Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| MAD2L2 | 10459 | MAD2 mitotic arrest deficient-like 2 (yeast) | 1 | MAD2B, REV7, POLZ2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 17044027 | 2007 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 118 Stage : - | real-time RT- PCR | Up-regulation | - | Overexpression of MAD2L2 correlates with bad prognosis in colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | DNA polymerases |
| Description | The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008] | Chromosome | 1 |
| Location | 1p36 |
| Start | 11734537 |
| End | 11751678 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 17142 |
| OMIM ID | 604094 |
| HGNC ID | HGNC:6764 |
| Unigene ID | Hs.19400 |
| Ensembl ID | ENSG00000116670 |
| PharmGKB ID | PA398 |
Protein Information
| Protein ID | NP_001120797.1 |
|---|---|
| Protein Name | MAD2 mitotic arrest deficient-like 2 (yeast) |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 211 |
| Uniprot ID | Q9NRM7 |
| Ensembl Protein ID | ENSP00000372035 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 991 | CDC20 | 4686 | NP_001246.2 | in vitro | 11459826 |
| 999 | CDH1 | 1885 | BAA88957.1 | in vitro | 11459826 |
| 5980 | REV3L | 4145 | O60673 | in vitro;in vivo;yeast 2-hybrid | 1 148 599 810 660 610 |
| 6868 | ADAM17 | 4703 | NP_003174.3 | in vitro;in vivo | 10527948 |
| 7916 | BAT2 | 807 | NP_542417.2 | yeast 2-hybrid | 14667819 |
| 8754 | ADAM9 | 4091 | NP_003807.1 | in vitro;in vivo;yeast 2-hybrid | 10527948 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Bacterial invasion of epithelial cells | hsa05100 |
| Cell cycle | hsa04110 |
| Oocyte meiosis | hsa04114 |
| Progesterone-mediated oocyte maturation | hsa04914 |
| Shigellosis | hsa05131 |
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 16130 |
|---|---|
| Molecular Class | Cell cycle control protein |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.