Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18695888 | 2008 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 205 Stage : - | real time RT-PCR,Immunohistochemistry,Methylation-Specific PCR | Up-regulation | - | Overexpression of the EphA4 gene and reduced expression of the EphB2 gene may thus be a useful predictor of liver metastasis in patients with colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | EPH receptors, "Sterile alpha motif (SAM) domain containing", "Fibronectin type III domain containing" |
| Description | This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] | Chromosome | 2 |
| Location | 2q36.3 |
| Start | 222282747 |
| End | 222437010 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 154264 |
| OMIM ID | 602188 |
| HGNC ID | HGNC:3388 |
| Unigene ID | Hs.371218 |
| Ensembl ID | ENSG00000116106 |
| PharmGKB ID | PA27820 |
mRNA Information
| mRNA ID | NM_001304536.1 |
|---|---|
| Exon | join(1..242,1922..2045,5418..5485,9809..10472, 73031..73186,91513..91851,116213..116337,117431..117590, 118545..118656,128022..128080,130597..130710, 131189..131374,137081..137142,137595..137804, 139912..140061,144052..144245,147584..147739, 148061..148994,153651..156176) | mRNA Sequence | Download Select all |
| Length | 6597 |
Protein Information
| Protein ID | NP_001291465.1 |
|---|---|
| Protein Name | EPH receptor A4 |
| Molecular Wt. (Da) | 107789 |
| Protein Sequence | Download Select all |
| Length | 986 |
| Uniprot ID | P28482 |
| Ensembl Protein ID | ENSP00000215832 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 596 |
| Y | Phosphorylation | 602 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1942 | EFNA1 | 1858 | NP_004419.2 | in vitro | 8755474 |
| 1944 | EFNA3 | 3225 | NP_004943.1 | in vivo | 12496762 |
| 1945 | EFNA4 | 3224 | NP_872631.1 | in vivo | 10366629 |
| 1948 | EFNB2 | 2754 | NP_004084.1 | in vivo | 12761826 |
| 2260 | FGFR1 | 634 | NP_000595.1 | in vivo;yeast 2-hybrid | 16365308 |
| 2261 | FGFR3 | 624 | NP_000133.1 | in vivo;yeast 2-hybrid | 16365308 |
| 2263 | FGFR2 | 1492 | NP_075261.1 | in vivo;yeast 2-hybrid | 16365308 |
| 2534 | FYN | 655 | NP_002028.1 | in vivo | 12084815 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Axon guidance | hsa04360 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05066 | 616-882 | PTKc_EphR_A |
| cl21453 | 616-882 | PKc_like superfamily |
| cd10482 | 30-203 | EphR_LBD_A4 |
| cl02704 | 30-203 | EphR_LBD superfamily |
| cd09545 | 911-981 | SAM_EPH-A4 |
| cl15755 | 911-981 | SAM_superfamily superfamily |
| cd00063 | 441-532 | FN3 |
| cl21522 | 441-532 | FN3 superfamily |
| cd00063 | 329-436 | FN3 |
| cl21522 | 329-436 | FN3 superfamily |
| cd05033 | 616-882 | PTKc_EphR |
| cd05065 | 616-882 | PTKc_EphR_B |
| cd05063 | 615-882 | PTKc_EphR_A2 |
| cd05064 | 615-882 | PTKc_EphR_A10 |
| cd00192 | 625-879 | PTKc |
| cd10473 | 30-203 | EphR_LBD_A |
| pfam01404 | 30-204 | Ephrin_lbd |
| smart00615 | 30-203 | EPH_lbd |
| cd05034 | 625-879 | PTKc_Src_like |
| cd10483 | 30-203 | EphR_LBD_A5 |
| cd10481 | 30-203 | EphR_LBD_A3 |
| cd10485 | 28-204 | EphR_LBD_A7 |
| cd05068 | 615-871 | PTKc_Frk_like |
| cd10487 | 30-203 | EphR_LBD_A10 |
| cd05041 | 627-879 | PTKc_Fes_like |
| cd10486 | 30-203 | EphR_LBD_A8 |
| cd10484 | 30-203 | EphR_LBD_A6 |
| cd05060 | 627-878 | PTKc_Syk_like |
| cd10472 | 32-203 | EphR_LBD_B |
| cd05039 | 621-878 | PTKc_Csk_like |
| cd05148 | 623-879 | PTKc_Srm_Brk |
| cd05059 | 616-871 | PTKc_Tec_like |
| cd10478 | 30-203 | EphR_LBD_B3 |
| cd05056 | 615-878 | PTKc_FAK |
| cd05032 | 615-879 | PTKc_InsR_like |
| cd10476 | 32-203 | EphR_LBD_B1 |
| cd13999 | 627-878 | STKc_MAP3K-like |
| cd05067 | 615-879 | PTKc_Lck_Blk |
| cd10319 | 31-203 | EphR_LBD |
| cd05072 | 613-879 | PTKc_Lyn |
| cd05049 | 615-880 | PTKc_Trk |
| cd05044 | 625-878 | PTKc_c-ros |
| cd05048 | 615-878 | PTKc_Ror |
| cd05040 | 625-878 | PTKc_Ack_like |
| cd14203 | 625-879 | PTKc_Src_Fyn_like |
| cd05051 | 622-874 | PTKc_DDR |
| cd10477 | 30-203 | EphR_LBD_B2 |
| cd05052 | 615-882 | PTKc_Abl |
| cd05084 | 627-874 | PTKc_Fes |
| cd05057 | 621-885 | PTKc_EGFR_like |
| cd05036 | 614-880 | PTKc_ALK_LTK |
| cd05050 | 615-880 | PTKc_Musk |
| cd05112 | 616-878 | PTKc_Itk |
| cd05073 | 613-879 | PTKc_Hck |
| cd05070 | 615-879 | PTKc_Fyn |
| cd05085 | 625-874 | PTKc_Fer |
| cd05038 | 621-881 | PTKc_Jak_rpt2 |
| cd10480 | 30-204 | EphR_LBD_A2 |
| cd05069 | 613-879 | PTKc_Yes |
| cd05071 | 613-871 | PTKc_Src |
| cd05113 | 616-875 | PTKc_Btk_Bmx |
| cd05115 | 627-878 | PTKc_Zap-70 |
| cd05083 | 625-880 | PTKc_Chk |
| cd05114 | 616-882 | PTKc_Tec_Rlk |
| cd05053 | 615-882 | PTKc_FGFR |
| cd05092 | 627-878 | PTKc_TrkA |
| cd05061 | 615-878 | PTKc_InsR |
| cd05095 | 627-878 | PTKc_DDR2 |
| cd05058 | 625-875 | PTKc_Met_Ron |
| cd05091 | 614-878 | PTKc_Ror2 |
| cd05082 | 621-881 | PTKc_Csk |
| cd05045 | 621-884 | PTKc_RET |
| cd05090 | 615-874 | PTKc_Ror1 |
| cd05109 | 621-886 | PTKc_HER2 |
| cd10479 | 30-203 | EphR_LBD_A1 |
| cd05116 | 627-871 | PTKc_Syk |
| cd10475 | 30-203 | EphR_LBD_B6 |
| cd05108 | 622-886 | PTKc_EGFR |
| cd05097 | 621-878 | PTKc_DDR_like |
| cd05035 | 621-882 | PTKc_TAM |
| cd05046 | 625-880 | PTK_CCK4 |
| cd05093 | 621-883 | PTKc_TrkB |
| cd05075 | 621-884 | PTKc_Axl |
| cd05096 | 619-878 | PTKc_DDR1 |
| cd10474 | 30-203 | EphR_LBD_B4 |
| cd14204 | 616-882 | PTKc_Mer |
| cd05110 | 621-885 | PTKc_HER4 |
| cd05099 | 625-882 | PTKc_FGFR4 |
| cd05047 | 626-881 | PTKc_Tie |
| cd05101 | 602-882 | PTKc_FGFR2 |
| cd05094 | 621-881 | PTKc_TrkC |
| cd05055 | 600-882 | PTKc_PDGFR |
| cd05074 | 625-881 | PTKc_Tyro3 |
| cd05089 | 621-882 | PTKc_Tie1 |
| cd05054 | 611-881 | PTKc_VEGFR |
| cd05062 | 615-876 | PTKc_IGF-1R |
| cd05111 | 625-885 | PTK_HER3 |
| cd05088 | 616-882 | PTKc_Tie2 |
| cd05100 | 615-882 | PTKc_FGFR3 |
| cd05098 | 625-882 | PTKc_FGFR1 |
| cd14205 | 621-881 | PTKc_Jak2_rpt2 |
| cd00180 | 627-878 | PKc |
| cd05103 | 621-883 | PTKc_VEGFR2 |
| cd05079 | 627-882 | PTKc_Jak1_rpt2 |
| cd05043 | 630-878 | PTK_Ryk |
| cd14207 | 611-881 | PTKc_VEGFR1 |
| cd05081 | 621-881 | PTKc_Jak3_rpt2 |
| cd05102 | 615-883 | PTKc_VEGFR3 |
| cd05106 | 600-883 | PTKc_CSF-1R |
| cd14058 | 627-883 | STKc_TAK1 |
| cd05080 | 621-878 | PTKc_Tyk2_rpt2 |
| cd14061 | 626-881 | STKc_MLK |
| cd05107 | 600-882 | PTKc_PDGFR_beta |
| cd14014 | 622-870 | STKc_PknB_like |
| cd14062 | 627-879 | STKc_Raf |
| cd05104 | 600-882 | PTKc_Kit |
| cd14059 | 627-879 | STKc_MAP3K12_13 |
| cd05105 | 600-882 | PTKc_PDGFR_alpha |
| cd13978 | 627-872 | STKc_RIP |
| cd14150 | 621-883 | STKc_A-Raf |
| cd06606 | 625-869 | STKc_MAPKKK |
| cd05122 | 622-869 | PKc_STE |
| cd14066 | 627-881 | STKc_IRAK |
| cd14151 | 615-884 | STKc_B-Raf |
| cd08215 | 622-877 | STKc_Nek |
| cd14154 | 627-881 | STKc_LIMK |
| cd14145 | 615-881 | STKc_MLK1 |
| cd14149 | 615-881 | STKc_C-Raf |
| cd14003 | 622-876 | STKc_AMPK-like |
| cd06627 | 627-869 | STKc_Cdc7_like |
| cd14060 | 628-881 | STKc_MLTK |
| cd14146 | 626-878 | STKc_MLK4 |
| cd05117 | 622-846 | STKc_CAMK |
| cd14148 | 626-881 | STKc_MLK2 |
| cd05037 | 628-878 | PTK_Jak_rpt1 |
| cd14147 | 621-881 | STKc_MLK3 |
| cd14221 | 627-884 | STKc_LIMK1 |
| cd14065 | 627-878 | PKc_LIMK_like |
| cd09488 | 912-972 | SAM_EPH-R |
| cd14064 | 627-879 | PKc_TNNI3K |
| cd14222 | 627-881 | STKc_LIMK2 |
| cd05042 | 625-861 | PTKc_Aatyk |
| cd05086 | 627-861 | PTKc_Aatyk2 |
| cd14206 | 627-874 | PTKc_Aatyk3 |
| cd14009 | 627-860 | STKc_ATG1_ULK_like |
| cd05087 | 625-869 | PTKc_Aatyk1 |
| cd06612 | 623-869 | STKc_MST1_2 |
| cd14080 | 623-876 | STKc_TSSK-like |
| cd06614 | 625-869 | STKc_PAK |
| cd06632 | 625-876 | STKc_MEKK1_plant |
| cd13992 | 641-881 | PK_GC |
| cd07840 | 622-816 | STKc_CDK9_like |
| cd14008 | 627-849 | STKc_LKB1_CaMKK |
| cd06623 | 625-869 | PKc_MAPKK_plant_like |
| cd06629 | 625-869 | STKc_Bck1_like |
| pfam14575 | 562-618 | EphA2_TM |
| cl22928 | 562-618 | EphA2_TM superfamily |
| cd14664 | 627-879 | STK_BAK1_like |
| cd08222 | 623-876 | STKc_Nek11 |
| cd06640 | 622-869 | STKc_MST4 |
| cd14099 | 622-876 | STKc_PLK |
| cd14025 | 627-874 | STKc_RIP4_like |
| cd08225 | 625-875 | STKc_Nek5 |
| cd14063 | 621-883 | PK_KSR |
| cd06609 | 622-846 | STKc_MST3_like |
| cd14007 | 622-876 | STKc_Aurora |
| cd14155 | 627-883 | PKc_TESK |
| cd14026 | 630-883 | STKc_RIP2 |
| cd05118 | 622-839 | STKc_CMGC |
| cd07834 | 622-818 | STKc_MAPK |
| cd06605 | 625-877 | PKc_MAPKK |
| cd09548 | 907-976 | SAM_EPH-A7 |
| cd08529 | 623-885 | STKc_FA2-like |
| cd14043 | 650-874 | PK_GC-2D |
| cd06628 | 626-869 | STKc_Byr2_like |
| cd09554 | 911-975 | SAM_EPH-B4 |
| cd13979 | 626-869 | STKc_Mos |
| cd05076 | 627-878 | PTK_Tyk2_rpt1 |
| cd06620 | 615-877 | PKc_Byr1_like |
| cd09551 | 908-975 | SAM_EPH-B1 |
| cd14002 | 626-848 | STKc_STK36 |
| cd05078 | 627-879 | PTK_Jak2_rpt1 |
| cd06641 | 622-875 | STKc_MST3 |
| cd07829 | 622-818 | STKc_CDK_like |
| cd14052 | 624-877 | PTKc_Wee1_fungi |
| cd14158 | 627-819 | STKc_IRAK4 |
| cd14663 | 622-845 | STKc_SnRK3 |
| cd14069 | 622-827 | STKc_Chk1 |
| cd14081 | 622-865 | STKc_BRSK1_2 |
| cd14121 | 624-825 | STKc_ULK3 |
| cd06611 | 627-874 | STKc_SLK_like |
| cd14027 | 650-876 | STKc_RIP1 |
| cd08530 | 622-876 | STKc_CNK2-like |
| cd14202 | 626-871 | STKc_ULK1 |
| cd06648 | 627-846 | STKc_PAK_II |
| cd05580 | 621-848 | STKc_PKA_like |
| cd14054 | 626-817 | STKc_BMPR2_AMHR2 |
| cd14084 | 623-835 | STKc_Chk2 |
| cd14000 | 651-878 | STKc_LRRK |
| cd14053 | 625-819 | STKc_ACVR2 |
| cd06610 | 622-869 | STKc_OSR1_SPAK |
| cd14071 | 623-859 | STKc_SIK |
| cd07830 | 622-817 | STKc_MAK_like |
| cd14137 | 621-818 | STKc_GSK3 |
| cd13997 | 627-875 | PKc_Wee1_like |
| cd08220 | 624-874 | STKc_Nek8 |
| cd09549 | 908-976 | SAM_EPH-A10 |
| cd09550 | 915-976 | SAM_EPH-A8 |
| cd07833 | 626-822 | STKc_CDKL |
| cd09552 | 908-978 | SAM_EPH-B2 |
| cd14162 | 625-865 | STKc_TSSK4-like |
| cd09553 | 908-976 | SAM_EPH-B3 |
| cd14079 | 622-844 | STKc_AMPK_alpha |
| cd14072 | 622-849 | STKc_MARK |
| cd14057 | 650-881 | PK_ILK |
| cd07843 | 630-819 | STKc_CDC2L1 |
| cd14042 | 650-881 | PK_GC-A_B |
| cd08218 | 625-877 | STKc_Nek1 |
| cd14075 | 622-876 | STKc_NIM1 |
| cd14201 | 626-871 | STKc_ULK2 |
| cd06659 | 593-846 | STKc_PAK6 |
| cd14056 | 625-861 | STKc_TGFbR_I |
| cd06642 | 622-848 | STKc_STK25 |
| cd07866 | 622-824 | STKc_BUR1 |
| cd14103 | 627-833 | STKc_MLCK |
| cd14055 | 625-861 | STKc_TGFbR2_like |
| cd13996 | 622-816 | STKc_EIF2AK |
| cd07841 | 622-818 | STKc_CDK7 |
| cd13998 | 626-819 | STKc_TGFbR-like |
| cd14073 | 623-846 | STKc_NUAK |
| cd14120 | 627-872 | STKc_ULK1_2-like |
| cd14167 | 625-837 | STKc_CaMKI_alpha |
| cd14190 | 621-825 | STKc_MLCK2 |
| pfam07647 | 908-973 | SAM_2 |
| cd07859 | 622-819 | STKc_TDY_MAPK |
| cd05077 | 645-875 | PTK_Jak1_rpt1 |
| cd08224 | 622-874 | STKc_Nek6_7 |
| cd13994 | 627-832 | STKc_HAL4_like |
| cd14045 | 650-881 | PK_GC_unk |
| cd05581 | 622-848 | STKc_PDK1 |
| cd14097 | 627-840 | STKc_STK33 |
| cd09547 | 913-973 | SAM_EPH-A6 |
| cd14164 | 622-874 | STKc_TSSK6-like |
| cd05123 | 627-848 | STKc_AGC |
| cd08217 | 625-877 | STKc_Nek2 |
| cd06619 | 621-869 | PKc_MKK5 |
| cd14156 | 627-881 | PKc_LIMK_like_unk |
| cd06630 | 670-870 | STKc_MEKK1 |
| cd06624 | 611-830 | STKc_ASK |
| cd07855 | 622-824 | STKc_ERK5 |
| cd14208 | 646-879 | PTK_Jak3_rpt1 |
| cd05578 | 622-857 | STKc_Yank1 |
| cd09546 | 915-976 | SAM_EPH-A5 |
| cd06621 | 624-870 | PKc_Pek1_like |
| cd07849 | 622-819 | STKc_ERK1_2_like |
| cd06613 | 627-845 | STKc_MAP4K3_like |
| cd13986 | 622-882 | STKc_16 |
| cd07858 | 615-818 | STKc_TEY_MAPK |
| cd06626 | 625-831 | STKc_MEKK4 |
| cd06608 | 626-828 | STKc_myosinIII_N_like |
| cd06917 | 625-837 | STKc_NAK1_like |
| cd13989 | 627-825 | STKc_IKK |
| cd06644 | 627-875 | STKc_STK10 |
| cd14001 | 651-880 | PKc_TOPK |
| cd08223 | 625-875 | STKc_Nek4 |
| cd06617 | 647-877 | PKc_MKK3_6 |
| cd14161 | 625-859 | STKc_NUAK2 |
| cd13990 | 627-834 | STKc_TLK |
| cd06658 | 604-845 | STKc_PAK5 |
| cd14165 | 622-830 | STKc_TSSK1_2-like |
| cd08219 | 623-869 | STKc_Nek3 |
| cd14044 | 645-881 | PK_GC-C |
| cd14152 | 621-881 | STKc_KSR1 |
| cd06625 | 625-869 | STKc_MEKK3_like |
| cd07832 | 678-818 | STKc_CCRK |
| cd14095 | 620-846 | STKc_DCKL |
| cd14159 | 627-881 | STKc_IRAK1 |
| cd07856 | 627-818 | STKc_Sty1_Hog1 |
| cd13983 | 657-842 | STKc_WNK |
| cd14006 | 627-848 | STKc_MLCK-like |
| cd06643 | 627-850 | STKc_SLK |
| cd07851 | 623-816 | STKc_p38 |
| cd14116 | 622-837 | STKc_Aurora-A |
| cd14039 | 627-825 | STKc_IKK_alpha |
| pfam00536 | 915-973 | SAM_1 |
| cd14083 | 622-841 | STKc_CaMKI |
| cd07845 | 624-818 | STKc_CDK10 |
| cd09555 | 908-976 | SAM_EPH-B6 |
| cd14067 | 636-875 | STKc_LRRK1 |
| cd14082 | 624-833 | STKc_PKD |
| cd14106 | 624-832 | STKc_DRAK |
| cd06607 | 627-869 | STKc_TAO |
| cd05612 | 622-848 | STKc_PRKX_like |
| cd14166 | 625-841 | STKc_CaMKI_gamma |
| cd14038 | 627-872 | STKc_IKK_beta |
| cd14175 | 623-825 | STKc_RSK1_C |
| cd07852 | 622-816 | STKc_MAPK15-like |
| cd14184 | 622-846 | STKc_DCKL2 |
| cd14188 | 663-875 | STKc_PLK2 |
| cd14010 | 627-825 | STKc_ULK4 |
| cd14098 | 623-852 | STKc_Rad53_Cds1 |
| cd14076 | 623-827 | STKc_Kin4 |
| cd14050 | 620-859 | PKc_Myt1 |
| cd14143 | 626-861 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd14105 | 627-837 | STKc_DAPK |
| cd06657 | 627-847 | STKc_PAK4 |
| cd08221 | 660-877 | STKc_Nek9 |
| cd14193 | 621-825 | STKc_MLCK4 |
| cd07864 | 626-831 | STKc_CDK12 |
| cd14189 | 663-875 | STKc_PLK3 |
| cd14160 | 627-881 | PK_IRAK3 |
| cd14194 | 627-837 | STKc_DAPK1 |
| cd06622 | 627-876 | PKc_PBS2_like |
| cd06631 | 626-876 | STKc_YSK4 |
| cd13985 | 621-880 | STKc_GAK_like |
| cd14068 | 626-879 | STKc_LRRK2 |
| cd14186 | 622-876 | STKc_PLK4 |
| cd14192 | 625-825 | STKc_MLCK3 |
| cd14041 | 626-874 | STKc_TLK2 |
| cd08229 | 599-881 | STKc_Nek7 |
| cd14040 | 626-876 | STKc_TLK1 |
| cd14142 | 692-881 | STKc_ACVR1_ALK1 |
| cd06615 | 664-824 | PKc_MEK |
| cd14191 | 623-832 | STKc_MLCK1 |
| cd05582 | 625-825 | STKc_RSK_N |
| cd14087 | 623-827 | STKc_PSKH1 |
| cd14665 | 625-827 | STKc_SnRK2-3 |
| cd14177 | 627-830 | STKc_RSK4_C |
| cd07857 | 622-824 | STKc_MPK1 |
| cd14077 | 625-840 | STKc_Kin1_2 |
| cd08228 | 622-874 | STKc_Nek6 |
| cd05572 | 627-825 | STKc_cGK |
| cd14176 | 622-825 | STKc_RSK2_C |
| cd14153 | 621-881 | PK_KSR2 |
| cd14004 | 623-876 | STKc_PASK |
| cd06647 | 604-837 | STKc_PAK_I |
| cd07865 | 612-816 | STKc_CDK9 |
| cd06618 | 615-874 | PKc_MKK7 |
| cd14144 | 625-861 | STKc_BMPR1 |
| cd06636 | 618-846 | STKc_MAP4K4_6_N |
| cd14172 | 624-843 | STKc_MAPKAPK3 |
| cd06633 | 627-875 | STKc_TAO3 |
| cd14178 | 622-825 | STKc_RSK3_C |
| cd14089 | 625-847 | STKc_MAPKAPK |
| cd14196 | 623-837 | STKc_DAPK2 |
| cd14047 | 627-878 | STKc_EIF2AK2_PKR |
| cd14183 | 622-815 | STKc_DCKL1 |
| cd14091 | 623-841 | STKc_RSK_C |
| cd07853 | 627-819 | STKc_NLK |
| cd06635 | 627-927 | STKc_TAO1 |
| cd14109 | 665-840 | PK_Unc-89_rpt1 |
| cd07860 | 622-819 | STKc_CDK2_3 |
| pfam00041 | 447-525 | fn3 |
| cd05620 | 625-825 | STKc_nPKC_delta |
| cd14209 | 625-844 | STKc_PKA |
| cd14179 | 624-840 | STKc_MSK1_C |
| cd07838 | 627-816 | STKc_CDK4_6_like |
| cd06634 | 627-927 | STKc_TAO2 |
| cd07836 | 622-819 | STKc_Pho85 |
| cd05604 | 625-826 | STKc_SGK3 |
| cd14180 | 679-840 | STKc_MSK2_C |
| cd06616 | 627-877 | PKc_MKK4 |
| cd09543 | 915-976 | SAM_EPH-A2 |
| cd14168 | 622-837 | STKc_CaMKI_delta |
| cd05615 | 626-839 | STKc_cPKC_alpha |
| cd14093 | 664-846 | STKc_PhKG |
| cd05579 | 627-896 | STKc_MAST_like |
| cd06637 | 618-886 | STKc_TNIK |
| cd14198 | 626-832 | STKc_DRAK2 |
| cd07863 | 627-851 | STKc_CDK4 |
| cd08528 | 627-877 | STKc_Nek10 |
| cd14220 | 625-881 | STKc_BMPR1a |
| cd14662 | 625-827 | STKc_SnRK2 |
| cd14117 | 623-847 | STKc_Aurora-B_like |
| cd05602 | 625-868 | STKc_SGK1 |
| cd14070 | 623-825 | STKc_HUNK |
| cd13982 | 721-869 | STKc_IRE1 |
| cd14096 | 623-841 | STKc_RCK1-like |
| cd14119 | 650-874 | STKc_LKB1 |
| cd14187 | 663-876 | STKc_PLK1 |
| cd14185 | 622-848 | STKc_DCKL3 |
| cd06638 | 622-867 | STKc_myosinIIIA_N |
| cd06650 | 664-824 | PKc_MEK1 |
| cd14074 | 623-876 | STKc_SNRK |
| cd07877 | 627-846 | STKc_p38alpha |
| cd07831 | 622-846 | STKc_MOK |
| cd07846 | 626-822 | STKc_CDKL2_3 |
| cd06652 | 622-826 | STKc_MEKK2 |
| cd14048 | 625-818 | STKc_EIF2AK3_PERK |
| cd07878 | 627-818 | STKc_p38beta |
| cd05619 | 623-847 | STKc_nPKC_theta |
| cd07880 | 625-819 | STKc_p38gamma |
| cd05616 | 625-839 | STKc_cPKC_beta |
| cd05574 | 625-825 | STKc_phototropin_like |
| cd07871 | 621-824 | STKc_PCTAIRE3 |
| cd07854 | 627-819 | STKc_MAPK4_6 |
| cd14195 | 627-837 | STKc_DAPK3 |
| cd07879 | 600-819 | STKc_p38delta |
| cd13988 | 627-825 | STKc_TBK1 |
| cd07847 | 622-826 | STKc_CDKL1_4 |
| cd07872 | 621-819 | STKc_PCTAIRE2 |
| cd09542 | 915-971 | SAM_EPH-A1 |
| cd07848 | 626-817 | STKc_CDKL5 |
| cd05593 | 625-837 | STKc_PKB_gamma |
| cd06653 | 622-826 | STKc_MEKK3_like_u1 |
| cd07850 | 625-816 | STKc_JNK |
| cd14078 | 623-845 | STKc_MELK |
| cd14169 | 619-837 | STKc_CaMKI_beta |
| cd05601 | 623-825 | STKc_CRIK |
| cd05592 | 625-825 | STKc_nPKC_theta_like |
| cd05603 | 625-833 | STKc_SGK2 |
| cd14046 | 625-876 | STKc_EIF2AK4_GCN2_rpt2 |
| smart00060 | 441-522 | FN3 |
| cd05570 | 625-839 | STKc_PKC |
| cd14114 | 623-825 | STKc_Twitchin_like |
| cd06655 | 627-837 | STKc_PAK2 |
| cd14088 | 625-832 | STKc_CaMK_like |
| cd05630 | 625-841 | STKc_GRK6 |
| cd07839 | 622-824 | STKc_CDK5 |
| cd07862 | 627-850 | STKc_CDK6 |
| cd06651 | 625-826 | STKc_MEKK3 |
| cd05611 | 625-840 | STKc_Rim15_like |
| cd07869 | 622-818 | STKc_PFTAIRE1 |
| cd14086 | 622-846 | STKc_CaMKII |
| cd06656 | 622-837 | STKc_PAK3 |
| cd06654 | 622-837 | STKc_PAK1 |
| cd06639 | 623-846 | STKc_myosinIIIB_N |
| cd05599 | 625-825 | STKc_NDR_like |
| cd05595 | 625-844 | STKc_PKB_beta |
| cd14170 | 693-884 | STKc_MAPKAPK2 |
| cd05573 | 625-845 | STKc_ROCK_NDR_like |
| cd07873 | 621-824 | STKc_PCTAIRE1 |
| cd14197 | 678-825 | STKc_DRAK1 |
| cd05631 | 625-839 | STKc_GRK4 |
| cd07861 | 621-824 | STKc_CDK1_euk |
| cd14133 | 622-846 | PKc_DYRK_like |
| cd14104 | 623-839 | STKc_Titin |
| cd09490 | 911-971 | SAM_Arap1,2,3 |
| cd05624 | 596-844 | STKc_MRCK_beta |
| cd05613 | 625-825 | STKc_MSK1_N |
| cd14012 | 676-869 | PK_eIF2AK_GCN2_rpt1 |
| cd07874 | 625-897 | STKc_JNK3 |
| cd06649 | 664-824 | PKc_MEK2 |
| cd06645 | 627-885 | STKc_MAP4K3 |
| cd14049 | 627-874 | STKc_EIF2AK1_HRI |
| cd05584 | 625-846 | STKc_p70S6K |
| cd14113 | 631-829 | STKc_Trio_C |
| cd05585 | 626-848 | STKc_YPK1_like |
| cd05632 | 625-825 | STKc_GRK5 |
| cd07842 | 622-820 | STKc_CDK8_like |
| cd07876 | 625-818 | STKc_JNK2 |
| cd14031 | 660-876 | STKc_WNK3 |
| pfam00041 | 330-419 | fn3 |
| cd05590 | 625-837 | STKc_nPKC_eta |
| cd05607 | 625-827 | STKc_GRK7 |
| cd05571 | 625-832 | STKc_PKB |
| cd13975 | 732-884 | PKc_Dusty |
| cd14051 | 626-869 | PTKc_Wee1 |
| smart00060 | 329-419 | FN3 |
| cd14181 | 664-846 | STKc_PhKG2 |
| cd07875 | 625-821 | STKc_JNK1 |
| cd13993 | 621-814 | STKc_Pat1_like |
| cd14138 | 622-755 | PTKc_Wee1a |
| cd14033 | 621-830 | STKc_WNK4 |
| cd14101 | 743-875 | STKc_PIM2 |
| cd05623 | 586-829 | STKc_MRCK_alpha |
| cd05622 | 602-826 | STKc_ROCK1 |
| cd05594 | 625-844 | STKc_PKB_alpha |
| cd08226 | 677-828 | PK_STRAD_beta |
| cd05591 | 625-837 | STKc_nPKC_epsilon |
| cd13987 | 627-826 | STKc_SBK1 |
| cd13991 | 627-825 | STKc_NIK |
| cd14085 | 623-827 | STKc_CaMKIV |
| cd05587 | 625-825 | STKc_cPKC |
| cd14200 | 670-827 | STKc_CaMKK1 |
| cd09487 | 915-970 | SAM_superfamily |
| cd13995 | 630-876 | STKc_MAP3K8 |
| cd05586 | 627-844 | STKc_Sck1_like |
| cd14141 | 679-863 | STKc_ACVR2a |
| cd14030 | 617-830 | STKc_WNK1 |
| cd14199 | 670-827 | STKc_CaMKK2 |
| cd06646 | 627-847 | STKc_MAP4K5 |
| cd14036 | 621-881 | STKc_GAK |
| cd14219 | 618-868 | STKc_BMPR1b |
| cd14094 | 620-847 | STKc_CASK |
| cd05589 | 626-825 | STKc_PKN |
| cd07835 | 622-816 | STKc_CDK1_CdkB_like |
| cd05621 | 602-860 | STKc_ROCK2 |
| cd14005 | 622-876 | STKc_PIM |
| cd05596 | 612-829 | STKc_ROCK |
| cd14032 | 660-830 | STKc_WNK2_like |
| cd00185 | 273-327 | TNFRSF |
| cl22855 | 273-327 | TNFRSF superfamily |
| pfam07714 | 621-878 | Pkinase_Tyr |
| smart00219 | 621-878 | TyrKc |
| smart00221 | 621-878 | STYKc |
| smart00220 | 622-877 | S_TKc |
| pfam00069 | 621-876 | Pkinase |
| COG0515 | 622-915 | SPS1 |
| PLN00034 | 627-905 | PLN00034 |
| PHA03209 | 610-820 | PHA03209 |
| PTZ00024 | 615-819 | PTZ00024 |
| smart00454 | 915-975 | SAM |
| PTZ00263 | 621-840 | PTZ00263 |
| PHA03212 | 588-817 | PHA03212 |
| PTZ00426 | 625-885 | PTZ00426 |
| TIGR03903 | 650-834 | TOMM_kin_cyc |
| PTZ00267 | 661-915 | PTZ00267 |
| PLN00009 | 622-824 | PLN00009 |
| PTZ00266 | 599-844 | PTZ00266 |
| PHA02988 | 650-881 | PHA02988 |
Ontology Information
| HPRD ID | 3952 |
|---|---|
| Molecular Class | Receptor tyrosine kinase |
| Molecular Function | Protein serine/threonine kinase activity (GO:0004674) |
| Biological Process | Regulation of cell proliferation (GO:0042127); Apoptosis (GO:0006915); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.