Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DACT2 | 168002 | dishevelled-binding antagonist of beta-catenin 2 | 6 | bA503C24.7, DAPPER2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25023701 | 2015 | Cell line : SW480, LoVo, LS 180, Caco 2, HT 29, DLD 1, SW620, HCT116, HEK-293, HEK 293T Source : American Type Culture Collection (Manassas, VA, USA). Sample Type : CRC tumor and normal tissue No. of Sample : 67 Stage : - | Fluorescent immunohistochemistry,Dual-luciferase reporter assay,Western blotting,Hematoxylin and eosin staining and immunohistochemistry,Co-immunoprecipitation | Hypermethylation | - | DACT2 acts as a functional tumor suppressor in colon cancer through inhibiting Wnt/?-catenin signaling. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 6 |
| Location | 6q27 |
| Start | 168693510 |
| End | 168720459 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 26950 |
| OMIM ID | 608966 |
| HGNC ID | HGNC:21231 |
| Unigene ID | Hs.673059 |
| Ensembl ID | ENSG00000164488 |
| PharmGKB ID | PA134934623 |
Protein Information
| Protein ID | NP_001273279.1 |
|---|---|
| Protein Name | dishevelled-binding antagonist of beta-catenin 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 774 |
| Uniprot ID | Q8N143 |
| Ensembl Protein ID | ENSP00000293805 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| PRK10920 | 69-119 | PRK10920 |
| cl19375 | 69-119 | HemX superfamily |
| pfam15268 | 26-774 | Dapper |
| pfam04094 | 347-551 | DUF390 |
| PRK04863 | 69-106 | mukB |
Ontology Information
| HPRD ID | 16414 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.