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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| FABP6 | 2172 | fatty acid binding protein 6, ileal | 5 | I-15P, ILLBP, I-BAP, ILBP3, I-BABP, ILBP, I-BALB |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 16951225 | 2006 | Cell line : - Source : Kyushu University Hospital in Beppu, Japan. Sample Type : CRC Tumor and adjacent normal tissue No. of Sample : 186 Stage : Duke stage A,B,C. | - | Up-regulation | - | The expression of FABP6 was higher in primary colorectal cancers and adenomas than in normal epithelium, but was dramatically decreased in lymph node metastases, suggesting that FABP6 may play an important role in early carcinogenesis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Fatty acid binding protein family |
| Description | This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008] | Chromosome | 5 |
| Location | 5q23-q35 |
| Start | 159614374 |
| End | 159665729 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 51356 |
| OMIM ID | 600422 |
| HGNC ID | HGNC:3561 |
| Unigene ID | Hs.519719 |
| Ensembl ID | ENSG00000170231 |
| PharmGKB ID | PA27962 |
mRNA Information
| mRNA ID | NM_001130958.1 |
|---|---|
| Exon | join(1..88,11683..11791,26370..26453,42180..42258, 44732..44907,47454..47543,51240..51356) | mRNA Sequence | Download Select all |
| Length | 752 |
Protein Information
| Protein ID | NP_001124430.1 |
|---|---|
| Protein Name | fatty acid binding protein 6, ileal |
| Molecular Wt. (Da) | 19743 |
| Protein Sequence | Download Select all |
| Length | 177 |
| Uniprot ID | P43115 |
| Ensembl Protein ID | ENSP00000302313 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| PPAR signaling pathway | hsa03320 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam14651 | 3-128 | Lipocalin_7 |
| cl21528 | 3-128 | Lipocalin superfamily |
| pfam00061 | 8-126 | Lipocalin |
Ontology Information
| HPRD ID | 9046 |
|---|---|
| Molecular Class | Transport/cargo protein |
| Molecular Function | Ligase activity (GO:0016874) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091) |
Drug Information
| Uniprot ID | DrugBank ID | Name | Type |
|---|---|---|---|
| P51161 | DB02659 | Cholic Acid | SmallMoleculeDrug |