Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| EIF3H | 8667 | eukaryotic translation initiation factor 3, subunit H | 8 | eIF3-gamma, eIF3-p40, eIF3h |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20862326 | 2010 | Cell line : - Source : The National Study of Colorectal Cancer Genetics (NSCCG) Sample Type : Population based case control study No. of Sample : 1,964 CRC cases and 2,081 control Stage : - | SNP,Resequencing,Genotyping,Luciferase assay,Chromosome conformation capture assay | Polymorhpism | - | Increased expression of EIF3H gene increases CRC growth and invasiveness thereby providing a biological mechanism for the 8q23.3 association. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 8 |
| Location | 8q24.11 |
| Start | 117657055 |
| End | 117768258 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 111204 |
| OMIM ID | 603912 |
| HGNC ID | HGNC:3273 |
| Unigene ID | Hs.492599 |
| Ensembl ID | ENSG00000147677 |
| PharmGKB ID | PA162384854 |
Protein Information
| Protein ID | NP_003747.1 |
|---|---|
| Protein Name | eukaryotic translation initiation factor 3, subunit H |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 352 |
| Uniprot ID | P60468 |
| Ensembl Protein ID | ENSP00000223641 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 183;- |
| T | Phosphorylation | 8 |
| S | Phosphorylation | 10 |
| T | Phosphorylation | 11 |
| S | Phosphorylation | 31 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 11007 | CCDC85B | 16101 | NP_006839.2 | yeast 2-hybrid | 16189514 |
| 51225 | ABI3 | 5900 | NP_057512.1 | yeast 2-hybrid | 16189514 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Measles | hsa05162 |
| RNA transport | hsa03013 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd08065 | 37-300 | MPN_eIF3h |
| cl13996 | 37-300 | MPN superfamily |
| smart00232 | 38-172 | JAB_MPN |
| cd08057 | 39-204 | MPN_euk_non_mb |
| pfam01398 | 34-146 | JAB |
| cd08064 | 44-260 | MPN_eIF3f |
| cd08069 | 37-172 | MPN_RPN11_CSN5 |
| cd08062 | 37-122 | MPN_RPN7_8 |
| cd08058 | 47-170 | MPN_euk_mb |
| cd07767 | 47-167 | MPN |
| cd06613 | 89-131 | STKc_MAP4K3_like |
| cl21453 | 89-131 | PKc_like superfamily |
| PLN03246 | 38-123 | PLN03246 |
Ontology Information
| HPRD ID | 5114 |
|---|---|
| Molecular Class | Translation regulatory protein |
| Molecular Function | Serine-type peptidase activity (GO:0008236) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.