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General Information
- Evidence
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20085586 | 2010 | Cell line : - Source : Asan Medical Center (Seoul, Korea). Sample Type : CRC tumor and normal tissue No. of Sample : 104 Stage : - | Chemosensitivity assay,Affymetrix genome-wide human SNP array,Genotyping assay, | Polymorhpism | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Proteoglycans / Cell Surface : Glypicans |
| Description | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008] | Chromosome | 13 |
| Location | 13q32 |
| Start | 92050935 |
| End | 93519490 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 1468556 |
| OMIM ID | 602446 |
| HGNC ID | HGNC:4453 |
| Unigene ID | Hs.655675 |
| Ensembl ID | ENSG00000179399 |
| PharmGKB ID | PA28834 |
mRNA Information
| mRNA ID | NM_004466.5 |
|---|---|
| Exon | join(1..591,50143..50304,294569..295263,329914..330047, 357677..357802,509319..509439,746212..746371, 1467664..1468619) | mRNA Sequence | Download Select all |
| Length | 2966 |
Protein Information
| Protein ID | NP_004457.1 |
|---|---|
| Protein Name | glypican 5 |
| Molecular Wt. (Da) | 61120 |
| Protein Sequence | Download Select all |
| Length | 572 |
| Uniprot ID | P26022 |
| Ensembl Protein ID | ENSP00000295927 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam01153 | 11-572 | Glypican |
| cl12245 | 11-572 | Glypican superfamily |
Ontology Information
| HPRD ID | 3279 |
|---|---|
| Molecular Class | Cell surface receptor |
| Molecular Function | Signal transducer activity (GO:0004871) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.