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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
IPO4 79711 Importin 4  14Imp4 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22968445   2012Cell line : -

Source : Department of Pathology of Wrocaw Medical University.

Sample Type : CRC tumor and normal tissue

No. of Sample : 8

Stage : -

Laser capture microdissection,FF E-FASP,SAX fractionation,LC MSMS,Label-free quantitation.Up-regulation3.9-


Gene Details



Chromosome: 14; NC_000014.8 (24649425..24658124, complement)

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Gene Type protein coding
Gene Family Importins
Description -  
Chromosome 14
Location 14q12
Start 24180219  
End 24188918  
Strand +  
Gene Sequence

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Length 8700  
OMIM ID    
HGNC ID HGNC:19426   
Unigene ID Hs.411865    
Ensembl ID ENSG00000196497   
PharmGKB ID -   

mRNA Information


mRNA ID XM_011537421.1
Exon complement(<8511..>8700)  
mRNA Sequence

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Length 3606  



CDS Information


   
Location complement(<8651..>8700)
CDS Sequence

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CCDS ID -



Protein Information


      
Protein IDNP_078934.3
Protein NameImportin 4
Molecular Wt. (Da)118585
Protein Sequence

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Length 1081  
Uniprot IDO43524
Ensembl Protein ID ENSP00000339527  



Post-translational Modification Information (Source : HPRD)


Residue Type site
TPhosphorylation86

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd00020355-467  ARM
cl22454355-467  ARM superfamily
smart0091324-90  IBN_N
cl0427124-90  IBN_N superfamily
pfam13513366-421  HEAT_EZ
pfam13646392-505  HEAT_2
COG5215357-620  KAP95
COG5181351-501  HSH155
pfam01602335-505  Adaptin_N


Ontology Information


   
HPRD ID635
Molecular ClassTransport/cargo protein
Molecular FunctionTransmembrane receptor protein tyrosine kinase activity (GO:0004714)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO