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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 10874008 | 2000 | Cell line : - Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 24 Stage : - | Western immunoblotting,immunohistochemistry | Up-regulation | - | JunB proteins were undetectable or barely detectable in normal mucosa but their expression levels were significantly increased in human colorectal adenocarcinomas. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | basic leucine zipper proteins |
| Description | - | Chromosome | 19 |
| Location | 19p13.13 |
| Start | 12902310 |
| End | 12904125 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 1816 |
| OMIM ID | 165161 |
| HGNC ID | HGNC:6205 |
| Unigene ID | Hs.25292 |
| Ensembl ID | - |
| PharmGKB ID | PA30007 |
Protein Information
| Protein ID | NP_002220.1 |
|---|---|
| Protein Name | jun B proto-oncogene |
| Molecular Wt. (Da) | 35043 |
| Protein Sequence | Download Select all |
| Length | 347 |
| Uniprot ID | P40763 |
| Ensembl Protein ID | ENSP00000264657 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 259 |
| T | Phosphorylation | 102 |
| T | Phosphorylation | 104 |
| T | Phosphorylation | 102 |
| T | Phosphorylation | 104 |
| T | Phosphorylation | 255;- |
| S | Phosphorylation | 117 |
| S | Phosphorylation | 251 |
| S | Phosphorylation | 311 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 604 | BCL6 | 180 | NP_620309.1 | in vitro;in vivo | 12165517 |
| 672 | BRCA1 | 218 | NP_009231.2 | in vitro;in vivo;yeast 2-hybrid | 12080089 |
| 2354 | FOSB | 1270 | NP_006723.2 | in vitro | 12371906 |
| 4779 | NFE2L1 | 1223 | NP_003195.1 | in vitro | 9872330 |
| 8061 | FOSL1 | 643 | NP_005429.1 | in vitro | 12371906 |
| 22981 | NINL | 11120 | NP_079452.3 | yeast 2-hybrid | 16189514 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Osteoclast differentiation | hsa04380 |
| TNF signaling pathway | hsa04668 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14696 | 270-329 | bZIP_Jun |
| cl21462 | 270-329 | bZIP superfamily |
| pfam00170 | 271-329 | bZIP_1 |
| smart00338 | 266-329 | BRLZ |
| cd14687 | 273-329 | bZIP_ATF2 |
| cd14691 | 270-327 | bZIP_XBP1 |
| cd14686 | 272-328 | bZIP |
| cd12193 | 270-326 | bZIP_GCN4 |
| pfam07716 | 272-326 | bZIP_2 |
| cd14690 | 270-328 | bZIP_CREB1 |
| cd14720 | 273-328 | bZIP_NFE2-like |
| cd14699 | 270-325 | bZIP_Fos_like |
| cd14698 | 265-328 | bZIP_CNC |
| pfam03131 | 264-327 | bZIP_Maf |
| cd14692 | 270-326 | bZIP_ATF4 |
| cd14703 | 273-322 | bZIP_plant_RF2 |
| cd14719 | 273-327 | bZIP_BACH |
| cd14810 | 272-321 | bZIP_u1 |
| cd14809 | 272-323 | bZIP_AUREO-like |
| cd14704 | 272-320 | bZIP_HY5-like |
| cd14688 | 272-327 | bZIP_YAP |
| cd14812 | 270-310 | bZIP_u3 |
| cd14722 | 270-324 | bZIP_ATF3 |
| cd14697 | 264-328 | bZIP_Maf |
| cd14702 | 272-320 | bZIP_plant_GBF1 |
| cd14721 | 270-331 | bZIP_Fos |
| cd14709 | 270-329 | bZIP_CREBL2 |
| cd14705 | 274-325 | bZIP_Zip1 |
| cd14700 | 266-321 | bZIP_ATF6 |
| cd14693 | 273-325 | bZIP_CEBP |
| cd14689 | 270-326 | bZIP_CREB3 |
| cd14710 | 267-322 | bZIP_HAC1-like |
| cd14713 | 273-326 | bZIP_CEBPG |
| cd14811 | 272-307 | bZIP_u2 |
| cd14695 | 274-330 | bZIP_HLF |
| cd14701 | 270-325 | bZIP_BATF |
| cd14706 | 277-324 | bZIP_CREBZF |
| cd14717 | 264-327 | bZIP_Maf_small |
| cd14707 | 273-327 | bZIP_plant_BZIP46 |
| pfam03957 | 5-257 | Jun |
| COG1842 | 267-328 | PspA |
| pfam04012 | 263-328 | PspA_IM30 |
Ontology Information
| HPRD ID | 2779 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.