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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 10747296 | 2000 | Cell line : - Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 49 Stage : - | Reverse Northern dot blotting,Taqman RT-PCR | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008] | Chromosome | 2 |
| Location | 2q32 |
| Start | 191208196 |
| End | 191236391 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 28196 |
| OMIM ID | 147263 |
| HGNC ID | HGNC:6071 |
| Unigene ID | Hs.32309 |
| Ensembl ID | ENSG00000151689 |
| PharmGKB ID | PA29880 |
mRNA Information
| mRNA ID | XM_011512286.1 |
|---|---|
| Exon | complement(<1..491) | mRNA Sequence | Download Select all |
| Length | 1517 |
Protein Information
| Protein ID | XP_011510588.1 |
|---|---|
| Protein Name | inositol polyphosphate-1-phosphatase |
| Molecular Wt. (Da) | 18812 |
| Protein Sequence | Download Select all |
| Length | 170 |
| Uniprot ID | Q16658 |
| Ensembl Protein ID | ENSP00000371798 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 3978 | LIG1 | 534 | NP_000225.1 | yeast 2-hybrid | 16169070 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Inositol phosphate metabolism | hsa00562 |
| Metabolic pathways | hsa01100 |
| Phosphatidylinositol signaling system | hsa04070 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd01640 | 4-387 | IPPase |
| cl00289 | 4-387 | FIG superfamily |
| pfam00459 | 56-379 | Inositol_P |
| cd01636 | 5-334 | FIG |
| cd01637 | 6-337 | IMPase_like |
| cd01638 | 151-335 | CysQ |
| COG1218 | 151-334 | CysQ |
| TIGR01331 | 152-336 | bisphos_cysQ |
| COG0483 | 150-334 | SuhB |
| cd01641 | 151-334 | Bacterial_IMPase_like_1 |
| TIGR02067 | 151-333 | his_9_HisN |
| cd01643 | 150-343 | Bacterial_IMPase_like_2 |
Ontology Information
| HPRD ID | 2490 |
|---|---|
| Molecular Class | Enzyme: Phosphohydrolase |
| Molecular Function | Receptor signaling complex scaffold activity (GO:0030159) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.