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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| EIF5A | 1984 | eukaryotic translation initiation factor 5A | 17 | EIF5A1, EIF-5A, MGC99547, MGC104255 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23322277 | 2013 | Cell line : - Source : - Sample Type : CRC tumor and adjacent normal tissues No. of Sample : 39 CRC tumors and 20 adjecent tissue Stage : - | mRNA PCR arrays | Up-regulation | - | High CK20, MAP3K8 and EIF5A expression levels were significant prognostic factors for poor overall survival in CRC patients. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 17 |
| Location | 17p13-p12 |
| Start | 7210318 |
| End | 7215782 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 5465 |
| OMIM ID | 600187 |
| HGNC ID | HGNC:3300 |
| Unigene ID | Hs.104825 |
| Ensembl ID | ENSG00000132507 |
| PharmGKB ID | PA27726 |
mRNA Information
| mRNA ID | NM_001143760.1 |
|---|---|
| Exon | join(1..117,2617..2802,4020..4124,4352..4483,4580..4653, 4824..5465) | mRNA Sequence | Download Select all |
| Length | 1256 |
Protein Information
| Protein ID | NP_001137232.1 |
|---|---|
| Protein Name | eukaryotic translation initiation factor 5A |
| Molecular Wt. (Da) | 20039 |
| Protein Sequence | Download Select all |
| Length | 184 |
| Uniprot ID | P63151 |
| Ensembl Protein ID | ENSP00000325074 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| K | Acetylation | 47 |
| K | Alkylation | 50 |
| S | Phosphorylation | 46 |
| K | Acetylation | 27 |
| T | Phosphorylation | 9 |
| S | Phosphorylation | 44 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 7052 | TGM2 | 1825 | NP_004604.2 | in vitro;in vivo | 9442029 |
| 83475 | DOHH | 14627 | NP_112594.1 | in vitro | 17213197 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd04468 | 84-152 | S1_eIF5A |
| cl09927 | 84-152 | S1_like superfamily |
| pfam01287 | 83-150 | eIF-5a |
| PLN03107 | 1-150 | PLN03107 |
| PTZ00328 | 3-154 | PTZ00328 |
| TIGR00037 | 14-150 | eIF_5A |
| COG0231 | 17-150 | Efp |
| PRK03999 | 25-94 | PRK03999 |
| TIGR00038 | 25-90 | efp |
Ontology Information
| HPRD ID | 234 |
|---|---|
| Molecular Class | Translation Factor |
| Molecular Function | Protein serine/threonine phosphatase activity (GO:0004722) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.