CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
11325814	2001	Cell line : - Source : Department of Surgery, Seoul National University Hospital (Seoul, Korea) Sample Type : - No. of Sample : - Stage : -	DNA Sequencing,Mutation Analysis	Mutation	-	-

Gene Details

NC_000010.10 (123237844..123357972, complement)
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Gene Type	protein coding
Gene Family	CD molecules, "Immunoglobulin superfamily / I-set domain containing"
Description	The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
Chromosome	10
Location	10q25.3-q2
Start	123237844
End	123357972
Strand	-
Gene Sequence	Download Select all
Length	120129
OMIM ID	176943
HGNC ID	HGNC:3689
Unigene ID	Hs.533683
Ensembl ID	ENSG00000066468
PharmGKB ID	PA28128

mRNA Information

mRNA ID	NM_001144918.1
Exon	join(199..695,4690..4948,47198..47367,59942..60065, 78488..78678,81194..81338,83338..83534,94716..94867, 97710..97831,100052..100162,101935..102125,110544..110666, 111233..111303,113125..113262,114854..114959, 118636..120327)
mRNA Sequence	Download Select all
Length	4303

CDS Information

Location	648..2762
CDS Sequence	Download Select all
CCDS ID	CCDS31298.1

Protein Information

Protein ID	NP_001138390.1
Protein Name	fibroblast growth factor receptor 2
Molecular Wt. (Da)	0
Protein Sequence	Download Select all
Length	704
Uniprot ID	Q15269
Ensembl Protein ID	ENSP00000291576

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Phosphorylation	769
Y	Phosphorylation	779
Y	Phosphorylation	783
Y	Phosphorylation	812
Y	Phosphorylation	770
Y	Phosphorylation	780
Y	Phosphorylation	784
Y	Phosphorylation	813

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
776	CACNA1D	247	NP_000711.1	in vivo	11292657
2185	PTK2B	3131	NP_004094.3	in vitro;in vivo	15105428
2246	FGF1	567	NP_000791.1	in vitro;in vivo	106 183 691 106 918 000 000 000
2250	FGF5	1307	NP_004455.2	in vivo	11876253
2252	FGF7	1022	NP_002000.1	in vivo	7687739
2253	FGF8	2727	NP_149353.1	in vitro	866 304 410 751 172
5335	PLCG1	1398	NP_002651.2	in vivo	7999363
8074	FGF23	5648	NP_065689.1	in vitro	12032146
8817	FGF18	4766	NP_387498.1	in vitro	10751172
8822	FGF17	4765	NP_003858.1	in vitro	10751172
10298	PAK4	5675	NP_005875.1	in vitro;in vivo;yeast 2-hybrid	12529371

Pathway Information

Pathway Name	Pathway ID
Central carbon metabolism in cancer	hsa05230
Endocytosis	hsa04144
MAPK signaling pathway	hsa04010
Pathways in cancer	hsa05200
PI3K-Akt signaling pathway	hsa04151
Prostate cancer	hsa05215
Rap1 signaling pathway	hsa04015
Ras signaling pathway	hsa04014
Regulation of actin cytoskeleton	hsa04810
Signaling pathways regulating pluripotency of stem cells	hsa04550

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd05101	456-768	PTKc_FGFR2
cl21453	456-768	PKc_like superfamily
cd05857	164-248	Ig2_FGFR
cl11960	164-248	Ig superfamily
cd05858	271-360	Ig3_FGFR-2
cl11960	271-360	Ig superfamily
cd04973	47-124	Ig1_FGFR
cl11960	47-124	Ig superfamily
cd05100	468-801	PTKc_FGFR3
cd05053	468-762	PTKc_FGFR
cd05099	468-782	PTKc_FGFR4
cd05098	467-768	PTKc_FGFR1
cd00192	485-758	PTKc
cd05054	473-757	PTKc_VEGFR
cd05103	473-761	PTKc_VEGFR2
cd05055	467-754	PTKc_PDGFR
cd05102	473-761	PTKc_VEGFR3
cd05045	480-761	PTKc_RET
cd14207	473-757	PTKc_VEGFR1
cd05106	467-761	PTKc_CSF-1R
cd05104	467-761	PTKc_Kit
cd05107	463-762	PTKc_PDGFR_beta
cd05032	474-759	PTKc_InsR_like
cd05105	463-761	PTKc_PDGFR_alpha
cd05044	487-757	PTKc_c-ros
cd05039	474-760	PTKc_Csk_like
cd05036	475-758	PTKc_ALK_LTK
cd05047	487-761	PTKc_Tie
cd05034	485-758	PTKc_Src_like
cd05148	474-760	PTKc_Srm_Brk
cd05048	475-753	PTKc_Ror
cd05089	487-761	PTKc_Tie1
cd05050	475-759	PTKc_Musk
cd05049	475-757	PTKc_Trk
cd05038	476-761	PTKc_Jak_rpt2
cd05056	474-761	PTKc_FAK
cd05068	473-753	PTKc_Frk_like
cd05088	487-761	PTKc_Tie2
cd05051	475-753	PTKc_DDR
cd05061	474-757	PTKc_InsR
cd05052	474-758	PTKc_Abl
cd05060	485-761	PTKc_Syk_like
cd05035	481-761	PTKc_TAM
cd05083	474-759	PTKc_Chk
cd05041	487-758	PTKc_Fes_like
cd05059	481-757	PTKc_Tec_like
cd05082	474-760	PTKc_Csk
cd13999	487-757	STKc_MAP3K-like
cd05057	475-761	PTKc_EGFR_like
cd05062	474-757	PTKc_IGF-1R
cd14204	478-761	PTKc_Mer
cd05046	476-757	PTK_CCK4
cd05075	480-761	PTKc_Axl
cd05058	487-761	PTKc_Met_Ron
cd05033	481-761	PTKc_EphR
cd05092	478-753	PTKc_TrkA
cd05043	478-757	PTK_Ryk
cd05074	477-761	PTKc_Tyro3
cd05085	484-757	PTKc_Fer
cd05040	485-757	PTKc_Ack_like
cd05072	474-767	PTKc_Lyn
cd05095	475-753	PTKc_DDR2
cd05084	484-757	PTKc_Fes
cd05097	475-753	PTKc_DDR_like
cd05067	473-762	PTKc_Lck_Blk
cd05091	487-753	PTKc_Ror2
cd05093	478-753	PTKc_TrkB
cd00180	487-757	PKc
cd05090	475-753	PTKc_Ror1
cd05109	485-760	PTKc_HER2
cd05066	480-761	PTKc_EphR_A
cd05063	481-761	PTKc_EphR_A2
cd05094	478-753	PTKc_TrkC
cd05113	477-754	PTKc_Btk_Bmx
cd05108	475-801	PTKc_EGFR
cd05112	479-757	PTKc_Itk
cd05096	475-753	PTKc_DDR1
cd05073	470-753	PTKc_Hck
cd04974	271-360	Ig3_FGFR
cd05079	485-761	PTKc_Jak1_rpt2
cd05114	480-761	PTKc_Tec_Rlk
cd05116	485-750	PTKc_Syk
cd05069	474-781	PTKc_Yes
cd05065	487-761	PTKc_EphR_B
cd05115	478-750	PTKc_Zap-70
cd14205	476-760	PTKc_Jak2_rpt2
cd14203	485-753	PTKc_Src_Fyn_like
cd05729	164-248	Ig2_FGFR_like
cd05071	474-781	PTKc_Src
cd05081	487-760	PTKc_Jak3_rpt2
cd05080	476-757	PTKc_Tyk2_rpt2
cd05070	474-781	PTKc_Fyn
cd05111	476-760	PTK_HER3
cd05110	485-760	PTKc_HER4
cd05064	475-761	PTKc_EphR_A10
cd06606	480-756	STKc_MAPKKK
cd14059	513-758	STKc_MAP3K12_13
cd14061	487-760	STKc_MLK
cd14060	488-758	STKc_MLTK
cd14058	487-754	STKc_TAK1
cd14206	487-753	PTKc_Aatyk3
cd05122	480-753	PKc_STE
cd14145	480-760	STKc_MLK1
cd14146	487-760	STKc_MLK4
cd05042	485-762	PTKc_Aatyk
cd14148	487-760	STKc_MLK2
cd06627	480-753	STKc_Cdc7_like
cd14147	480-758	STKc_MLK3
cd13968	487-646	PKc_like
cd05087	485-753	PTKc_Aatyk1
cd14066	487-760	STKc_IRAK
cd14003	482-756	STKc_AMPK-like
cd13978	487-759	STKc_RIP
cd14065	487-757	PKc_LIMK_like
cd06632	484-755	STKc_MEKK1_plant
cd14007	483-755	STKc_Aurora
cd06614	485-756	STKc_PAK
cd14014	482-759	STKc_PknB_like
cd14099	484-756	STKc_PLK
cd08215	487-753	STKc_Nek
cd14002	479-703	STKc_STK36
cd05117	482-756	STKc_CAMK
cd13992	513-760	PK_GC
cd14154	487-760	STKc_LIMK
cd07833	482-717	STKc_CDKL
cd08225	485-755	STKc_Nek5
cd14151	474-760	STKc_B-Raf
cd08530	485-753	STKc_CNK2-like
cd14000	487-757	STKc_LRRK
cd06609	487-753	STKc_MST3_like
cd14027	531-755	STKc_RIP1
cd14062	487-758	STKc_Raf
cd07829	487-714	STKc_CDK_like
cd06611	477-756	STKc_SLK_like
cd14155	487-761	PKc_TESK
cd06624	465-756	STKc_ASK
cd06625	483-753	STKc_MEKK3_like
cd06612	487-756	STKc_MST1_2
cd06623	481-755	PKc_MAPKK_plant_like
cd13979	483-749	STKc_Mos
cd07830	482-753	STKc_MAK_like
cd14221	487-761	STKc_LIMK1
cd06644	487-755	STKc_STK10
cd05086	487-762	PTKc_Aatyk2
cd14009	487-739	STKc_ATG1_ULK_like
cd14069	482-693	STKc_Chk1
cd06608	477-755	STKc_myosinIII_N_like
cd08529	483-753	STKc_FA2-like
cd14121	487-752	STKc_ULK3
cd05118	485-717	STKc_CMGC
cd14080	482-693	STKc_TSSK-like
cd06610	513-755	STKc_OSR1_SPAK
cd08217	487-756	STKc_Nek2
cd05037	481-757	PTK_Jak_rpt1
cd06629	484-756	STKc_Bck1_like
cd06628	484-754	STKc_Byr2_like
cd06613	485-756	STKc_MAP4K3_like
cd14042	514-753	PK_GC-A_B
cd06643	469-755	STKc_SLK
cd08218	485-755	STKc_Nek1
cd14008	487-753	STKc_LKB1_CaMKK
cd14156	516-760	PKc_LIMK_like_unk
cd14158	478-760	STKc_IRAK4
cd14202	473-725	STKc_ULK1
cd14222	487-763	STKc_LIMK2
cd07840	487-706	STKc_CDK9_like
cd13996	487-757	STKc_EIF2AK
cd14150	480-760	STKc_A-Raf
cd14063	481-760	PK_KSR
cd05619	479-725	STKc_nPKC_theta
cd05570	485-713	STKc_PKC
cd14162	482-721	STKc_TSSK4-like
cd14149	474-758	STKc_C-Raf
cd14116	479-755	STKc_Aurora-A
cd08228	485-748	STKc_Nek6
cd06641	487-755	STKc_MST3
cd14072	480-756	STKc_MARK
cd05123	487-732	STKc_AGC
cd14064	487-758	PKc_TNNI3K
cd05582	485-747	STKc_RSK_N
cd14084	478-755	STKc_Chk2
cd14119	487-753	STKc_LKB1
cd13993	480-754	STKc_Pat1_like
cd08219	485-749	STKc_Nek3
cd06640	477-755	STKc_MST4
cd06642	477-755	STKc_STK25
cd06917	487-753	STKc_NAK1_like
cd08224	482-749	STKc_Nek6_7
cd07834	485-698	STKc_MAPK
cd14075	482-756	STKc_NIM1
cd14071	485-753	STKc_SIK
cd07860	487-782	STKc_CDK2_3
cd05616	487-747	STKc_cPKC_beta
cd05581	484-703	STKc_PDK1
cd06637	477-755	STKc_TNIK
cd14161	487-753	STKc_NUAK2
cd06636	477-755	STKc_MAP4K4_6_N
cd07862	487-697	STKc_CDK6
cd06605	487-755	PKc_MAPKK
cd07841	482-714	STKc_CDK7
cd07851	474-706	STKc_p38
cd13994	487-756	STKc_HAL4_like
cd14073	485-749	STKc_NUAK
cd05580	479-703	STKc_PKA_like
cd14165	483-755	STKc_TSSK1_2-like
cd14078	487-755	STKc_MELK
cd07835	487-782	STKc_CDK1_CdkB_like
cd05592	485-713	STKc_nPKC_theta_like
cd07832	483-706	STKc_CCRK
cd07836	487-781	STKc_Pho85
cd14079	482-719	STKc_AMPK_alpha
cd14189	484-755	STKc_PLK3
cd14137	480-706	STKc_GSK3
cd07847	483-792	STKc_CDKL1_4
cd14188	484-755	STKc_PLK2
cd14068	487-758	STKc_LRRK2
cd05620	485-725	STKc_nPKC_delta
cd07863	487-697	STKc_CDK4
cd08229	485-748	STKc_Nek7
cd05589	487-713	STKc_PKN
cd14081	483-752	STKc_BRSK1_2
cd14025	487-763	STKc_RIP4_like
cd06631	482-753	STKc_YSK4
cd14664	487-760	STK_BAK1_like
cd05584	485-706	STKc_p70S6K
cd14050	487-753	PKc_Myt1
cd06622	479-755	PKc_PBS2_like
cd13983	487-704	STKc_WNK
cd06655	477-781	STKc_PAK2
cd07848	487-717	STKc_CDKL5
cd14120	487-725	STKc_ULK1_2-like
cd14056	485-749	STKc_TGFbR_I
cd07838	487-699	STKc_CDK4_6_like
cd13997	487-754	PKc_Wee1_like
cd08223	482-756	STKc_Nek4
cd08221	487-755	STKc_Nek9
cd14044	503-762	PK_GC-C
cd14004	485-756	STKc_PASK
cd07877	474-706	STKc_p38alpha
cd07878	474-706	STKc_p38beta
cd14152	480-763	STKc_KSR1
cd14052	480-761	PTKc_Wee1_fungi
cd06620	477-754	PKc_Byr1_like
cd07846	482-757	STKc_CDKL2_3
cd06647	477-704	STKc_PAK_I
cd06626	484-756	STKc_MEKK4
cd07873	487-731	STKc_PCTAIRE1
cd06645	477-755	STKc_MAP4K3
cd14070	483-756	STKc_HUNK
cd07842	488-699	STKc_CDK8_like
cd14098	487-752	STKc_Rad53_Cds1
cd06648	477-755	STKc_PAK_II
cd14117	475-704	STKc_Aurora-B_like
cd14048	487-755	STKc_EIF2AK3_PERK
cd14097	482-755	STKc_STK33
cd07857	485-717	STKc_MPK1
cd06654	477-781	STKc_PAK1
cd13998	488-749	STKc_TGFbR-like
cd14043	543-753	PK_GC-2D
cd05587	487-731	STKc_cPKC
cd13975	525-762	PKc_Dusty
cd06638	477-755	STKc_myosinIIIA_N
cd14208	481-758	PTK_Jak3_rpt1
cd07839	487-716	STKc_CDK5
cd06630	484-753	STKc_MEKK1
cd14167	478-725	STKc_CaMKI_alpha
cd05615	487-747	STKc_cPKC_alpha
cd14076	483-694	STKc_Kin4
cd14663	480-756	STKc_SnRK3
cd06652	483-698	STKc_MEKK2
cd06653	483-698	STKc_MEKK3_like_u1
cd06656	477-781	STKc_PAK3
cd07831	483-755	STKc_MOK
cd06633	487-754	STKc_TAO3
cd08222	485-749	STKc_Nek11
cd06635	463-755	STKc_TAO1
cd14026	512-761	STKc_RIP2
cd05078	487-758	PTK_Jak2_rpt1
cd07861	487-782	STKc_CDK1_euk
cd07865	487-698	STKc_CDK9
cd05578	488-706	STKc_Yank1
cd14045	513-760	PK_GC_unk
cd07866	483-698	STKc_BUR1
cd14077	483-755	STKc_Kin1_2
cd13989	487-718	STKc_IKK
cd08528	487-699	STKc_Nek10
cd07871	483-731	STKc_PCTAIRE3
cd14012	520-753	PK_eIF2AK_GCN2_rpt1
cd14046	485-700	STKc_EIF2AK4_GCN2_rpt2
cd14095	480-720	STKc_DCKL
cd14175	515-755	STKc_RSK1_C
cd14186	487-755	STKc_PLK4
cd06646	477-754	STKc_MAP4K5
cd13987	487-698	STKc_SBK1
cd14187	544-756	STKc_PLK1
cd05572	487-706	STKc_cGK
cd07872	487-731	STKc_PCTAIRE2
cd14006	487-706	STKc_MLCK-like
cd07849	487-706	STKc_ERK1_2_like
cd07845	487-706	STKc_CDK10
cd06607	487-691	STKc_TAO
cd14103	487-706	STKc_MLCK
cd14164	482-753	STKc_TSSK6-like
cd06639	477-715	STKc_myosinIIIB_N
cd05579	490-713	STKc_MAST_like
cd08220	513-753	STKc_Nek8
cd14053	513-698	STKc_ACVR2
cd14143	487-749	STKc_TGFbR1_ACVR1b_ACVR1c
cd07880	474-698	STKc_p38gamma
cd06621	479-712	PKc_Pek1_like
cd07850	485-706	STKc_JNK
cd07854	485-718	STKc_MAPK4_6
cd14209	479-747	STKc_PKA
cd14144	485-749	STKc_BMPR1
cd06617	479-755	PKc_MKK3_6
cd14118	544-717	STKc_CAMKK
cd14054	513-711	STKc_BMPR2_AMHR2
cd13985	485-757	STKc_GAK_like
cd05077	481-758	PTK_Jak1_rpt1
cd14178	515-778	STKc_RSK3_C
cd05856	164-248	Ig2_FGFRL1-like
cd14199	534-704	STKc_CaMKK2
cd14010	560-712	STKc_ULK4
cd14093	503-703	STKc_PhKG
cd06651	484-698	STKc_MEKK3
cd14192	487-706	STKc_MLCK3
cd14201	474-726	STKc_ULK2
cd14039	487-695	STKc_IKK_alpha
cd05611	485-714	STKc_Rim15_like
cd07837	487-782	STKc_CdkB_plant
cd06634	485-755	STKc_TAO2
cd06659	477-755	STKc_PAK6
cd07879	474-698	STKc_p38delta
cd07864	479-698	STKc_CDK12
cd14055	487-696	STKc_TGFbR2_like
cd14185	483-720	STKc_DCKL3
cd14166	487-720	STKc_CaMKI_gamma
cd14142	480-761	STKc_ACVR1_ALK1
cd06658	477-756	STKc_PAK5
cd14083	478-725	STKc_CaMKI
cd14197	478-713	STKc_DRAK1
cd14067	505-755	STKc_LRRK1
cd07844	486-782	STKc_PCTAIRE_like
cd05595	485-747	STKc_PKB_beta
cd14210	487-706	PKc_DYRK
cd14047	486-697	STKc_EIF2AK2_PKR
cd00096	175-245	Ig
cd07853	607-696	STKc_NLK
cd07870	485-715	STKc_PFTAIRE2
cd13982	485-752	STKc_IRE1
cd14177	511-755	STKc_RSK4_C
cd14057	514-760	PK_ILK
cd14169	482-725	STKc_CaMKI_beta
cd07856	485-706	STKc_Sty1_Hog1
cd14200	528-704	STKc_CaMKK1
cd13995	480-755	STKc_MAP3K8
cd14153	480-760	PK_KSR2
cd05591	485-713	STKc_nPKC_epsilon
cd07858	608-706	STKc_TEY_MAPK
cd14184	479-704	STKc_DCKL2
cd14106	484-713	STKc_DRAK
cd14190	487-706	STKc_MLCK2
cd14220	485-760	STKc_BMPR1a
cd06619	514-755	PKc_MKK5
cd14159	487-698	STKc_IRAK1
cd14094	530-755	STKc_CASK
cd14091	515-755	STKc_RSK_C
cd14111	602-704	STKc_SPEG_rpt2
cd07855	608-696	STKc_ERK5
cd06616	474-706	PKc_MKK4
cd07852	480-706	STKc_MAPK15-like
cd07843	608-718	STKc_CDC2L1
cd14176	515-708	STKc_RSK2_C
cd14193	487-706	STKc_MLCK4
cd14074	483-745	STKc_SNRK
cd14198	485-713	STKc_DRAK2
cd14168	487-752	STKc_CaMKI_delta
cd05590	487-714	STKc_nPKC_eta
cd14037	478-699	STKc_NAK_like
cd14141	513-696	STKc_ACVR2a
cd05630	613-719	STKc_GRK6
cd14038	487-704	STKc_IKK_beta
cd14036	480-760	STKc_GAK
cd14011	608-704	PK_SCY1_like
cd14086	479-704	STKc_CaMKII
cd14194	483-706	STKc_DAPK1
cd05612	479-703	STKc_PRKX_like
cd07874	485-696	STKc_JNK3
cd14135	486-698	STKc_PRP4
cd05571	485-716	STKc_PKB
cd06657	477-755	STKc_PAK4
cd14131	485-753	PKc_Mps1
cd05593	485-716	STKc_PKB_gamma
cd06615	547-705	PKc_MEK
cd14001	515-699	PKc_TOPK
cd05613	483-704	STKc_MSK1_N
cd05604	485-819	STKc_SGK3
cd14183	479-706	STKc_DCKL1
cd06649	547-712	PKc_MEK2
cd14087	487-704	STKc_PSKH1
cd14219	480-749	STKc_BMPR1b
cd05602	485-697	STKc_SGK1
cd14110	513-705	STKc_obscurin_rpt2
cd05728	174-248	Ig4_Contactin-2-like
cd07875	485-706	STKc_JNK1
cd14049	487-755	STKc_EIF2AK1_HRI
cd05632	487-706	STKc_GRK5
cd06650	547-712	PKc_MEK1
cd14019	487-698	STKc_Cdc7
cd05725	175-248	Ig3_Robo
cd05609	560-713	STKc_MAST
cd05617	487-718	STKc_aPKC_zeta
cd05594	477-716	STKc_PKB_alpha
cd05750	178-243	Ig_Pro_neuregulin
cd07859	608-706	STKc_TDY_MAPK
cd05577	583-704	STKc_GRK
cd05618	483-704	STKc_aPKC_iota
cd14105	479-713	STKc_DAPK
cd14033	487-705	STKc_WNK4
cd05631	609-704	STKc_GRK4
cd05076	493-757	PTK_Tyk2_rpt1
cd05608	583-701	STKc_GRK1
cd05586	487-719	STKc_Sck1_like
cd14163	483-694	STKc_TSSK3-like
cd05573	483-704	STKc_ROCK_NDR_like
cd05614	483-704	STKc_MSK2_N
cd14114	479-706	STKc_Twitchin_like
cd14195	479-711	STKc_DAPK3
cd14090	480-706	STKc_Mnk
cd00096	274-356	Ig
cd14109	531-719	PK_Unc-89_rpt1
cd14196	479-706	STKc_DAPK2
cd13977	560-759	STKc_PDIK1L
cd07869	487-707	STKc_PFTAIRE1
cd05603	485-713	STKc_SGK2
cd14140	514-698	STKc_ACVR2b
cd14179	485-719	STKc_MSK1_C
cd14113	487-711	STKc_Trio_C
cd07876	485-696	STKc_JNK2
cd14132	465-697	STKc_CK2_alpha
cd14096	482-703	STKc_RCK1-like
cd14191	487-706	STKc_MLCK1
cd08216	482-691	PK_STRAD
cd14133	487-706	PKc_DYRK_like
cd14182	532-703	STKc_PhKG1
cd05607	583-704	STKc_GRK7
pfam00047	173-233	ig
cd14112	477-711	STKc_Unc-89_rpt2
cd05605	609-704	STKc_GRK4_like
cd14082	487-694	STKc_PKD
cd05622	485-704	STKc_ROCK1
cd14181	515-703	STKc_PhKG2
cd05621	485-704	STKc_ROCK2
cd14174	487-706	STKc_Mnk1
cd05583	487-704	STKc_MSK_N
cd13990	487-756	STKc_TLK
cd14665	543-704	STKc_SnRK2-3
cd14173	487-706	STKc_Mnk2
cd05624	478-730	STKc_MRCK_beta
cd14088	479-704	STKc_CaMK_like
cd08226	514-712	PK_STRAD_beta
cd14085	479-704	STKc_CaMKIV
cd05588	485-704	STKc_aPKC
cd06618	607-755	PKc_MKK7
cd04978	174-249	Ig4_L1-NrCAM_like
cd13986	534-758	STKc_16
cd14031	487-754	STKc_WNK3
cd14104	480-706	STKc_Titin
cd14212	487-706	PKc_YAK1
cd05747	169-238	Ig5_Titin_like
cd05598	623-703	STKc_LATS
cd04967	175-240	Ig1_Contactin
cd05585	558-718	STKc_YPK1_like
cd14018	539-749	STKc_PINK1
cd14005	483-755	STKc_PIM
cd05731	179-248	Ig3_L1-CAM_like
cd14180	534-706	STKc_MSK2_C
cd05610	479-708	STKc_MASTL
cd14172	614-754	STKc_MAPKAPK3
cd14170	610-793	STKc_MAPKAPK2
cd07693	169-238	Ig1_Robo
cd05600	487-717	STKc_Sid2p_like
cd05731	286-359	Ig3_L1-CAM_like
cd05725	274-359	Ig3_Robo
pfam00047	271-342	ig
cd00096	58-110	Ig
cd05731	70-124	Ig3_L1-CAM_like
pfam07714	481-757	Pkinase_Tyr
smart00408	173-238	IGc2
smart00410	263-359	IG_like
smart00408	54-110	IGc2
smart00221	481-757	STYKc
smart00219	481-757	TyrKc
smart00220	482-756	S_TKc
pfam00069	481-756	Pkinase
COG0515	482-804	SPS1
PTZ00024	483-706	PTZ00024
PTZ00267	508-755	PTZ00267
PHA02988	514-757	PHA02988
PTZ00426	485-704	PTZ00426
smart00409	174-248	IG
smart00410	174-248	IG_like
PLN00009	487-717	PLN00009
pfam07679	174-248	I-set
smart00409	263-359	IG
PTZ00263	466-704	PTZ00263
PTZ00283	562-754	PTZ00283
PTZ00036	477-781	PTZ00036
PTZ00266	485-752	PTZ00266
PHA03209	482-696	PHA03209
PLN00034	534-755	PLN00034
pfam07679	263-359	I-set
PRK13184	487-704	pknD
smart00410	47-124	IG_like
smart00409	47-124	IG
PHA03212	532-698	PHA03212
TIGR03903	514-698	TOMM_kin_cyc
smart00408	271-349	IGc2
pfam07679	44-110	I-set

Ontology Information

HPRD ID	1528
Molecular Class	Receptor tyrosine kinase
Molecular Function	Oxidoreductase activity (GO:0016491)
Biological Process	Metabolism (GO:0008152); Energy pathways (GO:0006091)

SNP Information

View SNP Geneview Report

Uniprot ID	DrugBank ID	Name	Type
P21802	DB00039	Palifermin	BiotechDrug
P21802	DB01041	Thalidomide	SmallMoleculeDrug
P21802	DB08896	Regorafenib	SmallMoleculeDrug
P21802	DB08901	Ponatinib	SmallMoleculeDrug
P21802	DB09078	Lenvatinib	SmallMoleculeDrug
P21802	DB09079	Nintedanib	SmallMoleculeDrug