Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24151532 | 2013 | Cell line : - Source : Capital Health district of Nova Scotia. Sample Type : CRC tumor and normal tissue No. of Sample : 159 Stage : TNM Stage I-IV. | Tissue microarrays, immunohistochemistry,Univariate and Multivariate Analyses | Down-regulation | - | Decreased EphB2 expression was an independent prognostic factor for recurrence and death and may have prognostic relevance in tumors with MSI-H. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | EPH receptors, "Sterile alpha motif (SAM) domain containing", "Fibronectin type III domain containing" |
| Description | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] | Chromosome | 1 |
| Location | 1p36.1-p35 |
| Start | 23037263 |
| End | 23241823 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 204561 |
| OMIM ID | 600997 |
| HGNC ID | HGNC:3393 |
| Unigene ID | Hs.380705 |
| Ensembl ID | ENSG00000133216 |
| PharmGKB ID | PA27825 |
mRNA Information
| mRNA ID | XM_006710442.2 |
|---|---|
| Exon | join(1..274,70652..70716,73623..74307,152268..152423, 154108..154443,171590..171714,182208..182277, 184703..184811,185642..185709,195218..195340, 195941..196188,197184..197399,198253..198402, 199613..199806,201675..201830,202693..204558) | mRNA Sequence | Download Select all |
| Length | 4841 |
Protein Information
| Protein ID | XP_006710505.1 |
|---|---|
| Protein Name | EPH receptor B2 |
| Molecular Wt. (Da) | 106603 |
| Protein Sequence | Download Select all |
| Length | 956 |
| Uniprot ID | P45983 |
| Ensembl Protein ID | ENSP00000353483 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 577 |
| Y | Phosphorylation | 584 |
| Y | Phosphorylation | 596 |
| Y | Phosphorylation | 659 |
| Y | Phosphorylation | 736 |
| Y | Phosphorylation | 742 |
| Y | Phosphorylation | 780 |
| Y | Phosphorylation | 800 |
| Y | Phosphorylation | 930 |
| Y | Phosphorylation | 578 |
| Y | Phosphorylation | 585 |
| Y | Phosphorylation | 597 |
| Y | Phosphorylation | 660 |
| Y | Phosphorylation | 737 |
| Y | Phosphorylation | 743 |
| Y | Phosphorylation | 781 |
| Y | Phosphorylation | 801 |
| Y | Phosphorylation | 931 |
| Y | Phosphorylation | 602 |
| Y | Phosphorylation | 603 |
| S | Phosphorylation | 776;- |
| S | Phosphorylation | 777;- |
| T | Phosphorylation | 775;- |
| T | Phosphorylation | 776;- |
| N | Glycosylation | 481 |
| N | Glycosylation | 481 |
| Y | Phosphorylation | 595 |
| Y | Phosphorylation | 596 |
| Y | Phosphorylation | 601 |
| Y | Phosphorylation | 602 |
| Y | Phosphorylation | 779 |
| Y | Phosphorylation | 780 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 25 | ABL1 | 1809 | NP_009297.2 | in vivo;yeast 2-hybrid | 11494128 |
| 27 | ABL2 | 1259 | NP_009298.1 | in vitro;in vivo;yeast 2-hybrid | 11494128 |
| 358 | AQP1 | 140 | NP_000376.1 | in vivo;yeast 2-hybrid | 10839360 |
| 1947 | EFNB1 | 2072 | NP_004420.1 | in vitro;in vivo | 8878483 |
| 1948 | EFNB2 | 2754 | NP_004084.1 | in vitro;in vivo | 11780069 |
| 2077 | ERF | 9942 | NP_006485.2 | in vitro;in vivo | 10330152 |
| 2353 | FOS | 1275 | NP_005243.1 | in vitro;in vivo | 781 660 212 972 619 |
| 2885 | GRB2 | 150 | NP_002077.1 | in vivo | 16298995 |
| 4301 | MLLT4 | 1164 | NP_001035090.1 | in vitro;in vivo;yeast 2-hybrid | 9707552 |
| 4690 | NCK1 | 2740 | NP_006144.1 | in vitro;in vivo | 9233798 |
| 5747 | PTK2 | 2859 | NP_005598.3 | in vivo | 1 629 899 518 713 740 |
| 5921 | RASA1 | 745 | NP_002881.1 | in vitro | 923 379 810 644 995 |
| 6237 | RRAS | 1299 | NP_006261.1 | in vitro | 10570155 |
| 6259 | RYK | 2751 | NP_001005861.1 | in vivo | 11956217 |
| 6383 | SDC2 | 803 | NP_002989.2 | in vivo | 11580899 |
| 6386 | SDCBP | 3741 | NP_005616.2 | in vitro;yeast 2-hybrid | 9883737 |
| 6714 | SRC | 1819 | NP_005408.1 | in vivo;yeast 2-hybrid | 963 214 218 713 744 |
| 7410 | VAV2 | 2694 | NP_001127870.1 | in vitro | 15848800 |
| 8997 | KALRN | 6859 | NP_001019831.2 | in vitro | 12546821 |
| 9459 | ARHGEF6 | 2226 | NP_004831.1 | in vitro | 10523848 |
| 9463 | PICK1 | 16176 | NP_036539.1 | in vitro;yeast 2-hybrid | 988 373 710 839 360 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Axon guidance | hsa04360 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05065 | 616-884 | PTKc_EphR_B |
| cl21453 | 616-884 | PKc_like superfamily |
| cd10477 | 19-196 | EphR_LBD_B2 |
| cl02704 | 19-196 | EphR_LBD superfamily |
| cd09552 | 910-980 | SAM_EPH-B2 |
| cl15755 | 910-980 | SAM_superfamily superfamily |
| cd00063 | 436-527 | FN3 |
| cl21522 | 436-527 | FN3 superfamily |
| cd00063 | 325-431 | FN3 |
| cl21522 | 325-431 | FN3 superfamily |
| cd05033 | 616-884 | PTKc_EphR |
| cd05066 | 616-884 | PTKc_EphR_A |
| cd05063 | 615-884 | PTKc_EphR_A2 |
| cd05064 | 615-884 | PTKc_EphR_A10 |
| cd10472 | 21-196 | EphR_LBD_B |
| cd00192 | 626-881 | PTKc |
| pfam01404 | 20-197 | Ephrin_lbd |
| smart00615 | 20-196 | EPH_lbd |
| cd10476 | 21-196 | EphR_LBD_B1 |
| cd10478 | 20-196 | EphR_LBD_B3 |
| cd05034 | 627-881 | PTKc_Src_like |
| cd10319 | 21-196 | EphR_LBD |
| cd05068 | 615-873 | PTKc_Frk_like |
| cd05041 | 625-881 | PTKc_Fes_like |
| cd05060 | 627-880 | PTKc_Syk_like |
| cd10473 | 20-196 | EphR_LBD_A |
| cd05039 | 615-880 | PTKc_Csk_like |
| cd05056 | 615-880 | PTKc_FAK |
| cd05059 | 616-880 | PTKc_Tec_like |
| cd05148 | 623-881 | PTKc_Srm_Brk |
| cd05067 | 615-881 | PTKc_Lck_Blk |
| cd05048 | 615-880 | PTKc_Ror |
| cd05052 | 615-884 | PTKc_Abl |
| cd13999 | 627-880 | STKc_MAP3K-like |
| cd05032 | 615-881 | PTKc_InsR_like |
| cd05040 | 627-880 | PTKc_Ack_like |
| cd14203 | 627-873 | PTKc_Src_Fyn_like |
| cd05057 | 625-887 | PTKc_EGFR_like |
| cd05072 | 613-881 | PTKc_Lyn |
| cd10485 | 19-197 | EphR_LBD_A7 |
| cd05049 | 615-882 | PTKc_Trk |
| cd10487 | 23-196 | EphR_LBD_A10 |
| cd05044 | 627-880 | PTKc_c-ros |
| cd10475 | 20-196 | EphR_LBD_B6 |
| cd05112 | 616-880 | PTKc_Itk |
| cd10481 | 20-196 | EphR_LBD_A3 |
| cd05084 | 625-880 | PTKc_Fes |
| cd05051 | 622-876 | PTKc_DDR |
| cd10486 | 20-196 | EphR_LBD_A8 |
| cd10484 | 23-196 | EphR_LBD_A6 |
| cd05085 | 625-880 | PTKc_Fer |
| cd10482 | 20-196 | EphR_LBD_A4 |
| cd05115 | 623-880 | PTKc_Zap-70 |
| cd05069 | 613-881 | PTKc_Yes |
| cd05073 | 613-881 | PTKc_Hck |
| cd05113 | 627-880 | PTKc_Btk_Bmx |
| cd10483 | 20-196 | EphR_LBD_A5 |
| cd05036 | 614-882 | PTKc_ALK_LTK |
| cd05070 | 615-873 | PTKc_Fyn |
| cd05050 | 622-876 | PTKc_Musk |
| cd05071 | 613-873 | PTKc_Src |
| cd10474 | 20-196 | EphR_LBD_B4 |
| cd05114 | 627-884 | PTKc_Tec_Rlk |
| cd05038 | 627-881 | PTKc_Jak_rpt2 |
| cd05083 | 616-883 | PTKc_Chk |
| cd05090 | 615-876 | PTKc_Ror1 |
| cd05091 | 614-880 | PTKc_Ror2 |
| cd05058 | 625-877 | PTKc_Met_Ron |
| cd05053 | 611-884 | PTKc_FGFR |
| cd05092 | 627-880 | PTKc_TrkA |
| cd05109 | 614-888 | PTKc_HER2 |
| cd05045 | 623-886 | PTKc_RET |
| cd05095 | 627-880 | PTKc_DDR2 |
| cd05116 | 627-873 | PTKc_Syk |
| cd05046 | 626-882 | PTK_CCK4 |
| cd05097 | 621-876 | PTKc_DDR_like |
| cd05108 | 622-888 | PTKc_EGFR |
| cd05082 | 621-881 | PTKc_Csk |
| cd05035 | 621-884 | PTKc_TAM |
| cd05096 | 619-876 | PTKc_DDR1 |
| cd05075 | 621-886 | PTKc_Axl |
| cd05093 | 621-885 | PTKc_TrkB |
| cd05061 | 627-880 | PTKc_InsR |
| cd05110 | 614-887 | PTKc_HER4 |
| cd14204 | 616-884 | PTKc_Mer |
| cd05055 | 595-884 | PTKc_PDGFR |
| cd10480 | 20-197 | EphR_LBD_A2 |
| cd05047 | 626-883 | PTKc_Tie |
| cd05074 | 625-881 | PTKc_Tyro3 |
| cd05101 | 602-884 | PTKc_FGFR2 |
| cd05089 | 621-894 | PTKc_Tie1 |
| cd05094 | 623-883 | PTKc_TrkC |
| cd05099 | 627-884 | PTKc_FGFR4 |
| cd05111 | 625-887 | PTK_HER3 |
| cd05088 | 616-884 | PTKc_Tie2 |
| cd00180 | 627-880 | PKc |
| cd05098 | 627-884 | PTKc_FGFR1 |
| cd05062 | 627-880 | PTKc_IGF-1R |
| cd05054 | 611-880 | PTKc_VEGFR |
| cd05043 | 621-880 | PTK_Ryk |
| cd14205 | 621-883 | PTKc_Jak2_rpt2 |
| cd05100 | 627-884 | PTKc_FGFR3 |
| cd10479 | 20-196 | EphR_LBD_A1 |
| cd14207 | 611-880 | PTKc_VEGFR1 |
| cd05079 | 627-884 | PTKc_Jak1_rpt2 |
| cd05103 | 621-885 | PTKc_VEGFR2 |
| cd14014 | 622-872 | STKc_PknB_like |
| cd05102 | 621-885 | PTKc_VEGFR3 |
| cd14058 | 627-880 | STKc_TAK1 |
| cd05107 | 600-884 | PTKc_PDGFR_beta |
| cd05106 | 621-885 | PTKc_CSF-1R |
| cd05080 | 621-883 | PTKc_Tyk2_rpt2 |
| cd13978 | 627-880 | STKc_RIP |
| cd14062 | 627-881 | STKc_Raf |
| cd05105 | 595-884 | PTKc_PDGFR_alpha |
| cd14059 | 627-881 | STKc_MAP3K12_13 |
| cd14061 | 626-883 | STKc_MLK |
| cd05081 | 621-883 | PTKc_Jak3_rpt2 |
| cd05122 | 620-871 | PKc_STE |
| cd06606 | 625-871 | STKc_MAPKKK |
| cd05104 | 595-884 | PTKc_Kit |
| cd06627 | 627-871 | STKc_Cdc7_like |
| cd14066 | 627-883 | STKc_IRAK |
| cd14060 | 628-883 | STKc_MLTK |
| cd14145 | 615-880 | STKc_MLK1 |
| cd14150 | 621-885 | STKc_A-Raf |
| cd14154 | 627-883 | STKc_LIMK |
| cd05042 | 625-863 | PTKc_Aatyk |
| cd14149 | 615-881 | STKc_C-Raf |
| cd14146 | 626-880 | STKc_MLK4 |
| cd14151 | 615-886 | STKc_B-Raf |
| cd14221 | 627-886 | STKc_LIMK1 |
| cd05086 | 625-863 | PTKc_Aatyk2 |
| cd14148 | 626-881 | STKc_MLK2 |
| cd14003 | 622-878 | STKc_AMPK-like |
| cd14206 | 625-876 | PTKc_Aatyk3 |
| cd14147 | 621-883 | STKc_MLK3 |
| cd13992 | 641-883 | PK_GC |
| cd08215 | 622-879 | STKc_Nek |
| cd09553 | 910-978 | SAM_EPH-B3 |
| cd09488 | 914-974 | SAM_EPH-R |
| cd05117 | 622-848 | STKc_CAMK |
| pfam14575 | 543-617 | EphA2_TM |
| cl22928 | 543-617 | EphA2_TM superfamily |
| cd14222 | 627-883 | STKc_LIMK2 |
| cd09551 | 910-977 | SAM_EPH-B1 |
| cd05087 | 627-871 | PTKc_Aatyk1 |
| cd14064 | 627-881 | PKc_TNNI3K |
| cd05037 | 623-880 | PTK_Jak_rpt1 |
| cd06623 | 617-886 | PKc_MAPKK_plant_like |
| cd14065 | 627-880 | PKc_LIMK_like |
| cd14009 | 627-859 | STKc_ATG1_ULK_like |
| cd06614 | 625-871 | STKc_PAK |
| cd14008 | 627-876 | STKc_LKB1_CaMKK |
| cd14080 | 623-878 | STKc_TSSK-like |
| cd06612 | 623-871 | STKc_MST1_2 |
| cd09554 | 913-977 | SAM_EPH-B4 |
| cd06628 | 626-871 | STKc_Byr2_like |
| cd06632 | 625-878 | STKc_MEKK1_plant |
| cd06640 | 627-871 | STKc_MST4 |
| cd14026 | 650-885 | STKc_RIP2 |
| cd07840 | 622-818 | STKc_CDK9_like |
| cd14025 | 627-876 | STKc_RIP4_like |
| cd06609 | 622-871 | STKc_MST3_like |
| cd06629 | 625-871 | STKc_Bck1_like |
| cd14027 | 629-878 | STKc_RIP1 |
| cd14063 | 621-885 | PK_KSR |
| cd14002 | 625-870 | STKc_STK36 |
| cd07834 | 622-820 | STKc_MAPK |
| cd06610 | 622-887 | STKc_OSR1_SPAK |
| cd14054 | 625-870 | STKc_BMPR2_AMHR2 |
| cd09548 | 910-978 | SAM_EPH-A7 |
| cd09546 | 914-978 | SAM_EPH-A5 |
| cd14155 | 627-885 | PKc_TESK |
| cd14664 | 627-826 | STK_BAK1_like |
| cd13979 | 621-871 | STKc_Mos |
| cd14007 | 622-878 | STKc_Aurora |
| cd06620 | 627-871 | PKc_Byr1_like |
| cd06641 | 604-877 | STKc_MST3 |
| cd09555 | 910-978 | SAM_EPH-B6 |
| cd06611 | 627-885 | STKc_SLK_like |
| cd06605 | 626-878 | PKc_MAPKK |
| pfam00536 | 911-975 | SAM_1 |
| cd14158 | 627-821 | STKc_IRAK4 |
| cd08222 | 623-879 | STKc_Nek11 |
| cd14053 | 625-821 | STKc_ACVR2 |
| cd05078 | 624-881 | PTK_Jak2_rpt1 |
| cd05118 | 626-859 | STKc_CMGC |
| cd06648 | 627-848 | STKc_PAK_II |
| cd14202 | 624-873 | STKc_ULK1 |
| cd07830 | 622-871 | STKc_MAK_like |
| cd08529 | 627-887 | STKc_FA2-like |
| cd14056 | 626-863 | STKc_TGFbR_I |
| cd07829 | 622-888 | STKc_CDK_like |
| cd13997 | 624-877 | PKc_Wee1_like |
| cd14099 | 627-878 | STKc_PLK |
| cd14043 | 650-876 | PK_GC-2D |
| cd14000 | 626-880 | STKc_LRRK |
| cd06642 | 627-871 | STKc_STK25 |
| cd13998 | 625-866 | STKc_TGFbR-like |
| cd13996 | 622-880 | STKc_EIF2AK |
| cd14055 | 625-870 | STKc_TGFbR2_like |
| cd09547 | 915-975 | SAM_EPH-A6 |
| cd14042 | 649-883 | PK_GC-A_B |
| cd14069 | 621-829 | STKc_Chk1 |
| cd09550 | 917-978 | SAM_EPH-A8 |
| cd14071 | 623-861 | STKc_SIK |
| cd14120 | 627-874 | STKc_ULK1_2-like |
| cd05077 | 645-877 | PTK_Jak1_rpt1 |
| cd14121 | 627-873 | STKc_ULK3 |
| cd14084 | 610-816 | STKc_Chk2 |
| cd07851 | 623-818 | STKc_p38 |
| cd05076 | 667-880 | PTK_Tyk2_rpt1 |
| cd14201 | 626-873 | STKc_ULK2 |
| cd05123 | 627-874 | STKc_AGC |
| cd07849 | 622-821 | STKc_ERK1_2_like |
| cd14073 | 623-878 | STKc_NUAK |
| cd14045 | 650-883 | PK_GC_unk |
| cd08224 | 622-876 | STKc_Nek6_7 |
| cd14162 | 626-846 | STKc_TSSK4-like |
| cd14103 | 627-827 | STKc_MLCK |
| cd09545 | 913-982 | SAM_EPH-A4 |
| cd08225 | 625-877 | STKc_Nek5 |
| cd14052 | 627-879 | PTKc_Wee1_fungi |
| cd07866 | 622-826 | STKc_BUR1 |
| cd14167 | 625-887 | STKc_CaMKI_alpha |
| cd07859 | 622-821 | STKc_TDY_MAPK |
| cd14137 | 622-820 | STKc_GSK3 |
| cd14190 | 624-839 | STKc_MLCK2 |
| cd14057 | 650-883 | PK_ILK |
| cd14044 | 645-883 | PK_GC-C |
| cd14663 | 622-847 | STKc_SnRK3 |
| cd05580 | 621-850 | STKc_PKA_like |
| cd06631 | 625-878 | STKc_YSK4 |
| cd13994 | 627-816 | STKc_HAL4_like |
| cd06644 | 604-896 | STKc_STK10 |
| cd14165 | 627-870 | STKc_TSSK1_2-like |
| cd14159 | 627-826 | STKc_IRAK1 |
| cd09543 | 915-979 | SAM_EPH-A2 |
| cd06659 | 627-848 | STKc_PAK6 |
| pfam07647 | 910-975 | SAM_2 |
| cd14081 | 622-861 | STKc_BRSK1_2 |
| cd08220 | 624-876 | STKc_Nek8 |
| cd14156 | 664-883 | PKc_LIMK_like_unk |
| cd07843 | 627-821 | STKc_CDC2L1 |
| cd05578 | 622-859 | STKc_Yank1 |
| cd08217 | 625-871 | STKc_Nek2 |
| cd06643 | 627-853 | STKc_SLK |
| cd14038 | 627-874 | STKc_IKK_beta |
| cd08530 | 622-879 | STKc_CNK2-like |
| cd06630 | 670-872 | STKc_MEKK1 |
| cd06658 | 604-847 | STKc_PAK5 |
| cd14097 | 627-827 | STKc_STK33 |
| cd14072 | 622-860 | STKc_MARK |
| cd14075 | 618-847 | STKc_NIM1 |
| cd14010 | 649-878 | STKc_ULK4 |
| cd14079 | 622-829 | STKc_AMPK_alpha |
| cd07855 | 622-826 | STKc_ERK5 |
| cd08228 | 622-883 | STKc_Nek6 |
| cd07841 | 627-820 | STKc_CDK7 |
| cd06917 | 625-829 | STKc_NAK1_like |
| cd13989 | 627-827 | STKc_IKK |
| cd06621 | 630-872 | PKc_Pek1_like |
| cd14152 | 621-883 | STKc_KSR1 |
| cd14194 | 627-843 | STKc_DAPK1 |
| cd14143 | 625-885 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd06625 | 626-871 | STKc_MEKK3_like |
| cd09549 | 910-978 | SAM_EPH-A10 |
| cd08229 | 599-883 | STKc_Nek7 |
| cd06626 | 627-833 | STKc_MEKK4 |
| cd14082 | 624-821 | STKc_PKD |
| cd14196 | 623-839 | STKc_DAPK2 |
| cd07833 | 626-824 | STKc_CDKL |
| cd14105 | 627-839 | STKc_DAPK |
| cd05581 | 622-850 | STKc_PDK1 |
| cd14208 | 627-881 | PTK_Jak3_rpt1 |
| cd07856 | 625-850 | STKc_Sty1_Hog1 |
| cd14191 | 623-837 | STKc_MLCK1 |
| cd07832 | 678-820 | STKc_CCRK |
| cd14006 | 627-850 | STKc_MLCK-like |
| cd06608 | 625-877 | STKc_myosinIII_N_like |
| cd14161 | 625-850 | STKc_NUAK2 |
| cd08219 | 623-871 | STKc_Nek3 |
| pfam00041 | 437-520 | fn3 |
| cd06619 | 621-827 | PKc_MKK5 |
| cd08221 | 660-887 | STKc_Nek9 |
| cd14001 | 651-882 | PKc_TOPK |
| cd14144 | 625-883 | STKc_BMPR1 |
| cd06613 | 622-871 | STKc_MAP4K3_like |
| cd06622 | 627-878 | PKc_PBS2_like |
| cd14172 | 624-878 | STKc_MAPKAPK3 |
| cd14192 | 625-839 | STKc_MLCK3 |
| cd14142 | 610-883 | STKc_ACVR1_ALK1 |
| cd06657 | 627-849 | STKc_PAK4 |
| cd14077 | 627-829 | STKc_Kin1_2 |
| cd07858 | 627-820 | STKc_TEY_MAPK |
| cd05612 | 627-839 | STKc_PRKX_like |
| cd13983 | 657-832 | STKc_WNK |
| cd14160 | 627-881 | PK_IRAK3 |
| cd14220 | 627-883 | STKc_BMPR1a |
| cd06624 | 611-832 | STKc_ASK |
| cd07878 | 627-820 | STKc_p38beta |
| cd14106 | 627-841 | STKc_DRAK |
| cd14166 | 625-843 | STKc_CaMKI_gamma |
| cd07877 | 627-848 | STKc_p38alpha |
| cd06617 | 647-876 | PKc_MKK3_6 |
| cd13982 | 678-871 | STKc_IRE1 |
| cd07865 | 611-818 | STKc_CDK9 |
| cd14193 | 621-839 | STKc_MLCK4 |
| cd13990 | 627-836 | STKc_TLK |
| cd06618 | 615-876 | PKc_MKK7 |
| cd06607 | 627-871 | STKc_TAO |
| cd14098 | 623-878 | STKc_Rad53_Cds1 |
| cd14068 | 626-881 | STKc_LRRK2 |
| cd08223 | 625-819 | STKc_Nek4 |
| cd07864 | 626-833 | STKc_CDK12 |
| cd14175 | 623-827 | STKc_RSK1_C |
| cd14186 | 622-846 | STKc_PLK4 |
| cd14067 | 652-877 | STKc_LRRK1 |
| cd08218 | 621-877 | STKc_Nek1 |
| cd05602 | 625-870 | STKc_SGK1 |
| cd14050 | 620-826 | PKc_Myt1 |
| cd14116 | 622-847 | STKc_Aurora-A |
| cd08528 | 627-822 | STKc_Nek10 |
| cd14195 | 627-843 | STKc_DAPK3 |
| cd14176 | 622-906 | STKc_RSK2_C |
| cd06633 | 627-891 | STKc_TAO3 |
| cd06616 | 627-879 | PKc_MKK4 |
| cd14083 | 622-829 | STKc_CaMKI |
| cd05620 | 625-842 | STKc_nPKC_delta |
| cd14089 | 625-817 | STKc_MAPKAPK |
| cd14039 | 627-827 | STKc_IKK_alpha |
| cd14076 | 623-829 | STKc_Kin4 |
| cd14047 | 606-880 | STKc_EIF2AK2_PKR |
| cd14177 | 622-832 | STKc_RSK4_C |
| cd14168 | 622-887 | STKc_CaMKI_delta |
| cd14169 | 619-848 | STKc_CaMKI_beta |
| cd05604 | 625-870 | STKc_SGK3 |
| cd07880 | 625-932 | STKc_p38gamma |
| cd07857 | 622-847 | STKc_MPK1 |
| cd14184 | 622-839 | STKc_DCKL2 |
| cd05579 | 627-851 | STKc_MAST_like |
| cd14209 | 626-846 | STKc_PKA |
| cd14178 | 622-827 | STKc_RSK3_C |
| cd05582 | 625-839 | STKc_RSK_N |
| cd05574 | 622-870 | STKc_phototropin_like |
| cd14164 | 627-876 | STKc_TSSK6-like |
| cd13986 | 622-884 | STKc_16 |
| cd14189 | 651-877 | STKc_PLK3 |
| cd14046 | 625-878 | STKc_EIF2AK4_GCN2_rpt2 |
| cd14119 | 650-876 | STKc_LKB1 |
| cd14041 | 625-854 | STKc_TLK2 |
| cd06636 | 615-877 | STKc_MAP4K4_6_N |
| cd07845 | 627-820 | STKc_CDK10 |
| cd05603 | 625-870 | STKc_SGK2 |
| cd13985 | 621-882 | STKc_GAK_like |
| cd14183 | 622-817 | STKc_DCKL1 |
| cd14095 | 669-817 | STKc_DCKL |
| cd07879 | 600-821 | STKc_p38delta |
| cd07853 | 627-821 | STKc_NLK |
| cd06634 | 627-842 | STKc_TAO2 |
| cd14074 | 623-879 | STKc_SNRK |
| cd05570 | 626-870 | STKc_PKC |
| cd14198 | 627-841 | STKc_DRAK2 |
| cd14133 | 622-848 | PKc_DYRK_like |
| cd14040 | 625-836 | STKc_TLK1 |
| cd14093 | 664-828 | STKc_PhKG |
| cd07862 | 627-853 | STKc_CDK6 |
| cd07836 | 621-839 | STKc_Pho85 |
| cd13988 | 627-827 | STKc_TBK1 |
| cd05592 | 625-827 | STKc_nPKC_theta_like |
| cd14114 | 623-827 | STKc_Twitchin_like |
| cd14179 | 679-827 | STKc_MSK1_C |
| cd06635 | 627-842 | STKc_TAO1 |
| cd14188 | 663-877 | STKc_PLK2 |
| cd05611 | 627-840 | STKc_Rim15_like |
| cd14087 | 623-829 | STKc_PSKH1 |
| smart00060 | 436-517 | FN3 |
| cd14187 | 646-878 | STKc_PLK1 |
| cd07852 | 660-818 | STKc_MAPK15-like |
| cd05630 | 625-827 | STKc_GRK6 |
| cd14153 | 621-883 | PK_KSR2 |
| cd13993 | 622-816 | STKc_Pat1_like |
| cd14012 | 676-871 | PK_eIF2AK_GCN2_rpt1 |
| cd14091 | 623-827 | STKc_RSK_C |
| cd07860 | 622-821 | STKc_CDK2_3 |
| cd07838 | 627-818 | STKc_CDK4_6_like |
| cd14131 | 621-871 | PKc_Mps1 |
| cd07831 | 627-848 | STKc_MOK |
| cd14070 | 623-827 | STKc_HUNK |
| cd06615 | 664-826 | PKc_MEK |
| cd09542 | 915-972 | SAM_EPH-A1 |
| cd05619 | 615-842 | STKc_nPKC_theta |
| cd05601 | 623-827 | STKc_CRIK |
| cd06650 | 664-826 | PKc_MEK1 |
| cd07850 | 625-818 | STKc_JNK |
| cd14197 | 678-841 | STKc_DRAK1 |
| cd14085 | 651-829 | STKc_CaMKIV |
| cd05572 | 627-827 | STKc_cGK |
| cd06637 | 625-901 | STKc_TNIK |
| cd05593 | 625-870 | STKc_PKB_gamma |
| cd14180 | 679-827 | STKc_MSK2_C |
| cd14109 | 665-827 | PK_Unc-89_rpt1 |
| cd07863 | 627-819 | STKc_CDK4 |
| cd06655 | 627-898 | STKc_PAK2 |
| cd14181 | 661-828 | STKc_PhKG2 |
| cd14665 | 627-829 | STKc_SnRK2-3 |
| cd06656 | 627-898 | STKc_PAK3 |
| cd06647 | 604-827 | STKc_PAK_I |
| cd14117 | 614-849 | STKc_Aurora-B_like |
| cd05573 | 625-867 | STKc_ROCK_NDR_like |
| cd06652 | 622-828 | STKc_MEKK2 |
| cd07871 | 621-826 | STKc_PCTAIRE3 |
| cd14104 | 623-839 | STKc_Titin |
| cd05615 | 626-834 | STKc_cPKC_alpha |
| pfam00041 | 326-421 | fn3 |
| cd07861 | 621-826 | STKc_CDK1_euk |
| cd14088 | 625-834 | STKc_CaMK_like |
| cd07854 | 650-821 | STKc_MAPK4_6 |
| cd07846 | 626-824 | STKc_CDKL2_3 |
| cd14170 | 695-828 | STKc_MAPKAPK2 |
| cd05616 | 626-849 | STKc_cPKC_beta |
| cd07874 | 627-890 | STKc_JNK3 |
| cd14048 | 625-854 | STKc_EIF2AK3_PERK |
| cd05631 | 625-841 | STKc_GRK4 |
| cd06638 | 622-871 | STKc_myosinIIIA_N |
| cd05632 | 625-827 | STKc_GRK5 |
| cd05595 | 625-870 | STKc_PKB_beta |
| cd05585 | 626-850 | STKc_YPK1_like |
| cd14182 | 679-828 | STKc_PhKG1 |
| cd05613 | 625-827 | STKc_MSK1_N |
| cd14157 | 627-821 | STKc_IRAK2 |
| cd14096 | 622-829 | STKc_RCK1-like |
| cd06649 | 664-826 | PKc_MEK2 |
| cd06653 | 622-828 | STKc_MEKK3_like_u1 |
| cd06654 | 627-827 | STKc_PAK1 |
| cd14113 | 631-846 | STKc_Trio_C |
| cd05607 | 625-829 | STKc_GRK7 |
| cd14219 | 610-883 | STKc_BMPR1b |
| cd14185 | 662-848 | STKc_DCKL3 |
| cd14049 | 610-839 | STKc_EIF2AK1_HRI |
| cd07872 | 621-821 | STKc_PCTAIRE2 |
| cd14078 | 623-820 | STKc_MELK |
| cd14662 | 627-829 | STKc_SnRK2 |
| cd06645 | 625-887 | STKc_MAP4K3 |
| cd14115 | 627-871 | STKc_Kalirin_C |
| cd14086 | 622-848 | STKc_CaMKII |
| cd07873 | 621-826 | STKc_PCTAIRE1 |
| cd13995 | 669-878 | STKc_MAP3K8 |
| cd09544 | 914-974 | SAM_EPH-A3 |
| cd08226 | 677-830 | PK_STRAD_beta |
| cd05589 | 626-846 | STKc_PKN |
| cd05590 | 625-842 | STKc_nPKC_eta |
| cd05575 | 626-870 | STKc_SGK |
| cd07839 | 622-826 | STKc_CDK5 |
| cd14199 | 670-876 | STKc_CaMKK2 |
| cd14004 | 623-878 | STKc_PASK |
| cd13991 | 621-870 | STKc_NIK |
| cd14141 | 679-821 | STKc_ACVR2a |
| cd06651 | 625-828 | STKc_MEKK3 |
| cd14031 | 660-832 | STKc_WNK3 |
| cd05599 | 626-827 | STKc_NDR_like |
| cd07876 | 627-820 | STKc_JNK2 |
| cd06639 | 623-871 | STKc_myosinIIIB_N |
| cd05577 | 627-827 | STKc_GRK |
| cd07869 | 622-820 | STKc_PFTAIRE1 |
| cd14033 | 621-870 | STKc_WNK4 |
| cd14094 | 620-849 | STKc_CASK |
| cd07847 | 627-828 | STKc_CDKL1_4 |
| cd14036 | 621-880 | STKc_GAK |
| cd07875 | 627-874 | STKc_JNK1 |
| cd08216 | 631-830 | PK_STRAD |
| cd07848 | 626-819 | STKc_CDKL5 |
| cd05614 | 625-827 | STKc_MSK2_N |
| cd14107 | 619-858 | STKc_obscurin_rpt1 |
| cd05571 | 625-834 | STKc_PKB |
| cd05594 | 604-846 | STKc_PKB_alpha |
| cd14200 | 670-829 | STKc_CaMKK1 |
| cd14163 | 622-829 | STKc_TSSK3-like |
| cd13987 | 627-828 | STKc_SBK1 |
| cd05591 | 625-847 | STKc_nPKC_epsilon |
| cd05623 | 622-828 | STKc_MRCK_alpha |
| cd07870 | 627-820 | STKc_PFTAIRE2 |
| cd05624 | 622-828 | STKc_MRCK_beta |
| cd14092 | 624-827 | STKc_MSK_C |
| cd05584 | 625-827 | STKc_p70S6K |
| cd14051 | 626-871 | PTKc_Wee1 |
| cd14118 | 670-870 | STKc_CAMKK |
| cd07842 | 622-822 | STKc_CDK8_like |
| cd05586 | 627-839 | STKc_Sck1_like |
| smart00060 | 325-414 | FN3 |
| cd13416 | 252-378 | TNFRSF16 |
| cl22855 | 252-378 | TNFRSF superfamily |
| cd00185 | 255-322 | TNFRSF |
| cd13410 | 269-327 | TNFRSF9 |
| cd15834 | 244-321 | TNFRSF1A_teleost |
| cd13419 | 257-321 | TNFRSF19L |
| pfam07714 | 621-880 | Pkinase_Tyr |
| smart00454 | 910-977 | SAM |
| smart00219 | 621-880 | TyrKc |
| smart00221 | 621-880 | STYKc |
| smart00220 | 622-878 | S_TKc |
| pfam00069 | 622-878 | Pkinase |
| COG0515 | 622-947 | SPS1 |
| PLN00034 | 627-818 | PLN00034 |
| PTZ00263 | 622-831 | PTZ00263 |
| PTZ00024 | 627-821 | PTZ00024 |
| PHA03209 | 648-822 | PHA03209 |
| PTZ00426 | 625-820 | PTZ00426 |
| PHA03212 | 663-819 | PHA03212 |
| PTZ00267 | 661-879 | PTZ00267 |
| TIGR03903 | 650-847 | TOMM_kin_cyc |
| PTZ00266 | 599-846 | PTZ00266 |
| PHA02988 | 650-880 | PHA02988 |
| PRK13184 | 623-860 | pknD |
Ontology Information
| HPRD ID | 4206 |
|---|---|
| Molecular Class | Receptor tyrosine kinase |
| Molecular Function | Protein serine/threonine kinase activity (GO:0004674) |
| Biological Process | Regulation of cell cycle (GO:0000074); Apoptosis (GO:0006915); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.