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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
FAM64A 54478 family with sequence similarity 64, member A  17FLJ10156, FLJ10491, CATS 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
21989182   2011Cell line : -

Source : Beaumont Hospital Dublin, US Biomax (Rockville, MD, USA)

Sample Type : -

No. of Sample : 211 cases of matched CRC and adjacent normal tissue, 296 cases of CRC

Stage : -

ImmunohistochemistryUp-regulation-CatS may be an important prognostic biomarker and predictive of response to adjuvant FU/FA in CRC.

Greater than 95% of tumours had detectable CatS expression with significantly increased staining in tumours compared with matched normal colon (P>0.001).


Gene Details



Chromosome 17 - NC_000017.11 (6444205..6451065)

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Gene Type protein coding
Gene Family
Description -  
Chromosome 17
Location 17p13.2
Start 6444205  
End 6451065  
Strand +  
Gene Sequence

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Length 6861  
OMIM ID    
HGNC ID HGNC:25483   
Unigene ID Hs.592116   
Ensembl ID ENSG00000129195   
PharmGKB ID -   

mRNA Information


mRNA ID XM_011523944.1
Exon join(1..284,872..1200,3259..3554,5108..5203,5500..5817)  
mRNA Sequence

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Length 1517  



CDS Information


   
Location join(907..1200,3259..3554,5108..5203,6158..6218)
CDS Sequence

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CCDS ID CCDS56016.1



Protein Information


      
Protein IDNP_001182157.1
Protein Namefamily with sequence similarity 64, member A
Molecular Wt. (Da)27349
Protein Sequence

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Length 248  
Uniprot IDP07942
Ensembl Protein ID ENSP00000222399  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation16
SPhosphorylation195
SPhosphorylation199
SPhosphorylation201
SPhosphorylation197
SPhosphorylation129
SPhosphorylation131
TPhosphorylation133
SPhosphorylation135

Enzyme Information


No matching records could be found.

PPi Information


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No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam073261-232  DUF1466
cl063851-232  DUF1466 superfamily
PRK1387578-175  PRK13875


Ontology Information


   
HPRD ID1034
Molecular ClassUnclassified
Molecular FunctionExtracellular matrix structural constituent (GO:0005201)
Biological ProcessCell growth and/or maintenance (GO:0008151)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO