Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DHX32 | 55760 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 10 | FLJ10889, FLJ10694, DHLP1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19161603 | 2009 | Cell line : - Source : Xiamen Zhongshan Hospital, Xiamen University in Xiamen Sample Type : CRC tumor and normal tissue No. of Sample : 34 pairs of specimens (tumor tissues and their adjacent normal tissues) and 14 tumor tissues Stage : - | Real time RT-PCR | Up-regulation | - | DHX32 may play an important role in the development of colorectal cancer and could serve as a novel biomarker for colorectal cancer after additional investigation. DHX32 showed higher expression in colorectal cancer tissues than their adjacent tissues, and this result was confirmed by real time RT-PCR. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | DEAH-boxes |
| Description | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. | Chromosome | 10 |
| Location | 10q26.11-q |
| Start | 125836340 |
| End | 125881315 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 44976 |
| OMIM ID | 607960 |
| HGNC ID | HGNC:16717 |
| Unigene ID | Hs.370292 |
| Ensembl ID | ENSG00000089876 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_016567.3 |
|---|---|
| Exon | complement(join(<27621..28191,39986..40061)) | mRNA Sequence | Download Select all |
| Length | 3070 |
CDS Information
| Location | complement(join(<28073..28191,39986..40061)) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS7649.1 |
Protein Information
| Protein ID | NP_060650.2 |
|---|---|
| Protein Name | DEAH (Asp-Glu-Ala-His) box polypeptide 32 |
| Molecular Wt. (Da) | 84288 |
| Protein Sequence | Download Select all |
| Length | 743 |
| Uniprot ID | P08865 |
| Ensembl Protein ID | ENSP00000346067 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 718 |
| S | Phosphorylation | 191 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00046 | 79-215 | DEXDc |
| cl21455 | 79-215 | P-loop_NTPase superfamily |
| pfam04408 | 458-548 | HA2 |
| cl04503 | 458-548 | HA2 superfamily |
| smart00847 | 464-548 | HA2 |
| pfam07717 | 589-696 | OB_NTP_bind |
| cl06657 | 589-696 | OB_NTP_bind superfamily |
| COG1643 | 12-679 | HrpA |
| TIGR01967 | 60-687 | DEAH_box_HrpA |
| PRK11131 | 60-687 | PRK11131 |
| TIGR01970 | 62-516 | DEAH_box_HrpB |
| PRK11664 | 127-515 | PRK11664 |
| smart00487 | 78-191 | DEXDc |
Ontology Information
| HPRD ID | 1047 |
|---|---|
| Molecular Class | ATPase |
| Molecular Function | Signal transducer activity (GO:0004871) |
| Biological Process | Cell growth and/or maintenance (GO:0008151); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.