Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| LRRC28 | 123355 | leucine rich repeat containing 28 | 15 | MGC24976, FLJ34269, FLJ45242 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23045723 | 2012 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 17 CRC and 59 normal tissues Stage : - | Microarray | Down-regulation | - | SHOC2 and LRRC28 genes involved in RAS-mediated signaling, which hinders nutrient deprivation-induced autophagy, might be a possible link between the negative control of autophagy and tumorigenesis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 15 |
| Location | 15q26.3 |
| Start | 99791567 |
| End | 99930934 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 139368 |
| OMIM ID | - |
| HGNC ID | HGNC:28355 |
| Unigene ID | Hs.578684 |
| Ensembl ID | ENSG00000168904 |
| PharmGKB ID | PA134864287 |
Protein Information
| Protein ID | NP_001271329.1 |
|---|---|
| Protein Name | leucine rich repeat containing 28 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 367 |
| Uniprot ID | Q5VY80 |
| Ensembl Protein ID | ENSP00000286380 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam12799 | 65-101 | LRR_4 |
| cl19302 | 65-101 | LRR_4 superfamily |
| pfam13855 | 43-100 | LRR_8 |
| PRK15370 | 46-306 | PRK15370 |
| COG4886 | 3-221 | LRR |
| PRK15370 | 3-223 | PRK15370 |
| PRK15370 | 11-176 | PRK15370 |
| PLN00113 | 39-225 | PLN00113 |
| PLN00113 | 12-221 | PLN00113 |
| PRK15387 | 43-220 | PRK15387 |
| PRK15387 | 43-193 | PRK15387 |
| pfam13855 | 18-77 | LRR_8 |
| PLN03150 | 125-200 | PLN03150 |
| PRK15387 | 123-221 | PRK15387 |
| PLN03150 | 79-169 | PLN03150 |
| PLN00113 | 43-221 | PLN00113 |
| COG4886 | 40-175 | LRR |
| pfam14580 | 25-78 | LRR_9 |
| pfam13855 | 120-169 | LRR_8 |
Ontology Information
| HPRD ID | 10475 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Auxiliary transport protein activity (GO:0015457) |
| Biological Process | Transport (GO:0006810) |
Drug Information
No matching records could be found.