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General Information
- Evidence
- Gene
- mRNA
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- Protein
- PTM
- Enzyme
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20825414 | 2010 | Cell line : - Source : Department of Surgery, Osaka University (Osaka, Japan) and the Department of Surgery and Molecular Oncology, Kyushu University (Beppu, Japan) Sample Type : CRC tumor No. of Sample : 240 Stage : TNM Stage I-IV | Immunohistochemistry,real time RT-PCR | Up-regulation | - | Expression of the C4.4A protein at the invasive front acts as a novel prognostic marker in colorectal cancer, possibly through invasion-related mechanisms. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 19 |
| Location | 19q13.31 |
| Start | 43964946 |
| End | 43969831 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 4886 |
| OMIM ID | 609484 |
| HGNC ID | HGNC:24880 |
| Unigene ID | Hs.631594 |
| Ensembl ID | - |
| PharmGKB ID | PA142671490 |
Protein Information
| Protein ID | NP_055215.2 |
|---|---|
| Protein Name | LY6/PLAUR domain containing 3 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 346 |
| Uniprot ID | Q96FW1 |
| Ensembl Protein ID | ENSP00000402551 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| F | Proteolytic Cleavage | 231 |
| R | Proteolytic Cleavage | 234 |
| Y | Proteolytic Cleavage | 230 |
| N | Glycosylation | 163 |
| S | Phosphorylation | 289 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00117 | 31-116 | LU |
| cl10471 | 31-116 | LU superfamily |
| cd00117 | 139-224 | LU |
| cl10471 | 139-224 | LU superfamily |
| pfam00021 | 140-222 | UPAR_LY6 |
| smart00134 | 31-118 | LU |
Ontology Information
| HPRD ID | 10064 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.