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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| FABP3 | 2170 | Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 1 | MDGI; FABP11; H-FABP; M-FABP; O-FABP |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21531130 | 2011 | Cell line : - Source : Japanees patients Sample Type : CRC tumor and Normal tissue No. of Sample : 113 Stage : TNM Stage I-IV | Peptide Nucleic Acid (PNA)-clamp real-time RT-PCR TaqMan assay | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Fatty acid binding protein family |
| Description | The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008] | Chromosome | 1 |
| Location | 1p33-p32 |
| Start | 31360418 |
| End | 31373283 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 12866 |
| OMIM ID | 134651 |
| HGNC ID | HGNC:3557 |
| Unigene ID | Hs.657242 |
| Ensembl ID | ENSG00000121769 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_001282568.1 |
|---|---|
| Exon | complement(<8331..9252) | mRNA Sequence | Download Select all |
| Length | 1097 |
Protein Information
| Protein ID | NP_004093.1 |
|---|---|
| Protein Name | Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
| Molecular Wt. (Da) | 14727 |
| Protein Sequence | Download Select all |
| Length | 133 |
| Uniprot ID | P12645 |
| Ensembl Protein ID | ENSP00000282701 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 20 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 51160 | VPS28 | 11675 | NP_898880.1 | yeast 2-hybrid | 16169070 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| PPAR signaling pathway | hsa03320 |
Structure Information
| PDB ID | 1UC6 |
|---|---|
| Resolution | - |
| Method | SOLUTION NMR |
| Chains | A |
| Molecule | Ciliary Neurotrophic Factor Receptor alpha |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00061 | 6-132 | Lipocalin |
| cl21528 | 6-132 | Lipocalin superfamily |
| pfam14651 | 5-131 | Lipocalin_7 |
Ontology Information
| HPRD ID | 208 |
|---|---|
| Molecular Class | Transport/cargo protein |
| Molecular Function | Receptor binding (GO:0005102) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.