CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
8869106	1996	Cell line : - Source : - Sample Type : CRC tumor and adjecent normal tissue No. of Sample : 18 Stage : -	RNase protection assay	Up-regulation	-	LCK message is strongly expressed in some colorectal cancers.

Gene Details

NC_000001.10 (32716840..32751766)
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Gene Type	protein coding
Gene Family	SH2 domain containing
Description	This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
Chromosome	1
Location	1p34.3
Start	32716840
End	32751766
Strand	+
Gene Sequence	Download   Select all
Length	34927
OMIM ID	153390
HGNC ID	HGNC:6524
Unigene ID	Hs.470627
Ensembl ID	ENSG00000182866
PharmGKB ID	PA30307

mRNA Information

mRNA ID	XM_011541453.1
Exon	join(1..133,23087..23196,23499..23845,24083..24181, 24331..24434,24676..24825,25369..25548,28433..28509, 28603..28756,28841..28972,34276..34932)
mRNA Sequence	Download   Select all
Length	2143

CDS Information

   

Location	139..1689
CDS Sequence	Download   Select all
CCDS ID	CCDS359.1

Protein Information

      

Protein ID	XP_011539755.1
Protein Name	LCK proto-oncogene, Src family tyrosine kinase
Molecular Wt. (Da)	36558
Protein Sequence	Download   Select all
Length	516
Uniprot ID	P15884
Ensembl Protein ID	ENSP00000346440

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
G	Myristoylation	2
C	Palmitoylation	3
C	Palmitoylation	5
Y	Phosphorylation	505
Y	Phosphorylation	394
Y	Dephosphorylation	394
Y	Dephosphorylation	505
Y	Phosphorylation	394
Y	Dephosphorylation	394
S	Phosphorylation	59
S	Phosphorylation	42
Y	Phosphorylation	192
S	Phosphorylation	42
S	Phosphorylation	59
Y	Dephosphorylation	394
Y	Dephosphorylation	394
Y	Phosphorylation	394
Y	Phosphorylation	505
Y	Phosphorylation	394
Y	Phosphorylation	505
Y	Phosphorylation	192;-
K	Acetylation	179
K	Acetylation	179
Y	Phosphorylation	393
Y	Phosphorylation	393
S	Phosphorylation	133
S	Phosphorylation	133

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
52	ACP1	8881	NP_004291.1	in vitro;in vivo	9038134
355	FAS	609	NP_000034.1	in vivo	8864141
356	FASLG	610	NP_000630.1	in vivo	11741599
558	AXL	171	NP_068713.2	in vivo	9178760
916	CD3E	8923	NP_000724.1	in vitro;in vivo	11855827
919	CD247	1729	NP_932170.1	in vivo	9047237
921	CD5	1078	NP_055022.2	in vitro;in vivo	75   130   451   129   834   400   000   000
952	CD38	116	NP_001766.2	in vitro;in vivo	10636863
960	CD44	115	NP_000601.3	in vitro;in vivo	8576267
962	CD48	177	NP_001769.2	in vitro	120   077   898   104   794
974	CD79B	922	NP_001035022.1	in vitro	8077654
1493	CTLA4	474	NP_005205.2	in vitro;in vivo	97   127   169   973   379
1604	CD55	500	NP_001108224.1	in vivo	1385527
1796	DOK1	4228	NP_001372.1	in vivo	10799545
2099	ESR1	589	NP_000116.2	in vitro;in vivo	7539106
2100	ESR2	3390	NP_001428.1	in vitro	12415108
3560	IL2RB	896	NP_000869.1	in vitro	204   785   910   214   954
3702	ITK	1746	NP_005537.3	in vitro;in vivo	931   216   215   144   186
3804	KIR2DL3	10383	NP_056952.2	in vitro	9751747
3937	LCP2	3362	NP_005556.1	in vitro;in vivo	870   266   216   354   835
4068	SH2D1A	2390	NP_002342.1	in vitro;yeast 2-hybrid	15096483
4582	MUC1	1152	P15941	in vitro;in vivo	14766232
4792	NFKBIA	1235	NP_065390.1	in vitro;in vivo	8   797   825   124   297   430   000   000
5295	PIK3R1	1381	NP_852664.1	in vitro;in vivo	750   417   494   615   888   000   000
5336	PLCG2	2570	AAH11772.1	in vitro	12   181   444   768   205   900   000   000
5580	PRKCD	1501	NP_006245.2	in vitro	11381116
5588	PRKCQ	2710	NP_006248.1	in vitro;in vivo	10652356
5747	PTK2	2859	NP_005598.3	in vitro;in vivo	9257837
5921	RASA1	745	NP_002881.1	in vitro;in vivo	1850098
6452	SH3BP2	3657	NP_003014.3	in vitro;in vivo	15751964
6464	SHC1	2780	NP_001123512.1	in vivo	122   377   751   107   571   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000
6772	STAT1	2777	NP_009330.1	in vitro;in vivo	765   766   011   294   897   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000
6774	STAT3	26	NP_644805.1	in vivo	10825200
6776	STAT5A	3301	NP_003143.2	in vitro	10825200
7409	VAV1	1284	NP_005419.2	in vivo	10669745
7430	EZR	475	NP_003370.2	in vitro;in vivo	138   207   012   560   083
7535	ZAP70	1495	NP_001070.2	in vitro;in vivo	1   031   884   379   619   360   000   000   000   000   000   000   000
9846	GAB2	5866	NP_036428.1	in vivo	11572860
10019	SH2B3	5480	NP_005466.1	in vitro;in vivo	107   998   799   169   414
10750	GRAP	5062	NP_006604.1	in vitro;in vivo	8995379
27040	LAT	3832	NP_001014989.2	in vitro;in vivo	1   235   971   512   186   560
27071	DAPP1	5773	NP_055210.2	in vitro;in vivo	10880360
50619	DEF6	10869	NP_071330.3	in vitro	12923183
54900	LAX1	8312	NP_060243.2	in vivo	12359715
54923	LIME1	7904	NP_060276.2	in vivo	14610044
80306	MED28	14381	NP_079481.2	in vitro;in vivo	16899217

Pathway Information

                                    

Pathway Name	Pathway ID
HTLV-I infection	hsa05166
Natural killer cell mediated cytotoxicity	hsa04650
NF-kappa B signaling pathway	hsa04064
Osteoclast differentiation	hsa04380
Primary immunodeficiency	hsa05340
T cell receptor signaling pathway	hsa04660

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd05067	237-500	PTKc_Lck_Blk
cl21453	237-500	PKc_like superfamily
cd10362	123-223	SH2_Src_Lck
cl15255	123-223	SH2 superfamily
cd12005	65-118	SH3_Lck
cl17036	65-118	SH3 superfamily
cd05034	249-495	PTKc_Src_like
cd05072	238-506	PTKc_Lyn
cd05073	233-497	PTKc_Hck
cd05068	236-499	PTKc_Frk_like
cd14203	250-496	PTKc_Src_Fyn_like
cd05069	235-507	PTKc_Yes
cd05070	235-507	PTKc_Fyn
cd05071	235-507	PTKc_Src
cd00192	249-495	PTKc
cd05148	238-497	PTKc_Srm_Brk
cd05059	245-494	PTKc_Tec_like
cd05052	238-498	PTKc_Abl
cd05039	238-495	PTKc_Csk_like
cd05112	241-490	PTKc_Itk
cd05041	249-494	PTKc_Fes_like
cd05033	245-497	PTKc_EphR
cd05060	249-496	PTKc_Syk_like
cd05113	240-495	PTKc_Btk_Bmx
cd05114	241-495	PTKc_Tec_Rlk
cd05032	238-496	PTKc_InsR_like
cd05044	251-496	PTKc_c-ros
cd05053	237-496	PTKc_FGFR
cd05040	249-496	PTKc_Ack_like
cd05082	238-496	PTKc_Csk
cd13999	251-488	STKc_MAP3K-like
cd05083	238-495	PTKc_Chk
cd05036	239-490	PTKc_ALK_LTK
cd05066	248-495	PTKc_EphR_A
cd05056	238-496	PTKc_FAK
cd05085	249-494	PTKc_Fer
cd05084	249-494	PTKc_Fes
cd05063	251-495	PTKc_EphR_A2
cd05065	245-497	PTKc_EphR_B
cd05055	234-496	PTKc_PDGFR
cd05051	239-490	PTKc_DDR
cd05045	245-495	PTKc_RET
cd05049	239-494	PTKc_Trk
cd05099	237-505	PTKc_FGFR4
cd05057	240-497	PTKc_EGFR_like
cd05048	239-487	PTKc_Ror
cd05116	251-498	PTKc_Syk
cd05050	239-495	PTKc_Musk
cd05038	240-490	PTKc_Jak_rpt2
cd05061	238-496	PTKc_InsR
cd05115	242-487	PTKc_Zap-70
cd05064	239-494	PTKc_EphR_A10
cd05098	229-504	PTKc_FGFR1
cd05046	240-496	PTK_CCK4
cd09933	123-223	SH2_Src_family
cd05054	237-496	PTKc_VEGFR
cd05106	226-495	PTKc_CSF-1R
cd05035	245-496	PTKc_TAM
cd05062	238-496	PTKc_IGF-1R
cd05092	240-495	PTKc_TrkA
cd05101	229-504	PTKc_FGFR2
cd05100	237-501	PTKc_FGFR3
cd05058	251-500	PTKc_Met_Ron
cd05075	245-495	PTKc_Axl
cd14204	240-495	PTKc_Mer
cd05047	251-487	PTKc_Tie
cd05095	239-496	PTKc_DDR2
cd05089	243-487	PTKc_Tie1
cd10363	123-224	SH2_Src_HCK
cd00180	251-494	PKc
cd05091	239-494	PTKc_Ror2
cd05097	239-494	PTKc_DDR_like
cd05079	245-490	PTKc_Jak1_rpt2
cd05102	237-498	PTKc_VEGFR3
cd10364	123-223	SH2_Src_Lyn
cd05074	240-495	PTKc_Tyro3
cd05090	239-487	PTKc_Ror1
cd05105	229-498	PTKc_PDGFR_alpha
cd05107	234-499	PTKc_PDGFR_beta
cd05043	240-500	PTK_Ryk
cd14014	246-486	STKc_PknB_like
cd05108	242-490	PTKc_EGFR
cd05096	239-494	PTKc_DDR1
cd05109	242-497	PTKc_HER2
cd05093	240-501	PTKc_TrkB
cd14205	245-496	PTKc_Jak2_rpt2
cd05103	237-501	PTKc_VEGFR2
cd14207	237-497	PTKc_VEGFR1
cd05080	245-497	PTKc_Tyk2_rpt2
cd05094	240-501	PTKc_TrkC
cd05110	242-490	PTKc_HER4
cd10371	123-223	SH2_Src_Blk
cd05104	226-495	PTKc_Kit
cd05081	245-495	PTKc_Jak3_rpt2
cd06606	246-486	STKc_MAPKKK
cd05088	245-487	PTKc_Tie2
cd05111	245-492	PTK_HER3
cd14061	251-487	STKc_MLK
cd14059	251-495	STKc_MAP3K12_13
cd10367	123-223	SH2_Src_Fgr
cd06627	247-486	STKc_Cdc7_like
cd13978	251-487	STKc_RIP
cd10370	123-223	SH2_Src_Src42
cd14151	236-497	STKc_B-Raf
cd14062	251-495	STKc_Raf
cd10418	123-223	SH2_Src_Fyn_isoform_a_like
cd10368	125-223	SH2_Src_Fyn
cd10369	123-223	SH2_Src_Frk
cd14146	251-487	STKc_MLK4
cd14066	251-497	STKc_IRAK
cd14147	245-495	STKc_MLK3
cd14150	245-495	STKc_A-Raf
cd14060	252-495	STKc_MLTK
cd14148	251-496	STKc_MLK2
cd14009	251-498	STKc_ATG1_ULK_like
cd14145	239-487	STKc_MLK1
cd14149	238-495	STKc_C-Raf
cd10365	123-221	SH2_Src_Src
cd10344	112-219	SH2_SLAP
cd10419	127-221	SH2_Src_Fyn_isoform_b_like
cd05122	246-486	PKc_STE
cd10366	123-221	SH2_Src_Yes
cd14058	251-499	STKc_TAK1
cd14065	251-487	PKc_LIMK_like
cd14027	251-487	STKc_RIP1
cd13979	243-488	STKc_Mos
cd13992	286-487	PK_GC
pfam00017	127-209	SH2
cd14003	246-486	STKc_AMPK-like
cd14158	250-496	STKc_IRAK4
cd14042	261-498	PK_GC-A_B
cd08215	246-486	STKc_Nek
cd07840	248-498	STKc_CDK9_like
cd14008	251-486	STKc_LKB1_CaMKK
cd14154	251-495	STKc_LIMK
cd06632	251-490	STKc_MEKK1_plant
cd14063	245-495	PK_KSR
cd06625	246-486	STKc_MEKK3_like
cd05087	248-486	PTKc_Aatyk1
cd05117	246-456	STKc_CAMK
cd05118	246-486	STKc_CMGC
cd06628	251-490	STKc_Byr2_like
cd14056	249-491	STKc_TGFbR_I
smart00252	125-215	SH2
cd13996	242-486	STKc_EIF2AK
cd14221	251-497	STKc_LIMK1
cd06614	245-490	STKc_PAK
cd07829	248-443	STKc_CDK_like
cd14664	251-496	STK_BAK1_like
cd06623	245-486	PKc_MAPKK_plant_like
cd07830	246-486	STKc_MAK_like
cd05037	249-496	PTK_Jak_rpt1
cd05042	249-486	PTKc_Aatyk
cd14156	251-496	PKc_LIMK_like_unk
cd14064	251-496	PKc_TNNI3K
cd06609	245-490	STKc_MST3_like
cd08529	247-492	STKc_FA2-like
cd14222	251-500	STKc_LIMK2
cd14025	249-495	STKc_RIP4_like
cd14000	251-496	STKc_LRRK
cd14206	248-490	PTKc_Aatyk3
cd13997	248-490	PKc_Wee1_like
cd08222	247-486	STKc_Nek11
cd14007	251-488	STKc_Aurora
cd06610	246-490	STKc_OSR1_SPAK
cd14121	249-499	STKc_ULK3
cd14081	246-488	STKc_BRSK1_2
cd14045	262-494	PK_GC_unk
cd14120	251-499	STKc_ULK1_2-like
cd06612	241-486	STKc_MST1_2
cd14155	251-495	PKc_TESK
cd14098	247-486	STKc_Rad53_Cds1
cd08530	246-490	STKc_CNK2-like
cd08217	246-486	STKc_Nek2
cd06642	241-486	STKc_STK25
cd06629	249-492	STKc_Bck1_like
cd06605	245-490	PKc_MAPKK
cd06641	241-486	STKc_MST3
cd07866	246-445	STKc_BUR1
cd14043	314-488	PK_GC-2D
cd14202	251-498	STKc_ULK1
cd14075	251-492	STKc_NIM1
cd08225	247-486	STKc_Nek5
cd06917	249-490	STKc_NAK1_like
cd14144	251-486	STKc_BMPR1
cd06626	250-486	STKc_MEKK4
cd06621	248-486	PKc_Pek1_like
cd14220	250-486	STKc_BMPR1a
cd13998	249-486	STKc_TGFbR-like
cd14162	251-441	STKc_TSSK4-like
cd14190	249-456	STKc_MLCK2
cd05086	248-486	PTKc_Aatyk2
cd13983	245-486	STKc_WNK
cd14053	254-435	STKc_ACVR2
cd05123	251-484	STKc_AGC
cd14072	246-459	STKc_MARK
cd14006	251-456	STKc_MLCK-like
cd06640	241-486	STKc_MST4
cd12004	65-120	SH3_Lyn
cd14012	293-486	PK_eIF2AK_GCN2_rpt1
cd05078	245-497	PTK_Jak2_rpt1
cd14052	247-456	PTKc_Wee1_fungi
cd14073	247-492	STKc_NUAK
cd14119	251-492	STKc_LKB1
cd06653	246-435	STKc_MEKK3_like_u1
cd14201	251-488	STKc_ULK2
cd07841	248-445	STKc_CDK7
cd14192	248-453	STKc_MLCK3
cd14057	250-495	PK_ILK
cd08229	223-493	STKc_Nek7
cd14084	251-430	STKc_Chk2
cd14046	248-486	STKc_EIF2AK4_GCN2_rpt2
cd05076	284-497	PTK_Tyk2_rpt1
cd14080	247-441	STKc_TSSK-like
cd09935	123-223	SH2_ABL
cd14068	251-492	STKc_LRRK2
cd12009	66-118	SH3_Blk
cd05581	245-498	STKc_PDK1
cd14188	288-498	STKc_PLK2
cd14219	243-486	STKc_BMPR1b
cd14047	242-494	STKc_EIF2AK2_PKR
cd00173	126-209	SH2
cd13985	247-496	STKc_GAK_like
cd06652	246-435	STKc_MEKK2
cd13982	249-486	STKc_IRE1
cd10360	126-209	SH2_Srm
cd14142	245-486	STKc_ACVR1_ALK1
cd07877	238-455	STKc_p38alpha
cd14071	248-448	STKc_SIK
cd14103	251-456	STKc_MLCK
cd14131	249-490	PKc_Mps1
cd11845	65-115	SH3_Src_like
cd14078	247-430	STKc_MELK
cd07836	246-448	STKc_Pho85
cd14105	247-456	STKc_DAPK
cd07834	246-446	STKc_MAPK
cd07870	248-455	STKc_PFTAIRE2
cd07845	250-451	STKc_CDK10
cd14026	251-487	STKc_RIP2
cd14099	251-498	STKc_PLK
cd14143	249-486	STKc_TGFbR1_ACVR1b_ACVR1c
cd13993	245-491	STKc_Pat1_like
cd14050	248-490	PKc_Myt1
cd08224	246-493	STKc_Nek6_7
cd14044	288-499	PK_GC-C
cd14161	242-488	STKc_NUAK2
cd14079	246-430	STKc_AMPK_alpha
cd06611	241-490	STKc_SLK_like
cd07833	246-490	STKc_CDKL
cd14193	249-453	STKc_MLCK4
cd08223	247-486	STKc_Nek4
cd08218	248-495	STKc_Nek1
cd14663	246-441	STKc_SnRK3
cd06651	251-436	STKc_MEKK3
cd07869	243-455	STKc_PFTAIRE1
cd07871	243-509	STKc_PCTAIRE3
cd14106	289-488	STKc_DRAK
cd06622	245-490	PKc_PBS2_like
cd14054	249-448	STKc_BMPR2_AMHR2
cd06624	251-486	STKc_ASK
cd05077	284-496	PTK_Jak1_rpt1
cd07878	238-455	STKc_p38beta
cd07844	244-448	STKc_PCTAIRE_like
cd14164	246-486	STKc_TSSK6-like
cd09941	123-213	SH2_Grb2_like
cd14196	249-453	STKc_DAPK2
cd08528	247-485	STKc_Nek10
cd07864	247-435	STKc_CDK12
cd06631	249-490	STKc_YSK4
cd06636	241-433	STKc_MAP4K4_6_N
cd07838	246-433	STKc_CDK4_6_like
cd09937	126-223	SH2_csk_like
cd07860	248-463	STKc_CDK2_3
cd13987	251-441	STKc_SBK1
cd14152	245-495	STKc_KSR1
cd06659	241-441	STKc_PAK6
cd06617	245-447	PKc_MKK3_6
cd08219	251-486	STKc_Nek3
cd08228	245-493	STKc_Nek6
cd14159	251-440	STKc_IRAK1
cd14069	246-492	STKc_Chk1
cd14137	244-446	STKc_GSK3
cd13990	251-505	STKc_TLK
cd06630	251-486	STKc_MEKK1
cd05580	245-433	STKc_PKA_like
cd06620	243-486	PKc_Byr1_like
cd14194	249-453	STKc_DAPK1
cd14153	245-495	PK_KSR2
cd07843	243-435	STKc_CDC2L1
cd07846	243-486	STKc_CDKL2_3
cd14195	249-453	STKc_DAPK3
cd06637	241-433	STKc_TNIK
cd07879	238-435	STKc_p38delta
cd07851	238-443	STKc_p38
cd07873	243-448	STKc_PCTAIRE1
cd06648	241-441	STKc_PAK_II
cd09938	126-224	SH2_N-SH2_Zap70_Syk_like
cd14191	249-453	STKc_MLCK1
cd14096	243-430	STKc_RCK1-like
cd05611	254-456	STKc_Rim15_like
cd14114	247-455	STKc_Twitchin_like
cd14186	243-498	STKc_PLK4
cd07832	246-433	STKc_CCRK
cd14198	299-486	STKc_DRAK2
cd14074	247-441	STKc_SNRK
cd06613	246-432	STKc_MAP4K3_like
cd14208	249-496	PTK_Jak3_rpt1
cd06643	235-433	STKc_SLK
cd06647	241-441	STKc_PAK_I
cd13975	246-499	PKc_Dusty
cd14185	269-486	STKc_DCKL3
cd14055	249-486	STKc_TGFbR2_like
cd07861	248-435	STKc_CDK1_euk
cd08220	251-488	STKc_Nek8
cd07872	243-509	STKc_PCTAIRE2
cd14165	251-441	STKc_TSSK1_2-like
cd07880	238-443	STKc_p38gamma
cd14067	285-485	STKc_LRRK1
cd06633	241-486	STKc_TAO3
cd05578	252-446	STKc_Yank1
cd07849	251-443	STKc_ERK1_2_like
cd07839	248-443	STKc_CDK5
cd09931	127-210	SH2_C-SH2_SHP_like
cd14037	242-486	STKc_NAK_like
cd13994	251-498	STKc_HAL4_like
cd14133	246-495	PKc_DYRK_like
cd14197	299-486	STKc_DRAK1
cd06646	241-433	STKc_MAP4K5
cd14010	247-452	STKc_ULK4
cd07856	251-443	STKc_Sty1_Hog1
cd06638	236-486	STKc_myosinIIIA_N
cd14189	251-498	STKc_PLK3
cd14002	243-441	STKc_STK36
cd06607	251-486	STKc_TAO
cd05616	251-453	STKc_cPKC_beta
cd07854	269-451	STKc_MAPK4_6
cd07835	248-443	STKc_CDK1_CdkB_like
cd06608	241-428	STKc_myosinIII_N_like
cd09934	120-223	SH2_Tec_family
cd14116	233-495	STKc_Aurora-A
cd05619	243-462	STKc_nPKC_theta
cd05572	251-484	STKc_cGK
cd06644	241-486	STKc_STK10
cd07865	244-484	STKc_CDK9
cd05582	251-484	STKc_RSK_N
cd07852	246-443	STKc_MAPK15-like
cd06657	241-475	STKc_PAK4
cd14095	288-430	STKc_DCKL
cd06616	238-490	PKc_MKK4
cd14005	251-487	STKc_PIM
cd14076	251-460	STKc_Kin4
cd06655	241-457	STKc_PAK2
cd06619	243-486	PKc_MKK5
cd06618	238-490	PKc_MKK7
cd14077	247-441	STKc_Kin1_2
cd05579	269-452	STKc_MAST_like
cd10358	125-228	SH2_PTK6_Brk
cd08221	248-490	STKc_Nek9
cd14033	245-472	STKc_WNK4
cd06650	239-442	PKc_MEK1
cd06658	241-475	STKc_PAK5
cd14017	246-495	STKc_TTBK
cd05607	251-484	STKc_GRK7
cd06654	241-457	STKc_PAK1
cd05615	251-453	STKc_cPKC_alpha
cd14039	251-434	STKc_IKK_alpha
cd06656	241-457	STKc_PAK3
cd14048	248-482	STKc_EIF2AK3_PERK
cd05570	251-484	STKc_PKC
cd07862	248-433	STKc_CDK6
cd06645	241-490	STKc_MAP4K3
cd07863	248-433	STKc_CDK4
cd14097	250-456	STKc_STK33
cd05589	246-484	STKc_PKN
cd05620	251-453	STKc_nPKC_delta
cd14104	249-480	STKc_Titin
cd14101	251-488	STKc_PIM2
cd14038	250-451	STKc_IKK_beta
cd14100	347-488	STKc_PIM1
cd10398	121-223	SH2_Tec_Txk
cd05592	251-443	STKc_nPKC_theta_like
cd12006	65-117	SH3_Fyn_Yrk
cd07847	286-443	STKc_CDKL1_4
cd13988	251-460	STKc_TBK1
cd10354	126-209	SH2_Cterm_RasGAP
cd14001	288-496	PKc_TOPK
cd06615	312-442	PKc_MEK
cd09943	125-212	SH2_Nck_family
cd06634	241-490	STKc_TAO2
cd10347	127-209	SH2_Nterm_shark_like
cd10348	127-216	SH2_Cterm_shark_like
cd14004	248-490	STKc_PASK
cd06649	239-442	PKc_MEK2
cd14166	242-457	STKc_CaMKI_gamma
cd14132	233-434	STKc_CK2_alpha
pfam00018	67-112	SH3_1
cd06635	239-490	STKc_TAO1
cd13986	288-496	STKc_16
cd14093	283-430	STKc_PhKG
cd14113	234-486	STKc_Trio_C
cd14184	288-446	STKc_DCKL2
cd07857	246-440	STKc_MPK1
cd14160	251-439	PK_IRAK3
cd14102	346-488	STKc_PIM3
cd05632	242-443	STKc_GRK5
cd14200	246-486	STKc_CaMKK1
cd13989	251-447	STKc_IKK
smart00326	66-117	SH3
cd14031	245-502	STKc_WNK3
cd14112	241-488	STKc_Unc-89_rpt2
cd14118	288-486	STKc_CAMKK
cd14030	245-484	STKc_WNK1
cd10340	127-210	SH2_N-SH2_SHP_like
cd14109	283-456	PK_Unc-89_rpt1
cd11768	65-118	SH3_Tec_like
cd12007	67-120	SH3_Yes
cd10402	123-224	SH2_C-SH2_Zap70
cd14092	288-441	STKc_MSK_C
cd05631	251-441	STKc_GRK4
cd14011	257-485	PK_SCY1_like
cd12008	67-117	SH3_Src
cd06639	241-490	STKc_myosinIIIB_N
cd14049	248-486	STKc_EIF2AK1_HRI
cd14187	269-500	STKc_PLK1
cd14032	245-450	STKc_WNK2_like
cd05603	251-441	STKc_SGK2
cd14091	291-455	STKc_RSK_C
cd14163	246-456	STKc_TSSK3-like
cd05595	251-484	STKc_PKB_beta
cd10401	123-225	SH2_C-SH2_Syk_like
cd14111	241-441	STKc_SPEG_rpt2
cd07859	246-443	STKc_TDY_MAPK
cd05605	244-441	STKc_GRK4_like
cd10397	120-223	SH2_Tec_Btk
cd07858	286-443	STKc_TEY_MAPK
cd12011	67-118	SH3_SLAP2
cd10341	125-213	SH2_N-SH2_PLC_gamma_like
cd14082	249-430	STKc_PKD
cd07850	251-443	STKc_JNK
cd05630	244-441	STKc_GRK6
cd00174	66-115	SH3
cd14140	254-438	STKc_ACVR2b
cd11848	67-118	SH3_SLAP-like
cd05577	251-484	STKc_GRK
cd14135	246-450	STKc_PRP4
cd14175	249-464	STKc_RSK1_C
cd07842	252-438	STKc_CDK8_like
cd14108	286-457	STKc_SPEG_rpt1
cd14107	249-509	STKc_obscurin_rpt1
cd14183	288-448	STKc_DCKL1
cd14019	246-441	STKc_Cdc7
cd10355	122-211	SH2_DAPP1_BAM32_like
cd05602	251-480	STKc_SGK1
cd05573	243-484	STKc_ROCK_NDR_like
cd09944	125-225	SH2_Grb7_family
cd14086	246-430	STKc_CaMKII
cd05612	245-456	STKc_PRKX_like
cd05584	251-484	STKc_p70S6K
cd14169	247-484	STKc_CaMKI_beta
cd13995	254-486	STKc_MAP3K8
cd05601	251-445	STKc_CRIK
cd10399	121-226	SH2_Tec_Bmx
cd05590	251-451	STKc_nPKC_eta
cd09930	127-223	SH2_cSH2_p85_like
cd05613	245-441	STKc_MSK1_N
cd05604	245-463	STKc_SGK3
cd14179	288-441	STKc_MSK1_C
cd14141	312-435	STKc_ACVR2a
cd07831	246-435	STKc_MOK
cd14016	246-387	STKc_CK1
cd14051	248-486	PTKc_Wee1
cd14176	291-456	STKc_RSK2_C
cd09932	123-211	SH2_C-SH2_PLC_gamma_like
cd14138	248-486	PTKc_Wee1a
cd05587	251-453	STKc_cPKC
cd07853	251-439	STKc_NLK
cd14199	246-441	STKc_CaMKK2
cd10408	126-212	SH2_Nck1
cd07855	243-443	STKc_ERK5
cd14070	250-485	STKc_HUNK
cd14036	268-485	STKc_GAK
cd14094	288-486	STKc_CASK
cd14177	291-450	STKc_RSK4_C
cd14089	249-488	STKc_MAPKAPK
cd14129	246-504	STKc_TTBK2
cd10409	127-212	SH2_Nck2
cd08216	270-486	PK_STRAD
pfam07714	245-494	Pkinase_Tyr
smart00221	245-494	STYKc
smart00219	245-494	TyrKc
smart00220	246-488	S_TKc
pfam00069	245-490	Pkinase
COG0515	246-467	SPS1
PTZ00024	251-470	PTZ00024
PLN00009	248-443	PLN00009
PTZ00266	236-481	PTZ00266
PHA03209	246-442	PHA03209
PTZ00263	245-434	PTZ00263
PLN00034	241-442	PLN00034
PTZ00267	347-486	PTZ00267
PRK13184	247-441	pknD
PHA02988	262-486	PHA02988
PTZ00426	225-434	PTZ00426
TIGR03903	285-484	TOMM_kin_cyc
COG4248	341-444	YegI

Ontology Information

   

HPRD ID	800
Molecular Class	Tyrosine kinase
Molecular Function	Transcription factor activity (GO:0003700)
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)

SNP Information

View SNP Geneview Report