Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| GNA12 | 2768 | guanine nucleotide binding protein (G protein) alpha 12 | 7 | gep |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19098285 | 2009 | Cell line : - Source : Tissue repository at the Case Comprehensive Cancer Center Sample Type : CRC Tumor and adjacent normal tissue No. of Sample : - Stage : - | 2D Gel Electrophoresis,Mass Spectrometry | Unknown | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 7 |
| Location | 7p22.3 |
| Start | 2767739 |
| End | 2883963 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 116225 |
| OMIM ID | 604394 |
| HGNC ID | HGNC:4380 |
| Unigene ID | Hs.487341 |
| Ensembl ID | ENSG00000146535 |
| PharmGKB ID | PA28765 |
mRNA Information
| mRNA ID | XM_011515151.1 |
|---|---|
| Exon | complement(<104978..105945) | mRNA Sequence | Download Select all |
| Length | 2114 |
Protein Information
| Protein ID | XP_011513453.1 |
|---|---|
| Protein Name | 33486 |
| Molecular Wt. (Da) | 308 |
| Protein Sequence | Download Select all |
| Length | 0 |
| Uniprot ID | Q15349 |
| Ensembl Protein ID | ENSP00000265678 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| C | Palmitoylation | 11 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 60 | ACTB | 32 | NP_001092.1 | in vivo | 10787407 |
| 695 | BTK | 2248 | NP_000052.1 | in vitro;in vivo | 9796816 |
| 999 | CDH1 | 1885 | BAA88957.1 | in vitro;yeast 2-hybrid | 11136230 |
| 1000 | CDH2 | 226 | NP_001783.2 | in vitro;yeast 2-hybrid | 11136230 |
| 1013 | CDH15 | 225 | NP_004924.1 | in vitro;yeast 2-hybrid | 11136230 |
| 1816 | DRD5 | 542 | NP_000789.1 | in vivo | 12623966 |
| 2149 | F2R | 1763 | NP_001983.2 | in vivo | 8290554 |
| 2782 | GNB1 | 766 | NP_002065.1 | in vitro | 7829508 |
| 3320 | HSP90AA1 | 777 | NP_001017963.2 | in vitro;in vivo;yeast 2-hybrid | 1 211 799 911 598 130 |
| 5518 | PPP2R1A | 16184 | NP_055040.2 | in vitro;in vivo;yeast 2-hybrid | 15525651 |
| 5536 | PPP5C | 2805 | NP_006238.1 | in vitro;in vivo;yeast 2-hybrid | 12176367 |
| 5578 | PRKCA | 1498 | NP_002728.1 | in vitro;in vivo | 8647866 |
| 5922 | RASA2 | 3351 | BAA11621.1 | in vitro;in vivo | 9796816 |
| 6915 | TBXA2R | 1768 | NP_963998.2 | in vivo | 8290554 |
| 7006 | TEC | 2786 | NP_003206.2 | in vivo | 12515866 |
| 7253 | TSHR | 4537 | NP_000360.2 | in vitro | 8552586 |
| 8698 | S1PR4 | 4779 | NP_003766.1 | in vitro | 12761884 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| cGMP-PKG signaling pathway | hsa04022 |
| Long-term depression | hsa04730 |
| MAPK signaling pathway | hsa04010 |
| Pathways in cancer | hsa05200 |
| Phospholipase D signaling pathway | hsa04072 |
| Regulation of actin cytoskeleton | hsa04810 |
| Sphingolipid signaling pathway | hsa04071 |
| Vascular smooth muscle contraction | hsa04270 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00066 | 58-375 | G-alpha |
| cl21455 | 58-375 | P-loop_NTPase superfamily |
| cd00878 | 208-313 | Arf_Arl |
| cd04156 | 219-300 | ARLTS1 |
| cd04160 | 227-308 | Arfrp1 |
| cd04149 | 219-300 | Arf6 |
| cd00879 | 216-300 | Sar1 |
| pfam00025 | 208-300 | Arf |
| cd04155 | 214-301 | Arl3 |
| cd04153 | 216-313 | Arl5_Arl8 |
| smart00177 | 219-300 | ARF |
| cd04150 | 219-300 | Arf1_5_like |
| cd04157 | 183-300 | Arl6 |
| PLN00223 | 219-300 | PLN00223 |
| PTZ00133 | 219-300 | PTZ00133 |
| cd00882 | 208-306 | Ras_like_GTPase |
| cd04154 | 216-300 | Arl2 |
| smart00275 | 42-379 | G_alpha |
| pfam00503 | 56-370 | G-alpha |
| TIGR00231 | 219-307 | small_GTP |
| smart00178 | 183-299 | SAR |
Ontology Information
| HPRD ID | 10202 |
|---|---|
| Molecular Class | G protein |
| Molecular Function | Protein serine/threonine kinase activity (GO:0004674) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.