Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DACT3 | 147906 | dishevelled-binding antagonist of beta-catenin 3 | 19 | MGC15476, DAPPER3 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18538736 | 2008 | Cell line : - Source : Singapore Tissue Network. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Immunoblotting,Transfection, immunoprecipitation,Apoptosis and Flow Cytometry ,Microarray real time RT-PCR,DNA methylation analysis,Chromatin immunoprecipitation,Immunofluorescence Staining and Confocal Microscopy | Unknown | - | DACT3 as an important regulator of Wnt/beta-catenin signaling in colorectal cancer and suggests a potential strategy for therapeutic control of Wnt/beta-catenin signaling in colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 19 |
| Location | 19q13.32 |
| Start | 47150869 |
| End | 47164395 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 13527 |
| OMIM ID | 611112 |
| HGNC ID | HGNC:30745 |
| Unigene ID | Hs.515490 |
| Ensembl ID | ENSG00000197380 |
| PharmGKB ID | PA162383145 |
Protein Information
| Protein ID | NP_001287975.1 |
|---|---|
| Protein Name | dishevelled-binding antagonist of beta-catenin 3 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 629 |
| Uniprot ID | Q8TE58 |
| Ensembl Protein ID | ENSP00000299164 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 520 |
| S | Phosphorylation | 426 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam15268 | 20-629 | Dapper |
| PHA03307 | 162-498 | PHA03307 |
| PHA03247 | 108-463 | PHA03247 |
| PRK14951 | 162-304 | PRK14951 |
Ontology Information
| HPRD ID | 6333 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Metallopeptidase activity (GO:0008237) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.