Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| INPP4B | 8821 | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26411369 | 2015 | Cell line : - Source : Sakura Finechemicals, Tokyo, Japan and frozen. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Laser capture microdissection,qPCR array,Chromatin immunoprecepetation | Unknown | - | INPP4B�may function as an oncogenic driver in colon�cancer |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008] | Chromosome | 4 |
| Location | 4q31.1 |
| Start | 142949181 |
| End | 143767604 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 818424 |
| OMIM ID | 607494 |
| HGNC ID | HGNC:6075 |
| Unigene ID | Hs.531403 |
| Ensembl ID | - |
| PharmGKB ID | PA29883 |
Protein Information
| Protein ID | NP_001095139.1 |
|---|---|
| Protein Name | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 924 |
| Uniprot ID | O14522 |
| Ensembl Protein ID | ENSP00000362283 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 792;- |
| S | Phosphorylation | 794;- |
| T | Phosphorylation | 198 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Inositol phosphate metabolism | hsa00562 |
| Metabolic pathways | hsa01100 |
| Phosphatidylinositol signaling system | hsa04070 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd04048 | 39-175 | C2A_Copine |
| cl14603 | 39-175 | C2 superfamily |
| cd00030 | 44-160 | C2 |
Ontology Information
| HPRD ID | 4688 |
|---|---|
| Molecular Class | Enzyme: Phosphotransferase |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.