Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| FMNL3 | 91010 | formin-like 3 | 12 | DKFZp762B245, MGC45819, WBP3 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25758200 | 2015 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 96 Stage : - | Immunohistochemistry, Univariate and multivariate analyses | Up-regulation | - | FMNL3 plays an important role in the progression and metastasis of CRC and may be a novel potential prognostic predictor and therapeutic target for patients with CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] | Chromosome | 12 |
| Location | 12q13.12 |
| Start | 50031724 |
| End | 50101197 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 69474 |
| OMIM ID | - |
| HGNC ID | HGNC:23698 |
| Unigene ID | Hs.179838 |
| Ensembl ID | - |
| PharmGKB ID | PA134992328 |
Protein Information
| Protein ID | NP_783863.4 |
|---|---|
| Protein Name | formin-like 3 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1028 |
| Uniprot ID | Q9BZQ8 |
| Ensembl Protein ID | ENSP00000356481 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 174 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 55660 | PRPF40A | 10995 | NP_060362.3 | in vitro;yeast 2-hybrid | 917 135 115 231 748 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam02181 | 561-926 | FH2 |
| cl19758 | 561-926 | FH2 superfamily |
| smart00498 | 562-988 | FH2 |
| pfam06367 | 281-478 | Drf_FH3 |
| cl05717 | 281-478 | Drf_FH3 superfamily |
| pfam06371 | 27-278 | Drf_GBD |
| cl05720 | 27-278 | Drf_GBD superfamily |
| pfam04111 | 354-457 | APG6 |
| pfam02994 | 384-479 | Transposase_22 |
| TIGR02169 | 352-486 | SMC_prok_A |
| COG2433 | 396-463 | COG2433 |
| pfam05483 | 355-496 | SCP-1 |
Ontology Information
| HPRD ID | 9616 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.