CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
FSCN1	6624	fascin actin-bundling protein 1	7	p55, FLJ38511

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
25302416	2014	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	-	Up-regulation	-	Fascin1 as a potent prognostic biomarker for breast, colorectal, esophageal cancers and head and neck squamous cell carcinomas.

Gene Details

Chromosome 7 - NC_000007.14 (5592805..5606656)
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Gene Type	protein coding
Gene Family	Fascins
Description	This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Chromosome	7
Location	7p22
Start	5592805
End	5606656
Strand	+
Gene Sequence	>gi\|568815591:5592805-5606656 Homo sapiens chromosome 7, GRCh38.p2 Primary Assembly AGCTGGGCTTTGTGGAGCGCTGCGGAGGGTGCGTGCGGGCCGCGGCAGCCGAACAAAGGAGCAGGGGCGC CGCCGCAGGGACCCGCCACCCACCTCCCGGGGCCGCGCAGCGGCCTCTCGTCTACTGCCACCATGACCGC CAACGGCACAGCCGAGGCGGTGCAGATCCAGTTCGGCCTCATCAACTGCGGCAACAAGTACCTGACGGCC GAGGCGTTCGGGTTCAAGGTGAACGCGTCCGCCAGCAGCCTGAAGAAGAAGCAGATCTGGACGCTGGAGC AGCCCCCTGACGAGGCGGGCAGCGCGGCCGTGTGCCTGCGCAGCCACCTGGGCCGCTACCTGGCGGCGGA CAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGGTCCCGACTGCCGTTTCCTCATCGTGGCGCAC GACGACGGTCGCTGGTCGCTGCAGTCCGAGGCGCACCGGCGCTACTTCGGCGGCACCGAGGACCGCCTGT CCTGCTTCGCGCAGACGGTGTCCCCCGCCGAGAAGTGGAGCGTGCACATCGCCATGCACCCTCAGGTCAA CATCTACAGCGTCACCCGTAAGCGCTACGCGCACCTGAGCGCGCGGCCGGCCGACGAGATCGCCGTGGAC CGCGACGTGCCCTGGGGCGTCGACTCGCTCATCACCCTCGCCTTCCAGGACCAGCGCTACAGCGTGCAGA CCGCCGACCACCGCTTCCTGCGCCACGACGGGCGCCTGGTGGCGCGCCCCGAGCCGGCCACTGGCTACAC GCTGGAGTTCCGCTCCGGCAAGGTGGCCTTCCGCGACTGCGAGGGCCGTTACCTGGCGCCGTCGGGGCCC AGCGGCACGCTCAAGGCGGGCAAGGCCACCAAGGTGGGCAAGGACGAGCTCTTTGCTCTGGAGCAGAGCT GCGCCCAGGTCGTGCTGCAGGCGGCCAACGAGAGGAACGTGTCCACGCGCCAGGGTGAGTGGGGACGCTG CCCCCGCCTCTCCTGGTCCGTGCACAAAGCGCACCCCACCCGCGCCCCTCCAGCCTCCCGCCCTTTCTCG CTCGCGGCGCCGCTGCGGTCCGGAGCACTGCCCATTGCGCCCCCGCTAGGCACGCGGGCTACCCCGCCTG GAGGGGGCGAGGAGTGGGGCTTTGCCCATCCTCGGGTGCCGCTGCCCACCTCCCACCCCGGGCTGGGATC ATGGGCTCCCCTAGGCCCCGCGGAGTCGCAACCGTACGTGCACCCTCCTAACCCCCCCCCCCGCCCAATC TTGGCTCTCCCCACGCGCGCTGATCCCTCGGATCAGCTGTCCCAGCTCTTGCGGAGTGGGAGCCCCTCAC CCATTTCCTCGTGCCCCTCCCCCCGCCGGCTGTCCTGGAGCTCGGGGGTCCGAGGCAAGGGTCGCCACCC GCAAGGGCGCGCCTCCACCCCCACCGGCAGCCTTTCGCGGGCGAGATGGGGGAGGTTAGCCAGGCCTTTG ATCCCGGCGGGGCGCGCCTCCACCTCCCCGTCTGCCCGGCCTTCCTCCACCTCCTCCCGCTGCCGGGCGG GGTCGGCCTCCGCTGGTGGGGGGGGGCGCGGGGTGTCAGCCCTTCCCCCCAGCCCCTCCTCCCGCGTCTG CCCCGCGCTCGAGGCCGCGGCCTTTGTGAGCAGGGGGGCGGGTCGCCTCGACTGGGTCCTCCCTCGCCCC CTTTGTCCTGCTCCATCTCTGCAGATGGGAAAACCAGATGCGGCGGGGCGGGGGAGGGGATCGGCTTTTG CGGTTCACCCCTGCAGAGGAGCCCCCCGCGCCGCCCCCGGGCCCAGGGCTCGGGTCCCGAGGTTCCCCAG GAGGCGGTCTCCCTCCTCGCGCCGCGGCCCGGGAACGGCGTGGCGCGGATGGCGGCCCTCCAGGCACCCC GCCCTTCGCCCGCCGCGCGCGTCTCCAGGCCGGTGCGCTGAGCTCCGCTCCGCGGGCGACCGAGGGCGGC TTCAGCGCGAGCCGGGAGACCCCAGGCCAGCTCCCTCGGGAAGCCCCTACCCTCTGGTGAACCCATCCCC TAGGGCGCTCGCCGGGAACAATTGACTGCAACTCGATCCGTCCCCTCCGGGGCCTCCTGCAGGCACGGCT ATTTGCGACCGGCCTGTGCGCCACTCTTTCCCTTCTTTCTCAGATTCTCCCCGAGGGGCTTTCTCTTCCT TTTGGCGTCCTCTTCCACTCCTGGCGGAGAAGCTGTTCCTTGCTTGCAGACAGAGGCCCCGCTGGAGGGA GGGGCGTGGGGGGATCTTTTTCCCTGGATAGGAAGTCGGACCCCAGGCCTTGGAGATGGCTGGACGGGAG CCCAGTTTGTGTCCTCATCCCTCCTCTTGGAAGGAGCCCTCCTGACGGCCCCCCTCTTGGCTGTGGGCTC TGCAGGAGGGGGAAAGACCCCCCATGGCAGTGGGGGTGAGGGTGGAGGCCTGGGTGGGGTAATGGCCATT TTGTGCCTGAAGTTTGCTACCTTAAGTCCCAGAGAGGTGAAGCTGCTTGTCATGGGTCACACAGCAAGTG ACCACAAGGAAGCAGCATGCAGAAGTGGGTGCATTTGGCTCCAGAAACCCCGTTTCCTGTTTCCCACAGC GCATGGCGGGCAGAGCTCCTCACCTGATCAGCAGGCATTGAGCCCTACTAAGGGGACCTGCTGAGCCATG AGTGAACCAGTGGGGTTCACGTTCTCTTGGGGACATTACGAAGTGTCAAGGAAAAGGCAGCGGGTACAGG TTATTAGATGGCTGAGTCCTTTCTGAGCAGGACATTTGAGCTGGCCTGAAGGATGAATAGAAGGTGGCAG GTATGGGGGGGGTGCTGTGTGGACCAGCGTTGTAGGCTGTGGGTGTCTCCTGTGCAAAGGTCTTATGGCA GGAAGGTACAGAGAAAGCCCAGTGTGGCTGGGAGGAAGCTTGTGAGGTCTGGGCCACGGGACCTTGGGTG AGAGCTTAGTGCAGGGCTATGGTCCTTGCCTTGGGGTTGCAGCCACAGCCTCCCGTGGGGAAGAAGTCGC AGAAGTAGGTGGCCTTGGCCCTGGGGGCCAGGAAGTTGCAGAGAGCCTGAGGGTGTTTTTGGCGAGCCTG GGCAGATAACTCCCCTCTCCTGAGAAGCTTGCTGGGGGCGTCTGGTGTGTGATTCAGGCTGATAGGGTGG GAGGAACCAGAAATTGCAGCCAGGAGAGGTGGTGGTGATGGCTCAGCTTGGAGTTGAAAGGGATGTGGGA CGGCGCGGGGGTGGGGGTACTTGGGGGCCGAGGTTGGGGCTCCTCTGGCCTCAGATCTTGGGGTCCTTAT CTCGTTTCTATGTCAGCCAACTCCCGGGGGGCTTTTGGGAACTGGAGTCTGCAGGGGTGGGCGTGGGGGG CGTGTCTGCAGAGGCCATTTTGGACGGGCCTGCGTGGCAAGGGGGAGGCGTCTGCTTCCGACACACATGC TGGGGAACGCCAGCCAGGAAGGGGAGGATCCGGACTTAGCTGGCAGGGGGGATGTGAATCATCTCTGCAG GCCTGCACGGGCGGGCCCGGTGGGGGCAGGGTGCTCCCCTTTGAAAAACGCTGCGCCCTGCTCTTCAGCC TCAGTTTCCCCATCTGTAAAGTGTGCATTCCAGGCCTCCTTGGGCTGGCCCAGAGCTGCCCTGGGCAGGG GCTTTCAGCCCTTCACACCAGAGGCTGGGTCAGCTGAGTGAGTGCTCCTTTGTCCTCCCGCCATGCCCCA GGCTCCTCCCTGCTCCCCAGGATCCACACCTACCCTGGCCCCGACCCTGGGCCATGCCTCACCACACTTC CTGTCTTCTCTCACATCTCTCACATCTGGGAGTCCTCTCCCGCCAGCCTGTGCTTGCATCTGGGGATCCA TGCCAGGGATAGGACCTGTCCTCCCTGCTGGCTTGGGACATGCCCTCTCCCAGCCACTCTGAGGAGGGCT GACTGAGGAAGGGCTCGTCAAGCTGGGCTTTGCAGGATGTGTAAGAGTTCTCCCCACGAGGCGCAGGGCA TTCTGAGCCCAGGGAATGGCTTGTATAAGGATGCAGAGGCATTTGAAATGGCCAAGTAGTTGCAGGAATC GACTGGAAACCGGGGTGGTAAGGTGAAGCCATAGAACATTCCAGGCCCCCTCCCCTAAATGAGATGGAAG GAGTGCCTGTTTTGAACAAGCCAGGGGCATCTGGGGACCGTTAAGGCCTGGGGGTGGTGATGGGGACTGG AGGGTGTGAGGCAACCAGGGGGTGCCCCTCTGAGCCACCACAGACAGAATGGTTCAGAAGGCCAGGCACA CTGGCTCTCGCCTGTAATCCAAGCACTTTGGGAGGCCAAGGAGGGAAGATGGCTTCGGCCAAGGAGGGAA GATGGCTTCAGCCCAGGAGTTCAAGGCCAGCCTGGAAAACATGGCAAAACCTCTGTCTACAAAAAATACA AAAAATTAGCCAGGCATGGTGATGCACGCCTGTCGTCCCAGCTACTCAGGAGGCTTAGATGGGAGGATCA CTTGAGCCGGGGAGTTTGAGGCTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAA CGAGACCCTGTCTTAAAAAAATTTTTTTTGGCCTGGTGCGGTGGCTCACGCCTGTAATGCCAGCACTTTG GGAGTCCAAGGTGGGTGGATCACCTGGAGGTCGGGAGTTTGAGACCAGTCTGACCAACATGGAGAAACCC CATCTCTACTAAAAACACAAAAATTAGCCGGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTCTGGAG GCTGAGGCAGGAGAATCCCTTGAACCCGGGAGGCGGAAGTTGCAGTGAGCCGAGATCGCACCATTGCACT CCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAAAAAACAAAACAAAACAAAAAAAACAACCAAAACAA ACAAACAAAAAACTGTAATTAAAATAATTAAAAGAAAAAAGTTAAAAAAAAAAAAAAGAGAGGATGGCTC AAAGGCTGGAAACAGGGAAGGCCACTGTGAGGGGAGGACAGGCAGGGCTAGACCTCTCTGGAAGGAGGAG GGAGAGGTACCCGTGGGCCCGGCACAGGAGACTCTTAATCTCCTGGCTCCCGGGGGCTTCTGTGGGCCTG TGACTCAGGATTTCTGTGCCTCTGTTGATGAAAAGAAAAATCCTGAAGAAAACACTGTTCCCATAGTAAC ACAGCTCTAATTAGAGACTCCAAGGCCAAGCGAGGGCCTTGGAGCCAGGAGGGGCCCTGCTCTACTGGGG GGACGACACCCCTTTCCCCTATCCCTCCCTGCTGGGGTGTGGCCTGATGTCTACGTGGCACCAGGCCCCT AAATCCTTTCAACATCCTGGCGGAGCGGAGAGGCTGGGCCCTTTTGACAGGTGGGGAAACTGAGGAAGGT TGCAGGGAAGGCACTCATCCAAGGGTGCCTGGCCCCCCGCGGTGGGTGCCTCACTGGCTGGCCTAAACCT TTGCATCAAACCAGTTCCAGGATTGAACGCAACAGGCTGATGGGGACTGAGTCGTGGTACAGATGGCGGC AGTTGTGTGGCCCTGGGCCCAGGAATGGCTGGGAAGCTCCCTTTCTTCTCTGGCTTGGGGGATGAGGTTA GTGTAAATTTCATGGAGTTGCCAGGAGGATTAAGGCCGACGTGCATTCACACGTGGCCCCGTGGCTGCCG CCAGTTAAGCCCTGCGCAGCCATTGGAAGTCTCATTGAGAAGGAGCCTCCCGGCTTCCTGCATTTGTTCC AGGCGGGCTGGTAAGCGCCCTGCTTATTTGCAAGGCTGTGTGAGGACGAGCCCTGTAAACCCTAGGACGA GGCTGTGCTAATGTGGTTTCTGTTCCACTGTCTCCCCTTCTCCTTTTGCCCCTCTTTCTGGGGAACCTGG AGCCCCTGATGCCCTCTGTTTTTTCCTGCTGCTGGGGTGGACCTAGAACCTCTCCCTCCATCCTTTCTGC TGCTGGGGTGGGCCTGCAGGAGGCTGTCCTCTTACCTGGTCCCTAACTTCCCTCCGATCAGCGGGGCTTC AGCGGAGCCCCAGCGCATTGGACAGGTGGTGCTCTGTGGCCGGCACAGGCCAGGGCCCAGGGTGCGGCCC CTGCCTGTAGGTAGACATGCAGGCCCTTCTGAGCAGAATGAGGGGGCGGTGAGGGCAGCTGTGCGGGTGT GGCTGGCCTGACGGCTCCCTGCAGCCCTGCGGCTTCTGTGCAGTGGGGGTGGGGCGGGCCAGACCTTTGC AGGGCCTCTTGGCTGGTGGAGGGCTGAGTGAGCAGAGGCCCCAGCCCTCGTGTTCCCTGGGGTGTGGCCT TAGGATGGTCCCGGCACCCTGGGACCCAGCCCCTGCTCACCTTATCCTCCTCCCGTGCTTGGCTGGGGTG TGGTGGCTGAGCCAGCCCACCCAGTGCGGTGGATGCTCGTCGGAGGGCAGAGGGTGGGCTACCGGCTTAA GGGGCCCCAGGGAACCTGGGGGGTGGAGCCCAAGGGGTTCCAAGAAGGGGCGGGGCCAGGAACCCATAGA CAAGAGGGTGGGGCAGGGAAAGGGCGTGGCAAGAGGGCCACCCACCTCCGGTCCAGAGAGCCAGCCAGAC CCTTACTTTCTCTTGCTGTGTGACCTTAGGCAAGGACATGCCACCACCGGCCTTAGTCTCCCTCTTTGTG AAGTAGGATGAAGATCCCCACCTGTGGAGCAGATGTGGGGCTGCATGGTTGGGTCAGGATGGAACAGGAT GGGGAGGCCGGGCGTGGTGGCTTACCCCTGTAATCCCAGCACTTTGGGAGGCAAAGGTGGGAGGACTGCT TGAGTCCTGGAGTTTGGGCAACATAGCGAGACCACCCCCATCTCTACAAAATAATGTTAAAGTTAGCCAG GTGTAGTGGTGAGTGCCTGTGGTCCCACCTACTGGGGAGACTGAGGCAAGAGGATCCTTTGAGCCCAGGA GGTGGAGGCTGTAGAGAGCCATGCTTGGGCCACTTGCACTCCAGCCTGGGCAACAGAGCAAGACCCTATC TCTAAAAAAAAAATGGAATTGAGGATGTGTCCTCTGGGTGTGGGCTCTACCACCCACCAGCCTCCCTCTC CTGTGGGTGCTGCCTGCCACCCACCGCTGAGGTCCCTGCAGCATCAAGGTGCCCAAACGAAGACACTCTC CAGCTCTGAGCCAGGCACCCATACAGAGCCCGGCAGACGCCTCTGCTGCTGCAGTTCTTAGAATCCAGAG CGCGTGGGGAATGTGAATTTGTGCTGCTGGAGCCAAACATCCCACCTCCAGGTTTTAGCTGGAGGAATCC ATGTGGATATGCAAAGCAATGTAGTTATAATGAATAGCAATTGTGGGCTGGGCGCAGTGGCTCATACCTG TAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCGGCCTGGCC AACATAATGAAACTCCGTCTCTACTAAAAATACAAAAAAATTAGCCGGGCATAGTGGCGGGTGCCTGTAA TCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTTCAGTGAGGCGA GATCGTGCCATTGCACTCCAGCCCGGGAGACACAGCGAGACTCTCTTTCTCAAAAAAAGAATAGCAGCTT TGCTATAGCTTAGGGGAGCAAAACCCGAAAGCCACCTTAAGTTTCCCGAAGATAGAGATCCCTGGGGTCC TATTCTGAGACAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGGATCTCAGCTCACTGCAGCC TCCGCCTCCTGGGTTCAAGCAATTCTCCTGCGTCAGCCTCCCGAGCAGCTGGGATTACAGGCGCCCGGCA CCACCCCCAGCTAATTTTTTTTTTTTTGAGACAGAGTCTCGCATTGTCGCCCAGGCTGGAGTGCAGTGGC GCGATCTTGGCTCACTGCAAGCTCCACCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAG CAGGGACTACAGGCGCCCGCCACCGTGCCCGGCTAATTTTTTTTTTTTGTATTATTAATAGAGACGGGTT TCACCGTGTTAGGATGATCTCGATCTCCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGG ATTACAGGCATGAGCCACCTTGCCTGGTCCTTTTTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATGT TGGCCAGGCTGGTCTCAAACTCCTGACCTCATGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTAC AGGTGTGGGCCACTGTGCCCGGCCAGTCCCATTCTACTTTTTAGGGACATGGAATCATGTAAAGATGCCA TACAGAAAACAGTATGCAAATCCAGAGACAGAGGACATCTGTGCATGTTTCTTTCTTTCTTCCTTTTTTT TTTTTTTTTTTTTTTTGAGATGGATTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCAATCTCAGC TCACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGACTTCCAAGTAGCTGGGATTACA GGCATGCCCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGGCGGGGTTTCACCATGTTGGCAAGG CTGGTCTTGAACTCATGACCTCAGGTGATCCACCCGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGCGT GAGCCGCCGTGGCAACCCGCATGCTTCTTATGTATAAGAAAAAAACAGCTAGAAAGTTGTGGGTTCACTG GCTGGGCACATGGTGGCTTGTGTCTGTAACCTCAGCACTTTGGGAGGCTGAGTTAGGAGGATCATGTGAG GCCGGGAGTTCAAGACCATCCTAGGCAACATAGCCAGACCCTGTCTGTACCAAATAGAAAAAAAAATTAA CTTGATGTGGTGGTGTGTGCCTGTAGTCTCAGCTATTTGGGAGGCTGAGGTGGGAGGATCACTTGAGCCC AGGAAGTCGAGGCTACAGTGAGCTATGATTGTGCCACTGCACTCCAACCTGGGCAACAGAGCAAGACCCT GAATCAAAAAGAAAGAGATGTATTTGCCAACACAGGGGTGTTCTGCAGTGGGGTGGGAAGGGGACGTGTA GGACTTCATAGTTTCCTTTTTTTTGTTTTAGAGACAGGGCTTAAAAAAAAATTTTTTTTTTTTTTTTGAG GCGGAATTTCATTCTTGTTGCCCAGGCTGGAGTGATCTCGGCTCACTGCCATCTCCGCCTCCCAGGTTGA AGTGATTCTCCTGCCTCAGCCTCAGGCAATTTTGTATTTTTAGTAGAGACGGGGTGACTCCATGTTGGTC AGGCTGGTCTCAAACTCCCGACCTCGGGTGATCTGCCTGCCTTGGCCTCCCAAACTGCTGGGATTACAGG TGTGAGCCACTGTGCCTGGCCCCTTTTTTTTTTTTTTAAGTAGGGTCTTGCTAAGTTGTCCAGGCTGGTC TTGAACTCCTGGTCTCAAATGATCCTCCTGACTTGGCCTCCCAAAAGGCTGGGATTGCAGGAGATATGAG CCACCGCACCCGGCCCTTTTATAAGTTTTCTAAAGGAAAGGAACATGTACCATCGTGTTTTATTTTAATT TTTACATAGAAGCAGGAACAATAGCATGAACCCCCAGACACGGCCCCCCAAGATGCGCTGTTCCGCTGTG CTGCAGCCCCATTTGTCCTTTTCTATACCATTTTTGGTTGTATTTGAAGCAAATCCCTGACATCAGGGCA TTTCATCCCAAAATACTTCCATCTGTGTTTCTAAAAAAACGAGGCCATTTTCTTATGTAACCACAACGTG ATCAACAGTAATCAATGCTTAACATCTAATTCTGGGCCACGTTAAGACCCTCCTGATTGGCTCAAGAATG TCTTTTGTGCAGTTGGTTTCTTGATTCTTTTTGTTTTTTTTGAGACAGGGTCTCACTGTGTCACCCAGGC TGGAGTGCAGTGGTGCAATCACGGCTCACTGCAGCCTCAGCCTCCTGCCTCAGCGATCCTCCTGCCTCAG CCTCCCAAGTAGCTGGGACCACAGGTTTGCACCACCACTCCCAGCTAATTAAAAAAAGTAATTTGTAGAG ACGGGGGTGGGGTGGGGGTCTTGCTATGTTGCCCAGGCTGGTCTCAAACTCCTAGACTCAAACAATCCTC CTGCCTTGGCCTCCCAAAGTGTTGCGATCACAGGCATGAGCCCCTGTCCCTGGCCCCTATTATTTCTCTA ACTGGGGAAAGTCATGTGGGAACAGATGTAGCTTGCCTTGGCCTCTGACCGGCCCTGCCTGCGTTCCTGG GTGCTCTCTGCTGCTTCTCATGTGTGCCACTGTGGGGACTCGGCCGCCCACCCCACCCCGTGGTGTTACC TTGCGTGTGTAGTTCTGTGAGCTCAGGGCTATGGTCTGCCAGAACTAGGGGGCGTGGGGCCCCAGTACCA GCCCAAGGCCTCCTCTCTGCAGGTATGGACCTGTCTGCCAATCAGGACGAGGAGACCGACCAGGAGACCT TCCAGCTGGAGATCGACCGCGACACCAAAAAGTGTGCCTTCCGTACCCACACGGGCAAGTACTGGACGCT GACGGCCACCGGGGGCGTGCAGTCCACCGCCTCCAGCAAGTGAGTGCCTCGCTCCCACCTGTCACCGCCC CCACCACCTTGCCTGGGCTACCCCGCCTGACCCTGTCCCGCCATCCCCCAGGAATGCCAGCTGCTACTTT GACATCGAGTGGCGTGACCGGCGCATCACACTGAGGGCGTCCAATGGCAAGTTTGTGACCTCCAAGAAGA ATGGGCAGCTGGCCGCCTCGGTGGAGACAGCAGGTAACACTAAAGCCCCAGTTCCCTGGAGCCGTCCTGG AGTCCTGGAGGGTCTGGCCATGCCGTGGTCACTTGGTAGCCCCAGCCAAGGCCTGCTCTGTGCTGGGCAT CCCCCCGGACTGGCCCCGCACTGTCCTACCCTGGGGACTGCTGTGTGACCCCAGCTCCTGGCCCTCCCTC TCTGGTCACCCCAGCCTCCACCCCACTCCCTGCCAGGAGGCTCACTGACTCCCCTCTTTCTGGGACAGGG GACTCAGAGCTCTTCCTCATGAAGCTCATCAACCGCCCCATCATCGTGTTCCGCGGGGAGCATGGCTTCA TCGGCTGCCGCAAGGTCACGGGCACCCTGGACGCCAACCGCTCCAGCTATGACGTCTTCCAGCTGGAGTT CAACGATGGCGCCTACAACATCAAAGGCAGGTTCTCCTGTGGGCAGCTGCTGGGCAGGGAACCCCTCGGT CGGGGCTGGGGTCAGTGCTGCGGGGAGCGCCCTCTGCATCCACACTGGACCCTGGCTTGGCTCAGGGCCA TTCCAGGCCCTAAAGGGACAGGTGTCTGATGGCCACCAGGGGCTCTGGGATGCAAGCAGCCCCTTTCCCT CTTGTCTGTGTGGTTGGGGGGACTTACCTTGCCCACCTGACAGAGAGGTGTGTGGAGGGGAGAGCAGGGA GGGGAAGGAGAGCAGGGAAGGGGAGGGAGGAGAGCAGGGGAGGGGAGAGCCGGGAAGGAGAGGAGAGCAG GGGTGGGGAGGTTCTGGAAAGGGTGTGCAGGGGAGGACGCGCCTCGGTTATGGGACTGGAGCCCCTTCCC AGGAGGACCCCCAACAATCCAGAGGTGCCTGTTAGGATTCAGAACATGGTTTTTTTGTTTGTTTTTTTGA GACTCACTCCCTCACCCTGGCTGGACTGCAGTGGCGTTATCTCGGCTCACTGCAACCTCTGCCTCCTGGG TTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACCACCACGCCTGGCTA ATTTTTATATTTTTAAAATTTATTATTTATTTATTTTGAGACCCAGTCTGGAGTGCAGTGGCGTTATCTC GGCTCTCTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACT ATGTGTGGGAGCCACCATGCCTGGCTAATTTTTTTGTATTTTTCATAGAGACGGGTTTCACCATGTTGTC CAGGCTGGTCTTGAATTCGTGGCCTCAAGTGATCCGCCCACCTCAGCCTCCCACAGTGCTGGGTTTATAG GTGTGAGCCACCACACCCGGCTAATTGTTTTGTATTTTTAGTAGAGACGGAGCTTCACTATGTTGGCAAG GCTGGCTCGAACTCCTGACCTCAAGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGT GAGCCACTGCGGCCGAGCAGAACACGTTCTAGGACCCTTGTTCATGTGTCCATCATGGACAGGAGGACGT GCGGGCCATAGGGACCCTGGCTCATTCCGGAGCCGGGACTGGAGGGTGGGGCGTCACCCTTGGGAACACC CGTGCCCACCCTCCGCTGCCCAGGGTAGGGGTGGGGAGCCAGGCTTTGGGCCCCACTTGATAAAGTCCCC TCCCCAGACTCCACAGGCAAATACTGGACGGTGGGCAGTGACTCCGCGGTCACCAGCAGCGGCGACACTC CTGTGGACTTCTTCTTCGAGTTCTGCGACTATAACAAGGTGGCCATCAAGGTGGGCGGGCGCTACCTGAA GGGCGACCACGCAGGCGTCCTGAAGGCCTCGGCGGAAACCGTGGACCCCGCCTCGCTCTGGGAGTACTAG GGCCGGCCCGTCCTTCCCCGCCCCTGCCCACATGGCGGCTCCTGCCAACCCTCCCTGCTAACCCCTTCTC CGCCAGGTGGGCTCCAGGGCGGGAGGCAAGCCCCCTTGCCTTTCAAACTGGAAACCCCAGAGAAAACGGT GCCCCCACCTGTCGCCCCTATGGACTCCCCACTCTCCCCTCCGCCCGGGTTCCCTACTCCCCTCGGGTCA GCGGCTGCGGCCTGGCCCTGGGAGGGATTTCAGATGCCCCTGCCCTCTTGTCTGCCACGGGGCGAGTCTG GCACCTCTTTCTTCTGACCTCAGACGGCTCTGAGCCTTATTTCTCTGGAAGCGGCTAAGGGACGGTTGGG GGCTGGGAGCCCTGGGCGTGTAGTGTAACTGGAATCTTTTGCCTCTCCCAGCCACCTCCTCCCAGCCCCC CAGGAGAGCTGGGCACATGTCCCAAGCCTGTCAGTGGCCCTCCCTGGTGCACTGTCCCCGAAACCCCTGC TTGGGAAGGGAAGCTGTCGGGTGGGCTAGGACTGACCCTTGTGGTGTTTTTTTGGGTGGTGGCTGGAAAC AGCCCCTCTCCCACGTGGCAGAGGCTCAGCCTGGCTCCCTTCCCTGGAGCGGCAGGGCGTGACGGCCACA GGGTCTGCCCGCTGCACGTTCTGCCAAGGTGGTGGTGGCGGGCGGGTAGGGGTGTGGGGGCCGTCTTCCT CCTGTCTCTTTCCTTTCACCCTAGCCTGACTGGAAGCAGAAAATGACCAAATCAGTATTTTTTTTAATGA AATATTATTGCTGGAGGCGTCCCAGGCAAGCCTGGCTGTAGTAGCGAGTGATCTGGCGGGGGGCGTCTCA GCACCCTCCCCAGGGGGTGCATCTCAGCCCCCTCTTTCCGTCCTTCCCGTCCAGCCCCAGCCCTGGGCCT GGGCTGCCGACACCTGGGCCAGAGCCCCTGCTGTGATTGGTGCTCCCTGGGCCTCCCGGGTGGATGAAGC CAGGCGTCGCCCCCTCCGGGAGCCCTGGGGTGAGCCGCCGGGGCCCCCCTGCTGCCAGCCTCCCCCGTCC CCAACATGCATCTCACTCTGGGTGTCTTGGTCTTTTATTTTTTGTAAGTGTCATTTGTATAACTCTAAAC GCCCATGATAGTAGCTTCAAACTGGAAATAGCGAAATAAAATAACTCAGTCTGCAGCCCCAG Download Select all
Length	13852
OMIM ID	602689
HGNC ID	HGNC:11148
Unigene ID	Hs.118400
Ensembl ID	ENSG00000075618
PharmGKB ID	-

mRNA Information

mRNA ID	NM_003088.3
Exon	join(1..964,10453..10609,10692..10813,11059..11226, 12468..13852)
mRNA Sequence	>6624 AGCTGGGCTTTGTGGAGCGCTGCGGAGGGTGCGTGCGGGCCGCGGCAGCCGAACAAAGGAGCAG GGGCGCCGCCGCAGGGACCCGCCACCCACCTCCCGGGGCCGCGCAGCGGCCTCTCGTCTACTGC CACCATGACCGCCAACGGCACAGCCGAGGCGGTGCAGATCCAGTTCGGCCTCATCAACTGCGGC AACAAGTACCTGACGGCCGAGGCGTTCGGGTTCAAGGTGAACGCGTCCGCCAGCAGCCTGAAGA AGAAGCAGATCTGGACGCTGGAGCAGCCCCCTGACGAGGCGGGCAGCGCGGCCGTGTGCCTGCG CAGCCACCTGGGCCGCTACCTGGCGGCGGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTG CCCGGTCCCGACTGCCGTTTCCTCATCGTGGCGCACGACGACGGTCGCTGGTCGCTGCAGTCCG AGGCGCACCGGCGCTACTTCGGCGGCACCGAGGACCGCCTGTCCTGCTTCGCGCAGACGGTGTC CCCCGCCGAGAAGTGGAGCGTGCACATCGCCATGCACCCTCAGGTCAACATCTACAGCGTCACC CGTAAGCGCTACGCGCACCTGAGCGCGCGGCCGGCCGACGAGATCGCCGTGGACCGCGACGTGC CCTGGGGCGTCGACTCGCTCATCACCCTCGCCTTCCAGGACCAGCGCTACAGCGTGCAGACCGC CGACCACCGCTTCCTGCGCCACGACGGGCGCCTGGTGGCGCGCCCCGAGCCGGCCACTGGCTAC ACGCTGGAGTTCCGCTCCGGCAAGGTGGCCTTCCGCGACTGCGAGGGCCGTTACCTGGCGCCGT CGGGGCCCAGCGGCACGCTCAAGGCGGGCAAGGCCACCAAGGTGGGCAAGGACGAGCTCTTTGC TCTGGAGCAGAGCTGCGCCCAGGTCGTGCTGCAGGCGGCCAACGAGAGGAACGTGTCCACGCGC CAGGGTATGGACCTGTCTGCCAATCAGGACGAGGAGACCGACCAGGAGACCTTCCAGCTGGAGA TCGACCGCGACACCAAAAAGTGTGCCTTCCGTACCCACACGGGCAAGTACTGGACGCTGACGGC CACCGGGGGCGTGCAGTCCACCGCCTCCAGCAAGAATGCCAGCTGCTACTTTGACATCGAGTGG CGTGACCGGCGCATCACACTGAGGGCGTCCAATGGCAAGTTTGTGACCTCCAAGAAGAATGGGC AGCTGGCCGCCTCGGTGGAGACAGCAGGGGACTCAGAGCTCTTCCTCATGAAGCTCATCAACCG CCCCATCATCGTGTTCCGCGGGGAGCATGGCTTCATCGGCTGCCGCAAGGTCACGGGCACCCTG GACGCCAACCGCTCCAGCTATGACGTCTTCCAGCTGGAGTTCAACGATGGCGCCTACAACATCA AAGACTCCACAGGCAAATACTGGACGGTGGGCAGTGACTCCGCGGTCACCAGCAGCGGCGACAC TCCTGTGGACTTCTTCTTCGAGTTCTGCGACTATAACAAGGTGGCCATCAAGGTGGGCGGGCGC TACCTGAAGGGCGACCACGCAGGCGTCCTGAAGGCCTCGGCGGAAACCGTGGACCCCGCCTCGC TCTGGGAGTACTAGGGCCGGCCCGTCCTTCCCCGCCCCTGCCCACATGGCGGCTCCTGCCAACC CTCCCTGCTAACCCCTTCTCCGCCAGGTGGGCTCCAGGGCGGGAGGCAAGCCCCCTTGCCTTTC AAACTGGAAACCCCAGAGAAAACGGTGCCCCCACCTGTCGCCCCTATGGACTCCCCACTCTCCC CTCCGCCCGGGTTCCCTACTCCCCTCGGGTCAGCGGCTGCGGCCTGGCCCTGGGAGGGATTTCA GATGCCCCTGCCCTCTTGTCTGCCACGGGGCGAGTCTGGCACCTCTTTCTTCTGACCTCAGACG GCTCTGAGCCTTATTTCTCTGGAAGCGGCTAAGGGACGGTTGGGGGCTGGGAGCCCTGGGCGTG TAGTGTAACTGGAATCTTTTGCCTCTCCCAGCCACCTCCTCCCAGCCCCCCAGGAGAGCTGGGC ACATGTCCCAAGCCTGTCAGTGGCCCTCCCTGGTGCACTGTCCCCGAAACCCCTGCTTGGGAAG GGAAGCTGTCGGGTGGGCTAGGACTGACCCTTGTGGTGTTTTTTTGGGTGGTGGCTGGAAACAG CCCCTCTCCCACGTGGCAGAGGCTCAGCCTGGCTCCCTTCCCTGGAGCGGCAGGGCGTGACGGC CACAGGGTCTGCCCGCTGCACGTTCTGCCAAGGTGGTGGTGGCGGGCGGGTAGGGGTGTGGGGG CCGTCTTCCTCCTGTCTCTTTCCTTTCACCCTAGCCTGACTGGAAGCAGAAAATGACCAAATCA GTATTTTTTTTAATGAAATATTATTGCTGGAGGCGTCCCAGGCAAGCCTGGCTGTAGTAGCGAG TGATCTGGCGGGGGGCGTCTCAGCACCCTCCCCAGGGGGTGCATCTCAGCCCCCTCTTTCCGTC CTTCCCGTCCAGCCCCAGCCCTGGGCCTGGGCTGCCGACACCTGGGCCAGAGCCCCTGCTGTGA TTGGTGCTCCCTGGGCCTCCCGGGTGGATGAAGCCAGGCGTCGCCCCCTCCGGGAGCCCTGGGG TGAGCCGCCGGGGCCCCCCTGCTGCCAGCCTCCCCCGTCCCCAACATGCATCTCACTCTGGGTG TCTTGGTCTTTTATTTTTTGTAAGTGTCATTTGTATAACTCTAAACGCCCATGATAGTAGCTTC AAACTGGAAATAGCGAAATAAAATAACTCAGTCTGCAGCCCCAGAAAAAAAAAAAAAAAA Download Select all
Length	2812

CDS Information

Location	join(133..964,10453..10609,10692..10813,11059..11226, 12468..12670)
CDS Sequence	>lcl\|NM_003088.3_cds_NP_003079.1_1 [gene=FSCN1] [protein=fascin] [protein_id=NP_003079.1] [location=133..1614] ATGACCGCCAACGGCACAGCCGAGGCGGTGCAGATCCAGTTCGGCCTCATCAACTGCGGCAACAAGTACC TGACGGCCGAGGCGTTCGGGTTCAAGGTGAACGCGTCCGCCAGCAGCCTGAAGAAGAAGCAGATCTGGAC GCTGGAGCAGCCCCCTGACGAGGCGGGCAGCGCGGCCGTGTGCCTGCGCAGCCACCTGGGCCGCTACCTG GCGGCGGACAAGGACGGCAACGTGACCTGCGAGCGCGAGGTGCCCGGTCCCGACTGCCGTTTCCTCATCG TGGCGCACGACGACGGTCGCTGGTCGCTGCAGTCCGAGGCGCACCGGCGCTACTTCGGCGGCACCGAGGA CCGCCTGTCCTGCTTCGCGCAGACGGTGTCCCCCGCCGAGAAGTGGAGCGTGCACATCGCCATGCACCCT CAGGTCAACATCTACAGCGTCACCCGTAAGCGCTACGCGCACCTGAGCGCGCGGCCGGCCGACGAGATCG CCGTGGACCGCGACGTGCCCTGGGGCGTCGACTCGCTCATCACCCTCGCCTTCCAGGACCAGCGCTACAG CGTGCAGACCGCCGACCACCGCTTCCTGCGCCACGACGGGCGCCTGGTGGCGCGCCCCGAGCCGGCCACT GGCTACACGCTGGAGTTCCGCTCCGGCAAGGTGGCCTTCCGCGACTGCGAGGGCCGTTACCTGGCGCCGT CGGGGCCCAGCGGCACGCTCAAGGCGGGCAAGGCCACCAAGGTGGGCAAGGACGAGCTCTTTGCTCTGGA GCAGAGCTGCGCCCAGGTCGTGCTGCAGGCGGCCAACGAGAGGAACGTGTCCACGCGCCAGGGTATGGAC CTGTCTGCCAATCAGGACGAGGAGACCGACCAGGAGACCTTCCAGCTGGAGATCGACCGCGACACCAAAA AGTGTGCCTTCCGTACCCACACGGGCAAGTACTGGACGCTGACGGCCACCGGGGGCGTGCAGTCCACCGC CTCCAGCAAGAATGCCAGCTGCTACTTTGACATCGAGTGGCGTGACCGGCGCATCACACTGAGGGCGTCC AATGGCAAGTTTGTGACCTCCAAGAAGAATGGGCAGCTGGCCGCCTCGGTGGAGACAGCAGGGGACTCAG AGCTCTTCCTCATGAAGCTCATCAACCGCCCCATCATCGTGTTCCGCGGGGAGCATGGCTTCATCGGCTG CCGCAAGGTCACGGGCACCCTGGACGCCAACCGCTCCAGCTATGACGTCTTCCAGCTGGAGTTCAACGAT GGCGCCTACAACATCAAAGACTCCACAGGCAAATACTGGACGGTGGGCAGTGACTCCGCGGTCACCAGCA GCGGCGACACTCCTGTGGACTTCTTCTTCGAGTTCTGCGACTATAACAAGGTGGCCATCAAGGTGGGCGG GCGCTACCTGAAGGGCGACCACGCAGGCGTCCTGAAGGCCTCGGCGGAAACCGTGGACCCCGCCTCGCTC TGGGAGTACTAG Download Select all
CCDS ID	CCDS5342.1

Protein Information

Protein ID	NP_003079.1
Protein Name	fascin actin-bundling protein 1
Molecular Wt. (Da)	54399
Protein Sequence	>6624 MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRS HLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQTVSP AEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQRYSVQTAD HRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFAL EQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTAT GGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKNGQLAASVETAGDSELFLMKLINRP IIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFNDGAYNIKDSTGKYWTVGSDSAVTSSGDTP VDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKASAETVDPASLWEY Download Select all
Length	493
Uniprot ID	O75874
Ensembl Protein ID	ENSP00000260985

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	39
S	Phosphorylation	38
K	Acetylation	471

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
58	ACTA1	30	NP_001091.1	in vitro	8999969
70	ACTC1	15	NP_005150.1	in vivo	12139639
1499	CTNNB1	286	NP_001895.1	in vitro	10026156
4804	NGFR	1197	NP_002498.1	in vitro;in vivo;yeast 2-hybrid	12789270
5578	PRKCA	1498	NP_002728.1	in vitro;in vivo	14532112

Pathway Information

Pathway Name	Pathway ID
MicroRNAs in cancer	hsa05206

Structure Information

PDB ID	1DFC
Resolution	2.9
Method	X-RAY DIFFRACTION
Chains	A,B
Molecule	FASCIN
Model	View

Domain Information

ID	Location	Description
cd00257	13-134	Fascin
cl22458	13-134	RICIN superfamily
cd00257	260-378	Fascin
cl22458	260-378	RICIN superfamily
cd00257	383-493	Fascin
cl22458	383-493	RICIN superfamily
cd00257	139-256	Fascin
cl22458	139-256	RICIN superfamily
pfam06268	268-378	Fascin
pfam06268	21-134	Fascin
pfam06268	391-493	Fascin
pfam06268	142-256	Fascin
pfam06229	301-376	FRG1

Ontology Information

HPRD ID	126
Molecular Class	Structural protein
Molecular Function	Transmembrane receptor activity (GO:0004888)
Biological Process	Immune response (GO:0006955)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO