Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| FZD5 | 7855 | frizzled class receptor 5 | 2 | HFZ5, DKFZP434E2135 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24811787 | 2014 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 12 Stage : - | Methylation specific microarray | Methylation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | GPCR / Class F : Frizzled receptors |
| Description | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008] | Chromosome | 2 |
| Location | 2q33.3 |
| Start | 208627310 |
| End | 208634143 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 6834 |
| OMIM ID | 601723 |
| HGNC ID | HGNC:4043 |
| Unigene ID | Hs.17631 |
| Ensembl ID | ENSG00000163251 |
| PharmGKB ID | PA28460 |
mRNA Information
| mRNA ID | ?NM_003468.3 |
|---|---|
| Exon | join(1..155,426..6834) | mRNA Sequence | Download Select all |
| Length | 6584 |
Protein Information
| Protein ID | NP_003459.2 |
|---|---|
| Protein Name | frizzled class receptor 5 |
| Molecular Wt. (Da) | 128172 |
| Protein Sequence | Download Select all |
| Length | 585 |
| Uniprot ID | Q86X55 |
| Ensembl Protein ID | ENSP00000325690 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 4040 | LRP6 | 4617 | NP_002327.2 | in vivo | 12857724 |
| 4920 | ROR2 | 3822 | NP_004551.2 | in vivo | 12839624 |
| 7474 | WNT5A | 1293 | NP_003383.2 | in vivo | 9054360 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Basal cell carcinoma | hsa05217 |
| Hippo signaling pathway | hsa04390 |
| HTLV-I infection | hsa05166 |
| Melanogenesis | hsa04916 |
| Pathways in cancer | hsa05200 |
| Proteoglycans in cancer | hsa05205 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| Wnt signaling pathway | hsa04310 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd07460 | 29-156 | CRD_FZ5 |
| cl02447 | 29-156 | CRD_FZ superfamily |
| pfam01534 | 225-540 | Frizzled |
| cl21587 | 225-540 | 7tm_2 superfamily |
| cd07456 | 32-152 | CRD_FZ5_like |
| cd07461 | 29-154 | CRD_FZ8 |
| cd07458 | 33-152 | CRD_FZ1_like |
| pfam01392 | 33-148 | Fz |
| smart00063 | 33-150 | FRI |
| cd07457 | 33-148 | CRD_FZ9_like |
| cd07464 | 33-157 | CRD_FZ2 |
| cd07463 | 29-149 | CRD_FZ9 |
| cd07466 | 33-154 | CRD_FZ7 |
| cd07066 | 32-137 | CRD_FZ |
| cd07465 | 33-157 | CRD_FZ1 |
| cd07462 | 33-149 | CRD_FZ10 |
| cd07448 | 33-149 | CRD_FZ4 |
| cd07442 | 30-141 | CRD_SFRP4 |
| cd07441 | 30-141 | CRD_SFRP3 |
| cd07449 | 33-137 | CRD_FZ3 |
| cd07446 | 33-137 | CRD_SFRP2 |
| cd07444 | 28-138 | CRD_SFRP5 |
| cd07450 | 33-137 | CRD_FZ6 |
| cd07453 | 37-138 | CRD_crescent |
| cd07888 | 33-142 | CRD_corin_2 |
| cd07443 | 28-137 | CRD_SFRP1 |
| cd07454 | 33-137 | CRD_LIN_17 |
| cd07452 | 40-137 | CRD_sizzled |
| cd07447 | 31-135 | CRD_Carboxypeptidase_Z |
| cd07455 | 37-137 | CRD_Collagen_XVIII |
| cd07445 | 33-133 | CRD_corin_1 |
Ontology Information
| HPRD ID | 9282 |
|---|---|
| Molecular Class | G protein coupled receptor |
| Molecular Function | Transporter activity (GO:0005215) |
| Biological Process | Transport (GO:0006810) |
Drug Information
No matching records could be found.