Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
LAMB4 22798 laminin, beta 4  7- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
23585368   2013Cell line : -

Source : -

Sample Type : -

No. of Sample : -

Stage : -

-Mutation-Somatic mutations in the corresponding genes in the CRCs of the patients harboring the germline lesions and found biallelic inactivation of FANCM, LAMB4, PTCHD3, LAMC3, and TREX2, potentially implicating these genes as tumor suppressors.

25257191   2015Cell line : -

Source : Koreans patients

Sample Type : CRC tumor

No. of Sample : 139

Stage : TNM Stage I-IV

SSCP,DNA sequencing, immunohistochemistryMutation-Frameshift mutations of LAMA1, LAMA3, LAMB1 and LAMB4, and loss of LAMB4 may be features of GC and CRC with MSI-H.


Gene Details



NC_000007.13 (107663996..107770801, complement)

View Larger Image
   
Gene Type protein coding
Gene Family Laminins
Description -  
Chromosome 7
Location 7q31
Start 107663996  
End 107770801  
Strand -  
Gene Sequence

   Download   Select all

Length 106806  
OMIM ID -   
HGNC ID HGNC:6491   
Unigene ID Hs.62022   
Ensembl ID ENSG00000091128   
PharmGKB ID PA30279   

mRNA Information


mRNA ID ?NM_007356.2
Exon  
mRNA Sequence

   Download   Select all

Length  



CDS Information


   
Location
CDS Sequence

   Download   Select all

CCDS ID CCDS34732.1



Protein Information


      
Protein IDNP_031382.2
Protein Namelaminin, beta 4
Molecular Wt. (Da)0
Protein Sequence

   Download   Select all

Length 1761  
Uniprot IDQ9BZS1
Ensembl Protein ID ENSP00000365372  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


                                          
Pathway Name Pathway ID
Amoebiasis hsa05146
ECM-receptor interaction hsa04512
Focal adhesion hsa04510
Pathways in cancer hsa05200
PI3K-Akt signaling pathway hsa04151
Small cell lung cancer hsa05222
Toxoplasmosis hsa05145


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd00055454-503  EGF_Lam
cl22875454-503  EGF_Lam superfamily
cd00055505-549  EGF_Lam
cl22875505-549  EGF_Lam superfamily
cd000551079-1121  EGF_Lam
cl228751079-1121  EGF_Lam superfamily
cd000551127-1165  EGF_Lam
cl228751127-1165  EGF_Lam superfamily
cd00055394-453  EGF_Lam
cl22875394-453  EGF_Lam superfamily
cd00055768-809  EGF_Lam
cl22875768-809  EGF_Lam superfamily
cd000551021-1078  EGF_Lam
cl228751021-1078  EGF_Lam superfamily
cd00055822-859  EGF_Lam
cl22875822-859  EGF_Lam superfamily
cd00055862-909  EGF_Lam
cl22875862-909  EGF_Lam superfamily
cd00055264-320  EGF_Lam
cl22875264-320  EGF_Lam superfamily
cd00055969-1020  EGF_Lam
cl22875969-1020  EGF_Lam superfamily
cd00055331-384  EGF_Lam
cl22875331-384  EGF_Lam superfamily
pfam0005528-263  Laminin_N
cl0280628-263  Laminin_N superfamily
smart0013623-263  LamNT
pfam000531080-1128  Laminin_EGF
smart001801080-1125  EGF_Lam
pfam00053395-452  Laminin_EGF
pfam00053455-508  Laminin_EGF
smart00180506-549  EGF_Lam
pfam00053822-865  Laminin_EGF
smart001801128-1172  EGF_Lam
pfam000531128-1165  Laminin_EGF
smart00180455-503  EGF_Lam
pfam00053769-809  Laminin_EGF
pfam000531033-1077  Laminin_EGF
smart001801022-1077  EGF_Lam
smart00180395-448  EGF_Lam
smart00180769-808  EGF_Lam
smart00180822-860  EGF_Lam
pfam00053970-1016  Laminin_EGF
pfam00053506-544  Laminin_EGF
pfam00053332-383  Laminin_EGF
pfam127181647-1756  Tropomyosin_1
cl228571647-1756  Tropomyosin_1 superfamily
pfam00053863-908  Laminin_EGF
pfam00053265-323  Laminin_EGF
smart00180332-382  EGF_Lam
smart00180863-905  EGF_Lam
smart00180970-1013  EGF_Lam
smart00180291-313  EGF_Lam
TIGR024731566-1679  flagell_FliJ
cl214771566-1679  FliJ superfamily
pfam00053938-967  Laminin_EGF
cl22875938-967  EGF_Lam superfamily
pfam079261601-1746  TPR_MLP1_2
TIGR045231413-1754  Mplasa_alph_rch
TIGR045231254-1755  Mplasa_alph_rch
TIGR045231248-1758  Mplasa_alph_rch
COG04191220-1758  SbcC
TIGR021681410-1726  SMC_prok_B
COG04191250-1749  SbcC
TIGR045231426-1755  Mplasa_alph_rch
COG11961189-1758  Smc
COG11961184-1754  Smc
TIGR045231253-1754  Mplasa_alph_rch
COG11961417-1721  Smc
COG11961419-1758  Smc
TIGR016121223-1747  235kDa-fam
TIGR021681566-1758  SMC_prok_B
TIGR021681526-1755  SMC_prok_B
COG11961443-1757  Smc
PRK039181462-1754  PRK03918
COG15791614-1755  COG1579
TIGR006181516-1755  sbcc
COG11961571-1758  Smc
TIGR021691410-1758  SMC_prok_A
TIGR006181241-1759  sbcc
pfam059111399-1743  DUF869
COG11961420-1759  Smc
PTZ004401247-1755  PTZ00440
TIGR021691420-1720  SMC_prok_A
pfam015761255-1751  Myosin_tail_1
TIGR021681439-1758  SMC_prok_B
pfam056221432-1759  HOOK
PRK039181186-1752  PRK03918
pfam101741419-1753  Cast
pfam015761587-1755  Myosin_tail_1
PTZ004401257-1755  PTZ00440
TIGR021681243-1706  SMC_prok_B
pfam054831186-1756  SCP-1
COG43721564-1760  COG4372
TIGR021691568-1758  SMC_prok_A
TIGR021691569-1758  SMC_prok_A
PHA025621413-1639  46
pfam055571421-1758  MAD
pfam097261575-1751  Macoilin
COG38831420-1663  CwlO1
pfam097301564-1749  BicD
pfam121281412-1759  DUF3584
TIGR021681595-1755  SMC_prok_B
PRK039181225-1756  PRK03918
pfam150701434-1703  GOLGA2L5
PTZ001211417-1755  PTZ00121
pfam000381420-1749  Filament
TIGR021691186-1383  SMC_prok_A
pfam155581574-1755  DUF4659
COG32061438-1753  GumC
pfam154501432-1753  DUF4631
TIGR033461633-1751  chaperone_ClpB
pfam121281417-1739  DUF3584
pfam015761185-1714  Myosin_tail_1
smart007871624-1759  Spc7
TIGR033191598-1722  RNase_Y
pfam060081626-1758  Laminin_I
pfam055571596-1755  MAD
COG13401420-1713  COG1340
pfam138511590-1759  GAS
pfam121281430-1755  DUF3584
pfam097301566-1736  BicD
PTZ004401440-1761  PTZ00440
smart007871243-1327  Spc7
pfam057011578-1747  WEMBL
TIGR042111568-1644  SH3_and_anchor
COG50741568-1679  COG5074
pfam061601429-1726  EzrA
PRK047781242-1547  PRK04778


Ontology Information


   
HPRD ID18003
Molecular ClassUnclassified
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO