Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| KDM6B | 23135 | lysine (K)-specific demethylase 6B | 17 | KIAA0346 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26416711 | 2015 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 151 Stage : - | real time RT-PCR and western blotting | Up-regulation | - | JMJD3 has prognostic significance in CRC and mediates p15INK4B expression. These results imply that elucidation of the JMJD3 role may lead to a new therapeutic approach for CRC patients. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Chromatin-modifying enzymes / K-demethylases |
| Description | - | Chromosome | 17 |
| Location | 17p13.1 |
| Start | 7737521 |
| End | 7758118 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 20598 |
| OMIM ID | 611577 |
| HGNC ID | HGNC:29012 |
| Unigene ID | Hs.223678 |
| Ensembl ID | - |
| PharmGKB ID | - |
Protein Information
| Protein ID | NP_001073893.1 |
|---|---|
| Protein Name | lysine (K)-specific demethylase 6B |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1643 |
| Uniprot ID | Q9NZF1 |
| Ensembl Protein ID | ENSP00000309509 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam02373 | 1377-1485 | JmjC |
| cl22893 | 1377-1485 | JmjC superfamily |
| smart00558 | 1343-1407 | JmjC |
| cl22893 | 1343-1407 | JmjC superfamily |
| PRK14950 | 572-718 | PRK14950 |
| PRK12323 | 566-739 | PRK12323 |
Ontology Information
| HPRD ID | 4119 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Protein serine/threonine kinase activity (GO:0004674) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091) |
Drug Information
No matching records could be found.