CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22968445	2012	Cell line : - Source : Department of Pathology of Wrocw Medical University. Sample Type : - No. of Sample : - Stage : -	Laser capturemicrodissection,FFPE-FASP,SAX fractionation,LC-MSMS,Label-free quantitation.	Up-regulation	5.4	-

Gene Details

Chromosome: 21; NC_000021.8 (40714241..40721047, complement)
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Gene Type	protein coding
Gene Family	High-mobility group / Canonical
Description	The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]
Chromosome	21
Location	21q22.2
Start	39342315
End	39349121
Strand	-
Gene Sequence	>gi\|568815577:c39349121-39342315 Homo sapiens chromosome 21, GRCh38.p2 Primary Assembly GGGGAGGAGGAGGCGGGCTCCCAATCCGGTTCCATCCGGTTCTCCCACCGCCCCCGCTGTGGGTCTCAGC AGCTCGGGCGGCGGGAGGAGTGGCAGCGGCAAGGCAGCCCAGTTTCGCGAAGGCTGTCGGCGCGCCGCGG CCCGCAGGCACCCGGCACGCGCCTTCCCCGCAGGCACCCGGCACGCGCCTTCCCCGCCGCCACGATGCCC AAGAGGAAGGTGAGCGGCGGCCGCGGCCCGCACACGCCCCCTGGAGCCGCCGCCGGCGCCCCGCCGGGCC CCGCGAGGCCCAGGCCCCGTTGCACCCACGGTGGCGACGGGCCCGGGAGGCGCTTGGAGACCGGCGGGCG GGCAGGCGAGCGCTCGGCGGCCGCGGGGGCGGGCGTTCTGGAACGTTTGGCGGCCGGGGGAGCTGAGGGG GCTATTCGAACGGGGCGGCGGGAAGCCGTGACGTCACGCGGCCGGGCATTGTTCTCGGGGCCGGGCGGGC CCGCGAGTCCTGGGACTGCGGCCCGCCTCTATTCGTGCGTCTCCGTCTCCGCAGGTCAGCTCCGCCGAAG GCGCCGCCAAGGAAGAGGTGAGTGCGGGCCTTCTGCGGGGGGTGGTGGGTTTCCCGTGAGCCGCTGGCCT GCCTTCTCTTCTCGCTGACTCTCCTTTTTCTTTCTCCAAGCCCAAGAGGAGATCGGCGCGGTTGTCAGCT GTAAGTAAAGCGAGCCCCGTAACCGTTCGTTTTCCGCGGGTCGTCCCGGGTGAGGACGCTCAGTGCTGCT TTTGCCTTTCAGAAACCTCCTGCAAAAGTGGAAGCGAAGCCGAAAAAGGCAGCAGCGAAGGTAAGCCTCG AAACGCGCATTGGGATGCAGCGGGGCCTTAGGCTACACTGCTTCTTAATGCGGGGCTTCCATTTTGATTA GCTATTGGAGCTTTATTTATACTTTAATAATTACGGTAAATAATTTTTCTAGTGGTCGAGGCAAAAATGT AATGGATATATTCATCCTGGTTTATAGAACTATATCACACTAATGCTGCTGCAGATGTTAGGAGACTTAG GACGACAAAAAATATTAAATATTAAGTCTACAAAGGAAATTTATTCTTTGCGTTGCGTACATTGTGGCTG GTGCTTGGCTTTTAATTCGTGCTTGTACTTCCTTTTTTGACAATAAAAGAGTCAAGATAGCACCGAGGCC AGGAGAAAGGGAACGTGTAAGTTTTTATATATACAGTTTCCAAGCCAACTTCGGGAAGCCTTAACCTTTT TACGGGGTGGGGGTGGGGAGGTAAAAAGTTGTGATCTCTGAGAAAATAACCGCCACTACTCTGGAAGTGT TCATCAGCAGTTATACAAAACCGTGATTTTGGCTGCTCCCTAACAAATTCGTGATTGCATGATTCGAATT GCAGGTCTGTAGAATGAAGTTGGCTTTGGGTGTACGTGTGTTTGATAACTTGCAGGGTGGAAAAGCAGAA CATGTGTAAAACAAGTATAAGCTTTGTGTTTGGATATAGCATTGAAACCTGTAAAGCTCTACATGTTCTT CGCGGGGTGATTAATTTTTATCCAAAACTTAGGTGAGAGTTTGCTATTTGAAGTCTCAAAAAAAATTTTT GTTAATGCCTTCACCTCTTTCCTAAAAGTGTAGGTAGAAGTTTAGCACTGCAGTCATCAGAAGAGGCAAG ATTAATTTCCTTGACATTGAGGAGTTGTTGGATAATTACTAAATTTGTCCTTGTTAAATAAAGGTATAAA ACAAAGATGTTTTTTCTTTTTTAATTTAAATTTTTTACAGAGCTGAGTGTAAAAATGTTAACTATGTTTT CTTTAACAGAAAGTTCTGTTTTTGTGATCCTTTTAAAAATAAAGCTTCACGGAAGGTATGAGAATAGTAT TTTTCAACTTTAAATTTCTCATTACCAGAAGACCATGTGGTAATTCTCTGTATACAGTTAGAACAGCACG GAAACTTGAAGGCCTAAAAAATTAGCTGACCTTGTTAAAAATGTTGGCGTGAGCAGTATATTATTACCTA TCTTTTTTTATTGTGTGTGTGTGTGTGTGTGTGTTTTAAACTAATTGGCTGAAATATCTGCCTGTTTCCC TCTTTACATTTTTCTTGTTTCTTTCCTTATTTATCTTTGTCCATCTTGAGATCTACTGTAAAGTGAATTT TTTAATGAAAACAGTTCCAAGTTTTACTCTCAGTGGGTTTGGGACATCAGATGTAATTGAGAGGCCAACA GGTAAGTCTTCATGTCAGTGTTTGTTGAGGAACGAGCCTATGAGGTCAGTTTTCCCAAAAGGAAAAAGGG CAGAAGGGATTTGTTCATTTTTACATCTCGTTTCTGTAATACACCTTTGACTTCATGGTTGATCAGACTT TGAAGTCTAAACAGAACGTAAGCACTTGGTGTATCGATTATCATACTACACAGTAGACATGTTTTCAAGG CATATCTTGTCACTGTGTGTGCTTCTGACTTGTATCTTTCCCTAGAACTAAATATTTTGAAGGTCCAAAC ATTATACTTTGGGAAACTTGATTGATTTTTTTTTAATCTAGCTTTTCAGCTGATAATGGTTACACGTGGT ATTATTTCAAGTCCAAGATATTATGTATTCTATTTTAACTGTTTCCCAGTTTTGTATTTTTTGTATTGGA ATGATTATGAAATTAATGAGAAATCTTTAGAAACAGACTACAAAAGAGTAGTTCTTAAATACAGAAGTGA TTGTGAAACTTTGTGATAGCAATGTGTGTAGTAGCAGTTTTGTCTCAAATACATTTATCATTTGTTACTC AAAGGATGTTGAAGTATTAAAAGTCATTATGCTGTCTGTGGAATCCTACTATTAGTACAGAACACCCTGC AGTGATTTTTCCGCCCGTGTTAGCATTGAAGTTGTGAGCTCTACTTGCTTGTCTTTATGGCCCTTTAATT CAAGTAATTGGTCAGTATCCGTATGGGTCTTTTATACCACCCGCTGGGGGCTAAACTAATTTAGCTGCTG CTGTATACTTACTAACAAGGAATAAATGTTAAGCTTTCTTCTCAGTATTGATGGATGGTATCTAAAAGTA TTTTTATGTTTCTTTAACATGGCTTAAATTTTGAACTTAATGTATCAAGTTAGTATGGTCATATTAATAC CTGTGCTTTTCAGATTCTTCAAACACCTAAATGAAAGTGATAAATTCAAAACTGATCCTTTTAGTTCCTC ATTATATGATATGAAGGGATTAACTGTAGCAGGATAGTCAACCTGACCGTACGGCATGGTGCTTTTTTTC AGGTGATTGGTCTTAATGTGAGGGTTAAGGTCTTGTGAGGACAGTATTGTTGAAGTTCACAACAAATTTG GGGATGGGTGGGAATACGGTCGACGAGACTCCTCCGGTATTCAACTTCATGACATTGTCCTGTCATGTGG AACTGTAGGGAATAGTGGATGATGGCGACAGTGGTGAAATATAGCTCGGGCTTTAGGATTTGTCATATGT CTAATGAGGCTTGACATGCAAGTACTATTAAAATCTCCTTAGCATACATTGTTTTCCTGATTACTGGGGG GGACCTTAAGTTGTCTCATGTAATAGGTGTATCAACTGATGTGTGATAGACATTAATATGACAGCTGTTA TGGATACAGTCTATACAAAATGAGATCCTTTCATAAGCTTGAAGATTGGGGTTTCACGCTCATGTGTGAG ATGTCCCTCTCTCAAACCTTACTATGAAGTCAGCACCACTGGGCACATTACTTGTCTGACATGAAGGGGA AAAAGTAAAACAAAATGTAAATAAGGAGTAAAGCATGTACTTAAAATATATTCTTATTCTATCATAGGAT AAATCTTCAGACAAAAAAGTGCAAACAAAAGGGAAAAGGGGAGCAAAGGGAAAACAGGCCGAAGTGGCTA ACCAAGAAACTAAAGAAGACTTACCTGCGGAAAACGGGGAAACGAAGACTGAGGAGGTCAGAAGTGTGTG TGTGTGTGTGTGTGTGTGTGTGATTGCTTTGACTCTGAACAGTAGATACTAAATTGTACATTTTTTGTAG CAGATAACAGTATTCATTATAATATTGAACAAAGTTTTGTACGGTATCCCAAAGTGATTGGACAAATGGT TTTCTATGATTTATGTTATTGGAAAGTAAATATGTAAATGGCTTATTTAAGAGCAAGAAATTTTAATATG CTCAATTTCAGATATAATTCAATCTTTGTTTTGTTTTTATATTCTGGATGTTGCTTTTAAATATATTTTT GAAAATTTATTCCCCTTACTTGCATTTTTCCTGGCATTTTTTTCCCACTTTCATTTCTAATGAAAATGTT TTTGTTTGTATTTTTCTTAAAGGTCTAAATAATAACATAGATCAAGTAAATAAAAAGACTAGTGTCATTA ATCTTTATTCTTAGAGACAGTGTCTGTTAGCCAGGCTGAATCTTTATTGTTTTAAGCTGTGAGGAAAAGA TGTCTTTTTTTTTTTATTAATGAAGCAGTGGGAGTAGAGAAGGAACAAAGAAGTCTGTAACAGGTTTTGA TTGATTTGTTGTGAGCACTACTGCACTCCTCTAGCCTGGAAGCTGTTTCTTAAAAAATAACTGAACTGCA AGATTCAGTTAAGCCAGACCTTTATTTTATGTTTGTTATATTAGCTAAGCTAGAAAAGATAAGTAATTTA GTATATTGATTTTTAAATTTTGATATCACTTAAGTATTTGATGTTTATATTTGATATTTATCAAATTCTT AAGTTATAAACTACTTATTCCTAAGTTAAGAAATTTATAATCACAGTTTATTTTTTTAACTTGTACTTCT TGTACTTCTTAATTCCTTTTTTTTTTTTTTTTTTTGAGACGGAATTTCGCTCTTGTTGCCCAAGCTGGAG TGCAGTGGTGGGATCTTGGCTCACTGCATCCTCCACCTCCCGGGTTCAAGCGATTATCCTGCCTCAGCCT CCTGAGCGGCTGGGATTACAGGCGTGCATCCCCACACCCAACTAATTTTTTGTATTTTTAGTAGAAACGG GGTTTCGCCGTGTTAGCCAGGCTGGTTTCAAACTCCTGACCTCAGGTGATCTGTCCGCCTTGGCCTCACA AAGTGCTGGTATTACAGGTGTGAGCCACCGCTCCTGGCCTGTACTACTTAATTCTAACCATACATCAAAT ACTGTGTGATAATAAGATCACATTGCTAATCTAGTTTTGATTTTAAAGGAAGAACTTGACCTTCTAGTAC ATGTTATCAAATTACAGTTGGTTTCCCTTGTTTATAGCTGTGTTCTATTAATATAAGGCTGCCACAAGTA TGAAACCGTTTTCACATAGGGGAAGTACAGGATTGGGTTCCTACAAACCTCTGATCACAACATTTTCATC AACTGAAAATACGTGACTTTGTTACATGTGTATTTCTGTTTAGACATGCCTTAATGTATGTTAAATTCAC ATCGAACTCACTACCCAGTAGCACTGTAATTTGTACCTGAACAAAGCCCTCCAACACATACGTTCTCTGT GTGGCACATCACAGCCTTGAATTGAGCAACATTAGATAGCACTTGAACAAGATGCGTGGGGGCCATTTTA AACAACAAAATCATCAGTAAAAAGCACAAAGGTGTAAAATATGTGGCACTAAGTAGACCGGAAAAACAGT TGTTTACGGCATTAGAGCTGAAACAAGAAGACAGAGTGACCTCAGCTTGGAGTGTACATGTGATGCAACT CAACATTTTTTCCTGCTCTGTAGATGCATGCACATGACCATGGAAGGGCTGCAAGTATTGATTTGGGGTG AGGGGGTGGTTAACAAAAGTTTTTTAACAAGAGTAGGTAGGTGACTTTACAAATAACAAAGGTTATTGAC TTTTTTAAAGACCTGATAGTTGCATATAAATAAAACGACAACGTGTTAAATGCTAAAGATCTCAATTTCC TTTCTTTTGCAGAGTCCAGCCTCTGATGAAGCAGGAGAGAAAGAAGCCAAGTCTGATTAATAACCATATA CCATGTCTTATCAGTGGTCCCTGTCTCCCTTCTTGTACAATCCAGAGGAATATTTTTATCAACTATTTTG TAAATGCAAGTTTTTTAGTAGCTCTAGAAACATTTTTAAGAAGGAGGGAATCCCACCTCATCCCATTTTT TAAGTGTAAATGCTTTTTTTTAAGAGGTGAAATCATTTGCTGGTTGTTTATTTTTTGGTACAACCAGAAA ATAGTGTGGGATATTGAATTATGGGAGGCTCTGACTGTCTCGGGTGTCAGCTTAACATTCCACAGATGGG GGGTTAGTTTTTATATCCTATAATACAAAGCATATTAAATGGCAATATGGAGTCAGTCCTGCATTTAATG TCTTGAACATTTTAAATTACTTCTATTACCATGTTGTTTTTTAGTAGAATTGTTTCCTAAAGAAAACCAC TCTTTGATCATGGCTCTCTCTGCCAGAATTGTGTGCACTCTGTAACATCTTTGTGGTAGTCCTGTTTTCC TAATAACTTTGTTACTGTGCTGTGAAAGATTACAGATTTGAACATGTAGTGTACGTGCTGTTGAGTTGTG AACTGGTGGGCCGTATGTAACAGCTGACCAACGTGAAGATACTGGTACTTGATAGCCTCTTAAGGAAAAT TTGCTTCCAAATTTTAAGCTGGAAAGTCACTGGAATAACTTTAAAAAAGAATTACAATACATGGCTTTTT AGAATTTCGTTACGTATGTTAAGATTTGTGTACAAATTGAAATGTCTGTACTGATCCTCAACCAATAAAA TCTCAGTTATGAAAATA Download Select all
Length	6807
OMIM ID	163920
HGNC ID	HGNC:4984
Unigene ID	Hs.356285
Ensembl ID	ENSG00000205581
PharmGKB ID	PA35088

mRNA Information

mRNA ID	NM_004965.6
Exon	join(1..219,545..577,671..700,783..830,3848..3976, 5963..6807)
mRNA Sequence	>3150 GGGGAGGAGGAGGCGGGCTCCCAATCCGGTTCCATCCGGTTCTCCCACCGCCCCCGCTGTGGGT CTCAGCAGCTCGGGCGGCGGGAGGAGTGGCAGCGGCAAGGCAGCCCAGTTTCGCGAAGGCTGTC GGCGCGCCGCGGCCCGCAGGCACCCGGCACGCGCCTTCCCCGCAGGCACCCGGCACGCGCCTTC CCCGCCGCCACGATGCCCAAGAGGAAGGTCAGCTCCGCCGAAGGCGCCGCCAAGGAAGAGCCCA AGAGGAGATCGGCGCGGTTGTCAGCTAAACCTCCTGCAAAAGTGGAAGCGAAGCCGAAAAAGGC AGCAGCGAAGGATAAATCTTCAGACAAAAAAGTGCAAACAAAAGGGAAAAGGGGAGCAAAGGGA AAACAGGCCGAAGTGGCTAACCAAGAAACTAAAGAAGACTTACCTGCGGAAAACGGGGAAACGA AGACTGAGGAGAGTCCAGCCTCTGATGAAGCAGGAGAGAAAGAAGCCAAGTCTGATTAATAACC ATATACCATGTCTTATCAGTGGTCCCTGTCTCCCTTCTTGTACAATCCAGAGGAATATTTTTAT CAACTATTTTGTAAATGCAAGTTTTTTAGTAGCTCTAGAAACATTTTTAAGAAGGAGGGAATCC CACCTCATCCCATTTTTTAAGTGTAAATGCTTTTTTTTAAGAGGTGAAATCATTTGCTGGTTGT TTATTTTTTGGTACAACCAGAAAATAGTGTGGGATATTGAATTATGGGAGGCTCTGACTGTCTC GGGTGTCAGCTTAACATTCCACAGATGGGGGGTTAGTTTTTATATCCTATAATACAAAGCATAT TAAATGGCAATATGGAGTCAGTCCTGCATTTAATGTCTTGAACATTTTAAATTACTTCTATTAC CATGTTGTTTTTTAGTAGAATTGTTTCCTAAAGAAAACCACTCTTTGATCATGGCTCTCTCTGC CAGAATTGTGTGCACTCTGTAACATCTTTGTGGTAGTCCTGTTTTCCTAATAACTTTGTTACTG TGCTGTGAAAGATTACAGATTTGAACATGTAGTGTACGTGCTGTTGAGTTGTGAACTGGTGGGC CGTATGTAACAGCTGACCAACGTGAAGATACTGGTACTTGATAGCCTCTTAAGGAAAATTTGCT TCCAAATTTTAAGCTGGAAAGTCACTGGAATAACTTTAAAAAAGAATTACAATACATGGCTTTT TAGAATTTCGTTACGTATGTTAAGATTTGTGTACAAATTGAAATGTCTGTACTGATCCTCAACC AATAAAATCTCAGTTATGAAAATAAAAAAAAAA Download Select all
Length	1313

CDS Information

Location	join(3276..3292,3848..3976,5963..6323)
CDS Sequence	>gi\|48255932:205-507 Homo sapiens high mobility group nucleosome binding domain 1 (HMGN1), mRNA ATGCCCAAGAGGAAGGTCAGCTCCGCCGAAGGCGCCGCCAAGGAAGAGCCCAAGAGGAGATCGGCGCGGT TGTCAGCTAAACCTCCTGCAAAAGTGGAAGCGAAGCCGAAAAAGGCAGCAGCGAAGGATAAATCTTCAGA CAAAAAAGTGCAAACAAAAGGGAAAAGGGGAGCAAAGGGAAAACAGGCCGAAGTGGCTAACCAAGAAACT AAAGAAGACTTACCTGCGGAAAACGGGGAAACGAAGACTGAGGAGAGTCCAGCCTCTGATGAAGCAGGAG AGAAAGAAGCCAAGTCTGATTAA Download Select all
CCDS ID	-

Protein Information

Protein ID	NP_004956.5
Protein Name	High-mobility group nucleosome binding domain 1
Molecular Wt. (Da)	10528
Protein Sequence	>3150 MPKRKVSSAEGAAKEEPKRRSARLSAKPPAKVEAKPKKAAAKDKSSDKKVQTKGKRGAKGKQAE VANQETKEDLPAENGETKTEESPASDEAGEKEAKSD Download Select all
Length	100
Uniprot ID	Q05682
Ensembl Protein ID	ENSP00000354826

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	70
S	Phosphorylation	86
S	Phosphorylation	21
S	Phosphorylation	25
S	Phosphorylation	7
S	Phosphorylation	21
S	Phosphorylation	25
S	Phosphorylation	7
S	Phosphorylation	21
S	Phosphorylation	25
S	Phosphorylation	7
K	Acetylation	14
K	Acetylation	18
K	Acetylation	27
K	Acetylation	31
K	Acetylation	38
K	Acetylation	3
K	Acetylation	48
K	Acetylation	53
K	Acetylation	55
K	Acetylation	61
K	Acetylation	82
S	Phosphorylation	7
S	Phosphorylation	7
S	Phosphorylation	89
S	Phosphorylation	8
T	Phosphorylation	83
S	Phosphorylation	99
T	Phosphorylation	81

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
3151	HMGN2	1230	NP_005508.1	in vitro	7563062
3660	IRF2	962	NP_002190.2	in vitro;in vivo;yeast 2-hybrid	11025449

Pathway Information

Pathway Name	Pathway ID
Herpes simplex infection	hsa05168

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
smart00527	Feb-92	HMG17
cl12114	Feb-92	HMG14_17 superfamily
pfam01101	Feb-96	HMG14_17

Ontology Information

HPRD ID	251
Molecular Class	Transcription regulatory protein
Molecular Function	Cytoskeletal protein binding (GO:0008092)
Biological Process	Cell growth and/or maintenance (GO:0008151)

SNP Information

View SNP Geneview Report