Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| GTF2H4 | 2968 | General transcription factor IIH, polypeptide 4, 52kDa | 6 | P52; TFB2; TFIIH |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22968445 | 2012 | Cell line : - Source : Department of Pathology of Wrocaw Medical University. Sample Type : - No. of Sample : - Stage : - | Laser capture microdissection,FFPE-FASP,SAX fractionation, LC-MSMS,Label-freequantitation. | Up-regulation | 2.4 | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | General transcription factors, General transcription factor IIH complex subunits |
| Description | - | Chromosome | 6 |
| Location | 6p21.3 |
| Start | 30908200 |
| End | 30914103 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 5904 |
| OMIM ID | 601760 |
| HGNC ID | HGNC:4658 |
| Unigene ID | Hs.485070 |
| Ensembl ID | ENSG00000213780 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_001517.4 |
|---|---|
| Exon | join(1..204,835..974,1236..1340,1733..1864,2466..2562, 2654..2742,2959..3070,3232..3300,3485..3568,3815..3947, 4129..4259,4911..4958,5110..5188,5612..5904) | mRNA Sequence | Download Select all |
| Length | 1736 |
CDS Information
| Location | join(838..974,1236..1340,1733..1864,2466..2562,2654..2742, 2959..3070,3232..3300,3485..3568,3815..3947,4129..4259, 4911..4958,5110..5188,5612..5784) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS34386.1 |
Protein Information
| Protein ID | NP_001508.1 |
|---|---|
| Protein Name | General transcription factor IIH, polypeptide 4, 52kDa |
| Molecular Wt. (Da) | 52055 |
| Protein Sequence | Download Select all |
| Length | 462 |
| Uniprot ID | P62324 |
| Ensembl Protein ID | ENSP00000256015 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 2071 | ERCC3 | 593 | NP_000113.1 | in vitro;in vivo | 9118947 |
| 2960 | GTF2E1 | 1799 | NP_005504.2 | in vitro | 11113176 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Basal transcription factors | hsa03022 |
| Nucleotide excision repair | hsa03420 |
| Viral carcinogenesis | hsa05203 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| TIGR00625 | 18-460 | tfb2 |
| cl04289 | 18-460 | Tfb2 superfamily |
| pfam03849 | 21-374 | Tfb2 |
| COG5144 | 21-457 | TFB2 |
| pfam13625 | 326-409 | Helicase_C_3 |
| cl16326 | 326-409 | Helicase_C_3 superfamily |
Ontology Information
| HPRD ID | 15912 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Enzyme activator activity (GO:0008047) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.