Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| IL22 | 50616 | interleukin 22 | 12 | ILTIF, IL-21, zcyto18, IL-TIF, IL-D110, TIFa, TIFIL-23, IL-22, MGC79382, MGC79384 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26130064 | 2015 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | - | Up-regulation | - | A significantly higher expression of IL22R1 and IL10R2 was also confirmed in a separate cohort of colorectal cancer samples. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Interleukins and interleukin receptors |
| Description | - | Chromosome | 12 |
| Location | 12q15 |
| Start | 68642025 |
| End | 68647379 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 5355 |
| OMIM ID | 605330 |
| HGNC ID | HGNC:14900 |
| Unigene ID | Hs.287369 |
| Ensembl ID | ENSG00000127318 |
| PharmGKB ID | PA29822 |
Protein Information
| Protein ID | NP_065386.1 |
|---|---|
| Protein Name | interleukin 22 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 179 |
| Uniprot ID | Q9P287 |
| Ensembl Protein ID | ENSP00000278100 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| C | Disulfide Bridge | 40;132 |
| C | Disulfide Bridge | 89;178 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 3588 | IL10RB | 473 | NP_000619.3 | in vivo | 10875937 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Cytokine-cytokine receptor interaction | hsa04060 |
| Inflammatory bowel disease (IBD) | hsa05321 |
| Jak-STAT signaling pathway | hsa04630 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam14565 | 40-178 | IL22 |
| cl02501 | 40-178 | IL10 superfamily |
| pfam00726 | 89-170 | IL10 |
| smart00188 | 89-170 | IL10 |
Ontology Information
| HPRD ID | 5952 |
|---|---|
| Molecular Class | Cytokine |
| Molecular Function | Serine-type peptidase activity (GO:0008236) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.