Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
FAT4 79633 FAT atypical cadherin 4  4CDHF14, FAT-J, CDHR11 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24951259   2015Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 22 CRC and 160 cases

Stage : TNM Stage I-IV

Exome sequencingMutation-Three novel recurrently mutated genes (CDH10, FAT4 and DOCK2), exhibited high mutation prevalence and higher-than-expected number of non-silent mutations in a CRC cohort.


Gene Details



NC_000004.11 (126237003..126414087)

View Larger Image
   
Gene Type protein coding
Gene Family Cadherins / Cadherin-related
Description The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014  
Chromosome 4
Location 4q28.1
Start 126237003  
End 126414087  
Strand +  
Gene Sequence

   Download   Select all

Length 177085  
OMIM ID 612411   
HGNC ID HGNC:23109   
Unigene ID Hs.563205   
Ensembl ID ENSG00000196159   
PharmGKB ID PA134954366   

mRNA Information


mRNA ID ?NM_001291285.1
Exon  
mRNA Sequence

   Download   Select all

Length  



CDS Information


   
Location
CDS Sequence

   Download   Select all

CCDS ID CCDS3732.3



Protein Information


      
Protein IDNP_001278214.1
Protein NameFAT atypical cadherin 4
Molecular Wt. (Da)0
Protein Sequence

   Download   Select all

Length 4981  
Uniprot IDQ9BX69
Ensembl Protein ID ENSP00000254691  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation4876

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd113042159-2254  Cadherin_repeat
cl157862159-2254  CA_like superfamily
cd113041215-1311  Cadherin_repeat
cl157861215-1311  CA_like superfamily
cd113041321-1416  Cadherin_repeat
cl157861321-1416  CA_like superfamily
cd113043408-3506  Cadherin_repeat
cl157863408-3506  CA_like superfamily
cd113043093-3190  Cadherin_repeat
cl157863093-3190  CA_like superfamily
cd113042057-2150  Cadherin_repeat
cl157862057-2150  CA_like superfamily
cd11304254-349  Cadherin_repeat
cl15786254-349  CA_like superfamily
cd11304588-685  Cadherin_repeat
cl15786588-685  CA_like superfamily
cd11304693-789  Cadherin_repeat
cl15786693-789  CA_like superfamily
cd113041948-2047  Cadherin_repeat
cl157861948-2047  CA_like superfamily
cd113042369-2462  Cadherin_repeat
cl157862369-2462  CA_like superfamily
cd113041000-1096  Cadherin_repeat
cl157861000-1096  CA_like superfamily
cd113042673-2769  Cadherin_repeat
cl157862673-2769  CA_like superfamily
cd11304479-577  Cadherin_repeat
cl15786479-577  CA_like superfamily
cd113041845-1940  Cadherin_repeat
cl157861845-1940  CA_like superfamily
cd113042263-2360  Cadherin_repeat
cl157862263-2360  CA_like superfamily
cd113042776-2868  Cadherin_repeat
cl157862776-2868  CA_like superfamily
cd113041747-1837  Cadherin_repeat
cl157861747-1837  CA_like superfamily
cd113043199-3293  Cadherin_repeat
cl157863199-3293  CA_like superfamily
cd113043514-3610  Cadherin_repeat
cl157863514-3610  CA_like superfamily
cd11304899-992  Cadherin_repeat
cl15786899-992  CA_like superfamily
cd113041428-1525  Cadherin_repeat
cl157861428-1525  CA_like superfamily
cd113042988-3083  Cadherin_repeat
cl157862988-3083  CA_like superfamily
cd113042876-2979  Cadherin_repeat
cl157862876-2979  CA_like superfamily
cd113043303-3400  Cadherin_repeat
cl157863303-3400  CA_like superfamily
cd11304364-471  Cadherin_repeat
cl15786364-471  CA_like superfamily
cd113041105-1206  Cadherin_repeat
cl157861105-1206  CA_like superfamily
cd11304798-889  Cadherin_repeat
cl15786798-889  CA_like superfamily
cd113042571-2665  Cadherin_repeat
cl157862571-2665  CA_like superfamily
cd001103977-4140  LamG
cl228613977-4140  LamG superfamily
cd11304139-246  Cadherin_repeat
cl15786139-246  CA_like superfamily
cd001104245-4366  LamG
cl228614245-4366  LamG superfamily
cd113042470-2557  Cadherin_repeat
cl157862470-2557  CA_like superfamily
cd113041540-1622  Cadherin_repeat
cl157861540-1622  CA_like superfamily
cd000543862-3898  EGF_CA
cl215043862-3898  EGF_CA superfamily
cd113041634-1736  Cadherin_repeat
cl157861634-1736  CA_like superfamily
cd000543900-3936  EGF_CA
cl215043900-3936  EGF_CA superfamily
cd1130448-131  Cadherin_repeat
cl1578648-131  CA_like superfamily
cd000543939-3974  EGF_CA
cl215043939-3974  EGF_CA superfamily
cd000544429-4463  EGF_CA
cl215044429-4463  EGF_CA superfamily
cd000544166-4198  EGF_CA
cl215044166-4198  EGF_CA superfamily
smart001122178-2257  CA
smart001121338-1418  CA
pfam000282159-2250  Cadherin
smart001121233-1313  CA
smart001122691-2771  CA
smart001123112-3192  CA
pfam000281322-1410  Cadherin
pfam000282059-2145  Cadherin
smart001122073-2152  CA
pfam000283095-3185  Cadherin
pfam000283409-3501  Cadherin
pfam00028255-344  Cadherin
smart00112274-351  CA
smart001123427-3508  CA
pfam00028694-784  Cadherin
pfam000281215-1306  Cadherin
pfam00028588-680  Cadherin
smart001122387-2464  CA
smart001121019-1098  CA
smart00112712-791  CA
smart00112498-580  CA
smart00112606-687  CA
smart001121967-2049  CA
pfam000282677-2764  Cadherin
pfam000281949-2042  Cadherin
pfam000282369-2457  Cadherin
smart001122283-2362  CA
pfam000281001-1091  Cadherin
pfam000283514-3605  Cadherin
pfam00028480-573  Cadherin
smart001121763-1839  CA
smart00112916-994  CA
smart001121865-1942  CA
pfam000281748-1831  Cadherin
pfam000283202-3288  Cadherin
smart00112158-248  CA
pfam00028363-465  Cadherin
pfam000281846-1935  Cadherin
pfam000282264-2354  Cadherin
smart001122600-2667  CA
smart001122795-2870  CA
pfam000281428-1520  Cadherin
smart001122896-2981  CA
pfam022104250-4374  Laminin_G_2
smart002823997-4142  LamG
smart001121443-1527  CA
smart001121123-1208  CA
pfam022104002-4142  Laminin_G_2
pfam000282988-3080  Cadherin
smart001123010-3087  CA
pfam00028899-987  Cadherin
smart002824245-4374  LamG
smart001123533-3611  CA
smart001123217-3296  CA
pfam000282777-2863  Cadherin
smart00112823-891  CA
smart00112381-473  CA
pfam00028798-883  Cadherin
pfam000282877-2973  Cadherin
pfam000283303-3396  Cadherin
pfam000544002-4145  Laminin_G_1
pfam000282572-2660  Cadherin
smart001793862-3898  EGF_CA
smart001123322-3402  CA
pfam00028140-241  Cadherin
pfam000281541-1622  Cadherin
pfam000281105-1198  Cadherin
smart001793900-3936  EGF_CA
pfam000282471-2556  Cadherin
pfam000544250-4376  Laminin_G_1
smart001121552-1622  CA
cd000533865-3898  EGF
smart001121657-1738  CA
cd000533903-3936  EGF
pfam076453862-3892  EGF_CA
smart0011270-133  CA
smart001813865-3898  EGF
smart001793939-3974  EGF_CA
pfam000083866-3895  EGF
pfam0002847-125  Cadherin
pfam000281638-1731  Cadherin
pfam076453900-3930  EGF_CA
pfam000083906-3933  EGF
cd000313424-3506  CA_like
smart001813903-3936  EGF
cd000533943-3974  EGF
smart001794429-4463  EGF_CA
cd000534429-4463  EGF
cd000311746-1837  CA_like
pfam000084166-4196  EGF
pfam000083945-3972  EGF
cd000534166-4198  EGF
pfam129473913-3932  EGF_3
cd000311640-1736  CA_like
pfam129473870-3894  EGF_3
smart001794166-4198  EGF_CA
pfam000084430-4461  EGF
cd00031589-685  CA_like
pfam079743868-3897  EGF_2
pfam079744431-4462  EGF_2
smart001813943-3974  EGF


Ontology Information


   
HPRD ID11635
Molecular ClassAdhesion molecule
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO