Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| IFNA1 | 3439 | Interferon, alpha 1 | 9 | IFL; IFN; IFNA@; IFNA13; IFN-ALPHA; IFN-alphaD |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 9792144 | 1998 | Cell line : - Source : - Sample Type : Blood sample No. of Sample : 28 CRC patients and 44 healthy persons Stage : - | Whole blood cell culture and stimulation of cytokine secretion, ELISA. | Down-regulation | - | The differential expression of Blood protien were analysed by ELISA in colorectal cancer and normal colorectal tissue. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Interferons |
| Description | The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011] | Chromosome | 9 |
| Location | 9p22 |
| Start | 21440454 |
| End | 21441316 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 863 |
| OMIM ID | 147660 |
| HGNC ID | HGNC:5417 |
| Unigene ID | Hs.37026 |
| Ensembl ID | ENSG00000197919 |
| PharmGKB ID | - |
Protein Information
| Protein ID | NP_076918.1 |
|---|---|
| Protein Name | Interferon, alpha 1 |
| Molecular Wt. (Da) | 19386 |
| Protein Sequence | Download Select all |
| Length | 189 |
| Uniprot ID | Q03135 |
| Ensembl Protein ID | ENSP00000339191 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1380 | CR2 | 399 | NP_001006659.1 | in vivo | 1849076 |
| 10379 | IRF9 | 960 | NP_006075.3 | in vitro | 8454630 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Autoimmune thyroid disease | hsa05320 |
| Cytokine-cytokine receptor interaction | hsa04060 |
| Cytosolic DNA-sensing pathway | hsa04623 |
| Hepatitis B | hsa05161 |
| Hepatitis C | hsa05160 |
| Herpes simplex infection | hsa05168 |
| Influenza A | hsa05164 |
| Jak-STAT signaling pathway | hsa04630 |
| Measles | hsa05162 |
| Natural killer cell mediated cytotoxicity | hsa04650 |
| PI3K-Akt signaling pathway | hsa04151 |
| Regulation of autophagy | hsa04140 |
| RIG-I-like receptor signaling pathway | hsa04622 |
| Toll-like receptor signaling pathway | hsa04620 |
| Tuberculosis | hsa05152 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00095 | 26-178 | IFab |
| cl00092 | 26-178 | IFab superfamily |
| pfam00143 | 26-187 | Interferon |
| smart00076 | 58-175 | IFabd |
Ontology Information
| HPRD ID | 2565 |
|---|---|
| Molecular Class | Cytokine |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.