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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
LYAR 55646 Ly1 antibody reactive  4ZC2HC2, ZLYAR 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
26413750   2015Cell line : -

Source : Shanghai Biochip Co., Ltd., Shanghai, China.

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : -

Microarray analysis,Immunohistochemistry ,Chromatoimmunoprecepetation, Up-regulation-LYAR may promote tumor cell migration and invasion by upregulating galectin-1 gene expression in CRC.


Gene Details



NC_000004.11 (4269428..4291896, complement)

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Gene Type protein coding
Gene Family Zinc fingers, C2HC-type containing
Description -  
Chromosome 4
Location 4p16.3
Start 4269428  
End 4291896  
Strand -  
Gene Sequence

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Length 22469  
OMIM ID -   
HGNC ID HGNC:26021   
Unigene ID Hs.425427   
Ensembl ID ENSG00000145220   
PharmGKB ID PA162394697   

mRNA Information


mRNA ID ?NM_001145725.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS3374.1



Protein Information


      
Protein IDNP_001139197.1
Protein NameLy1 antibody reactive
Molecular Wt. (Da)0
Protein Sequence

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Length 379  
Uniprot IDQ9H1E3
Ensembl Protein ID ENSP00000356110  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation258
SPhosphorylation244
SPhosphorylation276
SPhosphorylation260
SPhosphorylation128
SPhosphorylation215
SPhosphorylation282

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                              
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
7704ZBTB1611762NP_005997.2yeast 2-hybrid16169070   
11244ZHX110379NP_009153.3yeast 2-hybrid16169070   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam0879031-58  zf-LYAR
cl0741131-58  zf-LYAR superfamily


Ontology Information


   
HPRD ID12297
Molecular ClassTranscription regulatory protein
Molecular FunctionMethyltransferase activity (GO:0008168)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO