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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
MFAP3L 9848 microfibrillar-associated protein 3-like  4KIAA0626, NYD-sp9 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24735981   2014Cell line : SW480, SW620

Source : Beijing Cancer Hospital, Beijing, China.

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : -

Cell transfection, MTT, scratch wound healing and Transwell invasion assays,Cellular fractionation and western blotting,Immunofluorescence and confocal microscopy,ImmunohistochemistryUp-regulation-MFAP3L likely participates in the nuclear signaling of EGFR and ERK2 and acts as a novel nuclear kinase that impacts CRC metastasis.


Gene Details



NC_000004.11 (170907748..170948371, complement)

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Gene Type protein coding
Gene Family Immunoglobulin superfamily / I-set domain containing
Description -  
Chromosome 4
Location 4q33
Start 170907748  
End 170948371  
Strand -  
Gene Sequence

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Length 40624  
OMIM ID -   
HGNC ID HGNC:29083   
Unigene ID Hs.593942   
Ensembl ID ENSG00000198948   
PharmGKB ID PA134974574   

mRNA Information


mRNA ID ?NM_001009554.3
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS34103.1



Protein Information


      
Protein IDNP_001009554.1
Protein Namemicrofibrillar-associated protein 3-like
Molecular Wt. (Da)0
Protein Sequence

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Length 409  
Uniprot IDQ9UHK6
Ensembl Protein ID ENSP00000334424  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


No STRING Network could be found.

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0009664-139  Ig
cl1196064-139  Ig superfamily
pfam1389547-142  Ig_2
cd0573864-133  Ig2_RPTP_IIa_LAR_like
cd0585758-142  Ig2_FGFR
cd0496961-142  Ig5_Contactin_like
pfam1392747-129  Ig_3
cd0572961-142  Ig2_FGFR_like
cd0572568-142  Ig3_Robo
cd0573165-142  Ig3_L1-CAM_like
cd0572861-142  Ig4_Contactin-2-like
cd0574560-142  Ig3_Peroxidasin
pfam0004761-127  ig
cd0573664-142  Ig2_Follistatin_like
cd0585261-142  Ig5_Contactin-1
cd0589142-140  Ig_M-protein_C
cd0575074-142  Ig_Pro_neuregulin
cd0572461-133  Ig2_Robo
cd0496747-134  Ig1_Contactin
cd0573742-142  Ig_Myomesin_like_C
cd0584966-137  Ig1_Contactin-1
cd0572256-134  Ig1_Neogenin
cd0574666-140  Ig4_Peroxidasin
cd0576364-143  Ig_1
cd0497254-142  Ig_TrkABC_d4
cd0769347-143  Ig1_Robo
cd0576461-142  Ig_2
cd0496861-144  Ig3_Contactin_like
cd0573061-142  Ig3_NCAM-1_like
cd0585861-143  Ig3_FGFR-2
cd0497861-134  Ig4_L1-NrCAM_like
pfam0768655-142  V-set
cd0574361-134  Ig_Perlecan_D2_like
cd05754105-140  Ig3_Perlecan_like
smart0041055-142  IG_like
smart0040955-142  IG
pfam0767947-142  I-set
smart0040860-132  IGc2
PRK10811310-400  rne


Ontology Information


   
HPRD ID6572
Molecular ClassUnclassified
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO