Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
EBAG9 9166 estrogen receptor binding site associated, antigen, 9  8EB9, RCAS1 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24652591   2014Cell line : -

Source : -

Sample Type : CRC tumor

No. of Sample : -

Stage : -

Tissue microarray and immunohistochemistryUp-regulation-RCAS1 might be a supplementary serological marker for CRC.

RCAS1 is not only a supplementary serological biomarker for CRC diagnosis but also useful for monitoring tumor recurrence.

RCAS1 levels in colorectal cancer were significantly higher than those in colorectal polyps and normal colon tissues.


Gene Details



Chromosome 8 - NC_000008.11 (109539700..109565996)

View Larger Image
   
Gene Type protein coding
Gene Family
Description This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10.  
Chromosome 8
Location 8q23
Start 109539700  
End 109565996  
Strand +  
Gene Sequence

   Download   Select all

Length 26297  
OMIM ID 605772   
HGNC ID HGNC:3123   
Unigene ID Hs.409368   
Ensembl ID ENSG00000147654   
PharmGKB ID -   

mRNA Information


mRNA ID NM_198120.2
Exon join(1..220,11111..11208,14166..14244,15030..15188, 17236..17343,21139..21230,24740..26297)  
mRNA Sequence

   Download   Select all

Length 2208  



CDS Information


   
Location join(11126..11208,14166..14244,15030..15188,17236..17343, 21139..21230,24740..24860)
CDS Sequence

   Download   Select all

CCDS ID CCDS6313.1



Protein Information


      
Protein IDNP_001265867.1
Protein Nameestrogen receptor binding site associated, antigen, 9
Molecular Wt. (Da)24246
Protein Sequence

   Download   Select all

Length 213  
Uniprot IDQ9H160
Ensembl Protein ID ENSP00000307183  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation36
TPhosphorylation41
YPhosphorylation48
SPhosphorylation36
TPhosphorylation41
YPhosphorylation48
YPhosphorylation94;-
YPhosphorylation94;-
YPhosphorylation94;-
YPhosphorylation94;-
SPhosphorylation86
SPhosphorylation86

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
23557SNAPIN6111NP_036569.1in vitro;in vivo;yeast 2-hybrid15635093   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam07946160-203  DUF1682
cl20352160-203  DUF1682 superfamily
pfam04111139-206  APG6


Ontology Information


   
HPRD ID930
Molecular ClassMembrane bound ligand
Molecular FunctionChemokine activity (GO:0008009)
Biological ProcessImmune response (GO:0006955)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO