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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21636702 | 2011 | Cell line : - Source : Johns Hopkins University (Baltimore, Maryland, U.S.A.). Sample Type : - No. of Sample : 17 primary CRCs relative to 8 non-neoplastic colonic mucosae Stage : Duke Stage A-D. | Methylation microarray-based scanning,Real-time quantitative methylation-specific PCR (qMSP) assays. | Methylation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | GPCR / Class B : Glucagon receptors |
| Description | - | Chromosome | 6 |
| Location | 6p21 |
| Start | 39016557 |
| End | 39056657 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 40101 |
| OMIM ID | 138032 |
| HGNC ID | HGNC:4324 |
| Unigene ID | Hs.389103 |
| Ensembl ID | ENSG00000112164 |
| PharmGKB ID | PA28725 |
mRNA Information
| mRNA ID | NM_002062.3 |
|---|---|
| Exon | join(1..138,7617..7713,8692..8799,16931..17049, 17417..17523,24082..24235,24830..24989,29542..29602, 30177..30246,30332..30420,30784..30922,31918..31959, 37126..38964) | mRNA Sequence | Download Select all |
| Length | 3123 |
Protein Information
| Protein ID | NP_002053.3 |
|---|---|
| Protein Name | |
| Molecular Wt. (Da) | 463 |
| Protein Sequence | Download Select all |
| Length | 0 |
| Uniprot ID | P62701 |
| Ensembl Protein ID | ENSP00000362744 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 2641 | GCG | 676 | NP_002045.1 | in vitro;in vivo | 11116211 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| cAMP signaling pathway | hsa04024 |
| Insulin secretion | hsa04911 |
| Neuroactive ligand-receptor interaction | hsa04080 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00002 | 144-398 | 7tm_2 |
| cl21587 | 144-398 | 7tm_2 superfamily |
| pfam02793 | 60-128 | HRM |
| cl02422 | 60-128 | HRM superfamily |
| smart00008 | 58-135 | HormR |
Ontology Information
| HPRD ID | 3402 |
|---|---|
| Molecular Class | G protein coupled receptor |
| Molecular Function | Protein serine/threonine kinase activity (GO:0004674) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
| Uniprot ID | DrugBank ID | Name | Type |
|---|---|---|---|
| P43220 | DB00040 | Glucagon recombinant | BiotechDrug |
| P43220 | DB01276 | Exenatide | BiotechDrug |
| P43220 | DB06655 | Liraglutide | BiotechDrug |
| P43220 | DB09043 | Albiglutide | BiotechDrug |
| P43220 | DB09045 | Dulaglutide | BiotechDrug |