Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DCAF12L2 | 340578 | DDB1 and CUL4 associated factor 12-like 2 | X | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23684749 | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 86 Stage : - | MSI analysis | Mutation | - | Potential mutation hot spots were confirmed in 15 genes; ADAR, DCAF12L2, GLT1D1, ITGA7, MAP1B, MRGPRX4, PSRC1, RANBP2, RPS6KL1, SNCAIP, TCEAL6, TUBB6, WBP5, VEGFB, and ZBTB2 |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | WD repeat domain containing |
| Description | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multi-protein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9. However, the CDS of this intronless gene remains intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein. [provided by RefSeq, May 2010] | Chromosome | X |
| Location | Xq25 |
| Start | 125297482 |
| End | 125300080 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 2599 |
| OMIM ID | - |
| HGNC ID | HGNC:32950 |
| Unigene ID | Hs.181867 |
| Ensembl ID | ENSG00000198354 |
| PharmGKB ID | PA165756531 |
Protein Information
| Protein ID | NP_001013650.1 |
|---|---|
| Protein Name | DDB1 and CUL4 associated factor 12-like 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 463 |
| Uniprot ID | Q9P2K8 |
| Ensembl Protein ID | ENSP00000263791 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00200 | 95-381 | WD40 |
| cl02567 | 95-381 | WD40 superfamily |
| cd00200 | 111-290 | WD40 |
| pfam00400 | 186-220 | WD40 |
| smart00320 | 186-220 | WD40 |
| COG2319 | 152-417 | WD40 |
| COG2319 | 111-295 | WD40 |
| COG2319 | 109-332 | WD40 |
| COG2319 | 160-394 | WD40 |
Ontology Information
| HPRD ID | 18447 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transmembrane receptor protein tyrosine kinase activity (GO:0004714) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.