CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
23027623	2012	Cell line : - Source : Twin Cities Metropolitan Area or a seven-county area of Utah or enrolled in the Kaiser Permanente Medical Care Program of Northern California (KPMCP). Sample Type : Population-based case-control studies No. of Sample : Colon: n = 1555 cases, 1956 controls; rectal: n = 754 cases, 959 controls Stage : -	TagSNP selection and genotyping	Polymorhpism	-	Mitogen-activated protein kinase (MAPK) pathways regulate many cellular functions including cell proliferation, differentiation, migration and apoptosis.
23859041	2013	Cell line : - Source : Twin Cities Metropolitan Area or a seven-county area of Utah or enrolled in the Kaiser Permanente Medical Care Program of Northern California (KPMCP). Sample Type : Population-based case-control studies No. of Sample : Colon: n = 1555 cases, 1956 controls; rectal: n = 754 cases, 959 controls Stage : -	TagSNP selection and genotyping	Polymorhpism	-	Mitogen-activated protein kinase (MAPK) pathways regulate cellular functions including cell proliferation, differentiation, migration, and apoptosis. Data suggest that dietary factors involved in inflammation and oxidative stress interact with MAPK-signaling genes to alter risk of colorectal cancer. Population-based case-control studies data include colon cases (n = 1555) and controls (n = 1956) and rectal cases (n = 754) and controls (n = 959).

Gene Details

NC_000010.10 (49514682..49647403)
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Gene Type	protein coding
Gene Family	Mitogen-activated protein kinase cascade / Kinases
Description	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jun 2013]
Chromosome	10
Location	10q11
Start	49514682
End	49647403
Strand	+
Gene Sequence	Download   Select all
Length	132722
OMIM ID	601158
HGNC ID	HGNC:6881
Unigene ID	Hs.138211
Ensembl ID	ENSG00000107643
PharmGKB ID	PA283

mRNA Information

mRNA ID	?NM_001278547.1
Exon	join(1..183,94974..95144,98214..98343,103241..103299, 103392..103530,113517..113682,117876..117947, 119250..119432,119742..119866,120442..120505, 124555..124632,128246..132722)
mRNA Sequence	Download   Select all
Length	5854

CDS Information

   

Location	233..1516
CDS Sequence	Download   Select all
CCDS ID	CCDS60527.1

Protein Information

      

Protein ID	NP_001265476.1
Protein Name	mitogen-activated protein kinase 8
Molecular Wt. (Da)	41226
Protein Sequence	Download   Select all
Length	427
Uniprot ID	O43791
Ensembl Protein ID	ENSP00000240327

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	377
S	Phosphorylation	377
Y	Phosphorylation	185
Y	Phosphorylation	185
Y	Phosphorylation	185
Y	Phosphorylation	185
T	Phosphorylation	183
T	Phosphorylation	183
T	Phosphorylation	183
T	Phosphorylation	183
Y	Phosphorylation	185
Y	Phosphorylation	185
Y	Phosphorylation	185
Y	Phosphorylation	185
S	Phosphorylation	377
S	Phosphorylation	377
Y	Phosphorylation	357
T	Phosphorylation	367
Y	Phosphorylation	357
T	Phosphorylation	367
Y	Phosphorylation	357
T	Phosphorylation	367
Y	Phosphorylation	357
T	Phosphorylation	367
T	Phosphorylation	255
T	Phosphorylation	258
Y	Phosphorylation	259
T	Phosphorylation	255
T	Phosphorylation	258
Y	Phosphorylation	259
T	Phosphorylation	255
T	Phosphorylation	258
Y	Phosphorylation	259
T	Phosphorylation	255
T	Phosphorylation	258
Y	Phosphorylation	259
K	Acetylation	308
K	Acetylation	308
K	Acetylation	308
K	Acetylation	308

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
572	BAD	4409	NP_004313.1	in vitro	14967141
596	BCL2	1045	NP_000624.2	in vivo	105   675   721   203   986   000   000   000
1026	CDKN1A	298	NP_510867.1	in vitro;in vivo	12058028
1386	ATF2	443	NP_001871.2	in vitro;in vivo	77   371   307   737   129
1398	CRK	1267	NP_058431.2	in vitro;in vivo	11432831
1432	MAPK14	2619	NP_001306.1	in vivo	15778365
1843	DUSP1	2835	NP_004408.1	yeast 2-hybrid	11278799
2004	ELK3	2593	NP_005221.2	in vitro	11042694
2547	XRCC6	1071	NP_001460.1	in vitro;in vivo	11749722
2908	NR3C1	679	NP_001019265.1	in vitro;in vivo	123   517   029   199   329
2950	GSTP1	614	NP_000843.1	in vitro;in vivo	1   264   656   411   279   190
3265	HRAS	1813	NP_005334.1	in vivo	81   374   211   152   564   900   000   000
3297	HSF1	778	NP_005517.1	in vitro;in vivo	10747973
3299	HSF4	3896	NP_001035757.1	in vitro	16581800
3667	IRS1	943	NP_005535.1	in vitro;in vivo;yeast 2-hybrid	12   417   588   116   065   600   000   000   000   000   000
3725	JUN	1302	NP_002219.1	in vitro;in vivo	8   137   421   153   029   350   000   000   000   000   000   000   000
3726	JUNB	1303	NP_002220.1	in vitro;in vivo	940   541   698   891   988   000   000
3727	JUND	1304	NP_005345.3	in vitro	12052834
3856	KRT8	1015	NP_002264.1	in vitro;in vivo	11   788   583   117   813   200   000   000
4087	SMAD2	3221	NP_005892.1	in vitro;in vivo	15326485
4131	MAP1B	1139	NP_005900.2	in vivo	12689591
4609	MYC	1818	NP_002458.2	in vitro;in vivo	105   518   111   748   630
5076	PAX2	1330	NP_003981.2	in vitro;in vivo	11700324
5295	PIK3R1	1381	NP_852664.1	in vivo	7642542
5468	PPARG	3288	NP_056953.2	in vitro;in vivo	9030579
5591	PRKDC	2941	NP_008835.5	in vitro;in vivo	11749722
5594	MAPK1	1496	NP_002736.3	in vivo	15778365
5595	MAPK3	3479	NP_002737.2	in vivo	15778365
5829	PXN	3937	BAA18998.1	in vitro;in vivo	12853963
5966	REL	1286	NP_002899.1	in vivo;yeast 2-hybrid	8621542
6198	RPS6KB1	10202	NP_003152.1	in vitro;in vivo	11279232
6774	STAT3	26	NP_644805.1	in vitro;in vivo	11   350   938   105   215   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000
7157	TP53	1859	NP_000537.3	in vitro;in vivo	9   732   264   939   387   310   000   000
7534	YWHAZ	3183	NP_003397.1	in vivo	15696159
9318	COPS2	5146	NP_001137359.1	in vivo	10585392
9479	MAPK8IP1	5223	NP_005447.1	in vitro;in vivo	97   335   131   275   625   400   000   000
10018	BCL2L11	4828	NP_619527.1	in vitro;in vivo	1   259   195   012   818   170
11186	RASSF1	5470	NP_733832.1	in vivo	16810318
29904	EEF2K	7369	NP_037434.1	in vitro	12171600
90427	BMF	5881	NP_277038.1	in vitro	12591950
122953	JDP2	16360	NP_001128521.1	in vitro;in vivo	1   222   528   911   602   240

Pathway Information

                                                                                                                                                                                                                                                                              

Pathway Name	Pathway ID
Adipocytokine signaling pathway	hsa04920
AGE-RAGE signaling pathway in diabetic complications	hsa04933
cAMP signaling pathway	hsa04024
Chagas disease (American trypanosomiasis)	hsa05142
Choline metabolism in cancer	hsa05231
Colorectal cancer	hsa05210
Dopaminergic synapse	hsa04728
Epithelial cell signaling in Helicobacter pylori infection	hsa05120
Epstein-Barr virus infection	hsa05169
ErbB signaling pathway	hsa04012
Fc epsilon RI signaling pathway	hsa04664
Focal adhesion	hsa04510
FoxO signaling pathway	hsa04068
GnRH signaling pathway	hsa04912
Hepatitis B	hsa05161
Hepatitis C	hsa05160
Herpes simplex infection	hsa05168
HTLV-I infection	hsa05166
Inflammatory mediator regulation of TRP channels	hsa04750
Influenza A	hsa05164
Insulin resistance	hsa04931
Insulin signaling pathway	hsa04910
MAPK signaling pathway	hsa04010
Neurotrophin signaling pathway	hsa04722
NOD-like receptor signaling pathway	hsa04621
Non-alcoholic fatty liver disease (NAFLD)	hsa04932
Osteoclast differentiation	hsa04380
Pancreatic cancer	hsa05212
Pathways in cancer	hsa05200
Pertussis	hsa05133
Progesterone-mediated oocyte maturation	hsa04914
Prolactin signaling pathway	hsa04917
Protein processing in endoplasmic reticulum	hsa04141
Ras signaling pathway	hsa04014
Retrograde endocannabinoid signaling	hsa04723
RIG-I-like receptor signaling pathway	hsa04622
Salmonella infection	hsa05132
Shigellosis	hsa05131
Sphingolipid signaling pathway	hsa04071
TNF signaling pathway	hsa04668
Toll-like receptor signaling pathway	hsa04620
Toxoplasmosis	hsa05145
Tuberculosis	hsa05152
Type II diabetes mellitus	hsa04930
Wnt signaling pathway	hsa04310

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd07850	25-360	STKc_JNK
cl21453	25-360	PKc_like superfamily
cd07875	1-364	STKc_JNK1
cd07874	8-362	STKc_JNK3
cd07876	4-362	STKc_JNK2
cd07834	25-359	STKc_MAPK
cd07851	10-364	STKc_p38
cd07878	10-364	STKc_p38beta
cd07879	10-362	STKc_p38delta
cd07877	10-364	STKc_p38alpha
cd07880	10-364	STKc_p38gamma
cd07849	20-361	STKc_ERK1_2_like
cd07855	20-359	STKc_ERK5
cd07858	20-361	STKc_TEY_MAPK
cd07857	25-360	STKc_MPK1
cd07852	22-360	STKc_MAPK15-like
cd05118	26-321	STKc_CMGC
cd07856	18-359	STKc_Sty1_Hog1
cd07853	30-362	STKc_NLK
cd07829	26-321	STKc_CDK_like
cd07859	25-362	STKc_TDY_MAPK
cd14137	21-320	STKc_GSK3
cd07841	25-342	STKc_CDK7
cd07838	26-320	STKc_CDK4_6_like
cd07832	25-320	STKc_CCRK
cd07830	26-320	STKc_MAK_like
cd07835	26-320	STKc_CDK1_CdkB_like
cd07833	25-320	STKc_CDKL
cd07840	26-320	STKc_CDK9_like
cd07854	25-327	STKc_MAPK4_6
cd07831	26-320	STKc_MOK
cd07860	26-320	STKc_CDK2_3
cd07842	25-320	STKc_CDK8_like
cd07843	26-321	STKc_CDC2L1
cd05117	25-319	STKc_CAMK
cd07845	23-339	STKc_CDK10
cd07866	21-320	STKc_BUR1
cd14133	26-321	PKc_DYRK_like
cd07839	25-320	STKc_CDK5
cd07846	25-320	STKc_CDKL2_3
cd07863	25-321	STKc_CDK4
cd07861	26-320	STKc_CDK1_euk
cd14003	25-320	STKc_AMPK-like
cd14210	9-321	PKc_DYRK
cd07836	26-320	STKc_Pho85
cd07844	26-320	STKc_PCTAIRE_like
cd14014	25-261	STKc_PknB_like
cd14135	25-321	STKc_PRP4
cd14226	11-322	PKc_DYRK1
cd07847	25-320	STKc_CDKL1_4
cd07848	25-319	STKc_CDKL5
cd07837	26-322	STKc_CdkB_plant
cd05122	26-321	PKc_STE
cd00180	32-319	PKc
cd07862	24-320	STKc_CDK6
cd14132	25-320	STKc_CK2_alpha
cd07873	23-320	STKc_PCTAIRE1
cd06614	26-322	STKc_PAK
cd08215	25-321	STKc_Nek
cd07865	24-320	STKc_CDK9
cd07871	20-320	STKc_PCTAIRE3
cd07864	21-321	STKc_CDK12
cd14084	24-321	STKc_Chk2
cd06606	25-321	STKc_MAPKKK
cd13999	32-252	STKc_MAP3K-like
cd07872	20-320	STKc_PCTAIRE2
cd07870	26-320	STKc_PFTAIRE2
cd14092	15-335	STKc_MSK_C
cd14098	25-320	STKc_Rad53_Cds1
cd07869	26-322	STKc_PFTAIRE1
cd14212	33-321	PKc_YAK1
cd14136	13-321	STKc_SRPK
cd14007	29-321	STKc_Aurora
cd05123	32-320	STKc_AGC
cd14225	8-321	PKc_DYRK4
cd14080	26-321	STKc_TSSK-like
cd14009	32-320	STKc_ATG1_ULK_like
cd14211	26-321	STKc_HIPK
cd14081	30-321	STKc_BRSK1_2
cd14134	11-320	PKc_CLK
cd14008	32-321	STKc_LKB1_CaMKK
cd06627	25-321	STKc_Cdc7_like
cd07867	23-320	STKc_CDC2L6
cd14229	26-321	STKc_HIPK3
cd06648	25-321	STKc_PAK_II
cd14002	25-321	STKc_STK36
cd13996	24-248	STKc_EIF2AK
cd06610	24-321	STKc_OSR1_SPAK
cd14079	26-320	STKc_AMPK_alpha
cd14224	25-321	PKc_DYRK2_3
cd14162	26-325	STKc_TSSK4-like
cd14099	24-321	STKc_PLK
cd14179	30-339	STKc_MSK1_C
cd07868	23-320	STKc_CDK8
cd06623	27-322	PKc_MAPKK_plant_like
cd14096	25-321	STKc_RCK1-like
cd08530	25-319	STKc_CNK2-like
cd14091	67-347	STKc_RSK_C
cd14119	32-320	STKc_LKB1
cd08217	26-321	STKc_Nek2
cd14165	32-321	STKc_TSSK1_2-like
cd14046	25-221	STKc_EIF2AK4_GCN2_rpt2
cd05581	30-320	STKc_PDK1
cd14097	24-321	STKc_STK33
cd13993	25-222	STKc_Pat1_like
cd14167	32-321	STKc_CaMKI_alpha
cd14228	26-323	STKc_HIPK1
cd14069	32-325	STKc_Chk1
cd14089	69-320	STKc_MAPKAPK
cd14082	32-320	STKc_PKD
cd06625	30-321	STKc_MEKK3_like
cd06626	25-321	STKc_MEKK4
cd13994	32-321	STKc_HAL4_like
cd06647	24-321	STKc_PAK_I
cd08224	25-220	STKc_Nek6_7
cd14072	25-262	STKc_MARK
cd14121	32-320	STKc_ULK3
cd14227	26-323	STKc_HIPK2
cd14173	32-321	STKc_Mnk2
cd14180	31-339	STKc_MSK2_C
cd14093	62-320	STKc_PhKG
cd14019	8-320	STKc_Cdc7
cd14175	75-321	STKc_RSK1_C
cd06612	32-321	STKc_MST1_2
cd08225	25-265	STKc_Nek5
cd14166	32-322	STKc_CaMKI_gamma
cd00192	30-219	PTKc
cd14086	14-321	STKc_CaMKII
cd06658	28-328	STKc_PAK5
cd14087	73-321	STKc_PSKH1
cd14120	32-320	STKc_ULK1_2-like
cd14213	25-320	PKc_CLK1_4
cd14090	31-321	STKc_Mnk
cd14083	22-320	STKc_CaMKI
cd08222	25-321	STKc_Nek11
cd08228	23-247	STKc_Nek6
cd06624	32-321	STKc_ASK
cd06655	13-323	STKc_PAK2
cd06628	32-321	STKc_Byr2_like
cd06659	27-321	STKc_PAK6
cd14118	32-321	STKc_CAMKK
cd08219	25-265	STKc_Nek3
cd08529	26-218	STKc_FA2-like
cd05611	29-320	STKc_Rim15_like
cd14073	25-321	STKc_NUAK
cd06605	27-322	PKc_MAPKK
cd06607	24-214	STKc_TAO
cd14095	73-320	STKc_DCKL
cd13982	30-320	STKc_IRE1
cd05578	26-321	STKc_Yank1
cd14048	23-219	STKc_EIF2AK3_PERK
cd05573	24-337	STKc_ROCK_NDR_like
cd14071	26-321	STKc_SIK
cd05579	32-322	STKc_MAST_like
cd06632	25-321	STKc_MEKK1_plant
cd14185	51-320	STKc_DCKL3
cd08221	26-225	STKc_Nek9
cd14085	30-321	STKc_CaMKIV
cd14178	75-321	STKc_RSK3_C
cd14663	25-320	STKc_SnRK3
cd06621	29-321	PKc_Pek1_like
cd14161	25-230	STKc_NUAK2
cd14006	32-320	STKc_MLCK-like
cd06656	13-323	STKc_PAK3
cd14131	24-320	PKc_Mps1
cd14052	25-217	PTKc_Wee1_fungi
cd05572	32-229	STKc_cGK
cd08218	25-225	STKc_Nek1
cd14106	30-321	STKc_DRAK
cd13985	25-215	STKc_GAK_like
cd06654	13-323	STKc_PAK1
cd08528	82-264	STKc_Nek10
cd14169	32-321	STKc_CaMKI_beta
cd14174	32-321	STKc_Mnk1
cd14078	22-321	STKc_MELK
cd14074	30-321	STKc_SNRK
cd14202	72-322	STKc_ULK1
cd06620	29-321	PKc_Byr1_like
cd13997	25-319	PKc_Wee1_like
cd14176	75-321	STKc_RSK2_C
cd05577	32-339	STKc_GRK
cd06631	32-222	STKc_YSK4
cd14103	32-321	STKc_MLCK
cd14004	26-321	STKc_PASK
cd05607	24-236	STKc_GRK7
cd06657	28-335	STKc_PAK4
cd05571	139-339	STKc_PKB
cd06609	24-321	STKc_MST3_like
cd14177	75-333	STKc_RSK4_C
cd14171	68-321	STKc_MAPKAPK5
cd14183	21-322	STKc_DCKL1
cd14164	26-219	STKc_TSSK6-like
cd14077	26-321	STKc_Kin1_2
cd14201	52-322	STKc_ULK2
cd05600	23-343	STKc_Sid2p_like
cd05584	62-344	STKc_p70S6K
cd14189	56-320	STKc_PLK3
cd14058	32-250	STKc_TAK1
cd14163	26-321	STKc_TSSK3-like
cd05592	105-339	STKc_nPKC_theta_like
cd14047	26-218	STKc_EIF2AK2_PKR
cd14214	123-320	PKc_CLK3
cd14200	25-321	STKc_CaMKK1
cd08220	25-227	STKc_Nek8
cd13989	32-220	STKc_IKK
cd14168	73-321	STKc_CaMKI_delta
cd14059	32-266	STKc_MAP3K12_13
cd06611	75-326	STKc_SLK_like
cd14088	68-321	STKc_CaMK_like
cd06652	30-321	STKc_MEKK2
cd14116	30-321	STKc_Aurora-A
cd14050	26-220	PKc_Myt1
cd05619	102-338	STKc_nPKC_theta
cd14109	30-321	PK_Unc-89_rpt1
cd14010	138-320	STKc_ULK4
cd14196	32-321	STKc_DAPK2
cd08229	17-244	STKc_Nek7
cd14070	32-219	STKc_HUNK
cd14184	24-320	STKc_DCKL2
cd14215	127-320	PKc_CLK2
cd06633	26-214	STKc_TAO3
cd05148	50-246	PTKc_Srm_Brk
cd14076	52-321	STKc_Kin4
cd05599	101-337	STKc_NDR_like
cd06629	32-321	STKc_Bck1_like
cd13979	27-231	STKc_Mos
cd14094	72-321	STKc_CASK
cd14181	26-320	STKc_PhKG2
cd14199	23-321	STKc_CaMKK2
cd05630	26-258	STKc_GRK6
cd06613	26-218	STKc_MAP4K3_like
cd14194	72-321	STKc_DAPK1
cd14066	32-219	STKc_IRAK
cd05604	29-338	STKc_SGK3
cd14039	32-220	STKc_IKK_alpha
cd14172	106-321	STKc_MAPKAPK3
cd14113	26-321	STKc_Trio_C
cd06653	30-222	STKc_MEKK3_like_u1
cd06635	24-222	STKc_TAO1
cd05575	30-338	STKc_SGK
cd05632	26-228	STKc_GRK5
cd06608	25-321	STKc_myosinIII_N_like
cd13988	32-212	STKc_TBK1
cd14075	32-219	STKc_NIM1
cd14182	75-320	STKc_PhKG1
cd14105	72-321	STKc_DAPK
cd05570	101-338	STKc_PKC
cd14665	25-320	STKc_SnRK2-3
cd14191	73-321	STKc_MLCK1
cd14188	24-320	STKc_PLK2
cd05620	104-338	STKc_nPKC_delta
cd05601	101-338	STKc_CRIK
cd14114	23-321	STKc_Twitchin_like
cd05605	123-228	STKc_GRK4_like
cd14170	106-354	STKc_MAPKAPK2
cd05059	29-228	PTKc_Tec_like
cd14060	33-227	STKc_MLTK
cd06644	73-267	STKc_STK10
cd14193	73-321	STKc_MLCK4
cd14195	72-323	STKc_DAPK3
cd06917	26-219	STKc_NAK1_like
cd14107	8-214	STKc_obscurin_rpt1
cd05580	29-220	STKc_PKA_like
cd05585	97-320	STKc_YPK1_like
cd14016	25-174	STKc_CK1
cd06616	27-267	PKc_MKK4
cd14187	57-225	STKc_PLK1
cd06638	26-321	STKc_myosinIIIA_N
cd05598	101-219	STKc_LATS
cd06617	32-321	PKc_MKK3_6
cd05603	30-240	STKc_SGK2
cd14662	25-320	STKc_SnRK2
cd14209	26-239	STKc_PKA
cd14218	13-321	STKc_SRPK3
cd05612	26-339	STKc_PRKX_like
cd05582	126-244	STKc_RSK_N
cd06630	32-222	STKc_MEKK1
cd06615	72-324	PKc_MEK
cd06639	75-212	STKc_myosinIIIB_N
cd13978	32-227	STKc_RIP
cd08223	25-321	STKc_Nek4
cd05595	126-345	STKc_PKB_beta
cd05593	123-338	STKc_PKB_gamma
cd05609	26-219	STKc_MAST
cd14020	75-323	STKc_KIS
cd06618	23-267	PKc_MKK7
cd06651	30-323	STKc_MEKK3
cd06634	24-212	STKc_TAO2
cd06643	73-263	STKc_SLK
cd05063	30-267	PTKc_EphR_A2
cd13998	32-252	STKc_TGFbR-like
cd05631	26-339	STKc_GRK4
cd13986	25-318	STKc_16
cd14049	23-218	STKc_EIF2AK1_HRI
cd13990	25-218	STKc_TLK
cd05038	24-221	PTKc_Jak_rpt2
cd06650	26-331	PKc_MEK1
cd05068	29-246	PTKc_Frk_like
cd05586	32-220	STKc_Sck1_like
cd05608	26-228	STKc_GRK1
cd14017	25-174	STKc_TTBK
cd14154	67-219	STKc_LIMK
cd14221	52-219	STKc_LIMK1
cd13991	104-221	STKc_NIK
cd14062	32-279	STKc_Raf
cd14117	30-321	STKc_Aurora-B_like
cd14005	25-320	STKc_PIM
cd05099	30-218	PTKc_FGFR4
cd14101	32-225	STKc_PIM2
cd14001	53-219	PKc_TOPK
cd05602	26-342	STKc_SGK1
cd05610	29-343	STKc_MASTL
cd14198	131-229	STKc_DRAK2
cd14190	32-321	STKc_MLCK2
cd13983	32-219	STKc_WNK
cd14061	32-252	STKc_MLK
cd14145	32-252	STKc_MLK1
cd14038	32-216	STKc_IKK_beta
cd05060	49-267	PTKc_Syk_like
cd14150	29-279	STKc_A-Raf
cd06619	27-226	PKc_MKK5
cd14216	13-321	STKc_SRPK1
cd06636	75-218	STKc_MAP4K4_6_N
cd14104	32-321	STKc_Titin
cd05048	52-247	PTKc_Ror
cd06645	26-218	STKc_MAP4K3
cd05085	69-267	PTKc_Fer
cd05053	29-219	PTKc_FGFR
cd14158	20-219	STKc_IRAK4
cd14155	63-219	PKc_TESK
cd14111	59-239	STKc_SPEG_rpt2
cd14056	122-220	STKc_TGFbR_I
cd05616	104-251	STKc_cPKC_beta
cd14186	51-321	STKc_PLK4
cd14115	32-320	STKc_Kalirin_C
cd14197	131-321	STKc_DRAK1
cd05084	66-217	PTKc_Fes
cd13987	52-215	STKc_SBK1
cd05034	52-247	PTKc_Src_like
cd05032	29-219	PTKc_InsR_like
cd05614	134-338	STKc_MSK2_N
cd05594	126-338	STKc_PKB_alpha
cd06637	75-218	STKc_TNIK
cd14068	32-267	STKc_LRRK2
cd14100	26-262	STKc_PIM1
cd05583	139-218	STKc_MSK_N
cd06641	26-218	STKc_MST3
cd14146	134-267	STKc_MLK4
cd14192	73-321	STKc_MLCK3
cd05596	26-339	STKc_ROCK
cd14036	32-215	STKc_GAK
cd05621	26-247	STKc_ROCK2
cd14148	134-247	STKc_MLK2
cd14011	121-261	PK_SCY1_like
cd14065	32-219	PKc_LIMK_like
cd05100	30-218	PTKc_FGFR3
cd05587	138-240	STKc_cPKC
cd05066	30-221	PTKc_EphR_A
cd14222	50-219	STKc_LIMK2
cd06646	26-212	STKc_MAP4K5
cd05083	23-218	PTKc_Chk
cd14142	122-227	STKc_ACVR1_ALK1
cd05626	26-334	STKc_LATS2
cd06649	26-229	PKc_MEK2
cd05033	30-252	PTKc_EphR
cd14013	134-320	STKc_SNT7_plant
cd05072	29-266	PTKc_Lyn
cd05112	32-218	PTKc_Itk
cd05067	50-247	PTKc_Lck_Blk
cd06622	73-267	PKc_PBS2_like
cd14217	10-321	STKc_SRPK2
cd05041	32-267	PTKc_Fes_like
cd05613	134-338	STKc_MSK1_N
cd05574	136-341	STKc_phototropin_like
cd05044	32-267	PTKc_c-ros
cd05101	30-218	PTKc_FGFR2
cd05090	52-247	PTKc_Ror1
cd05590	104-220	STKc_nPKC_eta
cd14112	24-214	STKc_Unc-89_rpt2
cd14149	6-279	STKc_C-Raf
cd05039	32-218	PTKc_Csk_like
cd14110	24-212	STKc_obscurin_rpt2
cd05051	52-242	PTKc_DDR
cd05098	30-218	PTKc_FGFR1
cd14000	65-219	STKc_LRRK
cd05065	32-267	PTKc_EphR_B
cd05618	23-265	STKc_aPKC_iota
cd05589	138-229	STKc_PKN
cd05113	29-218	PTKc_Btk_Bmx
cd05052	32-247	PTKc_Abl
cd14147	134-252	STKc_MLK3
cd05622	26-354	STKc_ROCK1
cd14151	14-279	STKc_B-Raf
cd05625	26-239	STKc_LATS1
cd05624	26-238	STKc_MRCK_beta
cd14144	75-218	STKc_BMPR1
cd05591	104-219	STKc_nPKC_epsilon
cd06640	123-218	STKc_MST4
cd05057	29-218	PTKc_EGFR_like
cd14054	32-228	STKc_BMPR2_AMHR2
cd05615	101-240	STKc_cPKC_alpha
cd14203	51-247	PTKc_Src_Fyn_like
cd13995	30-318	STKc_MAP3K8
cd05617	120-346	STKc_aPKC_zeta
cd14141	41-267	STKc_ACVR2a
cd05116	30-267	PTKc_Syk
cd14033	32-218	STKc_WNK4
cd06642	123-218	STKc_STK25
cd14102	73-261	STKc_PIM3
cd05082	29-218	PTKc_Csk
cd05056	73-174	PTKc_FAK
cd05114	29-218	PTKc_Tec_Rlk
cd14205	29-252	PTKc_Jak2_rpt2
cd14664	32-222	STK_BAK1_like
cd05091	52-247	PTKc_Ror2
cd14037	57-225	STKc_NAK_like
cd05071	52-266	PTKc_Src
cd05629	101-238	STKc_NDR_like_fungal
cd14108	9-214	STKc_SPEG_rpt1
cd13992	50-226	PK_GC
cd05079	23-255	PTKc_Jak1_rpt2
cd05588	120-219	STKc_aPKC
cd05081	52-231	PTKc_Jak3_rpt2
cd05627	97-219	STKc_NDR2
cd14053	48-199	STKc_ACVR2
cd13968	32-171	PKc_like
cd05628	26-219	STKc_NDR1
cd05606	126-338	STKc_beta_ARK
cd14027	66-173	STKc_RIP1
cd05046	26-253	PTK_CCK4
cd08216	52-212	PK_STRAD
cd05623	26-238	STKc_MRCK_alpha
cd05069	52-247	PTKc_Yes
cd05097	52-218	PTKc_DDR_like
cd05073	73-227	PTKc_Hck
cd14018	82-218	STKc_PINK1
cd13975	104-212	PKc_Dusty
cd05070	73-247	PTKc_Fyn
cd14042	52-219	PK_GC-A_B
cd05108	26-219	PTKc_EGFR
cd14063	29-243	PK_KSR
cd14067	121-219	STKc_LRRK1
cd05109	27-266	PTKc_HER2
cd14055	138-219	STKc_TGFbR2_like
cd05049	32-218	PTKc_Trk
cd14140	41-267	STKc_ACVR2b
cd13977	25-219	STKc_PDIK1L
cd05055	30-218	PTKc_PDGFR
cd14159	32-219	STKc_IRAK1
cd14220	73-218	STKc_BMPR1a
cd14223	128-219	STKc_GRK2
cd05075	30-237	PTKc_Axl
cd05054	30-218	PTKc_VEGFR
cd14130	25-174	STKc_TTBK1
cd05104	120-218	PTKc_Kit
cd05080	52-221	PTKc_Tyk2_rpt2
cd05040	14-267	PTKc_Ack_like
cd05633	123-219	STKc_GRK3
cd05058	32-174	PTKc_Met_Ron
cd14207	119-218	PTKc_VEGFR1
cd05105	133-227	PTKc_PDGFR_alpha
cd14143	123-197	STKc_TGFbR1_ACVR1b_ACVR1c
cd05092	32-218	PTKc_TrkA
cd14043	121-220	PK_GC-2D
cd05107	133-267	PTKc_PDGFR_beta
cd05047	32-219	PTKc_Tie
cd05103	133-218	PTKc_VEGFR2
cd14041	21-214	STKc_TLK2
cd14129	25-174	STKc_TTBK2
cd14031	32-218	STKc_WNK3
cd14012	76-220	PK_eIF2AK_GCN2_rpt1
cd05088	48-219	PTKc_Tie2
cd05597	101-218	STKc_DMPK_like
cd05115	51-267	PTKc_Zap-70
TIGR03724	142-174	arch_bud32
COG3642	142-175	Bud32
smart00220	26-321	S_TKc
pfam00069	26-321	Pkinase
PTZ00024	24-329	PTZ00024
PLN00009	23-322	PLN00009
COG0515	26-346	SPS1
PTZ00036	24-355	PTZ00036
smart00219	29-218	TyrKc
smart00221	29-218	STYKc
pfam07714	29-252	Pkinase_Tyr
PHA03210	2-319	PHA03210
PTZ00284	3-333	PTZ00284
PHA03209	26-319	PHA03209
PTZ00266	23-225	PTZ00266
PTZ00263	32-341	PTZ00263
PLN00034	32-212	PLN00034
PRK13184	23-228	pknD
PHA03212	13-327	PHA03212
PTZ00283	24-265	PTZ00283
PHA03211	123-319	PHA03211
TIGR03903	52-219	TOMM_kin_cyc
PTZ00267	131-295	PTZ00267
PHA03207	17-321	PHA03207
PHA03390	76-323	pk1
PTZ00426	29-252	PTZ00426
PLN03224	131-195	PLN03224
COG0478	106-170	RIO2
PLN03225	131-322	PLN03225

Ontology Information

   

HPRD ID	5460
Molecular Class	Serine/threonine kinase
Molecular Function	Auxiliary transport protein activity (GO:0015457)
Biological Process	Transport (GO:0006810)

SNP Information

View SNP Geneview Report