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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
LGALS9 3965 Lectin, galactoside-binding, soluble, 9 (galectin 9)  17HUAT; LGALS9A 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20089989   2010Cell line : -

Source : VU University Medical Center, Amsterdam, The Netherlands.

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : -

Biochemical isolation to nano-LC-MS/MS analysis Down-regulation-This genes are differenitially expressed between colorectal adenoma and Colorectal cancer tissue.


Gene Details



Chromosome: 17; NC_000017.10 (25958174..25976586)

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Gene Type protein coding
Gene Family Lectins, galactoside-binding
Description The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]  
Chromosome 17
Location 17q11.2
Start 27631148  
End 27649560  
Strand +  
Gene Sequence

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Length 18413  
OMIM ID 601879   
HGNC ID HGNC:6570   
Unigene ID Hs.81337    
Ensembl ID ENSG00000168961   
PharmGKB ID PA30347   

mRNA Information


mRNA ID NM_009587.2
Exon join(1..157,7116..7207,9425..9626,11091..11201, 12378..12473,14167..14202,14714..14764,15400..15441, 15883..15971,16123..16285,17689..18413)  
mRNA Sequence

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Length 1835  



CDS Information


   
Location join(119..157,7116..7207,9425..9626,11091..11201, 12378..12473,14167..14202,14714..14764,15400..15441, 15883..15971,16123..16285,17689..17835)
CDS Sequence

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CCDS ID CCDS11222.1



Protein Information


      
Protein IDNP_033665.1
Protein NameLectin, galactoside-binding, soluble, 9 (galectin 9)
Molecular Wt. (Da)39387
Protein Sequence

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Length 355  
Uniprot IDP22223
Ensembl Protein ID ENSP00000264012  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0007016-146  GLECT
cl0007116-146  GLECT superfamily
cd00070226-354  GLECT
cl00071226-354  GLECT superfamily
pfam0033716-147  Gal-bind_lectin
smart0090822-146  Gal-bind_lectin
smart0027617-147  GLECT
smart00908233-354  Gal-bind_lectin
pfam00337226-354  Gal-bind_lectin
smart00276227-354  GLECT
pfam15449154-224  Retinal


Ontology Information


   
HPRD ID8960
Molecular ClassChemokine
Molecular FunctionCell adhesion molecule activity (GO:0005194)
Biological ProcessCell growth and/or maintenance (GO:0008151)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO