CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
EPHB4	2050	EPH receptor B4	7	HTK; MYK1; TYRO11

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
19738063	2009	Cell line : SW 837, HT 29 Source : - Sample Type : - No. of Sample : - Stage : -	Western blotting, Mouse knockout strains, Immunohistochemistry, Detection of apoptosis, qRT-PCR, Microarray	Down-regulation	-	The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis. loss of EPHB4 in colon cancer cells results in a significantly increased potential to invade through a complex extracellular matrix. EphB4 has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remoDeletionng, and invasive potential are important mechanisms of tumor suppression
16982731	2006	Cell line : - Source : Spanish patients Sample Type : Formalin-fixed, paraffin-embedded tumor No. of Sample : 125 Stage : -	Methylation-specific PCR, immunohistochemistry, Western blotting,reak time RT-PCR, Clonogenic Assays.	Methylation	-	EPHB4 as a useful prognostic marker for colorectal cancer. promoter methylation regulates EPHB4 transcription and functional evidence that EPHB4 can regulate the long-term clonogenic potential of colorectal tumor cells, revealing EPHB4 as a potential new tumor suppressor gene in colorectal cancer. We found that EPHB4 expression is frequently reduced or lost in colorectal tumors.
19366806	2009	Cell line : HT 29 Source : ATCC Sample Type : - No. of Sample : - Stage : -	Immunoblotting, Transfection, sorting and invasion assays,qPCR.	Up-regulation	-	EphB4 is preferentially induced in colorectal cancer, in contrast to EphB2, whereby tumor cells acquire a survival advantage. Gain of EphB4 provides survival advantage to tumor cells and resistance to innate tumor necrosis factor-related apoptosis-inducing ligand-mediated cell death. Knockdown of EphB4 inhibits tumor growth and metastases.
21852108	2012	Cell line : LIM 1215, CaCo 2, LISP 1, LoVo, HCT 116, and HT 29 Source : - Sample Type : - No. of Sample : - Stage : -	Flow cytometry, Western blotting and immunocytochemistry, real time RT-PCR, In vitro demethylation.	Up-regulation	-	EphA1, EphA2, EphB2 and EphB4 were significantly over expressed in CRC.
23211050	2012	Cell line : HT 29 Source : ATCC,Female athymic nude mice (BALB/c nu/nu), from Harlan (Indianapolis, IN). Sample Type : Mouse model No. of Sample : - Stage : -	SDS-PAGE and Gel Infrared Imaging, Binding Activity Assay, Binding Function Assay, Cell Culture	Up-regulation	-	EphB4 plays key roles in cancer progression in numerous cancer types.
23579861	2013	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	RT-PCR	Up-regulation	-	EPHB4 constitutes a potential predictive biomarker. Determination of EPHB4 levels in CRC samples could be useful for the prediction of response to bevacizumab.

Gene Details

Chromosome: 7; NC_000007.13 (100400187..100425143, complement)
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Gene Type	protein coding
Gene Family	EPH receptors, Sterile alpha motif (SAM) domain containing, Fibronectin type III domain containing
Description	Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008]
Chromosome	7
Location	7q22
Start	100802565
End	100827521
Strand	-
Gene Sequence	>gi\|568815591:c100827521-100802565 Homo sapiens chromosome 7, GRCh38.p2 Primary Assembly TTCCAGCGCAGCTCAGCCCCTGCCCGGCCCGGCCCGCCCGGCTCCGCGCCGCAGTCTCCCTCCCTCCCGC TCCGTCCCCGCTCGGGCTCCCACCATCCCCGCCCGCGAGGAGAGCACTCGGCCCGGCGGCGCGAGCAGAG CCACTCCAGGGAGGGGGGGAGACCGCGAGCGGCCGGCTCAGCCCCCGCCACCCGGGGCGGGACCCCGAGG CCCCGGAGGGACCCCAACTCCAGCCACGTCTTGCTGCGCGCCCGCCCGGCGCGGCCACTGCCAGCACGCT CCGGGCCCGCCGCCCGCGCGCGCGGCACAGACGCGGGGCCACACTTGGCGCCGCCGCCCGGTGCCCCGCA CGCTCGCATGGGCCCGCGCTGAGGGCCCCGACGAGGAGTCCCGCGCGGAGTATCGGCGTCCACCCGCCCA GGGAGAGTCAGACCTGGGGGGGCGAGGGCCCCCCAAACTCAGTTCGGATCCTACCCGAGTGAGGCGGCGC CATGGAGCTCCGGGTGCTGCTCTGCTGGGCTTCGTTGGCCGCAGCTTTGGAAGGTGAGTTTCCTTGCGGG GGGGGGCGCACCCCGTCACTCCTGGGACCTCCCCCCCAACATCTGGGCCTCGGAGTGGAGGGGCCGGCCT CTGACTACCCCTACCCGGGCACTGCAGTCCCAAACACTTCGGACCGATAGTGCTGGAACGGGAGGGGGGC GGGGAAGAGGCGCCCGACGGGTAGTGGAGTTTTCTTTTGTTTGGGAAAGAGATGGAGTCTGGCTACGACC CGGGACATTCCCCTGCCCGGGCTCCCCGAACTCTCACTGCTGATTACATACGCCCCTGGCTGCCTTTCCT TTCCTCCCTACCCCACTATTCAAAACTATCTGCAAAGTTTCTGTCCCAGTCCCACCTCCCGCCGTACATG AGGGAAGGTTTCTGGAGAAGCAACAGCAGACAAGGCACAACTTTTCGTGCTAGGCCCTAAAACGACCCCC AGCGCCAATTCCTTAGCGATCACACCTTGATCCTCCAGTTCCACACTCCTGCAACAGGATGGCCTCCTTT GCATTCACACAGCAAACCCCCAAACCGCTCTCCCGCCCACTGCTCCTGCCCCTGGTATAGGGTGGCTCCT TGGTTTCTACAGGCTGCACCCCATCCCTTTAAATGCGGTCTAGACCCCGGCCCCAGGTGAGTCCCGGGCT TCCCTTGAGACCTAGGAGCGGGTAGAAACTGACCTACACAGCCCCCAGGTAGAAACTGACCTACACAGCC CCCACATCGCCCTAACTAACCCAGTCTATCTCCCACCTCCTGGTCTCTCCAAGCATTTCTTTGGCCATGG ATCGCTGTCCCTCCTGGTCCCCTAAAGGGGGAGCCAAGAGCCCTAGAAACTCTCCTGTGTCCCTAATGTC CTTTCAGTGAGCTGCCAACACCCCCCTTTCTCTGTCTGGTATGAAAGTGGTTATGGGGCGGTAGGCTATG AGGGACTCCCAAAGGGAAGGATTCAGCGGCGTTAGAAAAACCCTCTCCCCCTGGCTGGGCAGGACTGCCC TGGGCTGGGGATCAAAGGCTAGGTGTGGGGTTGGGAGTGAGGGGAGGCTTGCCCAGCTCAGAGAACGGAG AAGGGGGAACAAAAACCATGAACGAGGGGAAGAGGAAGGCCAAAGGGGTGGAAAAACCACGAGGACGAGG TGTGGTGAGAAGGAAAGACGCAAAGAGGAAATGGTGATTGTGACACCTATTACCTGAGTGTTTCCAAGCA CCAGGCCTGTGCTGAGCGCCTTACAAATATTAATTTCACCCATCCAGCAACGCTAAGGGTGGTGCTATTA TTGCCCCCATTTTTCAGATGAGGAGGCTGGGGCTTAGTTAAGGTTAAGTAGTTTATCCAAGGCCCTGTGC CGCGAGGAACAGCGAGAAGTGGAGGCCGAAAGCGAAGGAGAGATAGTGACTGTCAGAAAGAGAAACGGAG GTGGACAGAGAGTGGAGGAGAGATAGGTGAGAGACATGCGAACTGACAGATCAAAGCGTGGCTGCAGCTG AGCTGGGACGCAGAAAGGGAGCCTGCGCTTGCTCTGGGCTGCGGACAGCCCGAGGCAGAGACAGTGTGTA AATTGGAGACAGGAAAACACTATCCCGGCTGGAACAATGGAGGGTGGAGACGGCAGCCTCTATCCACCCC CTTCCCAGAACCCGGGCATCCTGTCCCCAGTGAGCAGGGCTGTCTCTTGCCACCCATGGGGACCTTGCGC CTCTCACCTCAGGCTGGCTGGCTTCCCATCTGACCCCTAGCTGGAGGACATCATTTGGTCCCCAGGAAGA GGCTGCCTCACCCACCCTCTTTCTCTTCTCTCCTGCAGCTCCCATGGGGTGGGAGCCAGGTGTTCTGGCT CCCCTCTCCACCCTTCCCAGCGCCCAATGCCCCCCACATTGCCGGCCCCCGAGGGGATTCCTGTACCCTC CCTCCTCCACTCTCCACTGCCAGGGGCTGTGCAGTTTTTCCTAATCCCCCCCCTTCCTCCAGTGCCTGTC CCCTCCCCCGATGATCCGAGCCAAGCCAGGTGTGTTCACCCCTCCCATTCATACCGCCCCCCAGAATCTC CTCCCCTCTGCCTTCCCATAACCAAATCCAGATGTGAGGCCTCGGCGGGAGCCTGGGAACCCTAGCATCC CGACCTCCAGTGCTTCCTGATCAGGGCACTCGTGGGGAGGGAGGTACTGGGATGGGGGCCAGGGCTATGC CCCAGGCACGGAGCGCTCCCTTCAAGGAGGGAAGGACGGGGTGTTTGGTCTGAAAGCAGAGAGGGGTCTT GGACAGGGAATGAAATTGTGGGGTAGAGAGGCTGATTCTGGGACTTAGGGGAGGAAACGTGGAGGCTGAG ACAAGAGGTTCCCCTCCCACACCAGCAGCCTCTGCTCGTGGGGGTCAGGACCAGGGCGCAGCTCTCATTT TAACCCTTTCTGAGCTGCCGCCCCTTCTCCCCGTACATTTTGATCTCCCTCCCTCCTCCAGGGAGGCCTA GATCTGGGGTATCCCAAGGGAGCCCCATGCCTACCAGATGTTGGGGGTGGGGTTGGCACTTAGCAGAAGA GGCCAGAAATCAGGCGGGTGCAGAGGGCAGGGCTTGCTCCCCTCTTGGCCCCCCAACTCCTCTAGCTCAG AGCTAAGAGGATCCACCTGCCTCGGTTCCCAGGGATCTGGTCTTCCTGACCTCCCTCCCCCACCCCAGGC ACTGACTCTGTCTCTCTGTCTGTCTCAGAGACCCTGCTGAACACAAAATTGGAAACTGCTGATCTGAAGT GGGTGACATTCCCTCAGGTGGACGGGCAGGTGAGAGCTGCACCCAGGAGCTGGAGCTCTGGAGGGAAACT GAGGGAGGAGAGGGCGCCTGTGCCGCCTGCTTTCTGTGTGCCACTCCTCTCCCCTGTCCCCCCAGATGAC AGCAGCCCCAGCAGTGTCGTCTGAGCCCTTCTCAGAGGCGCCCTCCTCGCAGTACCAGCAGCCCCCCTTT CTCAGTCCCTCTCACTTTATAGGATTCACCCCATGCAGCCCTCTCCCTGGCGGCTCCCCAGCCCCCTTGC TGACCTCCTTCTCTGCACAGTGGGAGGAACTGAGCGGCCTGGATGAGGAACAGCACAGCGTGCGCACCTA CGAAGTGTGTGACGTGCAGCGTGCCCCGGGCCAGGCCCACTGGCTTCGCACAGGTTGGGTCCCACGGCGG GGCGCCGTCCACGTGTACGCCACGCTGCGCTTCACCATGCTCGAGTGCCTGTCCCTGCCTCGGGCTGGGC GCTCCTGCAAGGAGACCTTCACCGTCTTCTACTATGAGAGCGATGCGGACACGGCCACGGCCCTCACGCC AGCCTGGATGGAGAACCCCTACATCAAGGTACCTGGGTGCCCCCAGGGCTCAGCCACAGCCAAGGTGGGA TTCCAGCCAGCAGGCCCGTGGCCTGGAGGGCAGCCGATGTAGTTGCGAGGCCTCTGGCCCGCGCGCTGGG GGCTGGAAGCAGGAGGCTTAGGTCTGGGGAGGGAAGGGGGTGATCTTCTGGGCGGAGGAGCAGAATATAC GGGGGCTGCCTGGCCCGGCCCCCAGGGAGGCCCAAGGGTCAGGCTTCTCCTCCAGTCACCTCAACCACCC TACCCCACTGTGCTCCAGCCACACTGAGTTTCTCCCATTCCCTGACTGCACCTGGCTGGTTTCCAGCTCA AGACTTTGCAGCGGTGATGTCTCCACCTGGGGGCCTCTCTGCCTCTCACACCCCTACTTGTCTTCGGAGT TCCAGCTCCCGAGATCTTGCCTGTGCCACCTTGGCTGACTCTCTCCTCCCTACAATCCTGCATACCTCTG TCCACCTGCCTGTCTCGGCACTCATTTTACTTTATTTATTTTTCTTTTATATCTATATTTTTAAAGCGGG GTCTTCTACGTTACCCAGGCTGGTCTCTAACTCCTGGGCTCAAGAGATTTCTCCCACCTCGGCCTCCTAA AGTGCTGGGATTATAGGCATGAGGCACTACGCCCGGCCTCATGGTACTTTATAACTTCCCCAGGATTCAT TCATCGCTGTCTCCTTGACTCTGAGGTCAAGGCCTGGCATGGCGTCAGTGTCAGTAAATGTTTGTAGAAC GAGTGAATAAAAAGGGGGAGAGGTGCAGGCCAGAGGCCGGGCATATCGCAGGAGCTTTGCAAGGCTGAAT GGACAGTGTGGGGGCCTGCAGAAAGTGTGCCCTGGGGAAGGTGGAGGGAAGATTCTGGAACGGGAACCAA GGAGGTCCGGGAGGGTGAGCTGGGAAGAACACAACAGTCCGCTGGGTCCTCAGGGAGTGGGGACAGCAGC GGTGTGCCTCCCCCCCGCCGGCAGGTGGACACGGTGGCCGCGGAGCATCTCACCCGGAAGCGCCCTGGGG CCGAGGCCACCGGGAAGGTGAATGTCAAGACGCTGCGTCTGGGACCGCTCAGCAAGGCTGGCTTCTACCT GGCCTTCCAGGACCAGGGTGCCTGCATGGCCCTGCTATCCCTGCACCTCTTCTACAAAAAGTGCGCCCAG CTGACTGTGAACCTGACTCGATTCCCGGAGACTGTGCCTCGGGAGCTGGTTGTGCCCGTGGCCGGTAGCT GCGTGGTGGATGCCGTCCCCGCCCCTGGCCCCAGCCCCAGCCTCTACTGCCGTGAGGATGGCCAGTGGGC CGAACAGCCGGTCACGGGCTGCAGCTGTGCTCCGGGGTTCGAGGCAGCTGAGGGGAACACCAAGTGCCGA GGTGAGAGCTGGAGCTTCCCCTGCGACTGCTGCTCATCCGGGGGAGAGTCCTGAACTCCACTCAGGACCC ACTTCTTAAGTTTCCATTTTGTATAGTTAGATGTTGAAATGGAGGCTTGCTCTGTCACCCAGGCTGGAGT GCAGTGGCACAATCTCTGCTCAACTGCAACCTTTGCCTCCCGGGTCCCTGTTCAAGCAGTTCTCCTGCCT CAGCCTCGTGAGTAGCTGGGACTACAGGCACACGCCACCACGCCCGGCTAATTTTTGTATTTTAGTAGAG ACGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTGAAGTGATTTGCCCGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCGTGCGTCACCACACCCAGCTGGAAAAAAAAAAGACTTTATTTTCACC TGAAATTCATTAATTTCCACTTGAAATTCCACCTGCAGTTGTAGCAGGACCTGACACTTGGGCCCCATGG AAATCACAGGTATTGCCTGACACAGTGGTTCATGCCCATAGTGCCAGCACTTTGAGATGCCAAGGTGGGA GGATCACTTGAGCCCAGGAGTTCGAGATCAGCCTGGGTGACAGAGCAAGACCCCGTCTCTAAAAAAAATT TTTTTTTTTTTTTCAAGACAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTC ACTGCAAGCTCCGCCTCCCAAGTTAACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGG CCCCGCCACCACGCCCGGCTAATTTCTTGTATTTTTAGTAGAGATGGAGTTTCACCGTGTTAGCCAGGAT GGTCTCGATCTCCTGACCTCATGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGC CACCACACCCGGATTACAAAAACTTTTTAGATAATTATCTGGGCGACCTGCCTGACCAACATGGAGAAAC CCTGTCTCTACTAAAAATACAAAATTAGCCGGACATGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGA GGCTGAGGCAGGAGAATCATTTGAACCCAGGAAGCAGAGGTTGCGGTAAGCCGAGATCATGCCACTGCAC TCCGGTCTGGGAGTGCACTCCAACAAGAAGGAGTTTCGCTCTTTTTGCCCAGGCTGGAGTGCAGTGGTGG GATCTCAGCTCACCGCAACCTCCACCTCCCGGGTTCAGGCGATTCTCCTGCCTCAGCCTCCCAAGGAGTA GCTGGGATTATAGGTATGCATCGTCACACCCGGCTACTTTTGTATTTTTAGTAGAGGCAGGTTTCCACCA TGTTGGCCAGGCTGGTCTTGAACTCAAGTGATCTGCCCTCTTTGGCCTCCTTCTCAGGAAAAAAAAAAAA TCACAGGTATTTACAGGCCATTCCAAGTGCCAAAAGATTGTTTTTGCTCATGGTGACTTCAGTATCACAG ATGTTAGGAGACTTGCTGCTATATGTTAAGAAAGAAGCACAAATGTTGCTGTAGCCCAAACTTTTTTCCT CATGTTTCATTGCATTTCAGCTTAATTGGTTTCCCTGGTATTCCTATGTATTTTGTGGAGTGCTTTTAAA ATCATAAGTTGGAGTAGAGGTCTTTCTGTGGGCTTCACCAGACTGCCGAGATCAGGGTCGAAACAGGTGA GGACCCCTTCTCTGGAGAGAGTCTCCTTTCTCCTCTAAGAGGAAAGGTTTTGAGATCTTTTGTCCATTTT CCCACCTTAGCACTTCATCAGCCTTAAAAGAAGCTGGAATTTTTTTTTTTTTTTTTGGAGATGGGATCTC GATATGTTGCCCAGGCTGGTCTTGAACCCCTTGGCTCAAGCGATCCTCCAGCCTCAGCCTCCCAAAGTGC TGGGATTCGAGGCATGAGCCACCGAGCCCACCGTGCAGATGGATGTTTTTGTGCATGCTTTTGATGAATG CTTTCTCTCTCTCAGCCTGTGCCCAGGGCACCTTCAAGCCCCTGTCAGGAGAAGGGTCCTGCCAGCCATG CCCAGCCAATAGCCACTCTAACACCATTGGATCAGCCGTCTGCCAGTGCCGCGTCGGGTACTTCCGGGCA CGCACAGACCCCCGGGGTGCACCCTGCACCAGTAAGTGACCAGCACCCAGGTGCAGTTCACTGGGGAGGG GTCACAGACCTCTGAGGTGGACCCTCACATGGCCCCCATCCTCCCTGGGCTTCTTCCCTTTGTCCCTGGC ATGCTTGTCCCTAGCCCGGAGGAACATGTGGAGCCCACTGTCTCCAAGGCAAGAGTCCAGCATGGCTGCT GGTGCCTCCATTGCCCTCTCCCCACCACCGCAGAGCAGGTCGGCCTCTGCCTGACTCCCTGGTCTCCTGC AGCCCCTCCTTCGGCTCCGCGGAGCGTGGTTTCCCGCCTGAACGGCTCCTCCCTGCACCTGGAATGGAGT GCCCCCCTGGAGTCTGGTGGCCGAGAGGACCTCACCTACGCCCTCCGCTGCCGGGAGTGCCGACCCGGAG GCTCCTGTGCGCCCTGCGGGGGAGACCTGACTTTTGACCCCGGCCCCCGGGACCTGGTGGAGCCCTGGGT GGTGGTTCGAGGGCTACGTCCTGACTTCACCTATACCTTTGAGGTCACTGCATTGAACGGGGTATCCTCC TTAGCCACGGGGCCCGTCCCATTTGAGCCTGTCAATGTCACCACTGACCGAGAGGGTGAGACTTGGGGGC TGGGGCGGCTGGTGGTCTGGCGGGAGAGATGTCACTGAGGGCCTGAAGGGGAGAGGCAGGGGCTGTGAAG TTGGGTACCCCGGAAGTGTGAGGGGCTAAGGCTTTGGGGGCAAGAGGCAGAAAGAGGGCAATGGCTGGGC GCAGTGGCTCACGCCTGTAATCCCAGCACTTTCAGAGGCTGAGACAGGCGGATCACTTGAGCCCTGGAGT TCAAGACCAGCCTGGGTAACATAGGAAGATCTCTCTACAAAAAATAAAAATATTAGCCAGGCGAGGTGGT GCATGCCTGTGGTCCCAGCTACTCAAGAGGCTGAGGCAGGAGGATTGCTTGAGCCCAGGAGTCGGAGGCT GCAGTGAGCTATGATCGCACCGCTGCATGCCAGCCTGGGTGACAGAGCAGTGTGAGATCCTCTCTCAAAA TAAATGAATAAGAAAGAGAGGGTGAGGAGCTCGTAAAGCTGGGCTGGAGAGTTAAGTACAGGAAGGCCCC CAGTGGGACTGGGGCCAGAGAGAATCAGAAGGAATTCTCGAAACAGCCAGGGGGAAATTGAGACAAGTGT AGCCAGCAGAGGAAGTGTTGGAAAAGATAAGGGACATGGCCAGGCTGATCACAAGGTCAGGAGTTCAAGA CTAGCCTGGCCAACGTGGTGAAACCCCATGTCTACTAAAAATAAAAAAATTAGCCAGGCATGGTGGTGGG CACCTGTAATCCACTTGGGAAGCAACCAGAAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTAAGCT GAGACTGCGCCACTGCACTCCAGCCTGGGTGATAGAGCACGACTCCGTCTCGAAAAAAAAAATTTTTTTT AAGTTAAGGGACAGAGCTACCATGCACAAGGGTTCCCTGTGTCTCTGCCTCTCACAGTACCTCCTGCAGT GTCTGACATCCGGGTGACGCGGTCCTCACCCAGCAGCTTGAGCCTGGCCTGGGCTGTTCCCCGGGCACCC AGTGGGGCTGTGCTGGACTACGAGGTCAAATACCATGAGAAGGTAAGGCCATCCCCCAGCCCTGGGGTGG GTGGGCAATGGGTTGTGCTCTCCTGGCTGGGACACCTGGGTTGCAGGCACCTGGCAGGCATTTGAATTCC AGCTCTGCCATGGATTCCCTGGGCAGCCTTGGGTAAGCCCCTTGGCCTGTCTGAGCCTCAGACTCTTCAT CTATAAAATAGTTACTGTAATAGTTACCAGCAGCTGGACACAGTGGCTGAGGTTGGGTGCGGTGGCTCAC GCCTGTAATACCAAGCACTTTGGGAGGCTGAGGCGGGCAGAATGCTTGAGCCTAGGAGTTTGAGACCAGC CTGGGCAACATGGTGAAACTTCATCTCTATAAAAAACTTAAAATGGGCCGGGCGCGGTAGCTTACGCCTG TAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACAAGGTCAGGAGTATCGAGACCATCCTGGCTA ACACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGGCGCGGTGGCAGGCGCCTGTAGTC CCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGA TAGCGCCACTGCAGTCCGGCCTGGGCGAAAGAACAAGACTCTGTCTCCAAAAAAAAAAAAAAAAAAAAAA AACGCAAAAAATACTTAAAATGAAAAAAATTAGACTGGGCACAGTGGCTCATGCCTGTAATCCCGGCACT TTGGGAGGCCGAGGTGGGTAGAACACCTGGGGTGAAGAGTTCGAGACCAGCCTGGCCAACAAGGTGAAAT CCCCGTCTCTACTACAAATAGCAAAATCAGCTGAGTGTGTTGGCGGGCCCCTGTAATCCCAGCTACTCAG GAGGCTGAGACAGGAGAATCACTGGAACCCAAGTGATTCTCGACTTGAGGTCGAGGCTGCAGTGAGTCGT GTTTGCACCATTGCATTCCAGCCTGAGAAAGTGAGACCTTGTCTTAAAAAAAAGGAATGATATTATGAAT ACAGCACATGGCTTGCATGCGTAAGTTCTCCCAAAGGCCTCACCAGTTGCAAGGCAGGCTAGTGATGGGA GTGGAGGGCGAGGGAAGGAGGCAGGAAGAGCAACAGGAACTTGGGTTCCCGGGTGACGGCCACCCCACTA CCTCTCCCGGACAGGGCGCCGAGGGTCCCAGCAGCGTGCGGTTCCTGAAGACGTCAGAAAACCGGGCAGA GCTGCGGGGGCTGAAGCGGGGAGCCAGCTACCTGGTGCAGGTACGGGCGCGCTCTGAGGCCGGCTACGGG CCCTTCGGCCAGGAACATCACAGCCAGACCCAACTGGATGGTGAGCCTGGGGAAGGGGGTGAGGGTGGGG GTTGGAAAGACCCCCAAAGTTCCTGGGAAGACCCCAGGTCTCCAAAGTCCCATCATCTTTTTTTTTTTTT TTTTTTTTTGAGATGGAGTCTTGCTCTGTCCCTCAGGCTGGAGTGCAGTGGCACCATCTCCGCTCACTGC AACCTCCGCCTCCCGGATTCAAGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCGCCT GCCACCGCGCCTGGCCGATTTTTTGTATTTTTAGTAGAGACGGGGCTTCACCGCGTTGGCCAGGCTGGTC TCGAACTCCTGACCTTGTGATTCGCCCGCCTCGGCCTCCCGAAGTGCTGGGATTACAGGCATGAGCCACT GCACCCGGTCAAAGTCCTATCTTCATGTCCTTCTTCCTGTGGATCACATGGCATGCCCTAGAGAGGAGAG AACGTAAGATGTCGAAACCAAAACCAACAGCTGAGTTTTGTGAAGTCTGGCCTGCTTCACTCTGTACCCC CAGGCTGGAGCGCAGTTGCTCGATCAAAGCTCACTGCACAGCCAGGCACAGTGGCTCACCCTGTAACCCC AGCACTTTGGGAGGCTGAAGCAGGAGGATCACTTGAGGTCAGGAGTTCGAGACCAGTCTGACCAGCATGG TGAAACCGCGTCTCTACTAAAAATATAGAAGTTAGCTGAGCGTGGTGGTGCACACCTGTAATCCCAGCTA CTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGTGCC AGTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAGCTCACCGCAGGCTTGAC TTTTAGCAACAACCTGACCCCTGAGCTCCCCATTCCCCATCCAACAAAATGGGAATATCATGAAGCTTCC TGCAGGGCTTTGAGGATTGGAGGTAACAGGTTATTTTTAATATGCTAGGCCAGTGGCTTTCTTTTTTCTT TCACATTTTTTTTTTTGAGACGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCGGTGGCGCGATCTCAGC TCACCGCAAGCTCCACCTCCTGGTCTCGATCTGCTGACCTCCTGATCCACCCGCCTCGGCTTCCCGAAAT GCTGGGACTGCTGGCGTGAGCCACCACGCCCGGCCTAACTTTTTCTTTTTTTTAAGAGACACGGTCTTTT TTATCACCCAGGCTGGAGTGCGGTGGCACCATCATAGCTCATTGCAGCCTACAACTCCCGAGCTCAACCA ATCCTTCCACCTTAGCCTCCCAAGTAGCTGGGGCTATAGGCATGTGCTACCGTGCTCAACTAAATTTTTT TTTATGTTTTGTTGAGACAGTTTCCCTATGTTGCCCAGGCTGGTCTCAAATTCCTGACCTCGAGCAATCC TCCCGCATCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCCACACCCAGCATTGGACCAGTGGC TTTCTAAACCTTGTAATTTTCTGTAATAGCTTTACTGAAATACAGTTCCCCTGCCATACAATTTGCCTGT TCAAAGTGTACAATCGATGACTTTTGATACATTCACAGAATTGTGCAGTCACCACCACAAGTAATTTTGG GACATTTTCAGCACCCTCAAAAGAGACCCTATAGCCCTTAGCCATCACCCCCCACCCAGATCTTTCTGTT GCCTTAGTCCCTGGCAAGCACTAACCCACTTTCTGTCTTGAAATCTTCCAGTGTGGTCTTTTGTGACTGT TCACCGAGCAGAATGTTTTCAAGGTTTATGTATGTTGTAGTATATATCCGTGGGTTTTTTTGGTTGTGGT TTGTTTTTTGTTTGTTTTGGAAACAGGGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTTCAATTAC AGCTCACTGCAGCCTCAACCTCCCAGGCTCAAGTGATCCTCCCACCTCAGCCTCCCAAGCAGCTGGGACT GTAGGCATGAGCCACCATGCCCAGCTAATTTTTTTTGGTATTTTTTGTAAAGACAGGGTTTCACCATGTT TCCCAGGCTGGTCTCGAACTCCTGAGCTCAGGCAATCCACCCACCTCAGCCTCCCAAAGTGCTGTGATTA CAGGCATGAGCCACTGGACCTGGCCTGTTTTTTGTTTTTGTTTTGAACACACGATTTTGCTTTGTCACCC AGGCTGGAATGTAATGGTCTGATCATAGTGCATTGCAGCCTCAAACTCCTGGGCTCAAGCGATCCTCCTA CCTCAGCCTCCTGAGTATCTGGGACCACACGTGCTCACCACCATGCTTGGCTAATTATTATTATTTTTTG ATAGAGACGGGGTCTTGCTATGTTTCCCAGGCTGGTCTTGAACACCTGGCCTCACACAATCCTCCCACCT CAGTATCTCAGAGTGCTGGGATTACAGGCATGAGCCACTGCTCCTGGCCAATATTTCATTTCTTTTTATG GAGACGTAATAATCAGTTGTATGGAAATAGCTGATTTTGTTTTTTATTGTATCTTTTGGTGAACATTTCA ATTGTATCGACTTTTTGGATAAAAACCTGAAAATGTTTCACCTTTAGAACGTTTCATTGAATGGAGATTT TTTTGTGGACTCTGGTATTTATACTAGAACCAAATCAAAACCACTCTGGCGGCTGGGCATGCCTAGGCTG GTTTGAGACTAGCCTGTCCAACCTGGTGAAAGCCCATCTCTACTAAAAATACACAAATTAGCCGAGCATG GTGGTACACACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCAGAACCCGGGAGGCGGA GATTGCAGTGAGCTGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTGCGTCTCAAAAA AACAAACAAAAAATTACTCTGGCAGTAAGAAAAGATTTCGAAACTTCCTCCCTTGCCCTGAGGTACTTCA GAGGAGCCTGCTGGCCCCTGGGGGAGAGTTTGAAACCCACTGTTTGTTCCCTGACCTTGCCTGCTTGTGT CCTCTCCCTCCACCTGTCCCCTGTACTGGGGACCTGTTCTCAGGAGATCACAGTTCATTGCTCAAAGCCG GGGCTGGGGCCTCCTACAGGACCATCAGTTTCTCCTGATCAGCAGCCTTTCCTTCCGCAGAGAGCGAGGG CTGGCGGGAGCAGCTGGCCCTGATTGCGGGCACGGCAGTCGTGGGTGTGGTCCTGGTCCTGGTGGTCATT GTGGTCGCAGTTCTCTGCCTCAGGTAAGGGCTCTGACACCCAGAGGCCCCTGGAAGCCCTCAGTTGATGG CCACCTGCCTGGGTGCTACAGGACAAGCCTTTCTGGCTGTCCCCAGCCTCTTTTTACTTGAAATCTTCTC CAATCCCTGCTCCTTCCTTTGGTGTGTGTGCCTCATAAAGATGTGTGACTCAGTTTACCTTTTGTTCCTT TCCCATCGGCTACAGGAAGCAGAGCAATGGGAGAGAAGCAGAATATTCGGACAAACACGGACAGTATCTC ATCGGACATGGTGGGTTGCCCTAATTTGATGGGAATAGGGGCTTGGGGCCGGGTGTGGTGGCTCCTATCT ATAATCCCAGCACTTTGGGAGGCAGAGGTGGGCAGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGC CAACATGTTGAAACTCCATCTCTATAAAAAATACATCAGTCAGCCAGGCATGGTGGTGGGCACCTGTAAT CCCAGCTACTCAGGAGGCTGAGGCAGAAGAATCATTTTAACCCGGGAGGCGGAGATTGCAGTGAGCCAAG ATCGCGCCACTGCGCTCCAGGCCTGGGTGACAGAGCGAGACTCCATCTCAGGAAAAAAAAAAAAAAAAAA AAAAACCACGGAGACAGGGGTTTGGGGCTAAAAGCTATGAGCCGAGCCTCCGAGTCCAGTGGGAGTTAAT TCCCAGCTGACGGGGCCCTGCCTGATTTCTCAGGTACTAAGGTCTACATCGACCCCTTCACTTATGAAGA CCCTAATGAGGCTGTGAGGGAATTTGCAAAAGAGATCGATGTCTCCTACGTCAAGATTGAAGAGGTGATT GGTGCAGGTGAGAGCCGAAGGCTGCCCGGGCACCTGGGAACGAAGCGGGGGTGGGCAGGGCCACACTGGA GCGGGAGAGCTGATGACCTCTGCGTCCTTGTTTGAAGGTGAGTTTGGCGAGGTGTGCCGGGGGCGGCTCA AGGCCCCAGGGAAGAAGGAGAGCTGTGTGGCAATCAAGACCCTGAAGGGTGGCTACACGGAGCGGCAGCG GCGTGAGTTTCTGAGCGAGGCCTCCATCATGGGCCAGTTCGAGCACCCCAATATCATCCGCCTGGAGGGC GTGGTCACCAACAGCATGCCCGTCATGATTCTCACAGAGTTCATGGAGAACGGCGCCCTGGACTCCTTCC TGCGGGTGAGCACCCTCCCTGGCTTCTGCGGCCACCCGGAGTTCCCACTTACACCCAGAGGCCACTTGGG TTAAGAAGCCAGGACAGACAGTGGGTCCCAGGTCACCTCCTCCAGCCTTTTCCTCTTGGGCTAAGCCCTG GTCCTCTGCCTTTTCTTTTTTTTAAGACAGAGCCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGA TCTCGGCTCATTGCTGTCTCCACCTCCAGGGTTCAAGCGATTCTCCTGCCTCAGTCTCCCAAGTAGCTGG TACTATAGGCATGCACCACCATGCTGACTAATTTTTGTATTTTTAGTAGACACAGGGTTTCACCATGTAG GCCAGGCTGGTATCAAACTCCTGACCTCAAGTGATCTCCCCACCTCAGCCTCCCAAAGTGCTGGTATTAC AGGTGTGAGGCACCACGCCTGGCCAGCCCTCTGCCTTTAATTTTCCCTCTGGGAAAGGCTGGGCTCCTGG GACCTTCCTTTCCCACTGCCCCATACAGCTGAAGGTTGTCATTCCTTCTTTTTTTTTTTAATTTTGTTTT AATTGAATTTTTTTTTTTTGAGATGGAGTTTCACTCTTGTTGCCCAGGCCGGAGTGCAATGGCAAGATCT TGGCTCACCGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTTAGCCTCCCCAGTAGCTGGGAT TATAGGCATGTGCCACCACGCTTGACTAATTTTGTATTTTTAGTAGAGACGGGGGTTTCTCTGTGTTGGT CAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAG ACGTGAGCCACCGCGCCCGGCCAATTTTTTTTTTTTTTTTTTAAGACAGAGTCTCACTCTGTCCTCTAGG CTGGAGTGCAGTGGTGCATTCATAGCTCACTGTAGCCTTGACCTCCTGGGCTCAAGTGATCCTCCCGCCT CAGCCTCCTGAGTAGCTGGAACTACACTCATGTACCACCATGCTCAGCAAATTTTTAAAATTTTTTGTAG AGACAGGATCTCGATAGGTTGCCCAGGCTGGTCTGAACTCCTGGCCTCAAGCGAGCCTCCCTCCTCAGCC TCCCACAGCACTGGGATTGCAGGCATGAGCCACTGTGCCTGGCCTGTCATTCCTTCTTTTGACAAATATT TACTGAGTGCTTTCTACGCACCGGTCATCCTCCCAGTCCCCAGGAATAAAGCTATACACACGGCAAACTG GATTTCTCCTCTTGGGGAGCAGAGGGTCTAATGGGGCAGGGGGACTGAAAATTAGCAAGTAAATAGACAG GCTTTTTAAAAAAGTAAACAAATCATTTCAAATGTGAAAAAAAGCAAACGGGGTCCTTCATGCAGATGTG GCTAGAGAGGAAAGAGAACTGCTTAATTTATTTGGTCACTTTACCAGATTTTACTGACTTTTTTTTTTTT TTTAACTTTATTAAGCTTTTCTTTTTTCTTGAGATGGAGTTTCCATCTGTCACCCAGGCTGGAGTGCAGT GGTGCGTTCTTGGCTCACCGCAACGTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAG TAGCTTGGAATTGCATGGCATGCACCACCATACCCAGCTGATGTTTGTATTTTTAGTAGAGACAGGGTTT CATCATGTTGCCCAGGCTGGTCTTGAACTCCTGGGCTCAAGTGATCCACCCATCTCGGCCCCTCAAAGTG CTGGGATTACAGGCATGAGCCACCATGCCTGGCCTAGGCATCTTTTTAAAAAAATCAAAACATTTTTCTA TGTAGCAAAATAACATTGCATTGAACAGAGTTATAGCGATTCCCTAGCGTCATTGAATACCCAGTTGATT TTCACGTTTCTCTAGTTGTTCTAAAGATGTCCTTCACTGCTGCTTTATTCCAACCAGGATCCAGTTCAAG ACCGGGCTTTGTACCTGGTTATTATATATATTTTATTTATTTATTTTAGAAACAAGGTCTTGCCCTTTCG CCCAGTTTAGAGTGCAGTGGTGCAATCATAGCTCACTGCAGCCTCCAAACTCCTTGGCTCAGGTGATCCT CCTGCCTCAGCCTCCTGGGTAGCTGGAACTACAGGTGCACACCACCACACCTGGCTAATTTTTAAATTTT TTACGGAGATGGGGGTCTCGCTATGTTGCCCAGGCTGGTCTCAAACTCCTGGACTCAAGCGATCCTCCCT CCTTAACCTCTCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTGCTGATTATTATATTTTCGAGC CTCTCTAAATCTTGAGCAGTTCCTCATGATGACACTGACACACTGAAGGGTTAGGTCCCTTGTCCGCCTG AATGTCTTGATTTCTGGATTTATGAAATTCTTCTTATGGGATCATTTAGCTTGTCTCTCTGTATTTCCTG TAAGAGAAGCTCTATCTGATGTGGGGTTTTTTTGGTTTTGTTTGTTTGTTTTTTGAGATGGAGTCCTGCT GTCGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGAGAT TCTTCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGAGTGCCACCATGCCCAGCTAATTTTTGTAT TTTTAGTAGAGACAGGGTTTCACCATATTGGCCAGGATGGTCTCGAACTTCTGACCTCGTGATCTGCCCA CCACCTCAGCCTCCCACAGTGCTGGGATTACAGGCATGAGCCACTATGCCCGGCTAATTTTTGTATTTTT AGTAGAGACAGGGCTTCGCCATGTTGGCCAGGCTGATCTGAAACCCCTGGCCTCAAGCCATCCACCCTCC TTGGCCTCCCAAAGTGCTGGGATTAAACGCGTGAGCCACCGTGCCTGGTCGAAGAGACAGAAAGGGTCTT AAAGGTTCAGTGACACACACCTGTAATCCCAGCACTTTGGGAAGCTGAGGCTGGTGGATCACTCGAGGCC AGGAGTTAGAGATCACCCTGGGCAACATGGTGAAACCCCGTCTCTACACAAAATACAAAAATGGGCAGAG CATGATGGTGCATATCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCGGGAGGATCACTTAAGCCTGGGAG ATCGAGGCTGTAGTGAGCCATCATTGCACTACTGCATTCCAGCCTGGGCGATCCCATCTCTTAAAAAGAG AGAGAGATGGGAAGACCAGCACAGGTGAAACTGGTGAACAGAGGAGAGATGGTAGATGCTGCATTGGGCA GTGTGACGGGAACCCGCTGGAGGGCTTTGGCAGGAGAGTAGTTTAAGAGGATCCCAGCTGGGCACAGTGG CTCACACTTGTGATCCCAGCACTTGGGGAGGCCGGGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGAC CAGCCTGGCCAACATGGTGAAACCCTGTCTGTACTAAAAATACAAAAACCAGCCAGGCATGGTGGTGCAC CCCTGTAATCCCAGCTACTCAGGAGACTAAGACAGGAGAATCGCTTGAACTCAGGAGGCAGAGGTTGCAG TGAGCCAAGATCACGCCACTTTACTCCAGCCTGGGCAGTAGAGCGAGACTCCATCTCAAAAAAATAAATA AATAAAAAGACCTCTTTGCTGGGTGCTAGGGAGCAAGAGCAGGAGCTGGGAGAGGCCTGCAGCAGAAGCC TGTTGCCAGCATCCAGGCCGTGGGGTGAAGGGAAGGGTTTGGATTTGGGACATGTCTTGGAAGCATCACC AGCAGAACTTGCTGATGGATTGGAAGTGGCTGGTGAGGGAGAAAAGGGGGTCAAAGGAAACTCTGAGGTC TATACCCTGACCATCTGGCAAGTGGTGGTGTTGCCACAAACTGAGCGGGGAGTAGGGCAGGTGCAGGTCT GGAGGATGGATTCAAAATTCAGTTTTTGGAGTCTATGTCCCTGGTTCTGTAGGGCTGCAGATGGTCTGCC AAATCTTAGCGGAACCCAGAATACGGGATTTGTTTACTGTCTGTGACTTGTTGGTTTCCCTGGTGAGAGC AAACTCTTTAAAGGTCAAGGTTGGGCTTCAGACCTTGGTTTTTGCACCGATCATTGGTCATACTGCAGTT CCTCACTCTTCTCTTGCAAATCCATACACAGCTAGTCCAAGAGAGCTGAACAGCTTTGTGGTTGGATCAG CACCAATGTATCTCCACCTGTAGACGGGTTGCTCAGGTGACTCATGCCTGTAATCCCAGCACCTTGGGAG GCCAAGGTGGGAAGATTGCTTGAGGCCAGGAGTTGGAGACAAGCCTGGGAAACACAGTGAGACCCCATAT CTACCAAAAAAACCCCTTTGTTTTAATTAGCCAGGTGCAGTGGTGTGCACCTATAGTCCCAGCTACTAAG GAGGCTGAGGCAGAAGGATCATTTGAGCCCAGGAGTTTAAGGCTGCGGTGAACCATGATCGTGCCACTGC ACTCCAACCTGGGGGAAAGAAAGAGACCTTGTCTCTAAAAAAACTAAAAAACAGAAAAGCATTTGTTGAG TATTTCCTGGGTATAAAGCAGTGTACCAGGTTAAATGGAAGGAAAAGTTGAAATAATTTTTCAACTCATA ATCCGATTGGGAGAGACTGAATGCTTACCATTGAAGCAGGAACCATTGTAAGCAATGTGTTGTGATACTG TAGCAAGAGCTGAGAAAACTTGGGAAAAGAGAAAGGAGGAAGGCTCACCTGAGGGAGTTGGGGGGCTTGC CCTACAGGTGAGTTGTGAGGTGGGTCTGGAAGTGACAGATGCAGTTTAGGAAGTGGACGGGAGGCTGGGT ACGGTGACTCAACATCTGTAATCCCAGTGCTTTGGGAGACCCAGGCGGAAGGATCGCTTCAGGCCAGGAG TTAAAGACCAGCCTGGGCAACATAGTGGGAACCTATCTCTACTAAAAATTAAAAAATTATCCAGGCATAA TGGCACATGCCTATTGTTCCAGCTACTCAGGAGGCTTGCCTGAGCCCAGGAGGTTGAGGCTGCAGTGAGC TATGATGGCACCACTGCACTCCAGCCTGGGCGACAGAACAAGACCCTGTCTCTAAAAAAAAAAGATGTGG ATGGGAGGGGGAACGGTGGGTGGGCTGTCCTCACCAAGCCCCCACCCTATCTGCTCTCCAGCTAAACGAC GGACAGTTCACAGTCATCCAGCTCGTGGGCATGCTGCGGGGCATCGCCTCGGGCATGCGGTACCTTGCCG AGATGAGCTACGTCCACCGAGACCTGGCTGCTCGCAACATCCTAGTCAACAGCAACCTCGTCTGCAAAGT GTCTGACTTTGGCCTTTCCCGATTCCTGGAGGAGAACTCTTCCGATCCCACCTACACGAGCTCCCTGGTA ATGCTGGGGGTAATACTGGGTGTGAGCTTCTTAGGGCCAGGTGGGCAGGGCAGGTTGGAAAGGTGGGAGG CTGAGGGTTTGGCAGCCCTGCTCCAGGGAGAGGATACAGGAGCAGGCTGTGGGTGGGGGGACAGTCAGCT CCAGGAAGCCGACTTCCAGATGTCTAGGAAAATAACAGTTGGATAACCTGGGCAACATAGCAAGACCCCA TCTCTACAAAAAAATTAAAAGATTAGCCAGGCGCAGTGGCATGCACCTGTAGTCCCAGCTACTTGGGAGG TTGAGGCAGGAGGATTGCTTAAGCCCAGGAGTTGGAGGCTGCAGTGAGCTATGAATGTGCCACTGTACTG CAGACTGGGCGACAGAGCAAGACCCTGTCTCAAAAGAACAGTGGCCAGGTGTGGTGGCTCACGCCTGTAA ATCCAGCACTTTGGGAGGCTGAGGCAGGAGGATCGCCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAAC ATGGGAAAACCCTGTCGCTACTAAAAATACAAAATTAGCTGAGGGTGGTGGTACACGCCTGTAATCCGAG CTACTCAGGAGGCTGAGGTAGGAGAACCAGTTGAACCCGGGAGGCGGAGTTTCAGTGAGCCAAGATCGCA CCACTGCACTCCAACCTGGGCAAACAGAGTTGGAGAGTAGGAGGCTTGGGGCCTGAGCTAGGGGGAAAAA GCAGAGGCAGGTGGGGGACTGGGGGGCAGTGTGCTGGGTCTGGTGAGTCCCTCAGTGAGTCCCCCAGCTC ACCTTTTCTCCTTTTTCTGCAGGGAGGAAAGATTCCCATCCGATGGACTGCCCCGGAGGCCATTGCCTTC CGGAAGTTCACTTCCGCCAGTGATGCCTGGAGTTACGGGATTGTGATGTGGGAGGTGATGTCATTTGGGG AGAGGCCGTACTGGGACATGAGCAATCAGGACGTAAGTGTCCCGTGGTCCTACCAAGCTTTCCTCGAGTG TTCTCTCACCTGGGATTTGGGGTGAAGGGTGGGTTCCCAGAGAGTCATCACTGCTGGGTTCTTGAGACCA TGGAGATGACAAAAAGGAGAATTGATCTTTGTATCAAAGAGTTGAGATACAGGGCCAGGCCTAGTGGCTC AAGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCACCTAAGGTTAGGAGTTCAAGACCAG CCTGGCCAACATGGTGAAACCCCGTCTCTAAAAAAATACAAAAAATTAGCCCAGCATGATGGGCGGGTGC CTGTAATCCCAGCTACTCAGGAGGCTGAGACAGGATAATCGCTTGAACCCAGGAACAGAGGTTGCAGTGA GCTGAGATCACGCCATTGCTTTCCAGCCTGGGCAACTGAGCGAGACTCTGTCTTAATAAATAAATAAAAG AGTTGGGTACAGCATATTTGGGTCGCAGAAGGATGCAGAGATGGAGGGCAGGGTTGAGAGGTAACATGTC TGTATCATAGCCCAAGAGCTGCTGGGGCCTTCAGCCACAGAGAGCTTCAACTCCGGCTAGGAGGATTCCT GGATCTGTTATTTTTTGGGGGGCTGTGGCTCCTATCCTACCATCTTCCAAGTCACCATTTCCTGGGCCTG TTAGCATCTTTGCTTTTCCTGGACAGCCTCACCCAGAGCTTCTTCCCCTCTTTCCAGGTGATCAATGCCA TTGAACAGGACTACCGGCTGCCCCCGCCCCCAGACTGTCCCACCTCCCTCCACCAGCTCATGCTGGACTG TTGGCAGAAAGACCGGAATGCCCGGCCCCGCTTCCCCCAGGTGGTCAGCGCCCTGGACAAGATGATCCGG AACCCCGCCAGCCTCAAAATCGTGGCCCGGGAGAATGGCGGGTGAGGACTGCAGAGAATGGGCCCTCCTT CCCGCTCTCTGCCCCCACTCCTTGCCCAGAAGTGTCCGTTCATTGGTGTTGGGTGGGAGGGCCTCTGTCC GCCTCTGCAAGGCTGGGTTCCACCTCCTCCCCCGGACCTGGGCCTGGTACTCAGCATTCCTCCCCATCCT TGCCCCCTAGGGCCTCACACCCTCTCCTGGACCAGCGGCAGCCTCACTACTCAGCTTTTGGCTCTGTGGG CGAGTGGCTTCGGGCCATCAAAATGGGAAGATACGAAGAAAGTTTCGCAGCCGCTGGCTTTGGCTCCTTC GAGCTGGTCAGCCAGATCTCTGCTGAGTAAGCAGTGGCAGGAGCTGGAGTGGGGCTGGGAGAGCGGGGCA GCTGGAGTCAGGCCCACGGGGTCTCCAGGGGCTTTTGGGGTCAGCTTCGGGTGCCAATGCTGTCTTCTTG CACTGCGCTCATGCCATGCCTAGAAGGGCCCCAGAGGAGCAGTCACAGCCCCATGGAGCTGAGGACCCAA GGACTCTTTGGGGCCAGCCTGCCCGCCTCACCTCCTCCTGCCATCACAGCCCTGGGCCATCGCGCTTCCG CCTCTCACTTCTAGCTATCTTTGTGCATCTATCTGCATTCCAGGCCCGGCTCTCACGGTAACAATGTGTC AACTCGGGTTCTCTTTTTCCAACCATAAAAGGAGAAGATTGGGCTAGGTTTTGGAGATCCTCTTCAGCTT TTATGTGAAATGGTTTTATGATTCCTTGCCTCCCAAAGGCTGCGTATCCCCACTTGGCCTTTGTCTGCTA CTCCCCCTTTCTGCCTTCCCGTTCCTCTCCCAAGATCTCCTCTCACCCCAGGTTGAATAACAGAAATAGA AGGAATAGAAATCTGAAGGCCGGGCATGGTGGCTCATGCCTGTAATGCCAGCACTTTGGGAGGCCGAGGT GGGCAGATCACTTGAGGTTAGGAGTTCGAGACCATTGTGGACAACTTGGTGAAACCTTATGTCTACTAAA AATACAAAAATTAGCTGGGCATGGTGGTGCGTGCCTGTAATACCAGCTACTGAGGAGGCTGAGGCAGGAG AATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGATGA CAGAGTGAAATTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAGAAATGTGAAGGCCAGGTGGTGGCTCA CGCCTGTAATCTCAGCACTTTGGGAGGCTCAGGTGGACCGATTGCTTGAGCCCAGGAGTTTGAGAGCAGC CTGGCCAAAATAGCAAAACCCCATCTCTACAAAACAAAAACAAAAAAATTAGCTGGGCATGGTGGTGCGT GCCTGTGGTCCCAGCTACTCAGGAGGCTAGAGCCAGAGGGTCTCAGGCCAGTCTGCCCCTGCCCCACGGG GCCTGGGCACATCCCTCCCTAATTCTTCCCAGCCTCTCTCTGACCCAGGGGGCCTCCTCTCCCTTTTTTC CCCTTATCTCAGCCTCCAGCCATCAGCAACCTCCTCTTCCTCTCCACCCAGCTCTTCCTCTCCCACTTCG GCCTTTTCTTTCTCACACTCCATTTCCCTCTACGGCAATCTGTGCAGCCTCTTCCCCCAGTCTCATTTTG CGGGCTTTTCTCTCTTTTCTTTCCTTCCCTGGCACCCAAGCCAAAGGCCCTGCCTCTGGCCTCCAGCCCT ACCCCCTTCTGCGGTTGCACAGAAGGATGGCTGCCCAGCTCTTAAAAAAACTGCCCGGGAACTGTTGACA TCTGTTCTCCCTCCCCCGCTGGCTTTTCTGATTGGCTTACAATCCTGAGGCTAGGACCGTCTCAGGAGCC AAGAGAGGAGAGCGGCCACAGGGAACCTAGGGTCTCACCAAGCTCTCCTTTCCTTCTGCAGGGACCTGCT CCGAATCGGAGTCACTCTGGCGGGACACCAGAAGAAAATCTTGGCCAGTGTCCAGCACATGAAGTCCCAG GCCAAGCCGGGAACCCCGGGTGGGACAGGAGGACCGGCCCCGCAGTACTGACCTGCAGGAACTCCCCACC CCAGGGACACCGCCTCCCCATTTTCCGGGGCAGAGTGGGGACTCACAGAGGCCCCCAGCCCTGTGCCCCG CTGGATTGCACTTTGAGCCCGTGGGGTGAGGAGTTGGCAATTTGGAGAGACAGGATTTGGGGGTTCTGCC ATAATAGGAGGGGAAAATCACCCCCCAGCCACCTCGGGGAACTCCAGACCAAGGGTGAGGGCGCCTTTCC CTCAGGACTGGGTGTGACCAGAGGAAAAGGAAGTGCCCAACATCTCCCAGCCTCCCCAGGTGCCCCCCTC ACCTTGATGGGTGCGTTCCCGCAGACCAAAGAGAGTGTGACTCCCTTGCCAGCTCCAGAGTGGGGGGGCT GTCCCAGGGGGCAAGAAGGGGTGTCAGGGCCCAGTGACAAAATCATTGGGGTTTGTAGTCCCAACTTGCT GCTGTCACCACCAAACTCAATCATTTTTTTCCCTTGTAAATGCCCCTCCCCCAGCTGCTGCCTTCATATT GAAGGTTTTTGAGTTTTGTTTTTGGTCTTAATTTTTCTCCCCGTTCCCTTTTTGTTTCTTCGTTTTGTTT TTCTACCGTCCTTGTCATAACTTTGTGTTGGAGGGAACCTGTTTCACTATGGCCTCCTTTGCCCAAGTTG AAACAGGGGCCCATCATCATGTCTGTTTCCAGAACAGTGCCTTGGTCATCCCACATCCCCGGACCCCGCC TGGGACCCCCAAGCTGTGTCCTATGAAGGGGTGTGGGGTGAGGTAGTGAAAAGGGCGGTAGTTGGTGGTG GAACCCAGAAACGGACGCCGGTGCTTGGAGGGGTTCTTAAATTATATTTAAAAAAGTAACTTTTTGTATA AATAAAAGAAAATGGGACGTGTCCCAGCTCCAGGGGT Download Select all
Length	24957
OMIM ID	600011
HGNC ID	HGNC:3395
Unigene ID	Hs.437008
Ensembl ID	ENSG00000196411
PharmGKB ID	-

mRNA Information

mRNA ID	NM_004444.4
Exon	join(1..543,3249..3319,3591..3878,4855..5251,7226..7381, 7633..7965,8878..9002,10165..10330,13501..13603, 13806..13870,14314..14427,14528..14775,19942..20157, 20953..21102,21828..22021,22201..22356,23932..24957)
mRNA Sequence	>2050 TTCCAGCGCAGCTCAGCCCCTGCCCGGCCCGGCCCGCCCGGCTCCGCGCCGCAGTCTCCCTCCC TCCCGCTCCGTCCCCGCTCGGGCTCCCACCATCCCCGCCCGCGAGGAGAGCACTCGGCCCGGCG GCGCGAGCAGAGCCACTCCAGGGAGGGGGGGAGACCGCGAGCGGCCGGCTCAGCCCCCGCCACC CGGGGCGGGACCCCGAGGCCCCGGAGGGACCCCAACTCCAGCCACGTCTTGCTGCGCGCCCGCC CGGCGCGGCCACTGCCAGCACGCTCCGGGCCCGCCGCCCGCGCGCGCGGCACAGACGCGGGGCC ACACTTGGCGCCGCCGCCCGGTGCCCCGCACGCTCGCATGGGCCCGCGCTGAGGGCCCCGACGA GGAGTCCCGCGCGGAGTATCGGCGTCCACCCGCCCAGGGAGAGTCAGACCTGGGGGGGCGAGGG CCCCCCAAACTCAGTTCGGATCCTACCCGAGTGAGGCGGCGCCATGGAGCTCCGGGTGCTGCTC TGCTGGGCTTCGTTGGCCGCAGCTTTGGAAGAGACCCTGCTGAACACAAAATTGGAAACTGCTG ATCTGAAGTGGGTGACATTCCCTCAGGTGGACGGGCAGTGGGAGGAACTGAGCGGCCTGGATGA GGAACAGCACAGCGTGCGCACCTACGAAGTGTGTGACGTGCAGCGTGCCCCGGGCCAGGCCCAC TGGCTTCGCACAGGTTGGGTCCCACGGCGGGGCGCCGTCCACGTGTACGCCACGCTGCGCTTCA CCATGCTCGAGTGCCTGTCCCTGCCTCGGGCTGGGCGCTCCTGCAAGGAGACCTTCACCGTCTT CTACTATGAGAGCGATGCGGACACGGCCACGGCCCTCACGCCAGCCTGGATGGAGAACCCCTAC ATCAAGGTGGACACGGTGGCCGCGGAGCATCTCACCCGGAAGCGCCCTGGGGCCGAGGCCACCG GGAAGGTGAATGTCAAGACGCTGCGTCTGGGACCGCTCAGCAAGGCTGGCTTCTACCTGGCCTT CCAGGACCAGGGTGCCTGCATGGCCCTGCTATCCCTGCACCTCTTCTACAAAAAGTGCGCCCAG CTGACTGTGAACCTGACTCGATTCCCGGAGACTGTGCCTCGGGAGCTGGTTGTGCCCGTGGCCG GTAGCTGCGTGGTGGATGCCGTCCCCGCCCCTGGCCCCAGCCCCAGCCTCTACTGCCGTGAGGA TGGCCAGTGGGCCGAACAGCCGGTCACGGGCTGCAGCTGTGCTCCGGGGTTCGAGGCAGCTGAG GGGAACACCAAGTGCCGAGCCTGTGCCCAGGGCACCTTCAAGCCCCTGTCAGGAGAAGGGTCCT GCCAGCCATGCCCAGCCAATAGCCACTCTAACACCATTGGATCAGCCGTCTGCCAGTGCCGCGT CGGGTACTTCCGGGCACGCACAGACCCCCGGGGTGCACCCTGCACCACCCCTCCTTCGGCTCCG CGGAGCGTGGTTTCCCGCCTGAACGGCTCCTCCCTGCACCTGGAATGGAGTGCCCCCCTGGAGT CTGGTGGCCGAGAGGACCTCACCTACGCCCTCCGCTGCCGGGAGTGCCGACCCGGAGGCTCCTG TGCGCCCTGCGGGGGAGACCTGACTTTTGACCCCGGCCCCCGGGACCTGGTGGAGCCCTGGGTG GTGGTTCGAGGGCTACGTCCTGACTTCACCTATACCTTTGAGGTCACTGCATTGAACGGGGTAT CCTCCTTAGCCACGGGGCCCGTCCCATTTGAGCCTGTCAATGTCACCACTGACCGAGAGGTACC TCCTGCAGTGTCTGACATCCGGGTGACGCGGTCCTCACCCAGCAGCTTGAGCCTGGCCTGGGCT GTTCCCCGGGCACCCAGTGGGGCTGTGCTGGACTACGAGGTCAAATACCATGAGAAGGGCGCCG AGGGTCCCAGCAGCGTGCGGTTCCTGAAGACGTCAGAAAACCGGGCAGAGCTGCGGGGGCTGAA GCGGGGAGCCAGCTACCTGGTGCAGGTACGGGCGCGCTCTGAGGCCGGCTACGGGCCCTTCGGC CAGGAACATCACAGCCAGACCCAACTGGATGAGAGCGAGGGCTGGCGGGAGCAGCTGGCCCTGA TTGCGGGCACGGCAGTCGTGGGTGTGGTCCTGGTCCTGGTGGTCATTGTGGTCGCAGTTCTCTG CCTCAGGAAGCAGAGCAATGGGAGAGAAGCAGAATATTCGGACAAACACGGACAGTATCTCATC GGACATGGTACTAAGGTCTACATCGACCCCTTCACTTATGAAGACCCTAATGAGGCTGTGAGGG AATTTGCAAAAGAGATCGATGTCTCCTACGTCAAGATTGAAGAGGTGATTGGTGCAGGTGAGTT TGGCGAGGTGTGCCGGGGGCGGCTCAAGGCCCCAGGGAAGAAGGAGAGCTGTGTGGCAATCAAG ACCCTGAAGGGTGGCTACACGGAGCGGCAGCGGCGTGAGTTTCTGAGCGAGGCCTCCATCATGG GCCAGTTCGAGCACCCCAATATCATCCGCCTGGAGGGCGTGGTCACCAACAGCATGCCCGTCAT GATTCTCACAGAGTTCATGGAGAACGGCGCCCTGGACTCCTTCCTGCGGCTAAACGACGGACAG TTCACAGTCATCCAGCTCGTGGGCATGCTGCGGGGCATCGCCTCGGGCATGCGGTACCTTGCCG AGATGAGCTACGTCCACCGAGACCTGGCTGCTCGCAACATCCTAGTCAACAGCAACCTCGTCTG CAAAGTGTCTGACTTTGGCCTTTCCCGATTCCTGGAGGAGAACTCTTCCGATCCCACCTACACG AGCTCCCTGGGAGGAAAGATTCCCATCCGATGGACTGCCCCGGAGGCCATTGCCTTCCGGAAGT TCACTTCCGCCAGTGATGCCTGGAGTTACGGGATTGTGATGTGGGAGGTGATGTCATTTGGGGA GAGGCCGTACTGGGACATGAGCAATCAGGACGTGATCAATGCCATTGAACAGGACTACCGGCTG CCCCCGCCCCCAGACTGTCCCACCTCCCTCCACCAGCTCATGCTGGACTGTTGGCAGAAAGACC GGAATGCCCGGCCCCGCTTCCCCCAGGTGGTCAGCGCCCTGGACAAGATGATCCGGAACCCCGC CAGCCTCAAAATCGTGGCCCGGGAGAATGGCGGGGCCTCACACCCTCTCCTGGACCAGCGGCAG CCTCACTACTCAGCTTTTGGCTCTGTGGGCGAGTGGCTTCGGGCCATCAAAATGGGAAGATACG AAGAAAGTTTCGCAGCCGCTGGCTTTGGCTCCTTCGAGCTGGTCAGCCAGATCTCTGCTGAGGA CCTGCTCCGAATCGGAGTCACTCTGGCGGGACACCAGAAGAAAATCTTGGCCAGTGTCCAGCAC ATGAAGTCCCAGGCCAAGCCGGGAACCCCGGGTGGGACAGGAGGACCGGCCCCGCAGTACTGAC CTGCAGGAACTCCCCACCCCAGGGACACCGCCTCCCCATTTTCCGGGGCAGAGTGGGGACTCAC AGAGGCCCCCAGCCCTGTGCCCCGCTGGATTGCACTTTGAGCCCGTGGGGTGAGGAGTTGGCAA TTTGGAGAGACAGGATTTGGGGGTTCTGCCATAATAGGAGGGGAAAATCACCCCCCAGCCACCT CGGGGAACTCCAGACCAAGGGTGAGGGCGCCTTTCCCTCAGGACTGGGTGTGACCAGAGGAAAA GGAAGTGCCCAACATCTCCCAGCCTCCCCAGGTGCCCCCCTCACCTTGATGGGTGCGTTCCCGC AGACCAAAGAGAGTGTGACTCCCTTGCCAGCTCCAGAGTGGGGGGGCTGTCCCAGGGGGCAAGA AGGGGTGTCAGGGCCCAGTGACAAAATCATTGGGGTTTGTAGTCCCAACTTGCTGCTGTCACCA CCAAACTCAATCATTTTTTTCCCTTGTAAATGCCCCTCCCCCAGCTGCTGCCTTCATATTGAAG GTTTTTGAGTTTTGTTTTTGGTCTTAATTTTTCTCCCCGTTCCCTTTTTGTTTCTTCGTTTTGT TTTTCTACCGTCCTTGTCATAACTTTGTGTTGGAGGGAACCTGTTTCACTATGGCCTCCTTTGC CCAAGTTGAAACAGGGGCCCATCATCATGTCTGTTTCCAGAACAGTGCCTTGGTCATCCCACAT CCCCGGACCCCGCCTGGGACCCCCAAGCTGTGTCCTATGAAGGGGTGTGGGGTGAGGTAGTGAA AAGGGCGGTAGTTGGTGGTGGAACCCAGAAACGGACGCCGGTGCTTGGAGGGGTTCTTAAATTA TATTTAAAAAAGTAACTTTTTGTATAAATAAAAGAAAATGGGACGTGTCCCAGCTCCAGGGGTA AAAAAAAAAAAAAAAAA Download Select all
Length	4369

CDS Information

Location	join(492..543,3249..3319,3591..3878,4855..5251,7226..7381, 7633..7965,8878..9002,10165..10330,13501..13603, 13806..13870,14314..14427,14528..14775,19942..20157, 20953..21102,21828..22021,22201..22356,23932..24061)
CDS Sequence	>gi\|55774978:492-3455 Homo sapiens EPH receptor B4 (EPHB4), mRNA ATGGAGCTCCGGGTGCTGCTCTGCTGGGCTTCGTTGGCCGCAGCTTTGGAAGAGACCCTGCTGAACACAA AATTGGAAACTGCTGATCTGAAGTGGGTGACATTCCCTCAGGTGGACGGGCAGTGGGAGGAACTGAGCGG CCTGGATGAGGAACAGCACAGCGTGCGCACCTACGAAGTGTGTGACGTGCAGCGTGCCCCGGGCCAGGCC CACTGGCTTCGCACAGGTTGGGTCCCACGGCGGGGCGCCGTCCACGTGTACGCCACGCTGCGCTTCACCA TGCTCGAGTGCCTGTCCCTGCCTCGGGCTGGGCGCTCCTGCAAGGAGACCTTCACCGTCTTCTACTATGA GAGCGATGCGGACACGGCCACGGCCCTCACGCCAGCCTGGATGGAGAACCCCTACATCAAGGTGGACACG GTGGCCGCGGAGCATCTCACCCGGAAGCGCCCTGGGGCCGAGGCCACCGGGAAGGTGAATGTCAAGACGC TGCGTCTGGGACCGCTCAGCAAGGCTGGCTTCTACCTGGCCTTCCAGGACCAGGGTGCCTGCATGGCCCT GCTATCCCTGCACCTCTTCTACAAAAAGTGCGCCCAGCTGACTGTGAACCTGACTCGATTCCCGGAGACT GTGCCTCGGGAGCTGGTTGTGCCCGTGGCCGGTAGCTGCGTGGTGGATGCCGTCCCCGCCCCTGGCCCCA GCCCCAGCCTCTACTGCCGTGAGGATGGCCAGTGGGCCGAACAGCCGGTCACGGGCTGCAGCTGTGCTCC GGGGTTCGAGGCAGCTGAGGGGAACACCAAGTGCCGAGCCTGTGCCCAGGGCACCTTCAAGCCCCTGTCA GGAGAAGGGTCCTGCCAGCCATGCCCAGCCAATAGCCACTCTAACACCATTGGATCAGCCGTCTGCCAGT GCCGCGTCGGGTACTTCCGGGCACGCACAGACCCCCGGGGTGCACCCTGCACCACCCCTCCTTCGGCTCC GCGGAGCGTGGTTTCCCGCCTGAACGGCTCCTCCCTGCACCTGGAATGGAGTGCCCCCCTGGAGTCTGGT GGCCGAGAGGACCTCACCTACGCCCTCCGCTGCCGGGAGTGCCGACCCGGAGGCTCCTGTGCGCCCTGCG GGGGAGACCTGACTTTTGACCCCGGCCCCCGGGACCTGGTGGAGCCCTGGGTGGTGGTTCGAGGGCTACG TCCTGACTTCACCTATACCTTTGAGGTCACTGCATTGAACGGGGTATCCTCCTTAGCCACGGGGCCCGTC CCATTTGAGCCTGTCAATGTCACCACTGACCGAGAGGTACCTCCTGCAGTGTCTGACATCCGGGTGACGC GGTCCTCACCCAGCAGCTTGAGCCTGGCCTGGGCTGTTCCCCGGGCACCCAGTGGGGCTGTGCTGGACTA CGAGGTCAAATACCATGAGAAGGGCGCCGAGGGTCCCAGCAGCGTGCGGTTCCTGAAGACGTCAGAAAAC CGGGCAGAGCTGCGGGGGCTGAAGCGGGGAGCCAGCTACCTGGTGCAGGTACGGGCGCGCTCTGAGGCCG GCTACGGGCCCTTCGGCCAGGAACATCACAGCCAGACCCAACTGGATGAGAGCGAGGGCTGGCGGGAGCA GCTGGCCCTGATTGCGGGCACGGCAGTCGTGGGTGTGGTCCTGGTCCTGGTGGTCATTGTGGTCGCAGTT CTCTGCCTCAGGAAGCAGAGCAATGGGAGAGAAGCAGAATATTCGGACAAACACGGACAGTATCTCATCG GACATGGTACTAAGGTCTACATCGACCCCTTCACTTATGAAGACCCTAATGAGGCTGTGAGGGAATTTGC AAAAGAGATCGATGTCTCCTACGTCAAGATTGAAGAGGTGATTGGTGCAGGTGAGTTTGGCGAGGTGTGC CGGGGGCGGCTCAAGGCCCCAGGGAAGAAGGAGAGCTGTGTGGCAATCAAGACCCTGAAGGGTGGCTACA CGGAGCGGCAGCGGCGTGAGTTTCTGAGCGAGGCCTCCATCATGGGCCAGTTCGAGCACCCCAATATCAT CCGCCTGGAGGGCGTGGTCACCAACAGCATGCCCGTCATGATTCTCACAGAGTTCATGGAGAACGGCGCC CTGGACTCCTTCCTGCGGCTAAACGACGGACAGTTCACAGTCATCCAGCTCGTGGGCATGCTGCGGGGCA TCGCCTCGGGCATGCGGTACCTTGCCGAGATGAGCTACGTCCACCGAGACCTGGCTGCTCGCAACATCCT AGTCAACAGCAACCTCGTCTGCAAAGTGTCTGACTTTGGCCTTTCCCGATTCCTGGAGGAGAACTCTTCC GATCCCACCTACACGAGCTCCCTGGGAGGAAAGATTCCCATCCGATGGACTGCCCCGGAGGCCATTGCCT TCCGGAAGTTCACTTCCGCCAGTGATGCCTGGAGTTACGGGATTGTGATGTGGGAGGTGATGTCATTTGG GGAGAGGCCGTACTGGGACATGAGCAATCAGGACGTGATCAATGCCATTGAACAGGACTACCGGCTGCCC CCGCCCCCAGACTGTCCCACCTCCCTCCACCAGCTCATGCTGGACTGTTGGCAGAAAGACCGGAATGCCC GGCCCCGCTTCCCCCAGGTGGTCAGCGCCCTGGACAAGATGATCCGGAACCCCGCCAGCCTCAAAATCGT GGCCCGGGAGAATGGCGGGGCCTCACACCCTCTCCTGGACCAGCGGCAGCCTCACTACTCAGCTTTTGGC TCTGTGGGCGAGTGGCTTCGGGCCATCAAAATGGGAAGATACGAAGAAAGTTTCGCAGCCGCTGGCTTTG GCTCCTTCGAGCTGGTCAGCCAGATCTCTGCTGAGGACCTGCTCCGAATCGGAGTCACTCTGGCGGGACA CCAGAAGAAAATCTTGGCCAGTGTCCAGCACATGAAGTCCCAGGCCAAGCCGGGAACCCCGGGTGGGACA GGAGGACCGGCCCCGCAGTACTGA Download Select all
CCDS ID	CCDS5706.1

Protein Information

Protein ID	NP_004435.3
Protein Name	EPH receptor B4
Molecular Wt. (Da)	106642
Protein Sequence	>2050 MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQ RAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTP AWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHL FYKKCAQLTVNLTRFPETVPRELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCSCA PGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTDPRGAPC TTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGSCAPCGGDLTFDPGPR DLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPS SLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSE AGYGPFGQEHHSQTQLDESEGWREQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSD KHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKK ESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSF LRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEEN SSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINA IEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASH PLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKK ILASVQHMKSQAKPGTPGGTGGPAPQY Download Select all
Length	987
Uniprot ID	Q02223
Ensembl Protein ID	ENSP00000053243

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	976
S	Phosphorylation	769
Y	Phosphorylation	774
T	Phosphorylation	953
S	Phosphorylation	911
Y	Phosphorylation	590
Y	Phosphorylation	596
Y	Phosphorylation	574
Y	Phosphorylation	906
T	Phosphorylation	595

Enzyme Information

EC	2.7.10.2
Name	non-specific protein-tyrosine kinase ABL ABL1 ABL2 ABLL ACK1 ACK2 AGMX1 ARG ATK ATP:protein-tyrosine O-phosphotransferase (ambiguous) BLK Bmk BMX BRK Bruton's tyrosine kinase Bsk BTK BTKL CAKb Cdgip CHK CSK CTK CYL cytoplasmic protein tyrosine kinase EMT ETK Fadk FAK FAK2 FER Fert1/2 FES FGR focal adhesion kinase FPS FRK FYN HCK HCTK HYL IMD1 ITK IYK JAK1 JAK2 JAK3 Janus kinase 1 Janus kinase 2 Janus kinase 3 JTK1 JTK9 L-JAK LCK LSK LYN MATK Ntk p60c-src protein tyrosine kinase PKB protein-tyrosine kinase (ambiguous) PSCTK PSCTK1 PSCTK2 PSCTK4 PSCTK5 PTK2 PTK2B PTK6 PYK2 RAFTK RAK Rlk Sik SLK SRC SRC2 SRK SRM SRMS STD SYK SYN Tck TEC TNK1 Tsk TXK TYK2 TYK3 YES1 YK2 ZAP70
Class	Transferases; Transferring phosphorus-containing groups; Protein-tyrosine kinases
Sysname	ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)
Substrate	ATP [CPD:C00002]; [protein]-L-tyrosine
Product	ADP [CPD:C00008]; [protein]-L-tyrosine phosphate
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
9672	SDC3	1719	NP_055469.3	in vitro	9388509

Pathway Information

Pathway Name	Pathway ID
Axon guidance	hsa04360

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd05065	610-878	PTKc_EphR_B
cl21453	610-878	PKc_like superfamily
cd10474	17-196	EphR_LBD_B4
cl02704	17-196	EphR_LBD superfamily
cd09554	907-973	SAM_EPH-B4
cl15755	907-973	SAM_superfamily superfamily
cd00063	434-526	FN3
cl21522	434-526	FN3 superfamily
cd00063	324-429	FN3
cl21522	324-429	FN3 superfamily
cd05033	610-878	PTKc_EphR
cd05066	610-878	PTKc_EphR_A
cd05063	609-878	PTKc_EphR_A2
cd05064	609-878	PTKc_EphR_A10
cd00192	619-875	PTKc
cd05034	621-875	PTKc_Src_like
pfam01404	17-197	Ephrin_lbd
cd05068	609-867	PTKc_Frk_like
cd10319	18-196	EphR_LBD
smart00615	17-196	EPH_lbd
cd05041	619-875	PTKc_Fes_like
cd05060	621-874	PTKc_Syk_like
cd05039	615-874	PTKc_Csk_like
cd05056	609-874	PTKc_FAK
cd05059	610-874	PTKc_Tec_like
cd13999	621-874	STKc_MAP3K-like
cd05148	617-875	PTKc_Srm_Brk
cd05032	609-875	PTKc_InsR_like
cd05048	609-870	PTKc_Ror
cd05067	609-875	PTKc_Lck_Blk
cd14203	621-875	PTKc_Src_Fyn_like
cd05044	621-874	PTKc_c-ros
cd05052	609-878	PTKc_Abl
cd05072	607-875	PTKc_Lyn
cd05040	619-874	PTKc_Ack_like
cd05057	620-881	PTKc_EGFR_like
cd05049	619-876	PTKc_Trk
cd05112	610-874	PTKc_Itk
cd05051	616-870	PTKc_DDR
cd05084	619-874	PTKc_Fes
cd10472	18-196	EphR_LBD_B
cd10478	17-196	EphR_LBD_B3
cd05073	607-875	PTKc_Hck
cd05115	617-870	PTKc_Zap-70
cd05085	619-870	PTKc_Fer
cd05071	607-867	PTKc_Src
cd05069	607-875	PTKc_Yes
cd05050	609-876	PTKc_Musk
cd05070	609-875	PTKc_Fyn
cd05113	621-874	PTKc_Btk_Bmx
cd05090	609-870	PTKc_Ror1
cd05114	610-878	PTKc_Tec_Rlk
cd05053	609-878	PTKc_FGFR
cd05036	608-876	PTKc_ALK_LTK
cd05091	608-874	PTKc_Ror2
cd05083	610-877	PTKc_Chk
cd05109	608-887	PTKc_HER2
cd05038	621-875	PTKc_Jak_rpt2
cd05045	617-880	PTKc_RET
cd05058	619-872	PTKc_Met_Ron
cd05035	615-878	PTKc_TAM
cd05092	621-874	PTKc_TrkA
cd05108	616-882	PTKc_EGFR
cd05097	615-874	PTKc_DDR_like
cd05082	615-875	PTKc_Csk
cd05046	620-876	PTK_CCK4
cd05116	621-870	PTKc_Syk
cd05075	615-880	PTKc_Axl
cd14204	610-878	PTKc_Mer
cd05095	618-874	PTKc_DDR2
cd05061	621-874	PTKc_InsR
cd05110	608-881	PTKc_HER4
cd10476	18-196	EphR_LBD_B1
cd05096	613-874	PTKc_DDR1
cd05074	620-875	PTKc_Tyro3
cd10477	16-196	EphR_LBD_B2
cd05047	619-877	PTKc_Tie
cd05099	621-878	PTKc_FGFR4
cd05089	615-878	PTKc_Tie1
cd10473	17-196	EphR_LBD_A
cd05101	596-878	PTKc_FGFR2
cd05093	621-879	PTKc_TrkB
cd05054	605-874	PTKc_VEGFR
cd05055	589-878	PTKc_PDGFR
cd10475	17-196	EphR_LBD_B6
cd05111	619-881	PTK_HER3
cd05062	621-874	PTKc_IGF-1R
cd05094	621-877	PTKc_TrkC
cd10485	15-197	EphR_LBD_A7
cd05043	615-874	PTK_Ryk
cd05098	621-878	PTKc_FGFR1
cd05088	610-878	PTKc_Tie2
cd10487	20-196	EphR_LBD_A10
cd10482	17-196	EphR_LBD_A4
cd05100	609-878	PTKc_FGFR3
cd14205	614-877	PTKc_Jak2_rpt2
cd00180	621-872	PKc
cd14207	605-874	PTKc_VEGFR1
cd10486	17-196	EphR_LBD_A8
cd10481	17-196	EphR_LBD_A3
cd05103	615-879	PTKc_VEGFR2
cd05079	621-878	PTKc_Jak1_rpt2
cd10483	17-196	EphR_LBD_A5
cd05102	609-879	PTKc_VEGFR3
cd10484	20-196	EphR_LBD_A6
cd14059	621-875	STKc_MAP3K12_13
cd14014	616-866	STKc_PknB_like
cd14061	620-877	STKc_MLK
cd14058	621-874	STKc_TAK1
cd13978	621-867	STKc_RIP
cd10480	17-197	EphR_LBD_A2
cd05106	594-879	PTKc_CSF-1R
cd14062	621-875	STKc_Raf
cd06606	619-865	STKc_MAPKKK
cd05081	614-877	PTKc_Jak3_rpt2
cd05080	614-877	PTKc_Tyk2_rpt2
cd05107	594-878	PTKc_PDGFR_beta
cd14150	615-879	STKc_A-Raf
cd14066	621-877	STKc_IRAK
cd14060	622-877	STKc_MLTK
cd05105	589-867	PTKc_PDGFR_alpha
cd14149	609-875	STKc_C-Raf
cd05104	589-878	PTKc_Kit
cd06627	619-865	STKc_Cdc7_like
cd14151	609-880	STKc_B-Raf
cd05122	614-865	PKc_STE
cd14145	609-874	STKc_MLK1
cd14146	620-874	STKc_MLK4
cd14148	620-875	STKc_MLK2
cd14003	616-870	STKc_AMPK-like
cd14154	621-877	STKc_LIMK
cd14147	611-877	STKc_MLK3
cd14206	621-857	PTKc_Aatyk3
cd10479	17-196	EphR_LBD_A1
cd05042	621-857	PTKc_Aatyk
cd09488	908-968	SAM_EPH-R
cd14221	621-880	STKc_LIMK1
cd14222	621-877	STKc_LIMK2
cd05037	617-874	PTK_Jak_rpt1
cd08215	616-865	STKc_Nek
cd05086	617-842	PTKc_Aatyk2
cd05087	621-870	PTKc_Aatyk1
cd14065	621-874	PKc_LIMK_like
cd05117	616-843	STKc_CAMK
cd14064	621-875	PKc_TNNI3K
cd13992	644-877	PK_GC
cd09552	904-971	SAM_EPH-B2
cd09553	904-971	SAM_EPH-B3
cd13998	619-864	STKc_TGFbR-like
cd14009	621-853	STKc_ATG1_ULK_like
cd06614	619-865	STKc_PAK
cd06623	613-865	PKc_MAPKK_plant_like
cd14008	621-864	STKc_LKB1_CaMKK
cd06628	620-865	STKc_Byr2_like
cd14025	619-882	STKc_RIP4_like
cd09551	904-971	SAM_EPH-B1
cd07840	614-812	STKc_CDK9_like
cd14155	621-879	PKc_TESK
cd14664	621-881	STK_BAK1_like
cd14054	619-864	STKc_BMPR2_AMHR2
cd14002	619-870	STKc_STK36
cd06648	613-883	STKc_PAK_II
cd14056	619-877	STKc_TGFbR_I
cd06632	619-865	STKc_MEKK1_plant
cd14063	615-879	PK_KSR
cd14027	623-870	STKc_RIP1
cd13979	615-821	STKc_Mos
cd14158	621-877	STKc_IRAK4
cd14073	617-854	STKc_NUAK
cd06612	617-865	STKc_MST1_2
cd07829	614-814	STKc_CDK_like
cd06659	613-901	STKc_PAK6
cd07830	616-865	STKc_MAK_like
cd09546	908-971	SAM_EPH-A5
cd14026	621-879	STKc_RIP2
cd14007	621-872	STKc_Aurora
cd14121	619-867	STKc_ULK3
cd14202	618-867	STKc_ULK1
cd14201	611-867	STKc_ULK2
cd06620	621-879	PKc_Byr1_like
cd06629	612-865	STKc_Bck1_like
cd14080	617-872	STKc_TSSK-like
cd14103	621-829	STKc_MLCK
cd06640	614-865	STKc_MST4
cd06611	621-879	STKc_SLK_like
cd06609	616-865	STKc_MST3_like
cd14120	621-866	STKc_ULK1_2-like
cd05078	618-875	PTK_Jak2_rpt1
cd08222	617-865	STKc_Nek11
cd14099	616-872	STKc_PLK
cd07834	616-822	STKc_MAPK
cd14000	620-874	STKc_LRRK
cd13996	616-812	STKc_EIF2AK
cd13997	618-871	PKc_Wee1_like
cd14042	644-877	PK_GC-A_B
cd07866	616-820	STKc_BUR1
cd14084	608-830	STKc_Chk2
cd09548	904-971	SAM_EPH-A7
cd14081	616-855	STKc_BRSK1_2
pfam00536	905-969	SAM_1
cd14055	619-864	STKc_TGFbR2_like
cd08529	617-865	STKc_FA2-like
cd14038	621-821	STKc_IKK_beta
cd14190	618-833	STKc_MLCK2
cd13989	621-821	STKc_IKK
cd14167	619-864	STKc_CaMKI_alpha
cd14053	619-815	STKc_ACVR2
cd05123	621-864	STKc_AGC
cd14161	619-854	STKc_NUAK2
cd08217	619-866	STKc_Nek2
cd06605	620-869	PKc_MAPKK
cd07843	616-815	STKc_CDC2L1
cd08224	616-865	STKc_Nek6_7
cd14052	618-813	PTKc_Wee1_fungi
cd09545	907-971	SAM_EPH-A4
cd05118	620-835	STKc_CMGC
cd05580	615-823	STKc_PKA_like
cd06610	616-865	STKc_OSR1_SPAK
cd14057	627-877	PK_ILK
cd14663	620-870	STKc_SnRK3
cd06631	619-865	STKc_YSK4
cd07833	619-870	STKc_CDKL
cd09550	911-971	SAM_EPH-A8
cd09555	904-969	SAM_EPH-B6
cd14043	644-870	PK_GC-2D
cd14137	609-814	STKc_GSK3
cd06641	598-865	STKc_MST3
cd08220	613-872	STKc_Nek8
cd14097	621-835	STKc_STK33
cd09549	904-971	SAM_EPH-A10
pfam07647	904-969	SAM_2
cd07855	609-902	STKc_ERK5
cd14159	621-820	STKc_IRAK1
cd06621	616-881	PKc_Pek1_like
cd06643	621-864	STKc_SLK
cd14144	621-877	STKc_BMPR1
cd14143	619-879	STKc_TGFbR1_ACVR1b_ACVR1c
cd14193	615-833	STKc_MLCK4
cd14162	619-861	STKc_TSSK4-like
cd06608	619-842	STKc_myosinIII_N_like
cd06644	611-888	STKc_STK10
cd14010	614-872	STKc_ULK4
cd14071	614-840	STKc_SIK
cd06658	598-841	STKc_PAK5
cd14077	619-827	STKc_Kin1_2
cd06642	614-865	STKc_STK25
cd08225	619-865	STKc_Nek5
cd14166	619-837	STKc_CaMKI_gamma
cd09547	909-969	SAM_EPH-A6
cd05076	661-874	PTK_Tyk2_rpt1
cd05077	639-871	PTK_Jak1_rpt1
cd14142	619-864	STKc_ACVR1_ALK1
cd14168	616-895	STKc_CaMKI_delta
cd08530	616-865	STKc_CNK2-like
cd14156	621-877	PKc_LIMK_like_unk
cd14194	614-837	STKc_DAPK1
cd06624	605-826	STKc_ASK
cd14160	621-875	PK_IRAK3
cd14105	614-833	STKc_DAPK
pfam14575	564-612	EphA2_TM
cl22928	564-612	EphA2_TM superfamily
cd14152	615-877	STKc_KSR1
cd14165	644-845	STKc_TSSK1_2-like
cd06657	621-904	STKc_PAK4
cd08528	619-872	STKc_Nek10
cd14196	614-833	STKc_DAPK2
cd05581	616-845	STKc_PDK1
cd14039	621-821	STKc_IKK_alpha
cd14098	617-865	STKc_Rad53_Cds1
cd13994	621-828	STKc_HAL4_like
cd06630	664-865	STKc_MEKK1
cd08223	613-872	STKc_Nek4
cd07841	614-814	STKc_CDK7
cd14001	664-876	PKc_TOPK
cd07851	609-812	STKc_p38
cd14208	619-875	PTK_Jak3_rpt1
cd06619	615-821	PKc_MKK5
cd14192	619-833	STKc_MLCK3
cd05578	616-835	STKc_Yank1
cd05612	621-823	STKc_PRKX_like
cd06917	619-833	STKc_NAK1_like
cd07859	616-815	STKc_TDY_MAPK
cd14079	616-823	STKc_AMPK_alpha
cd14072	616-857	STKc_MARK
cd14076	621-823	STKc_Kin4
cd06626	621-866	STKc_MEKK4
cd14083	616-833	STKc_CaMKI
cd07832	616-814	STKc_CCRK
cd14045	670-877	PK_GC_unk
cd07852	616-856	STKc_MAPK15-like
cd07864	612-827	STKc_CDK12
cd14106	618-835	STKc_DRAK
cd07849	616-815	STKc_ERK1_2_like
cd09543	909-972	SAM_EPH-A2
cd14069	615-823	STKc_Chk1
cd13986	657-878	STKc_16
cd14195	614-837	STKc_DAPK3
cd05582	620-833	STKc_RSK_N
cd14006	621-842	STKc_MLCK-like
cd14068	620-875	STKc_LRRK2
cd13983	614-821	STKc_WNK
cd13982	618-870	STKc_IRE1
cd06622	616-870	PKc_PBS2_like
cd08228	616-865	STKc_Nek6
cd14087	617-823	STKc_PSKH1
cd14082	618-843	STKc_PKD
cd08229	593-877	STKc_Nek7
cd14191	617-831	STKc_MLCK1
cd08218	614-878	STKc_Nek1
cd07856	609-899	STKc_Sty1_Hog1
cd06613	616-865	STKc_MAP4K3_like
cd07865	606-812	STKc_CDK9
cd13985	615-876	STKc_GAK_like
cd14044	633-877	PK_GC-C
cd06625	620-875	STKc_MEKK3_like
cd13990	621-830	STKc_TLK
cd07836	613-897	STKc_Pho85
cd07838	614-820	STKc_CDK4_6_like
cd06618	609-869	PKc_MKK7
cd14186	616-840	STKc_PLK4
cd14075	612-821	STKc_NIM1
cd14116	616-841	STKc_Aurora-A
cd14114	614-821	STKc_Twitchin_like
cd14095	616-842	STKc_DCKL
cd06633	592-864	STKc_TAO3
cd07845	621-814	STKc_CDK10
cd08221	613-865	STKc_Nek9
cd07858	609-814	STKc_TEY_MAPK
cd14088	619-828	STKc_CaMK_like
cd07871	613-820	STKc_PCTAIRE3
cd14067	630-872	STKc_LRRK1
cd06617	615-870	PKc_MKK3_6
cd07879	594-901	STKc_p38delta
cd14220	621-877	STKc_BMPR1a
cd07880	601-926	STKc_p38gamma
cd14184	616-833	STKc_DCKL2
cd14209	620-840	STKc_PKA
cd05602	607-864	STKc_SGK1
cd14169	613-842	STKc_CaMKI_beta
cd14133	616-842	PKc_DYRK_like
cd14175	617-821	STKc_RSK1_C
pfam00041	435-518	fn3
cd14089	614-811	STKc_MAPKAPK
cd05579	621-848	STKc_MAST_like
cd14665	621-823	STKc_SnRK2-3
cd09542	909-966	SAM_EPH-A1
cd14172	618-839	STKc_MAPKAPK3
cd14091	617-821	STKc_RSK_C
cd07860	613-815	STKc_CDK2_3
cd07877	609-926	STKc_p38alpha
cd06607	621-865	STKc_TAO
cd14176	616-821	STKc_RSK2_C
cd14179	618-821	STKc_MSK1_C
cd14004	613-857	STKc_PASK
cd08219	617-872	STKc_Nek3
cd14189	630-871	STKc_PLK3
cd14178	616-821	STKc_RSK3_C
cd06636	619-842	STKc_MAP4K4_6_N
cd05604	619-864	STKc_SGK3
cd14198	621-835	STKc_DRAK2
cd14119	613-870	STKc_LKB1
cd07873	613-820	STKc_PCTAIRE1
cd14177	616-826	STKc_RSK4_C
cd14093	614-822	STKc_PhKG
cd06638	616-865	STKc_myosinIIIA_N
cd14047	600-815	STKc_EIF2AK2_PKR
cd05630	620-854	STKc_GRK6
cd14164	616-821	STKc_TSSK6-like
cd07862	621-846	STKc_CDK6
cd14033	614-852	STKc_WNK4
cd07872	613-815	STKc_PCTAIRE2
cd07878	621-901	STKc_p38beta
cd14180	618-821	STKc_MSK2_C
cd07857	614-827	STKc_MPK1
cd07861	614-820	STKc_CDK1_euk
cd07863	621-872	STKc_CDK4
cd05572	621-821	STKc_cGK
cd14113	625-840	STKc_Trio_C
cd14046	619-865	STKc_EIF2AK4_GCN2_rpt2
cd05601	617-821	STKc_CRIK
cd14078	614-814	STKc_MELK
cd06637	619-881	STKc_TNIK
cd05593	611-864	STKc_PKB_gamma
cd14070	617-872	STKc_HUNK
cd14662	621-823	STKc_SnRK2
cd14188	630-871	STKc_PLK2
cd14012	673-866	PK_eIF2AK_GCN2_rpt1
cd06616	618-867	PKc_MKK4
cd05611	621-821	STKc_Rim15_like
cd14185	614-842	STKc_DCKL3
cd07848	620-870	STKc_CDKL5
cd14036	615-874	STKc_GAK
cd06635	595-836	STKc_TAO1
cd06634	598-836	STKc_TAO2
cd14170	614-822	STKc_MAPKAPK2
cd14048	619-817	STKc_EIF2AK3_PERK
cd06647	614-821	STKc_PAK_I
cd14104	617-833	STKc_Titin
cd13993	614-810	STKc_Pat1_like
cd14074	617-845	STKc_SNRK
cd14199	664-870	STKc_CaMKK2
cd05607	620-823	STKc_GRK7
cd06639	617-865	STKc_myosinIIIB_N
cd07839	613-872	STKc_CDK5
cd14183	616-811	STKc_DCKL1
cd14181	602-822	STKc_PhKG2
cd14117	608-841	STKc_Aurora-B_like
cd13988	621-833	STKc_TBK1
cd14153	615-877	PK_KSR2
cd14050	616-813	PKc_Myt1
cd05595	619-840	STKc_PKB_beta
cd06652	616-846	STKc_MEKK2
cd14085	613-823	STKc_CaMKIV
cd07869	613-814	STKc_PFTAIRE1
smart00060	434-516	FN3
cd14096	616-825	STKc_RCK1-like
cd05573	620-861	STKc_ROCK_NDR_like
cd14086	616-842	STKc_CaMKII
cd14109	659-821	PK_Unc-89_rpt1
cd05603	619-864	STKc_SGK2
cd05620	619-836	STKc_nPKC_delta
cd14031	614-826	STKc_WNK3
cd05632	620-821	STKc_GRK5
cd05584	620-843	STKc_p70S6K
cd07846	619-818	STKc_CDKL2_3
cd06645	621-841	STKc_MAP4K3
cd06653	616-846	STKc_MEKK3_like_u1
cd06654	614-821	STKc_PAK1
cd07853	621-815	STKc_NLK
cd06655	619-821	STKc_PAK2
cd14092	609-821	STKc_MSK_C
cd14182	618-822	STKc_PhKG1
cd14140	619-864	STKc_ACVR2b
cd05574	613-864	STKc_phototropin_like
cd06656	614-821	STKc_PAK3
cd14219	604-877	STKc_BMPR1b
cd05631	620-821	STKc_GRK4
cd05585	620-844	STKc_YPK1_like
cd06650	611-869	PKc_MEK1
cd05615	620-828	STKc_cPKC_alpha
cd14200	664-870	STKc_CaMKK1
cd05589	620-840	STKc_PKN
cd06615	620-820	PKc_MEK
cd07831	621-842	STKc_MOK
cd14030	611-826	STKc_WNK1
cd07850	620-812	STKc_JNK
cd14037	615-870	STKc_NAK_like
cd05594	611-840	STKc_PKB_alpha
cd07876	621-814	STKc_JNK2
cd05619	617-836	STKc_nPKC_theta
cd09498	910-970	SAM_caskin1,2_repeat2
cd06651	654-851	STKc_MEKK3
cd05577	621-821	STKc_GRK
cd14020	630-815	STKc_KIS
cd14197	621-835	STKc_DRAK1
cd14132	614-900	STKc_CK2_alpha
cd05570	724-836	STKc_PKC
cd14049	621-833	STKc_EIF2AK1_HRI
cd07874	621-852	STKc_JNK3
cd14141	619-815	STKc_ACVR2a
cd14041	620-843	STKc_TLK2
cd14032	614-826	STKc_WNK2_like
cd05592	620-821	STKc_nPKC_theta_like
cd07842	616-815	STKc_CDK8_like
cd06646	621-841	STKc_MAP4K5
cd14040	620-830	STKc_TLK1
cd09544	908-970	SAM_EPH-A3
cd14094	617-842	STKc_CASK
cd05571	619-828	STKc_PKB
cd05616	724-821	STKc_cPKC_beta
cd07847	614-822	STKc_CDKL1_4
cd07835	614-812	STKc_CDK1_CdkB_like
cd07870	613-814	STKc_PFTAIRE2
cd14118	664-870	STKc_CAMKK
cd05575	620-864	STKc_SGK
cd05596	596-825	STKc_ROCK
cd09491	911-966	SAM_Ship2
cd14018	673-865	STKc_PINK1
cd05624	616-840	STKc_MRCK_beta
cd06649	611-820	PKc_MEK2
cd14138	619-749	PTKc_Wee1a
cd13991	612-845	STKc_NIK
cd14115	621-841	STKc_Kalirin_C
cd14051	619-865	PTKc_Wee1
cd08226	671-824	PK_STRAD_beta
cd07854	662-815	STKc_MAPK4_6
cd14163	616-823	STKc_TSSK3-like
cd05590	619-836	STKc_nPKC_eta
cd14187	657-865	STKc_PLK1
cd08216	660-865	PK_STRAD
cd09527	910-969	SAM_Samd5
pfam00041	325-412	fn3
smart00060	324-412	FN3
cd13410	268-321	TNFRSF9
cl22855	268-321	TNFRSF superfamily
cd15834	239-320	TNFRSF1A_teleost
cd13416	253-321	TNFRSF16
cd13423	241-309	TNFRSF6_teleost
cd00185	253-320	TNFRSF
cd10577	255-297	TNFRSF1B
pfam07714	615-874	Pkinase_Tyr
smart00454	904-971	SAM
smart00219	615-874	TyrKc
smart00221	615-874	STYKc
smart00220	616-870	S_TKc
pfam00069	616-871	Pkinase
COG0515	616-885	SPS1
PLN00034	621-899	PLN00034
PHA03209	604-816	PHA03209
PTZ00024	609-815	PTZ00024
PTZ00263	616-825	PTZ00263
PHA03212	636-813	PHA03212
PTZ00426	592-822	PTZ00426
PTZ00266	593-899	PTZ00266
PHA02988	644-865	PHA02988
TIGR03903	644-841	TOMM_kin_cyc

Ontology Information

HPRD ID	144
Molecular Class	Receptor tyrosine kinase
Molecular Function	Receptor activity (GO:0004872)
Biological Process	Immune response (GO:0006955)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

Mechanism	Down-regulation/Methylation
Biomarker	-
Drug Target	-
Biological Process	Cell communication

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO