Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
HTATIP2 10553 HIV-1 Tat interactive protein 2, 30kDa  11TIP30, CC3, FLJ26963, SDR44U1 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
23591201   2013Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 462

Stage : -

Tissue microarray and immunohistochemistryUp-regulation-Kaplan-Meier analysis demonstrated that patients with high expression of CC3 in the tumour or CC3 or cleaved PARP in tumour-associated stroma have a good prognosis.

On multivariate analysis, using Cox's proportional hazards model, tumour stage, vascular invasion and expression of CC3 in tumour-associated stroma were shown to be independent markers of prognosis


Gene Details



Chromosome 11 - NC_000011.1020363685..20383783)

View Larger Image
   
Gene Type protein coding
Gene Family Short chain dehydrogenase/reductase superfamily / Atypical members
Description -  
Chromosome 11
Location 11p15.1
Start 20363685  
End 20383783  
Strand +  
Gene Sequence

   Download   Select all

Length 20099  
OMIM ID 605628   
HGNC ID HGNC:16637   
Unigene ID Hs.90753   
Ensembl ID ENSG00000109854   
PharmGKB ID -   

mRNA Information


mRNA ID NM_006410.4
Exon join(1..65,553..748,3490..3597,12896..13033,18494..18555, 19296..20099)  
mRNA Sequence

   Download   Select all

Length 1509  



CDS Information


   
Location join(128..228,553..748,3490..3597,12896..13033, 18494..18555,19296..19521)
CDS Sequence

   Download   Select all

CCDS ID CCDS44553.1



Protein Information


      
Protein IDNP_001091990.1
Protein NameHIV-1 Tat interactive protein 2, 30kDa
Molecular Wt. (Da)0
Protein Sequence

   Download   Select all

Length 0  
Uniprot IDQ13683
Ensembl Protein ID ENSP00000257879  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation20
SPhosphorylation54
SPhosphorylation20
SPhosphorylation20
SPhosphorylation20
SPhosphorylation8
SPhosphorylation42
SPhosphorylation8
SPhosphorylation8
SPhosphorylation8

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                              
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
2113ETS11260NP_001137292.1in vitro;in vivo18537194   
57727NCOA514813NP_066018.1in vitro15073177   


Pathway Information


No matching records could be found.

Structure Information


PDB ID2BKA
Resolution1.7
MethodX-RAY DIFFRACTION
Chains A  
Molecule TAT-INTERACTING PROTEIN TIP30  
Model View



Domain Information




ID Location Description
cd0525019-231  CC3_like_SDR_a
cl2145419-231  NADB_Rossmann superfamily
cd0522621-221  SDR_e_a
cd0524321-171  SDR_a5
cd0526923-168  TMR_SDR_a
cd0527121-169  NDUFA9_like_SDR_a
cd0524423-218  BVR-B_like_SDR_a
cd0525920-127  PCBER_SDR_a
cd0523123-136  NmrA_TMR_like_1_SDR_a
cd0526719-105  SDR_a6
cd0524521-171  SDR_a2
smart0085920-93  Semialdhyde_dh
pfam0111821-93  Semialdhyde_dh
cd0526519-171  SDR_a1
pfam1346023-170  NAD_binding_10
COG070221-171  YbjT
COG045119-193  WcaG
PLN0265712-167  PLN02657
COG3320116-219  Lys2b
TIGR0129620-106  asd_B
TIGR0103519-96  hemA
pfam0343521-123  Saccharop_dh


Ontology Information


   
HPRD ID628
Molecular ClassTranscription regulatory protein
Molecular FunctionReceptor activity (GO:0004872)
Biological ProcessCell communication (GO:0007154); Immune cell migration (GO:0050900)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO