAAAAACATGATTG TATCAAAGTTTTGAGTGTAGTGGATATGGAACTGTGGGTAAGCAAGCATTTGGTACTTGTTGCCTTGCAT TGGGTAAGATGGGAAAGTTACAATGGGGAACTTGGAACAATTTCAATCCCTTCATGGTTTTTCTGAGAAT ATCAGCAAACTATGAACTATTAAACCTTCCCACTACTTCCTTTTCCTCCAATCTCAAAAAAGAAAGGGTG CTAGAAATGCTATGTGTAGAGCAAGCCTATTATTTGCTGTCTACAATGGTATGTGCTTCAATTATGCAGG AACGACAGGTGTAATCTGAGCCTGTCCTGTTCAGACTTGGGACATGTGGTCACTCAGTTTTGGGTTCTCC AAATCAATGTTGGAGAGATCTATTTTTTTTAACCAGAACATTCTTGATTGTCACATCTTACAAAAATGAC TCTGCTCTCAGCGCAACTTCAGGTCAGAGGAGCTGGGGATAGTGGGGTTTTCCAGAGCATTAGCAGGGAG TGTAGAGAATAAAGGATGATATTTCTAGGAACTCAGAACAGGGTGTTACTGTTTTGTAAAGTGTTGAAGA GGAATTGGCTCTGGGCATAGAGTCTGTAGTCAGACAACGCCACCTTTCTTGAATCCACTAGGAAGAGTTA ATTATTCTACTCTTGTTCTGCTGAAGCACAGAGCTTACATATCTTATATCATCCACACTCAACACATGCT ACTGTAGTTGTCTGATAATGGGTCTCTGTCTTCCTATGACTGGGCTCCTTGACCTCAGAGGTGAGTCTAA CTCAGCTTGGTGTCTCCATCACCCCCAGCATAGGGCCAGCTCCATCACTGGCACCAGATAACCACCTTCT GAGGGAGTAGATGGAAGATGATTCAGCAGATAGTTCTGAAAGTCTGTGGCTCTTTATGTGTCTTGACTGG ATATGTGGGTTTCTTGCTGCATGTATAGTGGAAGGACGGTAAGAGGTGCTGATTTTAATTTTCCATATCT TTCTCCACTCAGCATCTTTGGGGCCTACAGCATGGATGTGATTACTGGCACATCATTTGGAGTGAACATC GACTCTCTCAACAATCCACAAGACCCCTTTGTGGAGAGCACTAAGAAGTTCCTAAAATTTGGTTTCTTAG ATCCATTATTTCTCTCAATAAGTATGTGGGCTATTATTTCTTTCTCTCTTTTTAAAAATAACTGCTTTCT TGACATATAATTCACATATCGTATAATTCATCCACTTAAAAGGTACAATTCCATTGTTTTTAAGATAATC AAAAATATGTATGACCATTACTATTGTAAACTAAAATGTTTTTGTCAATCTAGAGCCCTCACACACTTTA GCTGTCAACACCCCACCACAAACCCCACTGCCCTAAGCATCCAATAATCAACTTTCTGCCTCTATAGATT TGCCTATTCTGGACACTTCATAGAAATAATATCATTGATTTTTCTCTGTTGTTTTTTATTCTCTATTTCA TGAGTTTATTTTAGTCTGTTATTTTCTTTCTTTTGCTGGCTTTAGGTTTCATTTGCTCTTCTTCTTTTAG TGTTTTGTGGTGTAAATAATTATAATCAATTTGAGATATTTTCTTCTTTTAAATTTAGATATTACAGCTA TAAATTTCCCTCTGAGCACTGGTTTGGCTACATCCTGTGTTTTGGTACATCATGCCTTCTTTTTGTTCAT CTCAAAACAATTTCTTGTTGCCCTTTTGATTTCTGCTTTGACTCACTGGTCACTTAAAACTGTATTGTTT AACTTCCACAAATGTATGAGTTTCCCAAATTTCTTTCCCTTATTGATTTCTAGTTTTATTCCATGGAAGT TGATGTACATATGCTGTGTTAATTCTATCTTGACTATCATTTCCTGAACAGCATGATTAAGTTAAGCAGC AGATTATGGTCTACATTAATCCAAAAACTCTAGTCCAATAGATAAAGGCTAAGAGGTCAGGGAATTTAAT TCTATTACTTTGGTCACTCCAAAGACTCAGAAGGTGCCATTGATCTCACTGCTGTAGTGGTGTTTCCTAT GTATAGACCTGCCCTTGCTCAGTCGCCGGCCTGAAAGAAGGGCAAACATGATAAAAGGAATGGGTTCCAG TTGAGAATCATGATGTTCTTATTCTTATTACTGGTAGAGAAAATTATAATTGCTCCAGGTAAAGTTTGCA TTTTCAATGATTTCCTTTTGTTTGTTTTGTTTTTCCCACAGTACTCTTTCCATTCCTTACCCCAGTTTTT GAAGCATTAAATGTCTCTCTGTTTCCAAAAGATACCATAAATTTTTTAAGTAAATCTGTAAACAGAATGA AGAAAAGTCGCCTCAACGACAAACAAAAGGTAAAATCTGATGGTGGTTAAATGACGATGTTTAGGTTTTG ATAAATTTAGATTTTATACACATGATAGAGCATGTATCTGTATTTTTAAAAATAAAGACAGAGAACTTAT GTTTAGAACAAGAGAAGCCATTTGGTAGAAATAAAGAAGGAGATTGGGGAAGGAGATGAGAATGAGTCAG AGAGATAGCATTTAAAACTTGAAATCAGGCACAACAATTAGTATGTCATGATATAAACAGTATTGAGATA AAATTTTACCACTTCTCTTCCCTTTAATAAATTGTCAAAGGATAAAGTTTCCTGTTTGAAAATATATTTT ACTGGTATTGTGCTTTCCTCATATCACAGATTGGTAAAGAATCATTTTAAGTCCAAGACTCTTATTTTAC ATATTCTGCAATTAAAGGTCCTATGAGGCTACCTGCCGACTGCTGACATGTAGTGTGTGGTAAATGTGAG TGTTTCACAGCCTGGAGTGAACAGGGGTCTTCTCTGAGAATTGAGGTTGCAAGGCTGGCTAACTCAGCTT TGCCTTCACGAGCCCTAGAGGCCAGCCGAAGGATGTCTGCAGGTCAGGGAGACAGGACCAGGTAACCCAG CTGTCACTGAAGATTATATAGAGTTTGAGAATGTTGGAATATTTGAAAATGCTCCCCCAAAAAAGCTGCT GATGAGTTCTGGAAATGTCAGGAGATTAATCTATACGGACACTGCTGAAGAAAAAGGTAGAAGAATAAAA GATCCAGTACTTCTTCCTGGGTAAGCAGTTATGACCAGAGATGGAACCGGCAACTCTTTGGCCAGAAAGC TGTATCCAAAAGACAGAGAAGATGAGAAACAGGGAGGGCAAAGGCGAAAAAGCAATTGGACATGATAGCT AGATTTGTTTCAGGAAAACATCCTGCTTTCCAAGGATTTAGATGAATGTTTTTGTTCACTGGTGACTCAG GTAACACGTCTTCAAGAAGCCATAGGGAGGTTGAGGGAGGGAAGTCAAGAAGGGAGGTTGAGGACTGCAC TTTTGATTTACTTCTGACTTCACGAGTCACTTTCTGCCAAAGAAATCTCTCCTTTTGCTTCTAGCACCGA CTAGATTTCCTTCAGCTGATGATTGACTCCCAGAATTCGAAAGAAACTGAGTCCCACAAAGGTAACCAAG GAGTGCTTCTGAGGGCTACTGGCGGGGACACTAAGAGGGAGGGCCTTGTTCTGAAAATGTGCAGGAAGTA TTCCAGGAAGATGAGAATTTTTGCCACATAGCAGAACAACACACATTTAGATGTTATAAATGGTAGCTGG AGGCACTTTCCAGAAGCCCACAGGTATAGCCATGTTCCAGGCTGAAAGGGCAACCCTAAGCAAACCTAGA ATGCTTGGAGGACAGTCAGTGGTTTGTGGATCACCTACATGAGATCAAATGCCAGTTCTCAGCCTCCTCC AGATCCACCAAGTGAGAACCTCTACTTGGAAATTTATATCAAACATACCGATCAGGAAGCACACTATCCC AGTAAGGGTGATTTTAACTGGCAGTACTTGAAAGTGTGTTCGCAAGGTTAATCTACTGCAAAGTTTTATT TTTCCCTTTGAAATGCATAAGTAACTAATGGGGGACACCTCTGATACCATGTAAATCTACTTCAATCTTC AGTCTTGTATCTACTAGTTTTATGACCCATGGATGGTTTTAACCAAAACCATTATTACTAAGACAGTGGC AAAATGATAACCATGGTCAATTTCAAGCTACCAAGATTTGGCAACCATCTCACAAAATTTTTGAATATTT AACAATTGGTTCTAGAGAGCAGGACTCAGCAGACTCCAGTATACCACTTTAAACATGTCCATGTCTACAT CTACTTCTGTCTGTCTATCTATCTGTCAATCATCTATCTGCCTATAATTTATCAATTAATCATCTATCTA TCTCAACAAAACTTGCTGTGATAAAGAAAATAGTCTATCATTTCACTGTTTCATATAGAAATCACTAGAC ACATATGGCTATTGAGTACTGGACATGTGGCCAATGCCACTGAAGAACAATTTTTAAGAGTATTTATTTT TAATTGAATAAAATTTGAATTTAAATAGCCACATGTGGATAGTGGCTACCAGATTGGACAGCAGAGCTCC CAACTTTAAAATTACAGTTCAATTTCAACTCAGTATAATGGGGTTCAATGTAACTGAGTAAAATAATTGG ATGGTTGAATTTACCCACAGCAGCATACAGAAATATTCACTGATAAATCAGAACTCTGTAGACCTTTCTC ACACTCATTTTATATTGTGTTTGGTTGTGAGTTACATGATTGCTGCAGGCACCATATTTATTTCTGTGCT CCAGGTCTCTAAAGGTCCTAATCCAGTCCTGACCAAACAGACTAGTGATGGACCATCGTGAGCTTCTCTC AGGAGAAATATCAAGAGGGAGGCCAACCTGTAATCATAAGAACTTCTGCTATTTTAATGCCATTCATCAG ACTACAGTCAATCACCATGCTTCTGGCTTTTTGTCTATCTCTGCTGTCTTGTACATCCTGAGATAGTCCA TTCTGAGAACTGTACCCTAGATCTTGTATTGCCTGATGCCTGTCAAAGATGTAATCCATGCTGCTTAAGT GAGGTTGTGCACACAAATCACCATATCTCCTGCAAGTTTGGATTTTGATTCAGTAGTTCGATGGTGGGGT TTGAGATTCTGCATTTCTAATAAGCTCCCAGATGTGGCTGGTGCTGCTGGTCCATGAAACACACTTTGAG TAGCAAGAGGTGATCTGTAGCTCAGTATTGGTCCTTTAAGTTCCCTCAAACATATATAGAGAAAAGGTCC TAAATATTGCAAATTCTCTCAAAGTTTGTCAAGCTATATTGGAATTCTCTCAAAGTCTGTCAAGCTCTAT TGTAGAAAATCAAATTTTTATTGGGAAAAAGCCTACCCCATATTTACTTACAGATAAAGTACTTTTAGGA TCATTCAAGGCACACACCCATAACACTGAGTATGTAAGACAGAAATGCTCTCTCTGGAAATTACAGCAGT GCTGGTGCTGGGATGCCATGATGAGGAGTGTGTGGCCCACAATCATGTAGACCTTGGGAAAACCTGGATT AAAATGATTTTGCGTCATCCTGGCCCTGTATAAGATACATATCAGAATGAAAACCACTCCCAGTGTGACT TTGAATTGCTTTTCCATTTTTTCTTCTTGGGATTAGAGAGCTTCACTTAGATTTCATCTAAGCTGTGATG TTGTACGTTGACCTGATTTACCTAAAATGTCTTTCCTCTCCTTTCAGCTCTGTCTGATCTGGAGCTCGCA GCCCAGTCAATAATCTTCATTTTTGCTGGCTATGAAACCACCAGCAGTGTTCTTTCCTTCACTTTATATG AACTGGCCACTCACCCTGATGTCCAGCAGAAACTGCAAAAGGAGATTGATGCAGTTTTGCCCAATAAGGT GAGGGGATGACCCCTGGAGATGAAGGGAAGAGGTGAAGCCTTAGCAAAAATGCCTCCTCACCACTCCCCA GGAGAATTTTTATAAAAAGCATAATCACTGATTCCTTCACTGACATAATGTAGGAAGCCTCTGAGGAGAA AAACAAAGGGAGAAACATAGAGAACGGTTGCTACTGGCAGAAGCATAAGATCTTTGTACAATATTGCTGG CCCTGGTTCACCTGTTTACTGTTATCACAATAATGCTAAGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAGGAGTGTGGCGAGAAGATGGCCAAACAGGAACAGCTCCAGTCTACAGCTCCCAGCGTGAGCAACACAG AAGACGAATGATTTCTGCATTTCCAACTGAGGTACCGGGTGCATCTCAATGGGGATTGTTGGAGAGTGGG TGCAGGACAGTGGGTGCAGTGCACCCAGCCTGAGCCAAAGCAGGGCGAGGCATCACCTCACCTGGGAAGT GCAAGGGGTCAGGGAATTCCCTTTCCTAGGGGTGACGGACAGCACCTGGAAAATCAGGTCACTCCCACCC TAATACTGCGCTTTTCTGATGGTCTTAGCAAACGGCACACCAGGAGATTATATCCCGCGCATGGCTCGGA GGGTCCTACGCCCATGGAGCCTCGCTCATTGCTAGCACAGCAGTCTGAGATCGAACTGCAAGGCAGCAGC AAGGCTGGGGGAGGGGCGCCCGCCATTGCTAAGGCTTGAGTAGGTAAACAAAGCTGCCAGGAAGCTCAAA CTGGGTGAAGCCCACCGCAGCTCAAGGAGGTCTGCCTGCCTCTGTAGACTCCACCTCTAGGGGCAGAGCA TAGCCAACCAAAAGGCAGCAGAAACCTCTGCAGACTTAAATGTCCCTGTCTGACAGCTTTGAAGAGAGTA GTGGTTCTCCCAGCACACAGCTGGAGATCTGAGAACAGACAGACTGCCTCCTCAAGTGGGTCCCTGACCC CCGAGCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACGGCCGGGTACTCCTC TGAGACAAAACTTCCAGAGGAATGATCAGGCAGCAGCATTTGCGGGTCACCAATACCGCTGTTCTGCAGC CTCCACTCCTGATACCCAGGCAAACAGGGTCTGGAGTGGACCTCCGGCAAACTCCAACAGACCTGCAGCT GAGGATCCTGACTGTCAGAAGGAAAACTAACAAACAGAAAGGACATCCACACCAAAACCCATCTGTACAT CACCATCATCAAAGATCAAAGGTAGATAAAAACACAAAGATGGGGGAAAAACAGCAGAAAAACTGAAAAA TCTAAAAATCAGAGCACCTCTCCTCCTCCAAAGGAACGCAGCTCCGCACCAGCAACGGAAAGCTGGATGG AGAATGACTTTGACGAGTTGAGAGAAGAAGGCTTCAGACGATCAAACTACTCCGAGCTAAAGGAGGAAGT TCGAACCCATGGCAAAGAAGTTAAAAACCTTGAAAAAAGATTAGACAAATGGCTAACTAGAATAATCAAT GCAGAGAAGTCCTTAAAGGACCTGATGGAGCTGAAGACCATGGCACGAGAACTACGTGATGAATGCACAA GCCTCAGTAGCCAATTCAATCAACTGGAAGAAAGGGTATCAGTGATGGAAGATCAAATGAATGAAATGAA GAAAGAAGAGAAGTTTAGAAGAAAAAGAATAAAAAGAAAGGAACAAAGCCTCCAAGAAATATGGGACTAT GTGAAAAGACCAAATCTACGTCTGATTGGTGTACCTGAAAGTGACGGGGAGAATAGAACGAAGTTGGAAA ACACTCTGCAGGATATTATCCAGGAGAACTTCCCCAATCTAGCAAGGCAGGCCAACATTCAAATTCAGGA AATACAGAGAACGCCACAAAGATACTCCTCGAGAAGAGCAACTCCAAGACACATAATTGTCAGATTCACC AAAGTTGAAATGAAGGAAAAAATGTTAAGGGCAGCCAGAGAGAAAGGTCGGGTTACCCACAAACACAAAC CCATCAGACTAACAGTGGATCTCTCGGCAGAAACTCTACAAGCCAGTAGAGAGTGGGGGCCAATATTCAA CATTCTTAAAGAAAAGAATTTTCAACCCAGAATTTCATTTCCAGCCAAACTAAGCTTCATAAGTGAAGGA GAAATAAAATACTTTACAGACAAGCAAATGCTGAGAGATTTTGTCACCACCAGGCCTGCCCTAAAAGAGC TCTTGAAGGAAGCACTAAACATGGAAAGGAACAACTGGTACCAGCCACTGCAAAAACATGCCAAATTGTA AAGACCATCGAGGCTAAGGAGAAACTGCATCAACTAACGAGCAAAATAATCAGCTAACATCATAATGACA GGATCAAATTCACATATAAAAATATTAACCTTAAATGTAAACGGGCTAAATGCTCCAATTAAAAGACACA GACTGGCAAACTGGATAGAGTCAAGACCCATCGGTGTGCTGTATTCAGGAAACCCATCTCACGTGCAAAG TAACACATAGGCTCAAAATAAAGGGATGGAGGAAGATCTACCAAGCAAATGGACAACAAAAAAAGGCAGG GGTTGCAATCCTACTCTCTGATAAAACAGGCTTTAAACCAACAAAGATCAAAAGAGACAAAGAAGGCCAT TACATAATGGTAAAGGGATCAATTCAACAAGAAGAGCTAACTATCCTAAATATATATGCACCCAATACAG GAGCACCCAGATTCATGAAGCAAGTCTTTAGAGACTTACAAAGAGAGTTAGACTCCCACACAATAATAAT GGAAGACTTTAACACCACACTGTCAACACTAGACAGATCAACAGGACAGAAAGTTAAGAAGGATATCCAG GAATTGAACTCAGCTCTGCACAAAGTGGACATAATAGACATCTACAGAACTCTCCACCCCAAATCAACAG AATATACATTCTTTTCAGCACCACACCACACCTATTCCAAAATTAACCACATAGTTGGAAGTAAAGCACT CCTCAGCAAATGTAAAAGAACAGACATTATAACAAACTGTCTCTCAGACCACAGTGCAATCAAACTAGAA CTCAGGATTCAGAAACTCACTCAAAACCGCTCAACTACATGGAAACTGAACAACCTGCTCCTGAATGACT ACTGGGTACATAACGAAATGAAGGCAGAAATAAAGATGTTCTTTGAAACCAACAAGAACAAAGACACAAC ATACCAGAATCTCTGGGCCACATTCAAAGCAATGTGTAGAGGGAAATTTATAGCACTAAATGCCTACAAG AGAAAGCAGGAAAGATCTAACATTGACACCCTAACATCACAATGAAAAGAACTAGAGAAGCAGGAGCAAA CACATTCAAAAGATAGCAGAAGGCAAGAAATAACTAAGATCAGAGCAGAACTGAAGGAAACAGAGACACA AAAAAACCCTTCAAAAAAATCAATGAATCCAGGAGCTGGTTTTTTGAAAAGATCAACAAAATTGATAGAA TGCTAGCAAGACTAATAAAGAAGAAAAGAGAGAAGAATCAAATAGATGCAATAAAAATGATAAAGGGGAT ATCACCACCCATCCCACAGAAATACAAACTACCATCAGAGAATACTATAAACACCTCTATGCAAATAAAC TAGAAAATCTAGAAGAAATGGATAAATTCCTCGACACATACACTCTCCCAAGACTAAACCAGGAAGAAGT TGAAACTCTGAATAGACCAATAACAGGTTCTGAAATTGAGGCAATAATTAATAGCTTACCAACCAAAAAA AGTCCAGGACCAGATGGATTCACCGCCGAATTCTACCAGAGGTACAAGGAGGACCTGGTACCATTCTTTC TGAAACTATTCCAATCAATAGAAAAAGAGGGAATCCTCCCTAACTCATTTTATGAGGCCAGCATCATCCT GATACCAAAGCCTGGCAGAGACACAACCAAAAAAGAGAATTTTAGACCAATATCCCTGATGAACAGTGAT ACAAAAATCCTCAATAAAATACTGGCAAACCGAATCCAGCAGCACATCAAAAAGCTTATCCACCATGATC AAGTGGGCTTCATCCCTGGGATGCAAGGCTGGTTCAACATACGCAAATCAATAAACATAATCCAGCATAT AAACAGAACCAACGACAAAACCCACATGATTATCTCAATAGATGCAGAAAAGGCCTTTAACAAAATTCAA CAGCCCTTCATGCTAAAAACTCTGAATAAATTAGGTATTGATGGAACCTATCTCAAAATAATAAGAGCAA ATTTATGACAAACCCACAGCCAATATCATACTGAATGGACAAAAACTGGAATCATTCCCTTTGAAAACTG GCACAAGACAGGGATGCCCTCTCTCACCACTCCTATTCAACATAGTGTTGGAAGTTCTGGCCAGGGCAAT CAGGCAAGAGAAAGAAATAAAGGGTATTCAATTAGGAAAAGAGGAAGTCAAATTGTCCCTGTTTGCAGAT GACATGATTGTATATCTAGAAAACCCCATCGTCTCAGCCCAAAATCTCCTTAAGCTGATAAACAACTTCA GCAAAGTATCAGGATACAAAATCAATGTGCAAAAATCACAAATATTCTTATACACCAATAACAGACAAAC AGAGAGCCAAATCATGAGTGAACTCCCATTCACAATTGCTTCAAAGACAATAAAATACCTAGGAATTCAA CTTACAAGGGATGTGAAGGACCTCTTCAAGGAGAATTACAAACCACTGCTCAATGAAATAAAAGAAGATA CAAACAAATGGAACAACATTCCATGCTCATGGGTAGGAAGAATCAATATCATGAAAATGGCCATACTGCC CAAGGTAATTTATAGATTCAGTGCCATCGCCATCAAGCTACCAATGACTTTCTTCACAGAACTGGAAAAA ACTACTTTAAAGTTCATATGGAACCAAAAAAGAGCCCGCATTGCCAAGTCAATCCTAAGCCAAAAGAACA AAGCCGGAGGCATCATGCTACCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGGTA CTGGTACCAAAACAGAGATATTGATCAATGGAGCAGAACAGAGCCCTGAGAAAGAATGCCACATATCTAC AACCATCTGATCTTTGACAAACCTGACAAAAACAAGCAGTGGGGAAAGGATTCCCTATTTAATAAATGGT GCTGGGAAAACTGGCTAGCCATATATAGAAAGCTGAAACTGGATCCCTTCCTTACACCTTATACAAAAAT TAATTCAAGATGGATTAAAGACTTACATGTTAGACCTAAAACCATAAAAACCCTAGAAGAAAACCTAGGC AATATCATTCAATACAGAGGCATGGGCAAGGACTTCATGTCTAAAACACCAAAAGCAATGGCAACAAAAG CCAAAATTGACAAATGGGATCTAATGAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTACCATCAGAGT GAACAGGCAACCGACAGAATGGGAGAAAATTTTTGCAACCTACTCATCTGACAAAGGGCTAATATCCAGA ATCTACAATGATCTCAAACAAATTTACAAGAAAAAAACACAACCCCATCAACAAGTGGGGGAAGGATATG AACAGACACTTCTCAAAAGACATTTATGCAGCCAATAGACACATGAAAAAATGTTCATCATCACTGGCCA TCAAAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACGCCAGTTAGAATGGCGATCATTAAAAA GTCAGGAAACAACAGGTGCTGGAGAGGATGTGGAGAAAACAGGAACACTTTTACACTGTTGGTGGGACTG TAAACTAGTTCAACCATTGTGGAAGTCAGTGTGGTGATTCCTCAGGGATCTAGAACTAGAAATACCATTT GACCCAGCCATCCCATTACTGGGTATATACCCAAAGGATTATAAATCATCCTGCTATAAACACACATGCA CACTTATGTTTATTGCAGCACTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCAATAATGAT AGACTGGATTAAGAAAATGTGGCACATATACACCATGGAATGCTATGCAGCCATAAAAAATGATGAGTTC ATGTCCTTTGTAGAGACATGGATGAAGCTGGAAACCATCATTCTCAGCAAACTATGGCAAGGACAAAAAA CCAAACACTGTATGTTCTCACTCGTAGGTGGGAATTGAACAATGAGAACACATGGACACAGGAAGGGGAA TATCACACACTGGGGCCTGTTTTGGGGTGGGAGGAGTGGGGAGGGATAGCATTAGGAGATATACCGAATG TTAAATGACGAGTTAATGGGTGCAGCACACCAACATGGCATAGGTATACATATGTAACAAACCTGCACGT TGTGTACATGTACCCTAAAACTTAAAGTATAAAAAAAAAAATTCAAAAACCTCAGTGGCATCTAATGAGA AGCATTTATTGCTCACAAGACTGGATAGTGAGTTCTGCTGATACTGACTGGACTCACTCTGGTCTGGCTA TGGTCTGAGGTAGCCTGGCCCTGGGGGCGCGATGGAGGCTGACTCAGCTCTCCCCACACCTGTCTCATGT TCCAGTCAGGTAGCCACTGGCCAAGAAGCCAAGCTAGGAACCAGGGTATCTGACTCCTGAGCTAAACTCT AACCCTCTACAATACTGCCTCCCAAATATAACACCAAGTGCTAGGTACATATCATCCACAGTTTTCAGAC TTCTGCCCAAACTGGGATTCTTTTTAGTGTGAAGAGACCTGGCCTGTGGGGCTGACCCTGGTGTGGCTGT GAGGCAGACACAAAGGGACATTTACATCCAGTCCTGAAGATTACAGTCCAGCCCTGAAGCAACAACTAGG AAACTATTCCAAAAGGAGGGGATGGGGCTGAGTGTGGGGTTCTATTCTCTTCATAACTTTAACTAGAACT CAAATTGTGTACCTTGGTAGCATCCAATCATAAATTTATTTTGTCGTATTTGTGATAGAAAGGAACAAGT TTATCCACAAATTTATTTATTTATTTATTTATTTATTTATTTATTTGAGACAGGGTCTGACTCTACGACC CAAGCTGGAGGGCAGTGGTGCAATCTCAGCTCACTGCAAACTCTGCCTCCCAGGCTCAAGCCATCCTCCC GCCTCTGTCTCCTGAGTAGCTGGAACTACAGGCACACGCCACCACACCCAGCTAGTTTTTGTATTTTTTG TAGAGATGGGTTTTCACCATGTTTCCCAAGCTGGTCTCAAACTCCTCAAAAGAGTTACCAAGCAGGACTC TGCAACCAATAATCCTTGTGTGAAGAGGATATTTGCTCTTTTCCCTGTTTTTCTTTCTTGGTACAGATGT GTGACCTCTTTTTGAAAGGTGATAGTGACTTTGGTGTATTTTATTTGGTGGTAATGGTCATAGCCCCATT AATCACATTTCTTCCCATGAGAAAGAAAAACCACTACATGGTCATGCTAAGGATTTCAGTCCCTGGGGTG AGGATGGTCTTGAATATCTCCTACATTCATAACTCCTCCACACATCTCAGTAGGTCACTGAGCACATCAA TGGACATGCCAGTTATTAAAATACTTCACGAATACTATGATCATTTACCAGTATGAGTTATTCTCTGGAG CTTCTAATACTTCAATAGTACTGCATGGACTCAGTTGAGAGTTAATTCAAAATCTCAGATTATCCAATTC TGTTTCTTTCCTTCCAGGCACCACCTACCTATGATGCCGTGGTACAGATGGAGTACCTTGACATGGTGGT GAATGAAACACTCAGATTATTCCCAGTTGCTATTAGACTTGAGAGGACTTGCAAGAAAGATGTTGAAATC AATGGGGTATTCATTCCCAAAGGGTCAATGGTGGTGATTCCAACTTATGCTCTTCACCATGACCCAAAGT ACTGGACAGAGCCTGAGGAGTTCCGCCCTGAAAGGTACAAGTCTCCAGGGAAATGGAGCTCACCCTGACC CAGGCTGGTTCAAGCATATTCTGCCTCTCTTAATCTACATGACAATCGTGTGGTTGTACAATCATTTGCT TGTAAGTCTTTTTATCACAAAAAAGTGATAATTATCAAACTTTACAAACCACAGACTAGAAAAAACGAAA CTACATCCATCCACAGTCCCAGCACAAGACAAAGATAATCAATTATGTCCCTGTGGGCATTTTTCTACGC CTATATAGATTTTTAAAAATTAGAATGGTATCACTTTTTATTTGGTTTGAATTGCTGCTTACTTGATTTA ACAGGAAACTATCCACTGACCTATATTACTATAAATATACATATATATGTATATATATAAATATATATAT ATGTATATATTGCATATGCCATAAACCATTTAACCATGATGTTATTTCAGGTGTATAGGCTTTTTATTCC TTTCTGTTTTTTCTATGCTGTGCCCTTTAGCTCTCTGAATTTAACAGAAACTTTAAAACATGCTTCCACA TTCCATTTGCTTTCAACGTTACTTGCTATTTCCTCTGTAGTAATTATAAGAGTGCAGGCTGAGGTCCTGA GAAGTCCTCATCCCTAATGGTTTAAGCCACTTCACTGAAGACACAAGACAGCACAGGTCCTCCTGGTCCT ATCTGTGGCTGCAGTCCTGTGCCAGCTCCCTTATACTCTCAGTAGACATCTCACACACTCCTCCTTGGAG GTGTCTTGAGCATGCTCTTCTGGGAATTCAGGGACAAGGTCAGGCCTTAGGCACAGTTCGCACTCTGGAT ATAGTTGGTGTTTTCCCATTACTGTATTATTAAGCAAAATTTAGAATGAAATTTTTAGGGTACTGGCTGG TGATTCAGGATGCTTGGGATCTAGACTTTCATTAGCCCCTACCTGCAAGTTTGCTGATGGGAGGAACCTT GTCTTGTTGGTCATGGTGTCCCTAGTGCTAGCATGGAGTCTGCACATAATACTTGTTCACAGAGTAAGTC AGAGCTGACCAAGTTCTCTGTTTTCTGGAGTAGAGGACTTCTATGTTTCCTGCAAGCTCAGCACTTCCAC CTCCTGTGGCTGCACTAATACGAAATCAGAGACCACTCGCTGTACTTCACTTTGAATCACTCAGTCACCA AAAAGATAGTGCTTGCCATGTGTCAGGAACTTGGCTAGGCAGGGAGAAATTCATATGATTTATATAAATC CATAAATCCATATGATTTACATAAATCCATAAATTCATGTGATATATACGTATATGTGTGTGTATATATA TATTAGAGAATGTTTGACATATACACAAGTACATGTTACCGACACCAGCCTATAGAATAGTTTTCGTGCA TCTCCATATATCTATCACTGGTTCCAACAGCCATCAATCCATGTTAGCTGCCCCATCCAAATGCCACCAT CACCCTCCTCCTGACTATCATGTTATTTTGAAGCAATAGCCTGTAAATATTTCAGAATGCTCTCCAAAAT ATAAAGACTCCTGTAAAAACATATGACAACAATGCCATTATTACTTTCTTTGAATCAACATTTTTTCCTT AATATAATCAAATATTTAGAAATCAAATTTGAATAAAACATGGGTCAATCTTCAAAGAATTTATAGCTTA ATGGAACAGATCAAGGAAAGCAGGGATGACACTACAGTAGGGTAGCATCATATGCCCATGTAACTTATGT GACTTAAACTATCCTGTAAGGGTGTGGGGGAGAAAGAGAGGAAGAGATGGAGAGAAGAAAAAGGAAGAGA AGGAGGAGGAGAAGGAGGCAGAGGAGAAGGTGGACGGGGAAGGTAGAGAGGAGGAGGAGGGGAATTAGAA AAAAAGAGATGACAGGAGAAGGAAAGGGAAAAATAACAACTTGAAATAGCACAAGACGTTTTCTCCTTCT CCTTTCTCAATGAGCATGTGACCAACACAAGTGTGAGTTGAGGCAGGAATCCACTTTTCCATCCATCAGT CTTATCATTTATGTGCCTTTTATAGTGTGAACACATCACCACCCTGAATATAATTTTAGTGTTTAGAGAT AAATATTATTTGCAACAATATTCATCTCATCTCAAGAAACGCTCCTATAGGGTATGGAGAATTTAAAGGA CCTGTAGGTTATGATGATTATAACGAAATAACCAAAGCAGGATTTCAATGACCAGCCCACAAAAGTATCC TGTGTACTACTGGTTGGGAGGTGGAGGGGGGTTGTTCTTAAGTAAGAACCCCTAACATGTAACTCTGTGG TTTTTATGTTTCATTAACTATTTAATCTACCAATATGGAACTAGGTTCAGTAAGAAGAAGGACAGCATAG ATCCTTACATATACACACCCTTTGGAACTGGACCCAGAAACTGCATTGGCATGAGGTTTGCTCTCATGAA CATGAAACTTGCTCTAATCAGAGTCCTTCAGAACTTCTCCTTCAAACCTTGTAAAGAAACACAGGTCAGT ACACTTTCTGTATGTTTTATTAAGAATTTTTTTAACTGAAGGGTATATATTTTTTAAAAGAATATGCATG TTTATCTTTTAATAATTCATTCTATGGGCCAAAGAACCTACTTGGATCCATCTTTGATCATTAAGGATGC TTCAGTTCTGGACTTCAAAACCTGTAGCATTAAGAACATCATGTAAAGTCCACACAGATTAGCATGACAT GATTATGTGTAGTCTCTTTGAACCTGAGTAAGTTTAAATTCAGTTTCAAGTCAATTGGAAAGAAGTGTTT TGCACAATCATGAAGTGCAATGATTACCTGGCTGTGACTTAAATGGTGTTCTCCATCACCAGAACCTGCA GAAGCTCTCTCATGACAGTGGTTCTCAACCACTAGCTGTATATTGGAATCACCAGGGAGCTTCAAAAATT CATGATGCCTGTGACATCTCAGAAATTCTAAACTAATTAACCCAGAGCGTGACTAGGTTCTGTCATGCTG TCGGGTGAACCCCTGATTAGTTCTCACGTGAAGCCAAGGTGGAGAATGACTAATTTCAGGCATTTCTGGT GGATATGAAGGACTACCATAGAGCAGGGCTATCCTTACTCCTTGACCTTATGTTCCAGGTGATACATTTA AAGAAAGATTTAGAATCTTTTCTCTGAAGAAGTTAAAGAACAGATGTCATTGATTCATATTAAGCAATAG CCTATAAGTCTTATTTCCAGGACCGGTGTATTTAATATGCAACTCTACCCCTTAAGTACACTTTGTGCTT GGGAGAGGAGGAGGATGGAGATGGTTGCCATCTTATCTATGGCTTCAGGGCAGCTGTGTAGCTTTCCTAT GTGTGTATTCAGGCAGGGGGCTCAGCCCTGAGAGAAAGTGGGCCTCTGGCACACCTGGGACAGGGAAGAT ATTCCCTGGCAAGCTCTCAGGCATCTCAGGCTGGCACTTCTTTGTATCCATGGCAATTTGCTTTCCCCTC ACTGAACTGAGATCAGAATGTTACTCTGTTGGTGGCTCCCCCAACAGTGAAGGGGTGACTCAGTGACAAT AGTGCTAGAAGTATGAGTCAAAACACTGTACAACTTGAGAAATTCCCCGTTTGCACTACGCTTGGAAGCC AAGAGGAGATGTTAAAAAGAAAAGAATAATTCTTTCTGAAGACATTTCCCATCATTGCACTTGATGGGTT CAACTGGGAAGGGTTACTAGACTCTGGAAGTTGAAAACTGCCCACATAATTAAACTGTACAACAGCTACT CAGGATTACCTTGCAAGTTTTAACCTATAAAAATTTAACTTTATATAGCACTTCCAAAATAGTTTGCCAT AATACCTACTAATCTGGATTTAATTTTTAAAACTCATCCTTTTAACTTAAGATTTAAATAAAAAAAAAAA AACACGAGTCCACAAGAATTTGTCTCAGGCCTGGCACAGAGTCAGTGCTCCATAAATATTTTGTTAAACG ATGGATGGTGAGTGCTTTTACTATCCAGTATTTACCCAGCTTATAGATTAAGTATGAAGAGTTCAAGATA CATGGTGTTAAGAGTCGTTTTTATATGCTTGCAAAGCATTTTTGTCATATTTTTTCTACTTTGCTTCCAT CTTTTCTTCTTTCACTTCATTTATTAATTCTCCATATGCTTGTTTAACTATTGTAGATCCCCTTGAAATT AGACACGCAAGGACTTCTTCAACCAGAAAAACCCATTGTTCTAAAGGTGGATTCAAGAGATGGAACCCTA AGTGGAGAATGAGTTATTCTAAGGATTTCTACTTTGGTCTTCAAGAAAGCTGTGCCCCAGAACACCAGAG ATTTCAACTTAGTCAATAAAACCTTGAAATAAAGATGGGCTTAATCTAATGTACTGCA Download Select all
Length	31838
OMIM ID	605325
HGNC ID	HGNC:2638
Unigene ID	Hs.571258
Ensembl ID	ENSG00000106258
PharmGKB ID	PA131

mRNA Information

mRNA ID	NM_000777.4
Exon	join(1..201,3819..3912,5442..5494,7348..7447,12962..13075, 13338..13426,14713..14861,15932..16059,17145..17211, 19368..19528,27248..27474,29795..29954,31627..31838)
mRNA Sequence	>1577 CTGCTGTGCAGGGCAGGGAAGCTCCAGGCAAACAGCCCAGCAAACAGCAGCACTCAGCTAAAAG GAAGACTCACAGAACACAGTTGAAGAAGGAAAGTGGCGATGGACCTCATCCCAAATTTGGCGGT GGAAACCTGGCTTCTCCTGGCTGTCAGCCTGGTGCTCCTCTATCTATATGGGACCCGTACACAT GGACTTTTTAAGAGACTGGGAATTCCAGGGCCCACACCTCTGCCTTTGTTGGGAAATGTTTTGT CCTATCGTCAGGGTCTCTGGAAATTTGACACAGAGTGCTATAAAAAGTATGGAAAAATGTGGGG AACGTATGAAGGTCAACTCCCTGTGCTGGCCATCACAGATCCCGACGTGATCAGAACAGTGCTA GTGAAAGAATGTTATTCTGTCTTCACAAATCGAAGGTCTTTAGGCCCAGTGGGATTTATGAAAA GTGCCATCTCTTTAGCTGAGGATGAAGAATGGAAGAGAATACGGTCATTGCTGTCTCCAACCTT CACCAGCGGAAAACTCAAGGAGATGTTCCCCATCATTGCCCAGTATGGAGATGTATTGGTGAGA AACTTGAGGCGGGAAGCAGAGAAAGGCAAGCCTGTCACCTTGAAAGACATCTTTGGGGCCTACA GCATGGATGTGATTACTGGCACATCATTTGGAGTGAACATCGACTCTCTCAACAATCCACAAGA CCCCTTTGTGGAGAGCACTAAGAAGTTCCTAAAATTTGGTTTCTTAGATCCATTATTTCTCTCA ATAATACTCTTTCCATTCCTTACCCCAGTTTTTGAAGCATTAAATGTCTCTCTGTTTCCAAAAG ATACCATAAATTTTTTAAGTAAATCTGTAAACAGAATGAAGAAAAGTCGCCTCAACGACAAACA AAAGCACCGACTAGATTTCCTTCAGCTGATGATTGACTCCCAGAATTCGAAAGAAACTGAGTCC CACAAAGCTCTGTCTGATCTGGAGCTCGCAGCCCAGTCAATAATCTTCATTTTTGCTGGCTATG AAACCACCAGCAGTGTTCTTTCCTTCACTTTATATGAACTGGCCACTCACCCTGATGTCCAGCA GAAACTGCAAAAGGAGATTGATGCAGTTTTGCCCAATAAGGCACCACCTACCTATGATGCCGTG GTACAGATGGAGTACCTTGACATGGTGGTGAATGAAACACTCAGATTATTCCCAGTTGCTATTA GACTTGAGAGGACTTGCAAGAAAGATGTTGAAATCAATGGGGTATTCATTCCCAAAGGGTCAAT GGTGGTGATTCCAACTTATGCTCTTCACCATGACCCAAAGTACTGGACAGAGCCTGAGGAGTTC CGCCCTGAAAGGTTCAGTAAGAAGAAGGACAGCATAGATCCTTACATATACACACCCTTTGGAA CTGGACCCAGAAACTGCATTGGCATGAGGTTTGCTCTCATGAACATGAAACTTGCTCTAATCAG AGTCCTTCAGAACTTCTCCTTCAAACCTTGTAAAGAAACACAGATCCCCTTGAAATTAGACACG CAAGGACTTCTTCAACCAGAAAAACCCATTGTTCTAAAGGTGGATTCAAGAGATGGAACCCTAA GTGGAGAATGAGTTATTCTAAGGATTTCTACTTTGGTCTTCAAGAAAGCTGTGCCCCAGAACAC CAGAGATTTCAACTTAGTCAATAAAACCTTGAAATAAAGATGGGCTTAATCTAATGTACTGC Download Select all
Length	1726

CDS Information

Location	join(131..201,3819..3912,5442..5494,7348..7447, 12962..13075,13338..13426,14713..14861,15932..16059, 17145..17211,19368..19528,27248..27474,29795..29954, 31627..31722)
CDS Sequence	>gi\|306518607:103-1611 Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 5 (CYP3A5), transcript variant 1, mRNA ATGGACCTCATCCCAAATTTGGCGGTGGAAACCTGGCTTCTCCTGGCTGTCAGCCTGGTGCTCCTCTATC TATATGGGACCCGTACACATGGACTTTTTAAGAGACTGGGAATTCCAGGGCCCACACCTCTGCCTTTGTT GGGAAATGTTTTGTCCTATCGTCAGGGTCTCTGGAAATTTGACACAGAGTGCTATAAAAAGTATGGAAAA ATGTGGGGAACGTATGAAGGTCAACTCCCTGTGCTGGCCATCACAGATCCCGACGTGATCAGAACAGTGC TAGTGAAAGAATGTTATTCTGTCTTCACAAATCGAAGGTCTTTAGGCCCAGTGGGATTTATGAAAAGTGC CATCTCTTTAGCTGAGGATGAAGAATGGAAGAGAATACGGTCATTGCTGTCTCCAACCTTCACCAGCGGA AAACTCAAGGAGATGTTCCCCATCATTGCCCAGTATGGAGATGTATTGGTGAGAAACTTGAGGCGGGAAG CAGAGAAAGGCAAGCCTGTCACCTTGAAAGACATCTTTGGGGCCTACAGCATGGATGTGATTACTGGCAC ATCATTTGGAGTGAACATCGACTCTCTCAACAATCCACAAGACCCCTTTGTGGAGAGCACTAAGAAGTTC CTAAAATTTGGTTTCTTAGATCCATTATTTCTCTCAATAATACTCTTTCCATTCCTTACCCCAGTTTTTG AAGCATTAAATGTCTCTCTGTTTCCAAAAGATACCATAAATTTTTTAAGTAAATCTGTAAACAGAATGAA GAAAAGTCGCCTCAACGACAAACAAAAGCACCGACTAGATTTCCTTCAGCTGATGATTGACTCCCAGAAT TCGAAAGAAACTGAGTCCCACAAAGCTCTGTCTGATCTGGAGCTCGCAGCCCAGTCAATAATCTTCATTT TTGCTGGCTATGAAACCACCAGCAGTGTTCTTTCCTTCACTTTATATGAACTGGCCACTCACCCTGATGT CCAGCAGAAACTGCAAAAGGAGATTGATGCAGTTTTGCCCAATAAGGCACCACCTACCTATGATGCCGTG GTACAGATGGAGTACCTTGACATGGTGGTGAATGAAACACTCAGATTATTCCCAGTTGCTATTAGACTTG AGAGGACTTGCAAGAAAGATGTTGAAATCAATGGGGTATTCATTCCCAAAGGGTCAATGGTGGTGATTCC AACTTATGCTCTTCACCATGACCCAAAGTACTGGACAGAGCCTGAGGAGTTCCGCCCTGAAAGGTTCAGT AAGAAGAAGGACAGCATAGATCCTTACATATACACACCCTTTGGAACTGGACCCAGAAACTGCATTGGCA TGAGGTTTGCTCTCATGAACATGAAACTTGCTCTAATCAGAGTCCTTCAGAACTTCTCCTTCAAACCTTG TAAAGAAACACAGATCCCCTTGAAATTAGACACGCAAGGACTTCTTCAACCAGAAAAACCCATTGTTCTA AAGGTGGATTCAAGAGATGGAACCCTAAGTGGAGAATGA Download Select all
CCDS ID	CCDS5672.1

Protein Information

Protein ID	NP_000768.1
Protein Name	Cytochrome P450, family 3, subfamily A, polypeptide 5
Molecular Wt. (Da)	56978
Protein Sequence	>1577 MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTEC YKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKR IRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVN IDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRM KKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYE LATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN GVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFAL MNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRDGTLSGE Download Select all
Length	502
Uniprot ID	P52565
Ensembl Protein ID	ENSP00000269321

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Phosphorylation	347

Enzyme Information

EC	1.14.13.157
Name	1,8-cineole 2-exo-monooxygenase CYP3A4
Class	Oxidoreductases; Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2; With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname	1,8-cineole,NADPH:oxygen oxidoreductase (2-exo-hydroxylating)
Substrate	1,8-cineole [CPD:C09844]; NADPH [CPD:C00005]; H+ [CPD:C00080]; O2
Product	2-exo-hydroxy-1,8-cineole [CPD:C20326]; NADP+ [CPD:C00006]; H2O
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

No matching records from HPRD source could be found.

Pathway Information

Pathway Name	Pathway ID
Chemical carcinogenesis	hsa05204
Drug metabolism - cytochrome P450	hsa00982
Metabolic pathways	hsa01100
Metabolism of xenobiotics by cytochrome P450	hsa00980
Retinol metabolism	hsa00830
Steroid hormone biosynthesis	hsa00140

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
pfam00067	39-492	p450
cl12078	39-492	p450 superfamily
COG2124	35-486	CypX
PLN02290	28-464	PLN02290
PTZ00404	38-472	PTZ00404
PLN02936	66-464	PLN02936
PLN03112	39-466	PLN03112
PLN02183	39-465	PLN02183
PLN02655	38-465	PLN02655
PLN02687	247-489	PLN02687
PLN02394	39-466	PLN02394
PLN03195	121-464	PLN03195
PLN02302	39-473	PLN02302
PLN00168	39-465	PLN00168
PLN02426	300-465	PLN02426
PLN02966	39-465	PLN02966
PLN00110	263-465	PLN00110
PLN02987	33-472	PLN02987
PLN03018	294-495	PLN03018
PLN03234	39-464	PLN03234
PLN02774	251-443	PLN02774
PLN02196	39-455	PLN02196
PLN02971	39-495	PLN02971
PLN02169	298-465	PLN02169
PLN02500	287-465	PLN02500
TIGR04538	268-466	P450_cycloAA_1
PLN03141	359-447	PLN03141
PLN02648	325-419	PLN02648
TIGR04458	375-462	CYP450_TxtE
PLN02738	121-465	PLN02738
TIGR04515	284-418	P450_rel_GT_act

Ontology Information

HPRD ID	3565
Molecular Class	Enzyme: Oxidoreductase
Molecular Function	Molecular function unknown (GO:0005554)
Biological Process	Cell growth and/or maintenance (GO:0008151)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P20815 DB00091 Cyclosporine SmallMoleculeDrug
P20815 DB00175 Pravastatin SmallMoleculeDrug
P20815 DB00176 Fluvoxamine SmallMoleculeDrug
P20815 DB00196 Fluconazole SmallMoleculeDrug
P20815 DB00199 Erythromycin SmallMoleculeDrug
P20815 DB00201 Caffeine SmallMoleculeDrug
P20815 DB00203 Sildenafil SmallMoleculeDrug
P20815 DB00206 Reserpine SmallMoleculeDrug
P20815 DB00220 Nelfinavir SmallMoleculeDrug
P20815 DB00224 Indinavir SmallMoleculeDrug
P20815 DB00227 Lovastatin SmallMoleculeDrug
P20815 DB00238 Nevirapine SmallMoleculeDrug
P20815 DB00246 Ziprasidone SmallMoleculeDrug
P20815 DB00250 Dapsone SmallMoleculeDrug
P20815 DB00252 Phenytoin SmallMoleculeDrug
P20815 DB00278 Argatroban SmallMoleculeDrug
P20815 DB00281 Lidocaine SmallMoleculeDrug
P20815 DB00313 Valproic Acid SmallMoleculeDrug
P20815 DB00317 Gefitinib SmallMoleculeDrug
P20815 DB00318 Codeine SmallMoleculeDrug
P20815 DB00321 Amitriptyline SmallMoleculeDrug
P20815 DB00333 Methadone SmallMoleculeDrug
P20815 DB00343 Diltiazem SmallMoleculeDrug
P20815 DB00381 Amlodipine SmallMoleculeDrug
P20815 DB00393 Nimodipine SmallMoleculeDrug
P20815 DB00394 Beclomethasone SmallMoleculeDrug
P20815 DB00396 Progesterone SmallMoleculeDrug
P20815 DB00398 Sorafenib SmallMoleculeDrug
P20815 DB00401 Nisoldipine SmallMoleculeDrug
P20815 DB00404 Alprazolam SmallMoleculeDrug
P20815 DB00425 Zolpidem SmallMoleculeDrug
P20815 DB00444 Teniposide SmallMoleculeDrug
P20815 DB00446 Chloramphenicol SmallMoleculeDrug
P20815 DB00468 Quinine SmallMoleculeDrug
P20815 DB00472 Fluoxetine SmallMoleculeDrug
P20815 DB00490 Buspirone SmallMoleculeDrug
P20815 DB00497 Oxycodone SmallMoleculeDrug
P20815 DB00499 Flutamide SmallMoleculeDrug
P20815 DB00501 Cimetidine SmallMoleculeDrug
P20815 DB00502 Haloperidol SmallMoleculeDrug
P20815 DB00503 Ritonavir SmallMoleculeDrug
P20815 DB00514 Dextromethorphan SmallMoleculeDrug
P20815 DB00528 Lercanidipine SmallMoleculeDrug
P20815 DB00530 Erlotinib SmallMoleculeDrug
P20815 DB00531 Cyclophosphamide SmallMoleculeDrug
P20815 DB00537 Ciprofloxacin SmallMoleculeDrug
P20815 DB00540 Nortriptyline SmallMoleculeDrug
P20815 DB00541 Vincristine SmallMoleculeDrug
P20815 DB00564 Carbamazepine SmallMoleculeDrug
P20815 DB00571 Propranolol SmallMoleculeDrug
P20815 DB00575 Clonidine SmallMoleculeDrug
P20815 DB00582 Voriconazole SmallMoleculeDrug
P20815 DB00588 Fluticasone Propionate SmallMoleculeDrug
P20815 DB00593 Ethosuximide SmallMoleculeDrug
P20815 DB00604 Cisapride SmallMoleculeDrug
P20815 DB00608 Chloroquine SmallMoleculeDrug
P20815 DB00619 Imatinib SmallMoleculeDrug
P20815 DB00622 Nicardipine SmallMoleculeDrug
P20815 DB00624 Testosterone SmallMoleculeDrug
P20815 DB00637 Astemizole SmallMoleculeDrug
P20815 DB00641 Simvastatin SmallMoleculeDrug
P20815 DB00655 Estrone SmallMoleculeDrug
P20815 DB00656 Trazodone SmallMoleculeDrug
P20815 DB00661 Verapamil SmallMoleculeDrug
P20815 DB00673 Aprepitant SmallMoleculeDrug
P20815 DB00675 Tamoxifen SmallMoleculeDrug
P20815 DB00678 Losartan SmallMoleculeDrug
P20815 DB00683 Midazolam SmallMoleculeDrug
P20815 DB00688 Mycophenolate mofetil SmallMoleculeDrug
P20815 DB00694 Daunorubicin SmallMoleculeDrug
P20815 DB00700 Eplerenone SmallMoleculeDrug
P20815 DB00701 Amprenavir SmallMoleculeDrug
P20815 DB00705 Delavirdine SmallMoleculeDrug
P20815 DB00717 Norethindrone SmallMoleculeDrug
P20815 DB00731 Nateglinide SmallMoleculeDrug
P20815 DB00734 Risperidone SmallMoleculeDrug
P20815 DB00738 Pentamidine SmallMoleculeDrug
P20815 DB00741 Hydrocortisone SmallMoleculeDrug
P20815 DB00745 Modafinil SmallMoleculeDrug
P20815 DB00755 Tretinoin SmallMoleculeDrug
P20815 DB00758 Clopidogrel SmallMoleculeDrug
P20815 DB00762 Irinotecan SmallMoleculeDrug
P20815 DB00773 Etoposide SmallMoleculeDrug
P20815 DB00776 Oxcarbazepine SmallMoleculeDrug
P20815 DB00780 Phenelzine SmallMoleculeDrug
P20815 DB00783 Estradiol SmallMoleculeDrug
P20815 DB00795 Sulfasalazine SmallMoleculeDrug
P20815 DB00802 Alfentanil SmallMoleculeDrug
P20815 DB00813 Fentanyl SmallMoleculeDrug
P20815 DB00822 Disulfiram SmallMoleculeDrug
P20815 DB00829 Diazepam SmallMoleculeDrug
P20815 DB00834 Mifepristone SmallMoleculeDrug
P20815 DB00842 Oxazepam SmallMoleculeDrug
P20815 DB00862 Vardenafil SmallMoleculeDrug
P20815 DB00863 Ranitidine SmallMoleculeDrug
P20815 DB00864 Tacrolimus SmallMoleculeDrug
P20815 DB00877 Sirolimus SmallMoleculeDrug
P20815 DB00889 Granisetron SmallMoleculeDrug
P20815 DB00897 Triazolam SmallMoleculeDrug
P20815 DB00904 Ondansetron SmallMoleculeDrug
P20815 DB00907 Cocaine SmallMoleculeDrug
P20815 DB00921 Buprenorphine SmallMoleculeDrug
P20815 DB00938 Salmeterol SmallMoleculeDrug
P20815 DB00943 Zalcitabine SmallMoleculeDrug
P20815 DB00962 Zaleplon SmallMoleculeDrug
P20815 DB00972 Azelastine SmallMoleculeDrug
P20815 DB00976 Telithromycin SmallMoleculeDrug
P20815 DB01023 Felodipine SmallMoleculeDrug
P20815 DB01026 Ketoconazole SmallMoleculeDrug
P20815 DB01041 Thalidomide SmallMoleculeDrug
P20815 DB01045 Rifampicin SmallMoleculeDrug
P20815 DB01054 Nitrendipine SmallMoleculeDrug
P20815 DB01058 Praziquantel SmallMoleculeDrug
P20815 DB01059 Norfloxacin SmallMoleculeDrug
P20815 DB01062 Oxybutynin SmallMoleculeDrug
P20815 DB01076 Atorvastatin SmallMoleculeDrug
P20815 DB01095 Fluvastatin SmallMoleculeDrug
P20815 DB01098 Rosuvastatin SmallMoleculeDrug
P20815 DB01100 Pimozide SmallMoleculeDrug
P20815 DB01103 Quinacrine SmallMoleculeDrug
P20815 DB01114 Chlorphenamine SmallMoleculeDrug
P20815 DB01115 Nifedipine SmallMoleculeDrug
P20815 DB01118 Amiodarone SmallMoleculeDrug
P20815 DB01126 Dutasteride SmallMoleculeDrug
P20815 DB01149 Nefazodone SmallMoleculeDrug
P20815 DB01166 Cilostazol SmallMoleculeDrug
P20815 DB01167 Itraconazole SmallMoleculeDrug
P20815 DB01174 Phenobarbital SmallMoleculeDrug
P20815 DB01181 Ifosfamide SmallMoleculeDrug
P20815 DB01184 Domperidone SmallMoleculeDrug
P20815 DB01201 Rifapentine SmallMoleculeDrug
P20815 DB01211 Clarithromycin SmallMoleculeDrug
P20815 DB01216 Finasteride SmallMoleculeDrug
P20815 DB01218 Halofantrine SmallMoleculeDrug
P20815 DB01224 Quetiapine SmallMoleculeDrug
P20815 DB01227 Levomethadyl Acetate SmallMoleculeDrug
P20815 DB01229 Paclitaxel SmallMoleculeDrug
P20815 DB01232 Saquinavir SmallMoleculeDrug
P20815 DB01234 Dexamethasone SmallMoleculeDrug
P20815 DB01238 Aripiprazole SmallMoleculeDrug
P20815 DB01248 Docetaxel SmallMoleculeDrug
P20815 DB01254 Dasatinib SmallMoleculeDrug
P20815 DB01259 Lapatinib SmallMoleculeDrug
P20815 DB01268 Sunitinib SmallMoleculeDrug
P20815 DB01361 Troleandomycin SmallMoleculeDrug
P20815 DB04946 Iloperidone SmallMoleculeDrug
P20815 DB05239 Cobimetinib SmallMoleculeDrug
P20815 DB05773 ado-trastuzumab emtansine SmallMoleculeDrug
P20815 DB06228 Rivaroxaban SmallMoleculeDrug
P20815 DB06267 Udenafil SmallMoleculeDrug
P20815 DB06287 Temsirolimus SmallMoleculeDrug
P20815 DB06335 Saxagliptin SmallMoleculeDrug
P20815 DB06403 Ambrisentan SmallMoleculeDrug
P20815 DB06413 Armodafinil SmallMoleculeDrug
P20815 DB06605 Apixaban SmallMoleculeDrug
P20815 DB06626 Axitinib SmallMoleculeDrug
P20815 DB06697 Artemether SmallMoleculeDrug
P20815 DB06730 Gestodene SmallMoleculeDrug
P20815 DB06772 Cabazitaxel SmallMoleculeDrug
P20815 DB08865 Crizotinib SmallMoleculeDrug
P20815 DB08870 Brentuximab vedotin BiotechDrug
P20815 DB08873 Boceprevir SmallMoleculeDrug
P20815 DB08883 Perampanel SmallMoleculeDrug
P20815 DB08899 Enzalutamide SmallMoleculeDrug
P20815 DB08901 Ponatinib SmallMoleculeDrug
P20815 DB08930 Dolutegravir SmallMoleculeDrug
P20815 DB09053 Ibrutinib SmallMoleculeDrug
P20815 DB09068 Vortioxetine SmallMoleculeDrug
P20815 DB09102 Daclatasvir SmallMoleculeDrug
P20815 DB01267 Paliperidone SmallMoleculeDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

Uniprot ID	DrugBank ID	Name	Type
P20815	DB00091	Cyclosporine	SmallMoleculeDrug
P20815	DB00175	Pravastatin	SmallMoleculeDrug
P20815	DB00176	Fluvoxamine	SmallMoleculeDrug
P20815	DB00196	Fluconazole	SmallMoleculeDrug
P20815	DB00199	Erythromycin	SmallMoleculeDrug
P20815	DB00201	Caffeine	SmallMoleculeDrug
P20815	DB00203	Sildenafil	SmallMoleculeDrug
P20815	DB00206	Reserpine	SmallMoleculeDrug
P20815	DB00220	Nelfinavir	SmallMoleculeDrug
P20815	DB00224	Indinavir	SmallMoleculeDrug
P20815	DB00227	Lovastatin	SmallMoleculeDrug
P20815	DB00238	Nevirapine	SmallMoleculeDrug
P20815	DB00246	Ziprasidone	SmallMoleculeDrug
P20815	DB00250	Dapsone	SmallMoleculeDrug
P20815	DB00252	Phenytoin	SmallMoleculeDrug
P20815	DB00278	Argatroban	SmallMoleculeDrug
P20815	DB00281	Lidocaine	SmallMoleculeDrug
P20815	DB00313	Valproic Acid	SmallMoleculeDrug
P20815	DB00317	Gefitinib	SmallMoleculeDrug
P20815	DB00318	Codeine	SmallMoleculeDrug
P20815	DB00321	Amitriptyline	SmallMoleculeDrug
P20815	DB00333	Methadone	SmallMoleculeDrug
P20815	DB00343	Diltiazem	SmallMoleculeDrug
P20815	DB00381	Amlodipine	SmallMoleculeDrug
P20815	DB00393	Nimodipine	SmallMoleculeDrug
P20815	DB00394	Beclomethasone	SmallMoleculeDrug
P20815	DB00396	Progesterone	SmallMoleculeDrug
P20815	DB00398	Sorafenib	SmallMoleculeDrug
P20815	DB00401	Nisoldipine	SmallMoleculeDrug
P20815	DB00404	Alprazolam	SmallMoleculeDrug
P20815	DB00425	Zolpidem	SmallMoleculeDrug
P20815	DB00444	Teniposide	SmallMoleculeDrug
P20815	DB00446	Chloramphenicol	SmallMoleculeDrug
P20815	DB00468	Quinine	SmallMoleculeDrug
P20815	DB00472	Fluoxetine	SmallMoleculeDrug
P20815	DB00490	Buspirone	SmallMoleculeDrug
P20815	DB00497	Oxycodone	SmallMoleculeDrug
P20815	DB00499	Flutamide	SmallMoleculeDrug
P20815	DB00501	Cimetidine	SmallMoleculeDrug
P20815	DB00502	Haloperidol	SmallMoleculeDrug
P20815	DB00503	Ritonavir	SmallMoleculeDrug
P20815	DB00514	Dextromethorphan	SmallMoleculeDrug
P20815	DB00528	Lercanidipine	SmallMoleculeDrug
P20815	DB00530	Erlotinib	SmallMoleculeDrug
P20815	DB00531	Cyclophosphamide	SmallMoleculeDrug
P20815	DB00537	Ciprofloxacin	SmallMoleculeDrug
P20815	DB00540	Nortriptyline	SmallMoleculeDrug
P20815	DB00541	Vincristine	SmallMoleculeDrug
P20815	DB00564	Carbamazepine	SmallMoleculeDrug
P20815	DB00571	Propranolol	SmallMoleculeDrug
P20815	DB00575	Clonidine	SmallMoleculeDrug
P20815	DB00582	Voriconazole	SmallMoleculeDrug
P20815	DB00588	Fluticasone Propionate	SmallMoleculeDrug
P20815	DB00593	Ethosuximide	SmallMoleculeDrug
P20815	DB00604	Cisapride	SmallMoleculeDrug
P20815	DB00608	Chloroquine	SmallMoleculeDrug
P20815	DB00619	Imatinib	SmallMoleculeDrug
P20815	DB00622	Nicardipine	SmallMoleculeDrug
P20815	DB00624	Testosterone	SmallMoleculeDrug
P20815	DB00637	Astemizole	SmallMoleculeDrug
P20815	DB00641	Simvastatin	SmallMoleculeDrug
P20815	DB00655	Estrone	SmallMoleculeDrug
P20815	DB00656	Trazodone	SmallMoleculeDrug
P20815	DB00661	Verapamil	SmallMoleculeDrug
P20815	DB00673	Aprepitant	SmallMoleculeDrug
P20815	DB00675	Tamoxifen	SmallMoleculeDrug
P20815	DB00678	Losartan	SmallMoleculeDrug
P20815	DB00683	Midazolam	SmallMoleculeDrug
P20815	DB00688	Mycophenolate mofetil	SmallMoleculeDrug
P20815	DB00694	Daunorubicin	SmallMoleculeDrug
P20815	DB00700	Eplerenone	SmallMoleculeDrug
P20815	DB00701	Amprenavir	SmallMoleculeDrug
P20815	DB00705	Delavirdine	SmallMoleculeDrug
P20815	DB00717	Norethindrone	SmallMoleculeDrug
P20815	DB00731	Nateglinide	SmallMoleculeDrug
P20815	DB00734	Risperidone	SmallMoleculeDrug
P20815	DB00738	Pentamidine	SmallMoleculeDrug
P20815	DB00741	Hydrocortisone	SmallMoleculeDrug
P20815	DB00745	Modafinil	SmallMoleculeDrug
P20815	DB00755	Tretinoin	SmallMoleculeDrug
P20815	DB00758	Clopidogrel	SmallMoleculeDrug
P20815	DB00762	Irinotecan	SmallMoleculeDrug
P20815	DB00773	Etoposide	SmallMoleculeDrug
P20815	DB00776	Oxcarbazepine	SmallMoleculeDrug
P20815	DB00780	Phenelzine	SmallMoleculeDrug
P20815	DB00783	Estradiol	SmallMoleculeDrug
P20815	DB00795	Sulfasalazine	SmallMoleculeDrug
P20815	DB00802	Alfentanil	SmallMoleculeDrug
P20815	DB00813	Fentanyl	SmallMoleculeDrug
P20815	DB00822	Disulfiram	SmallMoleculeDrug
P20815	DB00829	Diazepam	SmallMoleculeDrug
P20815	DB00834	Mifepristone	SmallMoleculeDrug
P20815	DB00842	Oxazepam	SmallMoleculeDrug
P20815	DB00862	Vardenafil	SmallMoleculeDrug
P20815	DB00863	Ranitidine	SmallMoleculeDrug
P20815	DB00864	Tacrolimus	SmallMoleculeDrug
P20815	DB00877	Sirolimus	SmallMoleculeDrug
P20815	DB00889	Granisetron	SmallMoleculeDrug
P20815	DB00897	Triazolam	SmallMoleculeDrug
P20815	DB00904	Ondansetron	SmallMoleculeDrug
P20815	DB00907	Cocaine	SmallMoleculeDrug
P20815	DB00921	Buprenorphine	SmallMoleculeDrug
P20815	DB00938	Salmeterol	SmallMoleculeDrug
P20815	DB00943	Zalcitabine	SmallMoleculeDrug
P20815	DB00962	Zaleplon	SmallMoleculeDrug
P20815	DB00972	Azelastine	SmallMoleculeDrug
P20815	DB00976	Telithromycin	SmallMoleculeDrug
P20815	DB01023	Felodipine	SmallMoleculeDrug
P20815	DB01026	Ketoconazole	SmallMoleculeDrug
P20815	DB01041	Thalidomide	SmallMoleculeDrug
P20815	DB01045	Rifampicin	SmallMoleculeDrug
P20815	DB01054	Nitrendipine	SmallMoleculeDrug
P20815	DB01058	Praziquantel	SmallMoleculeDrug
P20815	DB01059	Norfloxacin	SmallMoleculeDrug
P20815	DB01062	Oxybutynin	SmallMoleculeDrug
P20815	DB01076	Atorvastatin	SmallMoleculeDrug
P20815	DB01095	Fluvastatin	SmallMoleculeDrug
P20815	DB01098	Rosuvastatin	SmallMoleculeDrug
P20815	DB01100	Pimozide	SmallMoleculeDrug
P20815	DB01103	Quinacrine	SmallMoleculeDrug
P20815	DB01114	Chlorphenamine	SmallMoleculeDrug
P20815	DB01115	Nifedipine	SmallMoleculeDrug
P20815	DB01118	Amiodarone	SmallMoleculeDrug
P20815	DB01126	Dutasteride	SmallMoleculeDrug
P20815	DB01149	Nefazodone	SmallMoleculeDrug
P20815	DB01166	Cilostazol	SmallMoleculeDrug
P20815	DB01167	Itraconazole	SmallMoleculeDrug
P20815	DB01174	Phenobarbital	SmallMoleculeDrug
P20815	DB01181	Ifosfamide	SmallMoleculeDrug
P20815	DB01184	Domperidone	SmallMoleculeDrug
P20815	DB01201	Rifapentine	SmallMoleculeDrug
P20815	DB01211	Clarithromycin	SmallMoleculeDrug
P20815	DB01216	Finasteride	SmallMoleculeDrug
P20815	DB01218	Halofantrine	SmallMoleculeDrug
P20815	DB01224	Quetiapine	SmallMoleculeDrug
P20815	DB01227	Levomethadyl Acetate	SmallMoleculeDrug
P20815	DB01229	Paclitaxel	SmallMoleculeDrug
P20815	DB01232	Saquinavir	SmallMoleculeDrug
P20815	DB01234	Dexamethasone	SmallMoleculeDrug
P20815	DB01238	Aripiprazole	SmallMoleculeDrug
P20815	DB01248	Docetaxel	SmallMoleculeDrug
P20815	DB01254	Dasatinib	SmallMoleculeDrug
P20815	DB01259	Lapatinib	SmallMoleculeDrug
P20815	DB01268	Sunitinib	SmallMoleculeDrug
P20815	DB01361	Troleandomycin	SmallMoleculeDrug
P20815	DB04946	Iloperidone	SmallMoleculeDrug
P20815	DB05239	Cobimetinib	SmallMoleculeDrug
P20815	DB05773	ado-trastuzumab emtansine	SmallMoleculeDrug
P20815	DB06228	Rivaroxaban	SmallMoleculeDrug
P20815	DB06267	Udenafil	SmallMoleculeDrug
P20815	DB06287	Temsirolimus	SmallMoleculeDrug
P20815	DB06335	Saxagliptin	SmallMoleculeDrug
P20815	DB06403	Ambrisentan	SmallMoleculeDrug
P20815	DB06413	Armodafinil	SmallMoleculeDrug
P20815	DB06605	Apixaban	SmallMoleculeDrug
P20815	DB06626	Axitinib	SmallMoleculeDrug
P20815	DB06697	Artemether	SmallMoleculeDrug
P20815	DB06730	Gestodene	SmallMoleculeDrug
P20815	DB06772	Cabazitaxel	SmallMoleculeDrug
P20815	DB08865	Crizotinib	SmallMoleculeDrug
P20815	DB08870	Brentuximab vedotin	BiotechDrug
P20815	DB08873	Boceprevir	SmallMoleculeDrug
P20815	DB08883	Perampanel	SmallMoleculeDrug
P20815	DB08899	Enzalutamide	SmallMoleculeDrug
P20815	DB08901	Ponatinib	SmallMoleculeDrug
P20815	DB08930	Dolutegravir	SmallMoleculeDrug
P20815	DB09053	Ibrutinib	SmallMoleculeDrug
P20815	DB09068	Vortioxetine	SmallMoleculeDrug
P20815	DB09102	Daclatasvir	SmallMoleculeDrug
P20815	DB01267	Paliperidone	SmallMoleculeDrug

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO