CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	17	p68; HLR1; G17P1; HUMP68

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20089989	2010	Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and Normal tissue No. of Sample : - Stage : -	Biochemical isolation to nano-LC-MS/MS analysis.	Up-regulation	-	This genes are differenitially expressed between colorectal adenoma and Colorectal cancer tissue. CRC tissue was collected at the VU University Medical Center, Amsterdam, The Netherlands.

Gene Details

Chromosome: 17; NC_000017.10 (62494374..62502484, complement)
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Gene Type	protein coding
Gene Family	DEAD-boxes
Description	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified. [provided by RefSeq, Jul 2008]
Chromosome	17
Location	17q21
Start	64498256
End	64506924
Strand	-
Gene Sequence	>gi\|568815581:c64506924-64498256 Homo sapiens chromosome 17, GRCh38.p2 Primary Assembly ATCAGAGGAGCACTTCCTTTCACAGGACGTGAAACGGGGGCGGTTTGGGAAGTTTAGAGACCATTCTCCG CCGACCAAAACCCGTCAAAGGATTATCAGACACGCGGGTCGGACGGTCCACATCAGCCGGCAGCCCGGGC GGGTCCCGGGGTGCGAGCAGCGCACTTCCGGTGAGCTATTTCGTTTTGTATCCCTCCGCCGACGTCAACG GGAAAGTAGTGCGGACCGCTCTCTCGGTGGTCCGGGGTGGTACAGCCACGTGACAACGCCAGGCCCCGCC TTCCCCCTCTTTTGGTTACAGACGTGAGGGCTCTTTGGAGACGTAAACATCTCCGAGTGGCGAGGGTGGG CGGGGCTGGGCTTGGGAAAGGGCGGGGTGGCTTGCTTGAGGTGTGGAAAGACCAGAAGAAGGTGAGGTCA AGAGAGTGCAGAATGAGGCATTCCAATGGTGGGTGGGCCCTGACCTGAGAGAGTGGCGCGGGGAGGGGTG AAAGCGCGGCGATCCTGGAACGCCAGCGGGCGTTGCGGCCTATGCGCGAGGGGCGGGGCGATTAGGTCAT AGAGCGGCTCCCAGCGTTCCCTGCGGCGTAGGAGGCGGTCCAGACTATAAAAGCGGCTGCCGGAAAGCGG CCGGCACCTCATTCATTTCTACCGGTCTCTAGTAGTGCAGCTTCGGCTGGTGTCATCGGTGTCCTTCCTC CGCTGCCGCCCCCGCAAGGCTTCGCCGTCATCGAGGCCATTTCCAGCGACTTGTCGCACGCTTTTCTATA TACTTCGTTCCCCGCCAACCGCAACCATTGACGCCATGTCGGGTTATTCGAGTGACCGAGACCGCGGCCG GGACCGAGGGTGAGTTTGGGAGCCGAGCTGTCAGGCCTGGCGGGTGGGGGGATGGGAGGGCGGGTCAGGG TGGCGGCCGGCGGGGGCTTTGCGGCTTGGACTTGGCCTTTCCGGGCTATCTTGGGACTTCCTTTCCCGAA GGCTTGCGCCATTTTGATATTCACGTCACAGTGATTGGAAGAGATTTGACGGTGTAGTGTCTTCAAGCTT GCTTTTTGTGTGGGGATTGGGGAGCTGTCGGGGCGGCTGCCATTTGGTAGCTGTTGAGGGAGTTGAGAGG GAGCGTATTGTGCGGATGAAAGCGGGACGCTTCGAGGCAGACGAAGGAACATCTGTTAGGTGCGGCGTTT CGGGAGGTGTTTTTGGGGTGGCCGGGCATTCTGTGGGAGCGAGGGGACCACTTCCAAAGCCCTGGTGCTG TTGGGGTAGGAGGGCGGCCGGCATCAGCCATGTGGCTGAGTCGCGAGTACAAAATGCCGGCCTCGGACAT GGCGGCGGCGCCTTTGTTACCCCGCCCGGCGGAGGAGCTCAAAATGGCAGCGTCGAGAAAATGTGGCGCA GAGAGAAATGCGAGACAAAGGGGGAAGCGCCGCCCCAGCGGGAACGCCGCCCGGCCGACTCCGCCCGGGC CGGGACTCCTCCCCCGGTAGTCGCCGGCTCCTCCTTTTCTTTTTTCCTGCGTTATATAATTTTGATTCGT TGATCCGGAGCTCTACCGCGGCGTTCCCCCAGCTGGGTTTGCTAGCAGAAGTGTTTCTGAGAAAACCCTT GTTCTGTTATCGCTGACTGTACTGTTTAGGTTCTTACCACTAAAGCTGTTTGGTTCCAAAACGGCCATAT GAGTAACATCGTCGTGATGCTCTTCGGTTCATGTAGCCTTGTTATTGCTGATAGTGAATTGCTAGGCTGG TGGGGAAGATTACAGTAACCACAAGAAGTGGTGTGTGCCAGAATCCCAAATTCTGGCATGTGGGTGACAA GTTTCCGACATGATAAATCCCCGGCTTCCGACATGATAAATCCCAGGCTGTTTACATGACCTAAGTAATG TGTACTTGGGACTACGGGAAATGTTAACTGTGGCTGTTGAGAGAGAGAGAGATTTTCACGAAGGACAGTG CTAGGTTTACCTCTCGAAGTCTGTTTTCAGTGGTTTTTAGCTTGTGCCAATGGATGACAAATCTATACAG AAACCTGGGTATAGCCATTTGAAAATGTGAATAACGTTTTTTTTCATTCCAGGTTTGGTGCACCTCGATT TGGAGGAAGTAGGGCAGGGCCCTTATCTGGAAAGAAGTTTGGAAACCCTGGGGAGAAATTAGTTAAAAAG AAGTGGAATCTTGATGAGCTGCCTAAATTTGAGAAGAATTTTTATCAAGAGCACCCTGATTTGGCTAGGC GCACAGCAGTGAGTAAATTCATGTGGCTTCATCAGGCTGTAACTCGATCGTGGATTCTAGTAAATGAAAT TCTGACAGGTGTTTTGCAAATAACTCAATTTTGGTAGAGTTACATGTTCTGACTTCATAATTGGGAAAGG TGTGACTCACTTTTGGATATAGGTGGCTTTGGGATTTTTACTTAAATTAGGTTGAGTATAACAATAAATT TTTTTTTTCATAATAGGGTGTTCATAGGTGGGTCCAGATTAAAATGAAGGCTACTTTAAACTAGTTACTA AATTATGAAGTTAGGGGCTTATCAATTACGTATTTAGCTAGGGGTGGTTGTCATGAATTTTAAGACTGTT ATAATTTGTTTTGCAGCAAGAGGTGGAAACATACAGAAGAAGCAAGGAAATTACAGTTAGAGGTCACAAC TGCCCGAAGCCAGTTCTAAATTTTTATGAAGCCAATTTCCCTGGTAAGTGCTACTTTTCAGTTCTACCTA CCCGTGTTTTTGTTTCCACCTACCCCCTCTTTTTCTTGGCATCACTAATTTTTACTAAATATCTGTTACT AATTATAGCAAATGTCATGGATGTTATTGCAAGACAGAATTTCACTGAACCCACTGCTATTCAAGCTCAG GGATGGCCAGTTGCTCTAAGTGGATTGGATATGGTTGGAGTGGCACAGACTGGATCTGGGAAAACATTGT CTGTAAGTTTGGGAGAACTCTTGAGTTGATCTGATATATGCAAGAAAATGTAATGGTAATTTAAAAACGA GTATTTTAATGTGATTTCTGTTTGTCCCCACTTTCACCCTAAATAGTATTTGCTTCCTGCCATTGTCCAC ATCAATCATCAGCCATTCCTAGAGAGAGGCGATGGGCCTATTGTAAGTATATATTTTTAACTTTTTATTA GAAGCATAATGTGTAGATTTTAGACTACATAGCTAAAGATGTAATCATTTGTGGTGGTTTTATATAGAGG TTAGCTCACCCTATTCAGCTGGAGCTGTTTTGGGTATTGGACAACACATGAAGAAAGGATCTGCTAGTAT AATAAGTTAGCAGTTTAAAACTAGTATCCAGGTTTGTGCTGAAAGCTGTTTCTCTTTCCTTAGTGTTTGG TGCTGGCACCAACTCGGGAACTGGCCCAACAGGTGCAGCAAGTAGCTGCTGAATATTGTAGAGCATGTCG CTTGAAGTCTACTTGTATCTACGGTGGTGCTCCTAAGGGACCACAAATACGTGATTTGGAGAGAGGTATG TAATGAAAAGGGTTTTATTTGTCATTGGTGCTAAATATCCTAGGTATTGTAGTTACACTTACGTATTTAA TTAAAGGTGTGGAAATCTGTATTGCAACACCTGGAAGACTGATTGACTTTTTAGAGTGTGGAAAAACCAA TCTGAGAAGAACAACCTACCTTGTCCTTGATGAAGCAGATAGAATGCTTGATATGGGCTTTGAACCCCAA ATAAGGAAGATTGTGGATCAAATAAGAGTAAGTGTCCTTTGAAATATGTGATCAAACTGAATTGTGTTTT CACTCTTAAGAGTCTGATACTAATTTTTCCCCCCAAAATCCATTAGCCTGATAGGCAAACTCTAATGTGG AGTGCGACTTGGCCAAAAGAAGTAAGACAGCTTGCTGAAGATTTCCTGAAAGACTATATTCATATAAACA TTGGTGCACTTGAACTGAGTGCAAACCACAACATTCTTCAGATTGTGGATGTGTGTCATGACGTAGAAAA GGATGAAAAGTAAGTTTTATTAACTCTGTTATATTTGCTTCCTAACAACTTTGCTGTAAAATTGAGGGAT CATTGTTTGGTGAGTTGTTTTAGGTTATTTCAGTTGGTGTGATTTCATTTAGTTAGCCTACTAATCCTGA AAATTTCTTGAATCCTTCAAATAATGGCTGTCACCATTTATAGCTTTCCTATAGAAGGAATTCATGTGTC CCCTGGTTGACTTAAGGACCAAGGGTCGAACTGCTCGATAAGTGGATTAGCAGGCGTTTCCTCTTTGACT TCCAGCCATGTAAATTGAACTTAATGTTTTGCTGACCATAAATGTGTGGCCCTAGCAATGGTCTTTTAAA ACTCAGGATTTTTCCTTTCTCTCTCCTATTATTAGACTTATTCGTCTAATGGAAGAGATCATGAGTGAGA AGGAGAATAAAACCATTGTTTTTGTGGAAACCAAAAGAAGATGTGATGAGCTTACCAGAAAAATGAGGAG AGATGGGTATGTGTGAGCTCCTCCATTGAAGCAGATTGATTAAAACAGCTTAGGAAAGGGCAAACTTGGA TCACGAGCAGTGGATTTTTTTCATATCTGATAGTGAATTTAACTTTTTCATTTCTGGCGAAATTAAAGAG ATCTGTGACCAAAAGTGGTCAAGCACTGGAGTCTGAGGTTTTCAATGTGAGTTTAATAACACAACTTGTC TTTTAACTTAGGTGGCCTGCCATGGGTATCCATGGTGACAAGAGTCAACAAGAGCGTGACTGGGTTCTAA ATGGTAAATATTTCAAATGAAGTATTTTTCCCCCTTACTTAACCTAGCTAGAATTCTGCTCAGATAATTG ATCATGTATATGCCTTCCTTTGTAGAATTCAAACATGGAAAAGCTCCTATTCTGATTGCTACAGATGTGG CCTCCAGAGGGCTAGGTTAGTACAAACTCGCATTCATGGCTTGGTTTCCCAGAAGATCTCCATTTAACTT TTTTAAAGAAAGTTTATTGCTTTCTTTAACCTGCATTTTTTCTAAGTTTTTTTTCACATAAAGGTGCTGT CTTTGTGGCAAGGCCTAGGCATGACAATCGGAGGACTCGAGGGGGATGGAGGACTAGTGATCGGCTGGCT GCTTCCAGTCGATTAGAGAGGTGAAAAAGCTGAACGTGTGCCAGTAATCTTCAAAAGGCAGAACATATCA CCTCTGCCCCGTAAACTGTTCTCTCCGAGGGAAAAAATGGAAGTTATCCTCACAGTTCACTGCCGTGGTA TTTCTTCTGTCCCATGCTTTGCATGACTGCCATGGTACAGCCTTGTTTCAAACTGTTCACTGTGATCTGT GGGTCTTTGAGTTTCAGTGAGTTTGCTGAAATGTCGAAGAAGTAGTTCCAAACTTCAATGTTCAATGAAA TTTTTGTTCAAGTTTGAAATGGAGAGAGCAGCTTTAAAAGGTACTAAGCCTTTTACAAATTGGTGAGTAC TGGCACATGAGATCTAGAGCAGGAGCAACTTCTCACACATAGTAAGTGGGAAAAGAAAGTGCTTTGAAAG TTCCTCCCTCACCTACACAGTAGTCGTCATGTCGAGACCTGCCAGAGAGAGACACATTCTCAAGTGAATC CTGGCTTCTTGGAAGCGCTTGCCTAGACGAGACACAGTGCATAAAAACAACTTTTGGGGGACAGGTATGT TTTCTTGCAGCTGCGGTTGTAAGGTCTTGGCAAGACAAGCAGTGTGGCCAGAATTTTGAACTTCTGATGA ATGTGTAATGCAAAGGACCTTGTACATTTTTTTGTTTCAAGGTCCTCAAAATGAGCACATGAAGAGGTTG CTGTGAAACTTTAAGTGGCCCTACTGCGCAGAAGCATTCAGATGTCACTTGATGATCTGTAAGGGAACTT GCTGATTTGGGAATGTGCTTAGGGAACACACATTCCTTTTGACAGGGTCTGTCACTGGGTGGGTGATGAA TTATACAGATGACATGTGCTTTTTTTTCTTTTTTCAACCTCAATGGTATTCCTACAGGAAATGGATAACC ATTTTAACTGTATTTTTTGCAGCCCGTACCTTCTTGGGAATACAATTGTCTAACTTTTTATTTTTGGTCT GGCTGTTGTGGTGTGCAAAACTCCGTACATTGCTATTTTGCCACACTGCAACACCTTACAGATGTGGAAG ATGTGAAATTTGTCATCAATTATGACTACCCTAACTCCTCAGAGGATTATATTCATCGAATTGGAAGAAC TGCTCGCAGTACCAAAACAGGCACAGCATACACTTTCTTTACACCTAATAACATAAAGCAAGTGAGCGAC CTTATCTCTGTGCTTCGTGAAGCTAATCAAGCAATTAATCCCAAGTTGCTTCAGTTGGTCGAAGACAGAG GTTCAGGTAAGGATGACTGATAGGAAATGTTGGTAGTTACGAGTCACATCGTTGTCTACAAATCCATTTA AATGGTATTGGAGGGTGAGTAAAACCTTGAATGTGAAAACTTAAGCTGAAAAATTGTAAAAACATTTCAC GCCTACCATGAATAGATCTGTTTCTTTCTGTCCACAATGATTTGTGTCATAGACATAATTGATCAATTTG CAATTGTTTTCTTGACAGGTCGTTCCAGGGGTAGAGGAGGCATGAAGGATGACCGTCGGGACAGATACTC TGCGGGCAAAAGGGGTGGATTTAATACCTTTAGAGACAGGGAAAATTATGACAGAGGTTACTCTAGCCTG CTTAAAAGAGATTTTGGGGCAAAAACTCAGAATGGTGTTTACAGTGCTGCAAATTACACCAATGGGAGCT TTGGAAGTAATTTTGTGTCTGCTGGTATACAGACCAGTTTTAGGACTGGTAATCCAACAGGGACTTACCA GAATGGTTATGATAGCACTCAGCAATACGGAAGTAATGTTCCAAATATGCACAATGGTATGAACCAACAG GCATATGCATATCCTGCTACTGCAGCTGCACCTATGATTGGTTATCCAATGCCAACAGGATATTCCCAAT AAGACTTTAGAAGTATATGTAAATGTCTGTTTTTCATAATTGCTCTTTATATTGTGTGTTATCTGACAAG ATAGTTATTTAAGAAACATGGGAATTGCAGAAATGACTGCAGTGCAGCAGTAATTATGGTGCACTTTTTC GCTATTTAAGTTGGATATTTCTCTACATTCCTGAAACAATTTTTAGGTTTTTTTTGTACTAGAAAATGCA GGCAGTGTTTTCACAAAAGTAAATGTACAGTGATTTGAAATACAATAAATGAAGGCAATGCATGGCCTTC CAATAAAAAATATTTGAAGACTGAATTAAGTGGAAATTGTACTTTATTTTATATAATGTCATGTAAAACT TTGCTTAAGATGGTCTGGTTTTTTTTTTGTTTTTGTTTGGTTTTTTTTTTCCATGAAAACAAATGACTGT TCCTTTTTATTTAATTTGGGAGGCAGGGGGAATCAGAAGGCCCTTCTTTATAATGAGCTATTCATATTGC AGGAGTCAGAATGAATTGATACAGGTGAATTTTTAGTTACAGGCTAAATTGCATAAAAGCTTTGTCAGCT TCCAGCATCAGGGGAGTCATTTAATAGCCTTTTTCCTTATTTGCTAGTATGGTTAAATGAGAAAATAGTA AAATAGATACAAAGTCATCTATATAGTGTGAGAACGTGGGTGACTTTTTCAAAGTTTATAATTTAAAAAG CTCCAAATAACTGGCTTTTTCAAGAGACTTATACTCATGCTCTTGGCTATACTGTGAATTACTGAAATGT TGAACAAACCTGTGAAAGACATACATTAGCCCTTTAAGATGGCCAGGAGCTAAGCTTGAGTCTCCTTTAC TGAATTTCGTTCTTAGTGCAGGTTACTTGTAGATTCTAGTCTTCACAGGCTCCCTGGGGCTCTTAACTAG TCACACTGGGAGTCATGAATGTCTTTCCAATAATTCAGGGAATTCTAGAGATCCTCAAACTGTAAGGTCT ATTCATACTCAACACAAGGAAAAAACCTCATTAAAATTAATGACTAATCAGGAGGCAACGTAACCAAAAG CACAGTGAATGAAAGTTTTCATGGTAGGTTCAACATGGGTTTATTGCTAGAAAGATCCAGGGGATAGCTT TAGGTTTAACTTCGGCTCACCAACGTAACTTTCTAATCATTTATTTCAGTAATAGCTAGAAGTGGGTCTG AATGTTTTCCCAGAGTCTGATACGTGTTTTTTTTTGCCAGAAGAGAGGTCTTCAGGAGACTTCATTTAAA TTCTGATTATTAAACTGAGGCTTTAATTGATGTTAATGCCTTATGTCAAATGTAAAGTTAGAATTTGCTA GGGCTGGGATAGGGAGTGATATTTCTAGGACTTAGACATTGAAAACTAATTCAGCCTGTAGTAACCTGGA TGGTTTTCAATGGCATGGTTAGTCAAATTCATGGTTTTAAACTTAGAAGCAGCTTTCGGGGGAGAGGGTA GGTTGGAGCATTTATTACATATTTTACTGTTTAATGTCTTAACCGTGGGCCTTTTAATTTGTAAACACTG AAATGATTGTTGGGCTGTGGAAAACATTTACCTATTTACCTTGGAAGTTTTAAAAGACAGTCCACTTTTT AGCATGTGTGTTGTGTCCAGCCTGTGGTCGTCTTAACTAATAAATGTGATTTTTCTCCC Download Select all
Length	8669
OMIM ID	180630
HGNC ID	HGNC:2746
Unigene ID	Hs.279806
Ensembl ID	ENSG00000108654
PharmGKB ID	-

mRNA Information

mRNA ID	NM_004396.3
Exon	join(559..849,2083..2248,2607..2703,2809..2942,3057..3122, 3354..3495,3577..3737,3827..3999,4376..4486,4702..4763, 4856..4915,6152..6376,6599..8669)
mRNA Sequence	>1655 ATAGAGCGGCTCCCAGCGTTCCCTGCGGCGTAGGAGGCGGTCCAGACTATAAAAGCGGCTGCCG GAAAGCGGCCGGCACCTCATTCATTTCTACCGGTCTCTAGTAGTGCAGCTTCGGCTGGTGTCAT CGGTGTCCTTCCTCCGCTGCCGCCCCCGCAAGGCTTCGCCGTCATCGAGGCCATTTCCAGCGAC TTGTCGCACGCTTTTCTATATACTTCGTTCCCCGCCAACCGCAACCATTGACGCCATGTCGGGT TATTCGAGTGACCGAGACCGCGGCCGGGACCGAGGGTTTGGTGCACCTCGATTTGGAGGAAGTA GGGCAGGGCCCTTATCTGGAAAGAAGTTTGGAAACCCTGGGGAGAAATTAGTTAAAAAGAAGTG GAATCTTGATGAGCTGCCTAAATTTGAGAAGAATTTTTATCAAGAGCACCCTGATTTGGCTAGG CGCACAGCACAAGAGGTGGAAACATACAGAAGAAGCAAGGAAATTACAGTTAGAGGTCACAACT GCCCGAAGCCAGTTCTAAATTTTTATGAAGCCAATTTCCCTGCAAATGTCATGGATGTTATTGC AAGACAGAATTTCACTGAACCCACTGCTATTCAAGCTCAGGGATGGCCAGTTGCTCTAAGTGGA TTGGATATGGTTGGAGTGGCACAGACTGGATCTGGGAAAACATTGTCTTATTTGCTTCCTGCCA TTGTCCACATCAATCATCAGCCATTCCTAGAGAGAGGCGATGGGCCTATTTGTTTGGTGCTGGC ACCAACTCGGGAACTGGCCCAACAGGTGCAGCAAGTAGCTGCTGAATATTGTAGAGCATGTCGC TTGAAGTCTACTTGTATCTACGGTGGTGCTCCTAAGGGACCACAAATACGTGATTTGGAGAGAG GTGTGGAAATCTGTATTGCAACACCTGGAAGACTGATTGACTTTTTAGAGTGTGGAAAAACCAA TCTGAGAAGAACAACCTACCTTGTCCTTGATGAAGCAGATAGAATGCTTGATATGGGCTTTGAA CCCCAAATAAGGAAGATTGTGGATCAAATAAGACCTGATAGGCAAACTCTAATGTGGAGTGCGA CTTGGCCAAAAGAAGTAAGACAGCTTGCTGAAGATTTCCTGAAAGACTATATTCATATAAACAT TGGTGCACTTGAACTGAGTGCAAACCACAACATTCTTCAGATTGTGGATGTGTGTCATGACGTA GAAAAGGATGAAAAACTTATTCGTCTAATGGAAGAGATCATGAGTGAGAAGGAGAATAAAACCA TTGTTTTTGTGGAAACCAAAAGAAGATGTGATGAGCTTACCAGAAAAATGAGGAGAGATGGGTG GCCTGCCATGGGTATCCATGGTGACAAGAGTCAACAAGAGCGTGACTGGGTTCTAAATGAATTC AAACATGGAAAAGCTCCTATTCTGATTGCTACAGATGTGGCCTCCAGAGGGCTAGATGTGGAAG ATGTGAAATTTGTCATCAATTATGACTACCCTAACTCCTCAGAGGATTATATTCATCGAATTGG AAGAACTGCTCGCAGTACCAAAACAGGCACAGCATACACTTTCTTTACACCTAATAACATAAAG CAAGTGAGCGACCTTATCTCTGTGCTTCGTGAAGCTAATCAAGCAATTAATCCCAAGTTGCTTC AGTTGGTCGAAGACAGAGGTTCAGGTCGTTCCAGGGGTAGAGGAGGCATGAAGGATGACCGTCG GGACAGATACTCTGCGGGCAAAAGGGGTGGATTTAATACCTTTAGAGACAGGGAAAATTATGAC AGAGGTTACTCTAGCCTGCTTAAAAGAGATTTTGGGGCAAAAACTCAGAATGGTGTTTACAGTG CTGCAAATTACACCAATGGGAGCTTTGGAAGTAATTTTGTGTCTGCTGGTATACAGACCAGTTT TAGGACTGGTAATCCAACAGGGACTTACCAGAATGGTTATGATAGCACTCAGCAATACGGAAGT AATGTTCCAAATATGCACAATGGTATGAACCAACAGGCATATGCATATCCTGCTACTGCAGCTG CACCTATGATTGGTTATCCAATGCCAACAGGATATTCCCAATAAGACTTTAGAAGTATATGTAA ATGTCTGTTTTTCATAATTGCTCTTTATATTGTGTGTTATCTGACAAGATAGTTATTTAAGAAA CATGGGAATTGCAGAAATGACTGCAGTGCAGCAGTAATTATGGTGCACTTTTTCGCTATTTAAG TTGGATATTTCTCTACATTCCTGAAACAATTTTTAGGTTTTTTTTGTACTAGAAAATGCAGGCA GTGTTTTCACAAAAGTAAATGTACAGTGATTTGAAATACAATAAATGAAGGCAATGCATGGCCT TCCAATAAAAAATATTTGAAGACTGAATTAAGTGGAAATTGTACTTTATTTTATATAATGTCAT GTAAAACTTTGCTTAAGATGGTCTGGTTTTTTTTTTGTTTTTGTTTGGTTTTTTTTTTCCATGA AAACAAATGACTGTTCCTTTTTATTTAATTTGGGAGGCAGGGGGAATCAGAAGGCCCTTCTTTA TAATGAGCTATTCATATTGCAGGAGTCAGAATGAATTGATACAGGTGAATTTTTAGTTACAGGC TAAATTGCATAAAAGCTTTGTCAGCTTCCAGCATCAGGGGAGTCATTTAATAGCCTTTTTCCTT ATTTGCTAGTATGGTTAAATGAGAAAATAGTAAAATAGATACAAAGTCATCTATATAGTGTGAG AACGTGGGTGACTTTTTCAAAGTTTATAATTTAAAAAGCTCCAAATAACTGGCTTTTTCAAGAG ACTTATACTCATGCTCTTGGCTATACTGTGAATTACTGAAATGTTGAACAAACCTGTGAAAGAC ATACATTAGCCCTTTAAGATGGCCAGGAGCTAAGCTTGAGTCTCCTTTACTGAATTTCGTTCTT AGTGCAGGTTACTTGTAGATTCTAGTCTTCACAGGCTCCCTGGGGCTCTTAACTAGTCACACTG GGAGTCATGAATGTCTTTCCAATAATTCAGGGAATTCTAGAGATCCTCAAACTGTAAGGTCTAT TCATACTCAACACAAGGAAAAAACCTCATTAAAATTAATGACTAATCAGGAGGCAACGTAACCA AAAGCACAGTGAATGAAAGTTTTCATGGTAGGTTCAACATGGGTTTATTGCTAGAAAGATCCAG GGGATAGCTTTAGGTTTAACTTCGGCTCACCAACGTAACTTTCTAATCATTTATTTCAGTAATA GCTAGAAGTGGGTCTGAATGTTTTCCCAGAGTCTGATACGTGTTTTTTTTTGCCAGAAGAGAGG TCTTCAGGAGACTTCATTTAAATTCTGATTATTAAACTGAGGCTTTAATTGATGTTAATGCCTT ATGTCAAATGTAAAGTTAGAATTTGCTAGGGCTGGGATAGGGAGTGATATTTCTAGGACTTAGA CATTGAAAACTAATTCAGCCTGTAGTAACCTGGATGGTTTTCAATGGCATGGTTAGTCAAATTC ATGGTTTTAAACTTAGAAGCAGCTTTCGGGGGAGAGGGTAGGTTGGAGCATTTATTACATATTT TACTGTTTAATGTCTTAACCGTGGGCCTTTTAATTTGTAAACACTGAAATGATTGTTGGGCTGT GGAAAACATTTACCTATTTACCTTGGAAGTTTTAAAAGACAGTCCACTTTTTAGCATGTGTGTT GTGTCCAGCCTGTGGTCGTCTTAACTAATAAATGTGATTTTTCTCCCAAAAAAAAAA Download Select all
Length	3769

CDS Information

Location	join(806..849,2083..2248,2607..2703,2809..2942,3057..3122, 3354..3495,3577..3737,3827..3999,4376..4486,4702..4763, 4856..4915,6599..7002)
CDS Sequence	>gi\|221139768:248-2092 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box helicase 5 (DDX5), mRNA ATGTCGGGTTATTCGAGTGACCGAGACCGCGGCCGGGACCGAGGGTTTGGTGCACCTCGATTTGGAGGAA GTAGGGCAGGGCCCTTATCTGGAAAGAAGTTTGGAAACCCTGGGGAGAAATTAGTTAAAAAGAAGTGGAA TCTTGATGAGCTGCCTAAATTTGAGAAGAATTTTTATCAAGAGCACCCTGATTTGGCTAGGCGCACAGCA CAAGAGGTGGAAACATACAGAAGAAGCAAGGAAATTACAGTTAGAGGTCACAACTGCCCGAAGCCAGTTC TAAATTTTTATGAAGCCAATTTCCCTGCAAATGTCATGGATGTTATTGCAAGACAGAATTTCACTGAACC CACTGCTATTCAAGCTCAGGGATGGCCAGTTGCTCTAAGTGGATTGGATATGGTTGGAGTGGCACAGACT GGATCTGGGAAAACATTGTCTTATTTGCTTCCTGCCATTGTCCACATCAATCATCAGCCATTCCTAGAGA GAGGCGATGGGCCTATTTGTTTGGTGCTGGCACCAACTCGGGAACTGGCCCAACAGGTGCAGCAAGTAGC TGCTGAATATTGTAGAGCATGTCGCTTGAAGTCTACTTGTATCTACGGTGGTGCTCCTAAGGGACCACAA ATACGTGATTTGGAGAGAGGTGTGGAAATCTGTATTGCAACACCTGGAAGACTGATTGACTTTTTAGAGT GTGGAAAAACCAATCTGAGAAGAACAACCTACCTTGTCCTTGATGAAGCAGATAGAATGCTTGATATGGG CTTTGAACCCCAAATAAGGAAGATTGTGGATCAAATAAGACCTGATAGGCAAACTCTAATGTGGAGTGCG ACTTGGCCAAAAGAAGTAAGACAGCTTGCTGAAGATTTCCTGAAAGACTATATTCATATAAACATTGGTG CACTTGAACTGAGTGCAAACCACAACATTCTTCAGATTGTGGATGTGTGTCATGACGTAGAAAAGGATGA AAAACTTATTCGTCTAATGGAAGAGATCATGAGTGAGAAGGAGAATAAAACCATTGTTTTTGTGGAAACC AAAAGAAGATGTGATGAGCTTACCAGAAAAATGAGGAGAGATGGGTGGCCTGCCATGGGTATCCATGGTG ACAAGAGTCAACAAGAGCGTGACTGGGTTCTAAATGAATTCAAACATGGAAAAGCTCCTATTCTGATTGC TACAGATGTGGCCTCCAGAGGGCTAGATGTGGAAGATGTGAAATTTGTCATCAATTATGACTACCCTAAC TCCTCAGAGGATTATATTCATCGAATTGGAAGAACTGCTCGCAGTACCAAAACAGGCACAGCATACACTT TCTTTACACCTAATAACATAAAGCAAGTGAGCGACCTTATCTCTGTGCTTCGTGAAGCTAATCAAGCAAT TAATCCCAAGTTGCTTCAGTTGGTCGAAGACAGAGGTTCAGGTCGTTCCAGGGGTAGAGGAGGCATGAAG GATGACCGTCGGGACAGATACTCTGCGGGCAAAAGGGGTGGATTTAATACCTTTAGAGACAGGGAAAATT ATGACAGAGGTTACTCTAGCCTGCTTAAAAGAGATTTTGGGGCAAAAACTCAGAATGGTGTTTACAGTGC TGCAAATTACACCAATGGGAGCTTTGGAAGTAATTTTGTGTCTGCTGGTATACAGACCAGTTTTAGGACT GGTAATCCAACAGGGACTTACCAGAATGGTTATGATAGCACTCAGCAATACGGAAGTAATGTTCCAAATA TGCACAATGGTATGAACCAACAGGCATATGCATATCCTGCTACTGCAGCTGCACCTATGATTGGTTATCC AATGCCAACAGGATATTCCCAATAA Download Select all
CCDS ID	-

Protein Information

Protein ID	NP_004387.1
Protein Name	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
Molecular Wt. (Da)	69017
Protein Sequence	>1655 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPD LARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVA LSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCR ACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDM GFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVC HDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVL NEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPN NIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRE NYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQ YGSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGYSQ Download Select all
Length	614
Uniprot ID	Q92858
Ensembl Protein ID	ENSP00000302216

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	557
R	Methylation	502
Y	Phosphorylation	297;-
S	Phosphorylation	480
T	Phosphorylation	507
S	Phosphorylation	520
S	Phosphorylation	30
K	Acetylation	32
K	Acetylation	33
K	Acetylation	40
S	Phosphorylation	6
T	Phosphorylation	224
S	Phosphorylation	498
S	Phosphorylation	519

Enzyme Information

EC	3.6.4.13
Name	RNA helicase CSFV NS3 helicase DBP2 DbpA DDX17 DDX25 DDX3 DDX3X DDX3Y DDX4 DDX5 DEAD-box protein DED1 DEAD-box RNA helicase DEAH-box protein 2 DEAH-box RNA helicase DED1 Dex(H/D) RNA helicase EhDEAD1 EhDEAD1 RNA helicase eIF4A helicase KOKV helicase Mtr4p nonstructural protein 3 helicase NPH-II RHA RNA helicase A RNA helicase DDX3 RNA helicase Hera RNA-dependent ATPase TGBp1 NTPase/helicase domain VRH1 GRTH/DDX25
Class	Hydrolases; Acting on acid anhydrides; Acting on acid anhydrides to facilitate cellular and subcellular movement
Sysname	ATP phosphohydrolase (RNA helix unwinding)
Substrate	ATP [CPD:C00002]; H2O
Product	ADP [CPD:C00008]; phosphate
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
801	CALM1	241	NP_008819.1	in vitro	7525583
2091	FBL	617	NP_001427.2	in vivo;yeast 2-hybrid	10837141
2099	ESR1	589	NP_000116.2	in vivo;yeast 2-hybrid	12738788
7157	TP53	1859	NP_000537.3	in vitro;in vivo	15660129
8202	NCOA3	3570	NP_858045.1	yeast 2-hybrid	11250900
8648	NCOA1	4070	NP_003734.3	in vitro;yeast 2-hybrid	11250900
10499	NCOA2	9066	NP_006531.1	in vitro;yeast 2-hybrid	11250900

Pathway Information

Pathway Name	Pathway ID
Proteoglycans in cancer	hsa05205
Spliceosome	hsa03040
Transcriptional misregulation in cancer	hsa05202

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00268	96-301	DEADc
cl21455	96-301	P-loop_NTPase superfamily
cd00079	312-444	HELICc
cl21455	312-444	P-loop_NTPase superfamily
pfam00270	118-289	DEAD
cd00046	133-282	DEXDc
pfam00271	359-434	Helicase_C
smart00490	355-434	HELICc
pfam08061	551-583	P68HR
cl06891	551-583	P68HR superfamily
pfam08061	498-532	P68HR
cl06891	498-532	P68HR superfamily
cd09639	245-434	Cas3_I
PTZ00110	6-507	PTZ00110
COG0513	68-530	SrmB
PRK11776	96-448	PRK11776
PRK11192	95-441	PRK11192
PRK10590	103-461	PRK10590
PLN00206	69-472	PLN00206
PRK11634	96-444	PRK11634
PRK04837	99-444	PRK04837
PRK01297	96-444	PRK01297
PRK04537	91-444	PRK04537
PTZ00424	93-456	PTZ00424
smart00487	109-316	DEXDc
COG0514	129-457	RecQ
TIGR01389	129-450	recQ
TIGR00614	127-476	recQ_fam
COG1201	111-431	Lhr
COG1061	137-439	SSL2
COG1111	289-471	MPH1
PRK11057	128-450	PRK11057
COG1205	121-439	YprA
PRK13766	318-437	PRK13766
COG1202	39-406	COG1202
TIGR03817	86-195	DECH_helic
TIGR01587	245-437	cas3_core
PLN03137	129-458	PLN03137
COG1203	242-434	Cas3
TIGR00631	303-434	uvrb
COG1204	126-398	BRR2
COG0556	305-434	UvrB
COG0553	328-432	HepA
TIGR04121	116-185	DEXH_lig_assoc
COG1199	138-414	DinG
TIGR00580	371-455	mfd

Ontology Information

HPRD ID	3270
Molecular Class	RNA binding protein
Molecular Function	Transcription factor activity (GO:0003700)
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO