Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DLEC1 | 9940 | deleted in lung and esophageal cancer 1 | 3 | DLC1, CFAP81 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21443130 | 2010 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 50 Stage : - | Methylation-specific PCR,immunohistochemistry | Hypermethylation | - | Epigenetic inactivation of DLEC1 was crucial in gastric and colorectal carcinogenesis. DLEC1 methylation in serum may be a promise biomarker for GAC and CRAC early diagnosis. |
| 25640947 | 2015 | Cell line : HT29,SW48, HCT116 , HEK293 Source : ATCC Sample Type : - No. of Sample : - Stage : - | Methylation-specificPCR,bisulfite genomic sequencing, and methylated DNA immunoprecipitation assay | Hypermethylation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney. [provided by RefSeq, Jul 2008 | Chromosome | 3 |
| Location | 3p21.3 |
| Start | 38080497 |
| End | 38164228 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 83732 |
| OMIM ID | 604050 |
| HGNC ID | HGNC:2899 |
| Unigene ID | Hs.714499 |
| Ensembl ID | ENSG00000008226 |
| PharmGKB ID | PA27353 |
Protein Information
| Protein ID | NP_031361.2 |
|---|---|
| Protein Name | deleted in lung and esophageal cancer 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1755 |
| Uniprot ID | Q9Y5K1 |
| Ensembl Protein ID | ENSP00000316034 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 85;- |
| S | Phosphorylation | 85;- |
| S | Phosphorylation | 85;- |
| S | Phosphorylation | 85;- |
| S | Phosphorylation | 85;- |
| S | Phosphorylation | 86;- |
| S | Phosphorylation | 86;- |
| S | Phosphorylation | 86;- |
| S | Phosphorylation | 86;- |
| S | Phosphorylation | 86;- |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 9720 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Auxiliary transport protein activity (GO:0015457) |
| Biological Process | Transport (GO:0006810) |
Drug Information
No matching records could be found.