Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| HTATIP2 | 10553 | HIV-1 Tat interactive protein 2, 30kDa  | 11 | TIP30, CC3, FLJ26963, SDR44U1  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23591201    | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 462 Stage : - | Tissue microarray and immunohistochemistry | Up-regulation | - | Kaplan-Meier analysis demonstrated that patients with high expression of CC3 in the tumour or CC3 or cleaved PARP in tumour-associated stroma have a good prognosis. On multivariate analysis, using Cox's proportional hazards model, tumour stage, vascular invasion and expression of CC3 in tumour-associated stroma were shown to be independent markers of prognosis |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Short chain dehydrogenase/reductase superfamily / Atypical members |
| Description | -   | Chromosome | 11 |
| Location | 11p15.1 |
| Start | 20363685   |
| End | 20383783   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 20099   |
| OMIM ID | 605628    |
| HGNC ID | HGNC:16637    |
| Unigene ID | Hs.90753    |
| Ensembl ID | ENSG00000109854    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_006410.4 |
|---|---|
| Exon | join(1..65,553..748,3490..3597,12896..13033,18494..18555, 19296..20099)   | mRNA Sequence |    Download   Select all |
| Length | 1509   |
CDS Information
| Location | join(128..228,553..748,3490..3597,12896..13033, 18494..18555,19296..19521) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS44553.1 |    
Protein Information
| Protein ID | NP_001091990.1 |
|---|---|
| Protein Name | HIV-1 Tat interactive protein 2, 30kDa |
| Molecular Wt. (Da) | 0 |
| Protein Sequence |    Download   Select all |
| Length | 0   |
| Uniprot ID | Q13683 |    
| Ensembl Protein ID | ENSP00000257879   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 20 |
| S | Phosphorylation | 54 |
| S | Phosphorylation | 20 |
| S | Phosphorylation | 20 |
| S | Phosphorylation | 20 |
| S | Phosphorylation | 8 |
| S | Phosphorylation | 42 |
| S | Phosphorylation | 8 |
| S | Phosphorylation | 8 |
| S | Phosphorylation | 8 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 2113 |    ETS1 |    1260 |    NP_001137292.1 |    in vitro;in vivo |    18537194    |
| 57727 |    NCOA5 |    14813 |    NP_066018.1 |    in vitro |    15073177    |
Pathway Information
No matching records could be found.
Structure Information
| PDB ID | 2BKA |
|---|---|
| Resolution | 1.7 |
| Method | X-RAY DIFFRACTION |
| Chains | A   |
| Molecule | TAT-INTERACTING PROTEIN TIP30   |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05250 | 19-231  | CC3_like_SDR_a |
| cl21454 | 19-231  | NADB_Rossmann superfamily |
| cd05226 | 21-221  | SDR_e_a |
| cd05243 | 21-171  | SDR_a5 |
| cd05269 | 23-168  | TMR_SDR_a |
| cd05271 | 21-169  | NDUFA9_like_SDR_a |
| cd05244 | 23-218  | BVR-B_like_SDR_a |
| cd05259 | 20-127  | PCBER_SDR_a |
| cd05231 | 23-136  | NmrA_TMR_like_1_SDR_a |
| cd05267 | 19-105  | SDR_a6 |
| cd05245 | 21-171  | SDR_a2 |
| smart00859 | 20-93  | Semialdhyde_dh |
| pfam01118 | 21-93  | Semialdhyde_dh |
| cd05265 | 19-171  | SDR_a1 |
| pfam13460 | 23-170  | NAD_binding_10 |
| COG0702 | 21-171  | YbjT |
| COG0451 | 19-193  | WcaG |
| PLN02657 | 12-167  | PLN02657 |
| COG3320 | 116-219  | Lys2b |
| TIGR01296 | 20-106  | asd_B |
| TIGR01035 | 19-96  | hemA |
| pfam03435 | 21-123  | Saccharop_dh |
Ontology Information
| HPRD ID | 628 |    
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Receptor activity (GO:0004872) |
| Biological Process | Cell communication (GO:0007154); Immune cell migration (GO:0050900)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
