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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
MUC17 140453 mucin 17, cell surface associated  7- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20702471   2010Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 106

Stage : -

Immunohistochemistry, immunoblotting, RT-PCRDown-regulation-MUC17 expression was decreased in hyperplastic polyps (p=0.0003), tubular and tubulovillous adenomas (p<0.0001) and colon cancers (p<0.0001).


Gene Details



NC_000007.13 (100663364..100702140)

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Gene Type protein coding
Gene Family Mucins
Description The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]  
Chromosome 7
Location 7q22
Start 100663364  
End 100702140  
Strand +  
Gene Sequence

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Length 38777  
OMIM ID 608424   
HGNC ID HGNC:16800   
Unigene ID Hs.271819   
Ensembl ID ENSG00000169876   
PharmGKB ID PA31315   

mRNA Information


mRNA ID ?NM_001040105.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS34711.1



Protein Information


      
Protein IDNP_001035194.1
Protein Namemucin 17, cell surface associated
Molecular Wt. (Da)0
Protein Sequence

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Length 4493  
Uniprot IDQ08AF3
Ensembl Protein ID ENSP00000299977  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam013904189-4275  SEA
cl025074189-4275  SEA superfamily
smart002004182-4288  SEA
PHA03247847-1417  PHA03247
PHA032472875-3361  PHA03247
PHA03247714-1240  PHA03247
PHA032471194-1770  PHA03247
PHA032471644-2241  PHA03247
PHA033071605-1979  PHA03307
PHA03307797-1222  PHA03307
PHA03307713-1046  PHA03307
PHA033071682-2048  PHA03307
PLN032093272-3484  PLN03209
PHA03307915-1265  PHA03307
PHA033071340-1716  PHA03307
PHA033072085-2473  PHA03307
PHA03247187-576  PHA03247
PHA033071350-1767  PHA03307
PRK149491712-2144  PRK14949
PHA032471970-2486  PHA03247
PHA032472187-2654  PHA03247
PRK108112408-2559  rne
COG38891720-1859  COG3889
PRK10811790-1048  rne
PHA033073212-3541  PHA03307
PHA032473318-3711  PHA03247
TIGR009271610-1931  2A1904
PHA033072819-3165  PHA03307
COG38893370-3517  COG3889
PRK108111372-1583  rne
PRK108112845-3068  rne
PRK149491123-1581  PRK14949
PRK127992416-2542  motB
PHA032473109-3617  PHA03247
PRK108112909-3111  rne
PRK108111100-1263  rne
pfam117252812-3049  AvrE
PHA033071113-1523  PHA03307
PHA032472677-3067  PHA03247
PRK11907943-1052  PRK11907
PRK079941626-1808  PRK07994
PRK149491412-1788  PRK14949
PRK079942401-2539  PRK07994
COG3889779-912  COG3889
PHA033072677-3120  PHA03307
COG56652705-2863  COG5665
PHA032471642-1982  PHA03247
COG38893017-3162  COG3889
TIGR009272081-2452  2A1904
PRK108112095-2344  rne
COG38891771-1911  COG3889
COG38892170-2271  COG3889
TIGR038351218-1525  termin_org_DnaJ
pfam117251692-1958  AvrE
PRK127991359-1482  motB
COG38892309-2448  COG3889
COG38892195-2336  COG3889
PRK11907923-1012  PRK11907
pfam051091582-1969  Herpes_BLLF1
COG38891625-1800  COG3889
PHA033071969-2356  PHA03307
PRK119072429-2543  PRK11907
pfam097262255-2466  Macoilin
PTZ004491193-1484  PTZ00449
PRK079941744-1853  PRK07994
TIGR009272741-3116  2A1904
PRK149492168-2553  PRK14949
PRK127993362-3485  motB
PRK108563325-3434  PRK10856
PLN022172957-3081  PLN02217
COG56652787-2982  COG5665
PHA03307200-535  PHA03307
PRK079941391-1500  PRK07994
COG38892211-2348  COG3889
TIGR009271536-1871  2A1904
PRK108111136-1343  rne
PRK108563364-3451  PRK10856
pfam117251339-1577  AvrE
PRK127993010-3132  motB
PHA033073176-3535  PHA03307
PLN031882410-2589  PLN03188
COG38892958-3093  COG3889
PRK119071761-1885  PRK11907
COG38891418-1561  COG3889
PRK108563441-3548  PRK10856
PRK127991123-1246  motB
COG38892898-3040  COG3889
COG3889899-1040  COG3889
COG3889800-983  COG3889
pfam051093113-3501  Herpes_BLLF1
PHA033072040-2409  PHA03307
COG3889906-1052  COG3889
PRK127992178-2306  motB
TIGR038352070-2339  termin_org_DnaJ
COG38892427-2572  COG3889
TIGR038351615-1901  termin_org_DnaJ
PHA03247430-1015  PHA03247
PRK12799946-1069  motB
PRK127993415-3544  motB
PRK119072859-2957  PRK11907
PHA033072361-2769  PHA03307
pfam051092779-3170  Herpes_BLLF1
COG54222159-2391  ROM1
TIGR038351255-1549  termin_org_DnaJ
PRK12799882-1010  motB
PRK11907420-511  PRK11907
PRK127991707-1835  motB
PRK108112762-2913  rne
PRK108112342-2507  rne
COG3889718-853  COG3889
PRK119071742-1834  PRK11907
PTZ00449787-1011  PTZ00449
pfam097261431-1577  Macoilin
COG38893834-3951  COG3889
PRK127992295-2424  motB
PRK119072717-2839  PRK11907
COG38891596-1749  COG3889
PTZ003951981-2264  PTZ00395
PTZ004492013-2265  PTZ00449
COG54221708-1977  ROM1
PRK10811398-576  rne
PRK108112809-2972  rne
TIGR03835320-656  termin_org_DnaJ
PRK127992474-2601  motB
COG38891367-1505  COG3889
PRK127992891-3014  motB


Ontology Information


   
HPRD ID6011
Molecular ClassIntegral membrane protein
Molecular FunctionTranscription regulator activity (GO:0030528)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO