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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
MAP3K8 1326 mitogen-activated protein kinase kinase kinase 8  10Tpl-2, EST, c-COT, MEKK8 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
23027623   2012Cell line : -

Source : Twin Cities Metropolitan Area or a seven-county area of Utah or enrolled in the Kaiser Permanente Medical Care Program of Northern California (KPMCP).

Sample Type : Population-based case-control studies

No. of Sample : Colon 1555 cases, 1956 controls, rectal 754 cases, 959 controls

Stage : -

TagSNP selection and genotypingPolymorhpism--


Gene Details



NC_000010.10 (30722950..30750762)

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Gene Type protein coding
Gene Family Mitogen-activated protein kinase cascade / Kinase kinase kinases
Description This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]  
Chromosome 10
Location 10p11.2
Start 30722950  
End 30750762  
Strand +  
Gene Sequence

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Length 27813  
OMIM ID 191195   
HGNC ID HGNC:6860   
Unigene ID Hs.432453   
Ensembl ID ENSG00000107968   
PharmGKB ID PA30606   

mRNA Information


mRNA ID XM_011519309.1
Exon join(1..376,635..746,13780..13947,16256..16517, 17636..17742,24082..24234,25253..25499,26704..27831)  
mRNA Sequence

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Length 2553  



CDS Information


   
Location66..1556
CDS Sequence

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CCDS ID CCDS7166.1



Protein Information


      
Protein IDXP_011517611.1
Protein Namemitogen-activated protein kinase kinase kinase 8
Molecular Wt. (Da)55785
Protein Sequence

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Length 496  
Uniprot IDQ15366
Ensembl Protein ID ENSP00000352228  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation400
SPhosphorylation413
SPhosphorylation141

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                                            
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
4790NFKB11238NP_003989.2in vitro;in vivo;yeast 2-hybrid995   043   016   291   755   
7189TRAF63833NP_665802.1in vitro15670770   
8737RIPK14583NP_003795.2in vivo16291755   
9020MAP3K145230NP_003945.2in vitro;in vivo10   072   079   112   782   600   000   000   


Pathway Information


                        
Pathway Name Pathway ID
MAPK signaling pathway hsa04010
T cell receptor signaling pathway hsa04660
TNF signaling pathway hsa04668
Toll-like receptor signaling pathway hsa04620


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd13995133-388  STKc_MAP3K8
cl21453133-388  PKc_like superfamily
cd06606142-386  STKc_MAPKKK
cd05122136-386  PKc_STE
cd06627142-386  STKc_Cdc7_like
cd06609144-386  STKc_MST3_like
cd00180144-386  PKc
cd06625146-385  STKc_MEKK3_like
cd06613139-386  STKc_MAP4K3_like
cd14014136-384  STKc_PknB_like
cd06614144-389  STKc_PAK
cd06612146-385  STKc_MST1_2
cd05117146-386  STKc_CAMK
cd06623142-389  PKc_MAPKK_plant_like
cd06632142-385  STKc_MEKK1_plant
cd14007146-385  STKc_Aurora
cd13991144-382  STKc_NIK
cd06624146-388  STKc_ASK
cd06631130-385  STKc_YSK4
cd06626143-386  STKc_MEKK4
cd06611147-385  STKc_SLK_like
cd06641144-386  STKc_MST3
cd06917142-384  STKc_NAK1_like
cd06630147-387  STKc_MEKK1
cd06648144-388  STKc_PAK_II
cd14003144-386  STKc_AMPK-like
cd06640142-386  STKc_MST4
cd08215137-388  STKc_Nek
cd06610144-385  STKc_OSR1_SPAK
cd06608142-388  STKc_myosinIII_N_like
cd14008146-386  STKc_LKB1_CaMKK
cd06642142-386  STKc_STK25
cd06644147-385  STKc_STK10
cd06628144-385  STKc_Byr2_like
cd06653146-385  STKc_MEKK3_like_u1
cd06643147-396  STKc_SLK
cd06647144-388  STKc_PAK_I
cd14116132-385  STKc_Aurora-A
cd06659110-398  STKc_PAK6
cd06652146-385  STKc_MEKK2
cd14099142-386  STKc_PLK
cd06629142-386  STKc_Bck1_like
cd13999144-377  STKc_MAP3K-like
cd06646137-385  STKc_MAP4K5
cd08217142-385  STKc_Nek2
cd05123146-376  STKc_AGC
cd06605146-385  PKc_MAPKK
cd06621147-385  PKc_Pek1_like
cd06607144-388  STKc_TAO
cd06636147-385  STKc_MAP4K4_6_N
cd06656144-388  STKc_PAK3
cd06637142-402  STKc_TNIK
cd06620134-386  PKc_Byr1_like
cd06645134-385  STKc_MAP4K3
cd06651146-385  STKc_MEKK3
cd06655144-388  STKc_PAK2
cd13997137-386  PKc_Wee1_like
cd14058146-377  STKc_TAK1
cd14098141-386  STKc_Rad53_Cds1
cd06654144-388  STKc_PAK1
cd05118136-386  STKc_CMGC
cd06638144-386  STKc_myosinIIIA_N
cd14002144-385  STKc_STK36
cd14006144-385  STKc_MLCK-like
cd05611144-376  STKc_Rim15_like
cd05579144-385  STKc_MAST_like
cd13996118-383  STKc_EIF2AK
cd06658110-391  STKc_PAK5
cd06657110-391  STKc_PAK4
cd06639142-385  STKc_myosinIIIB_N
cd14069147-385  STKc_Chk1
cd06633144-415  STKc_TAO3
cd14009144-376  STKc_ATG1_ULK_like
cd08530142-388  STKc_CNK2-like
cd14050144-385  PKc_Myt1
cd14091144-386  STKc_RSK_C
cd07829144-385  STKc_CDK_like
cd06635144-385  STKc_TAO1
cd14080147-386  STKc_TSSK-like
cd13993144-384  STKc_Pat1_like
cd06634144-415  STKc_TAO2
cd14663143-386  STKc_SnRK3
cd13979143-384  STKc_Mos
cd14189146-386  STKc_PLK3
cd07832144-385  STKc_CCRK
cd14119147-386  STKc_LKB1
cd14066144-385  STKc_IRAK
cd14079146-386  STKc_AMPK_alpha
cd14187143-386  STKc_PLK1
cd14201142-376  STKc_ULK2
cd14202142-389  STKc_ULK1
cd14095147-386  STKc_DCKL
cd14188146-386  STKc_PLK2
cd14010142-386  STKc_ULK4
cd06618139-386  PKc_MKK7
cd08222137-385  STKc_Nek11
cd06617146-385  PKc_MKK3_6
cd00192146-385  PTKc
cd14084131-333  STKc_Chk2
cd14166147-385  STKc_CaMKI_gamma
cd14097146-386  STKc_STK33
cd08529144-388  STKc_FA2-like
cd13978146-377  STKc_RIP
cd05578144-376  STKc_Yank1
cd14047135-385  STKc_EIF2AK2_PKR
cd14087144-388  STKc_PSKH1
cd14133142-385  PKc_DYRK_like
cd07841142-386  STKc_CDK7
cd14120144-385  STKc_ULK1_2-like
cd14167142-385  STKc_CaMKI_alpha
cd08220146-385  STKc_Nek8
cd13983146-385  STKc_WNK
cd06622146-385  PKc_PBS2_like
cd08225144-384  STKc_Nek5
cd07834143-417  STKc_MAPK
cd14083142-376  STKc_CaMKI
cd14117146-385  STKc_Aurora-B_like
cd14131142-388  PKc_Mps1
cd06619142-385  PKc_MKK5
cd14072144-327  STKc_MARK
cd13987146-385  STKc_SBK1
cd14168132-385  STKc_CaMKI_delta
cd14086146-385  STKc_CaMKII
cd14081131-385  STKc_BRSK1_2
cd13985147-383  STKc_GAK_like
cd13994144-384  STKc_HAL4_like
cd14177149-385  STKc_RSK4_C
cd14106138-385  STKc_DRAK
cd05581144-377  STKc_PDK1
cd07838144-386  STKc_CDK4_6_like
cd14103146-314  STKc_MLCK
cd08224144-384  STKc_Nek6_7
cd06616144-386  PKc_MKK4
cd08218144-384  STKc_Nek1
cd14190147-328  STKc_MLCK2
cd05610144-385  STKc_MASTL
cd14186146-385  STKc_PLK4
cd06615146-385  PKc_MEK
cd14173141-385  STKc_Mnk2
cd06650164-391  PKc_MEK1
cd14090132-330  STKc_Mnk
cd08221146-384  STKc_Nek9
cd14046143-386  STKc_EIF2AK4_GCN2_rpt2
cd08528142-377  STKc_Nek10
cd05574146-376  STKc_phototropin_like
cd14111146-333  STKc_SPEG_rpt2
cd14158147-326  STKc_IRAK4
cd14178160-385  STKc_RSK3_C
cd13988146-327  STKc_TBK1
cd14088149-386  STKc_CaMK_like
cd14169144-385  STKc_CaMKI_beta
cd14019144-386  STKc_Cdc7
cd05580136-336  STKc_PKA_like
cd13986147-391  STKc_16
cd14075144-388  STKc_NIM1
cd07851130-402  STKc_p38
cd05609144-376  STKc_MAST
cd07840147-386  STKc_CDK9_like
cd14164144-388  STKc_TSSK6-like
cd14104146-388  STKc_Titin
cd14665137-386  STKc_SnRK2-3
cd14121177-376  STKc_ULK3
cd05572146-326  STKc_cGK
cd14094142-418  STKc_CASK
cd07831136-386  STKc_MOK
cd14052138-386  PTKc_Wee1_fungi
cd05584146-327  STKc_p70S6K
cd14198135-385  STKc_DRAK2
cd07845144-325  STKc_CDK10
cd08228144-377  STKc_Nek6
cd14096147-385  STKc_RCK1-like
cd07852144-398  STKc_MAPK15-like
cd14109136-385  PK_Unc-89_rpt1
cd14192147-388  STKc_MLCK3
cd14093160-386  STKc_PhKG
cd05573141-326  STKc_ROCK_NDR_like
cd07849138-390  STKc_ERK1_2_like
cd14185144-385  STKc_DCKL3
cd07830147-385  STKc_MAK_like
cd14070144-388  STKc_HUNK
cd14175160-399  STKc_RSK1_C
cd14196150-328  STKc_DAPK2
cd14060147-383  STKc_MLTK
cd07835144-386  STKc_CDK1_CdkB_like
cd14210233-325  PKc_DYRK
cd07833136-385  STKc_CDKL
cd14012186-386  PK_eIF2AK_GCN2_rpt1
cd14176160-385  STKc_RSK2_C
cd14118204-376  STKc_CAMKK
cd14165137-385  STKc_TSSK1_2-like
cd14004146-385  STKc_PASK
cd08219144-388  STKc_Nek3
cd14105150-385  STKc_DAPK
cd14197182-388  STKc_DRAK1
cd14073146-326  STKc_NUAK
cd14136233-388  STKc_SRPK
cd14107144-386  STKc_obscurin_rpt1
cd14174132-328  STKc_Mnk1
cd14194136-385  STKc_DAPK1
cd05582146-327  STKc_RSK_N
cd05614147-419  STKc_MSK2_N
cd14062139-377  STKc_Raf
cd14137144-386  STKc_GSK3
cd07862144-387  STKc_CDK6
cd05583147-384  STKc_MSK_N
cd13989147-332  STKc_IKK
cd05612147-336  STKc_PRKX_like
cd07855137-400  STKc_ERK5
cd14065144-385  PKc_LIMK_like
cd14112139-388  STKc_Unc-89_rpt2
cd14662137-385  STKc_SnRK2
cd14162142-326  STKc_TSSK4-like
cd14059147-385  STKc_MAP3K12_13
cd07863147-385  STKc_CDK4
cd14193147-328  STKc_MLCK4
cd14110144-384  STKc_obscurin_rpt2
cd14163144-374  STKc_TSSK3-like
cd05613147-384  STKc_MSK1_N
cd14113132-388  STKc_Trio_C
cd14016132-327  STKc_CK1
cd05616146-327  STKc_cPKC_beta
cd07860144-386  STKc_CDK2_3
cd14146147-385  STKc_MLK4
cd14191147-328  STKc_MLCK1
cd14063141-384  PK_KSR
cd08223144-385  STKc_Nek4
cd14150144-377  STKc_A-Raf
cd05604144-376  STKc_SGK3
cd05049147-389  PTKc_Trk
cd07877120-412  STKc_p38alpha
cd14664144-384  STK_BAK1_like
cd07854147-399  STKc_MAPK4_6
cd14134147-386  PKc_CLK
cd14184144-385  STKc_DCKL2
cd13990146-386  STKc_TLK
cd14051186-385  PTKc_Wee1
cd14033144-385  STKc_WNK4
cd14074146-385  STKc_SNRK
cd14148147-384  STKc_MLK2
cd07856147-392  STKc_Sty1_Hog1
cd14195150-328  STKc_DAPK3
cd14048141-386  STKc_EIF2AK3_PERK
cd05577144-376  STKc_GRK
cd13982227-385  STKc_IRE1
cd08229144-377  STKc_Nek7
cd05575241-376  STKc_SGK
cd07878132-421  STKc_p38beta
cd14001205-326  PKc_TOPK
cd05608132-376  STKc_GRK1
cd05619133-327  STKc_nPKC_theta
cd05603144-391  STKc_SGK2
cd05597141-371  STKc_DMPK_like
cd14149144-385  STKc_C-Raf
cd14031146-385  STKc_WNK3
cd14061144-384  STKc_MLK
cd14179159-388  STKc_MSK1_C
cd14023144-385  PK_TRB1
cd05624144-371  STKc_MRCK_beta
cd13992186-377  PK_GC
cd07880147-417  STKc_p38gamma
cd05602141-381  STKc_SGK1
cd06649147-332  PKc_MEK2
cd05599141-366  STKc_NDR_like
cd14199187-376  STKc_CaMKK2
cd08216152-385  PK_STRAD
cd14078136-385  STKc_MELK
cd07846185-386  STKc_CDKL2_3
cd14027147-377  STKc_RIP1
cd14005215-385  STKc_PIM
cd05622144-356  STKc_ROCK1
cd14077147-386  STKc_Kin1_2
cd07879132-411  STKc_p38delta
cd14115144-385  STKc_Kalirin_C
cd14114147-388  STKc_Twitchin_like
cd14182187-385  STKc_PhKG1
cd14145142-383  STKc_MLK1
cd05040186-382  PTKc_Ack_like
cd05623144-365  STKc_MRCK_alpha
cd05615146-327  STKc_cPKC_alpha
cd14039147-328  STKc_IKK_alpha
cd13976150-385  PK_TRB
cd14151144-377  STKc_B-Raf
cd14024150-388  PK_TRB3
cd07843144-386  STKc_CDC2L1
cd14221146-382  STKc_LIMK1
cd05596141-357  STKc_ROCK
cd14017132-329  STKc_TTBK
cd05039144-384  PTKc_Csk_like
cd05592146-411  STKc_nPKC_theta_like
cd14181213-385  STKc_PhKG2
cd14200201-385  STKc_CaMKK1
cd14082121-327  STKc_PKD
cd05148147-322  PTKc_Srm_Brk
cd14064144-350  PKc_TNNI3K
cd14161146-385  STKc_NUAK2
cd14101146-385  STKc_PIM2
cd14011237-386  PK_SCY1_like
cd14183131-389  STKc_DCKL1
cd13981146-324  STKc_Bub1_BubR1
cd14071144-327  STKc_SIK
cd14025136-377  STKc_RIP4_like
cd05585201-376  STKc_YPK1_like
cd14036144-383  STKc_GAK
cd14022152-385  PK_TRB2
cd13974227-385  STKc_SHIK
cd05621144-347  STKc_ROCK2
cd14092159-390  STKc_MSK_C
cd14226118-325  PKc_DYRK1
cd14049142-386  STKc_EIF2AK1_HRI
cd14154144-317  STKc_LIMK
cd05084144-317  PTKc_Fes
cd08226151-393  PK_STRAD_beta
cd05630136-376  STKc_GRK6
cd05098116-325  PTKc_FGFR1
cd14222149-377  STKc_LIMK2
cd05092147-382  PTKc_TrkA
cd07857131-400  STKc_MPK1
cd07853144-392  STKc_NLK
cd14223144-376  STKc_GRK2
cd05587146-327  STKc_cPKC
cd14147142-388  STKc_MLK3
cd07850237-395  STKc_JNK
cd07836147-385  STKc_Pho85
cd14085146-385  STKc_CaMKIV
cd14076144-388  STKc_Kin4
cd14207206-384  PTKc_VEGFR1
cd13975144-377  PKc_Dusty
cd14156144-384  PKc_LIMK_like_unk
cd05034146-337  PTKc_Src_like
cd14159144-326  STKc_IRAK1
cd07842135-314  STKc_CDK8_like
cd07865144-325  STKc_CDK9
cd05606144-376  STKc_beta_ARK
cd05620146-430  STKc_nPKC_delta
cd07871142-420  STKc_PCTAIRE3
cd07873142-420  STKc_PCTAIRE1
cd14100235-386  STKc_PIM1
cd14180181-345  STKc_MSK2_C
cd05045147-384  PTKc_RET
cd14155139-385  PKc_TESK
cd05595146-389  STKc_PKB_beta
cd05598144-332  STKc_LATS
cd07847230-386  STKc_CDKL1_4
cd14038205-328  STKc_IKK_beta
cd05101147-384  PTKc_FGFR2
cd05072147-377  PTKc_Lyn
cd05607146-327  STKc_GRK7
cd05085142-384  PTKc_Fer
cd07839144-385  STKc_CDK5
cd05586212-381  STKc_Sck1_like
cd05054146-385  PTKc_VEGFR
cd05633144-376  STKc_GRK3
cd05083132-377  PTKc_Chk
cd14127213-354  STKc_CK1_fungal
cd05038146-382  PTKc_Jak_rpt2
cd14037142-377  STKc_NAK_like
cd14170147-424  STKc_MAPKAPK2
cd14209147-386  STKc_PKA
cd14053144-299  STKc_ACVR2
cd14203147-377  PTKc_Src_Fyn_like
cd14032146-385  STKc_WNK2_like
cd05053147-384  PTKc_FGFR
cd05593146-376  STKc_PKB_gamma
cd14030144-385  STKc_WNK1
cd07876236-417  STKc_JNK2
cd07866147-325  STKc_BUR1
cd14000146-391  STKc_LRRK
cd14172205-385  STKc_MAPKAPK3
cd05046144-384  PTK_CCK4
cd05059131-314  PTKc_Tec_like
cd08227174-385  PK_STRAD_alpha
cd05590146-327  STKc_nPKC_eta
cd05093147-327  PTKc_TrkB
cd07870185-385  STKc_PFTAIRE2
cd14132136-320  STKc_CK2_alpha
cd14068147-380  STKc_LRRK2
cd05112131-387  PTKc_Itk
cd05041144-317  PTKc_Fes_like
cd14125137-327  STKc_CK1_delta_epsilon
cd05075147-396  PTKc_Axl
cd05570146-410  STKc_PKC
cd07874236-417  STKc_JNK3
smart00750213-385  KIND
cd05628144-336  STKc_NDR1
cd14129132-329  STKc_TTBK2
cd05600141-326  STKc_Sid2p_like
cd05079147-322  PTKc_Jak1_rpt2
cd05044143-377  PTKc_c-ros
cd07848147-350  STKc_CDKL5
cd14225237-325  PKc_DYRK4
cd05627144-336  STKc_NDR2
cd07872147-416  STKc_PCTAIRE2
cd14128137-327  STKc_CK1_alpha
cd05103229-385  PTKc_VEGFR2
cd14140146-388  STKc_ACVR2b
cd05631136-376  STKc_GRK4
cd07859237-411  STKc_TDY_MAPK
cd13977144-320  STKc_PDIK1L
cd05073147-337  PTKc_Hck
cd14108144-328  STKc_SPEG_rpt1
cd05082132-382  PTKc_Csk
cd14152142-335  STKc_KSR1
cd14055144-320  STKc_TGFbR2_like
cd05629144-376  STKc_NDR_like_fungal
cd07858237-400  STKc_TEY_MAPK
cd05052147-389  PTKc_Abl
cd05071146-377  PTKc_Src
cd14139187-385  PTKc_Wee1b
cd05061146-394  PTKc_InsR
cd05601141-326  STKc_CRIK
cd05055147-317  PTKc_PDGFR
cd05068137-339  PTKc_Frk_like
cd14040146-327  STKc_TLK1
cd05100147-384  PTKc_FGFR3
cd14138186-385  PTKc_Wee1a
cd05036147-317  PTKc_ALK_LTK
cd05594146-376  STKc_PKB_alpha
cd05626147-332  STKc_LATS2
cd05056185-314  PTKc_FAK
cd14102235-385  STKc_PIM3
cd05632136-333  STKc_GRK5
cd05066177-383  PTKc_EphR_A
cd05094147-332  PTKc_TrkC
cd07875236-323  STKc_JNK1
cd07861144-325  STKc_CDK1_euk
cd05063144-383  PTKc_EphR_A2
cd14041146-327  STKc_TLK2
cd14220144-376  STKc_BMPR1a
cd14089150-385  STKc_MAPKAPK
cd14205178-401  PTKc_Jak2_rpt2
cd14126144-327  STKc_CK1_gamma
cd07844135-386  STKc_PCTAIRE_like
cd05589146-376  STKc_PKN
cd05058144-327  PTKc_Met_Ron
cd05067147-377  PTKc_Lck_Blk
cd14015236-329  STKc_VRK
cd14216233-323  STKc_SRPK1
cd05099186-377  PTKc_FGFR4
cd14130147-329  STKc_TTBK1
cd14153142-273  PK_KSR2
cd05048147-317  PTKc_Ror
cd05591146-327  STKc_nPKC_epsilon
cd14020187-323  STKc_KIS
cd13998144-388  STKc_TGFbR-like
cd05060187-327  PTKc_Syk_like
cd14204147-385  PTKc_Mer
cd05032146-377  PTKc_InsR_like
cd05104236-377  PTKc_Kit
cd14144186-376  STKc_BMPR1
cd14171147-338  STKc_MAPKAPK5
cd14213236-323  PKc_CLK1_4
cd05057147-327  PTKc_EGFR_like
cd14224237-325  PKc_DYRK2_3
cd05090178-382  PTKc_Ror1
cd05069146-377  PTKc_Yes
cd05605237-330  STKc_GRK4_like
cd13968144-272  PKc_like
cd05102224-317  PTKc_VEGFR3
cd05113187-317  PTKc_Btk_Bmx
cd05116147-377  PTKc_Syk
cd13980232-384  STKc_Vps15
cd14054144-314  STKc_BMPR2_AMHR2
cd05035146-377  PTKc_TAM
cd14211142-353  STKc_HIPK
cd14212233-314  PKc_YAK1
cd14135234-323  STKc_PRP4
cd05091149-382  PTKc_Ror2
cd05625147-332  STKc_LATS1
cd14141146-317  STKc_ACVR2a
cd05065177-383  PTKc_EphR_B
cd05033147-383  PTKc_EphR
cd05047142-325  PTKc_Tie
cd05107236-332  PTKc_PDGFR_beta
cd14214236-323  PKc_CLK3
cd05105229-341  PTKc_PDGFR_alpha
cd05114131-314  PTKc_Tec_Rlk
cd14013223-320  STKc_SNT7_plant
TIGR03724244-281  arch_bud32
COG3642244-274  Bud32
smart00220146-386  S_TKc
pfam00069146-386  Pkinase
COG0515143-420  SPS1
smart00219146-384  TyrKc
smart00221146-384  STYKc
pfam07714146-385  Pkinase_Tyr
PTZ00267177-388  PTZ00267
PLN00034137-406  PLN00034
PTZ00283224-407  PTZ00283
PTZ00263132-340  PTZ00263
PHA03207138-320  PHA03207
PTZ00024136-386  PTZ00024
PHA03390147-389  pk1
PTZ00266144-391  PTZ00266
PRK13184144-327  pknD
PHA03209224-381  PHA03209
PTZ00426147-385  PTZ00426
PLN00009144-386  PLN00009
TIGR03903160-325  TOMM_kin_cyc
PTZ00036123-359  PTZ00036
PHA03212229-323  PHA03212
PHA03210230-320  PHA03210
PLN03225223-320  PLN03225
PLN00113144-326  PLN00113


Ontology Information


   
HPRD ID1982
Molecular ClassSerine/threonine kinase
Molecular FunctionLigase activity (GO:0016874)
Biological ProcessMetabolism (GO:0008152); Energy pathways (GO:0006091)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO