Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| MUC5B | 727897 | mucin 5B, oligomeric mucus/gel-forming  | 11 | MG1  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21215095    | 2010 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 97 Stage : TNM Stage I-IV | Chip technology and immunohistochemistry | Unknown | - | The expression of PLAC1/CP1 genes correlates with various clinical and pathologic parameters. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Mucins |
| Description | This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]   | Chromosome | 11 |
| Location | 11p15.5 |
| Start | 1244295   |
| End | 1283406   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 39112   |
| OMIM ID | 600770    |
| HGNC ID | HGNC:7516    |
| Unigene ID | Hs.523395    |
| Ensembl ID | -    |
| PharmGKB ID | PA31321    |
mRNA Information
| mRNA ID | ?NM_002458.2 |
|---|---|
| Exon |   | mRNA Sequence |    Download   Select all |
| Length |   |
CDS Information
| Location | |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS44515.2 |    
Protein Information
| Protein ID | NP_002449.2 |
|---|---|
| Protein Name | mucin 5B, oligomeric mucus/gel-forming |
| Molecular Wt. (Da) | 0 |
| Protein Sequence |    Download   Select all |
| Length | 5762   |
| Uniprot ID | Q96JG8 |    
| Ensembl Protein ID | ENSP00000335385   |    
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Salivary secretion |    hsa04970 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00216 | 884-1041  | VWD |
| cl02516 | 884-1041  | VWD superfamily |
| smart00216 | 5064-5237  | VWD |
| cl02516 | 5064-5237  | VWD superfamily |
| pfam00094 | 895-1041  | VWD |
| smart00216 | 70-223  | VWD |
| cl02516 | 70-223  | VWD superfamily |
| pfam00094 | 5075-5238  | VWD |
| pfam00094 | 77-223  | VWD |
| smart00216 | 414-578  | VWD |
| cl02516 | 414-578  | VWD superfamily |
| pfam13330 | 1789-1878  | Mucin2_WxxW |
| cl16239 | 1789-1878  | Mucin2_WxxW superfamily |
| pfam13330 | 1340-1426  | Mucin2_WxxW |
| cl16239 | 1340-1426  | Mucin2_WxxW superfamily |
| pfam00094 | 425-579  | VWD |
| pfam13330 | 1508-1597  | Mucin2_WxxW |
| cl16239 | 1508-1597  | Mucin2_WxxW superfamily |
| pfam13330 | 4134-4222  | Mucin2_WxxW |
| cl16239 | 4134-4222  | Mucin2_WxxW superfamily |
| smart00832 | 615-685  | C8 |
| cl07383 | 615-685  | C8 superfamily |
| pfam13330 | 3577-3665  | Mucin2_WxxW |
| cl16239 | 3577-3665  | Mucin2_WxxW superfamily |
| pfam13330 | 2320-2408  | Mucin2_WxxW |
| cl16239 | 2320-2408  | Mucin2_WxxW superfamily |
| pfam13330 | 2877-2965  | Mucin2_WxxW |
| cl16239 | 2877-2965  | Mucin2_WxxW superfamily |
| pfam08742 | 615-685  | C8 |
| pfam08742 | 1078-1152  | C8 |
| cl07383 | 1078-1152  | C8 superfamily |
| smart00832 | 1078-1152  | C8 |
| smart00041 | 5660-5742  | CT |
| cl21545 | 5660-5742  | GHB_like superfamily |
| pfam08742 | 259-326  | C8 |
| cl07383 | 259-326  | C8 superfamily |
| pfam08742 | 5290-5351  | C8 |
| cl07383 | 5290-5351  | C8 superfamily |
| pfam01826 | 329-385  | TIL |
| cl20226 | 329-385  | TIL superfamily |
| smart00832 | 5291-5351  | C8 |
| smart00832 | 271-326  | C8 |
| pfam01826 | 794-855  | TIL |
| cl20226 | 794-855  | TIL superfamily |
| smart00214 | 5523-5586  | VWC |
| cl17735 | 5523-5586  | VWC superfamily |
| pfam00007 | 5676-5739  | Cys_knot |
| smart00215 | 387-432  | VWC_out |
| cl17735 | 387-432  | VWC superfamily |
| pfam01826 | 695-752  | TIL |
| cl20226 | 695-752  | TIL superfamily |
| pfam00093 | 5523-5586  | VWC |
| pfam05109 | 3295-3570  | Herpes_BLLF1 |
| PHA03255 | 3434-3564  | PHA03255 |
| pfam05109 | 3173-3562  | Herpes_BLLF1 |
| PRK13042 | 3470-3565  | PRK13042 |
| PHA03247 | 3295-3564  | PHA03247 |
| pfam05109 | 3160-3518  | Herpes_BLLF1 |
| PRK12799 | 3449-3566  | motB |
| COG3889 | 3444-3569  | COG3889 |
| PRK11907 | 3438-3552  | PRK11907 |
| PRK11907 | 3473-3574  | PRK11907 |
| PHA03247 | 2594-2864  | PHA03247 |
| pfam05109 | 2010-2313  | Herpes_BLLF1 |
| pfam05109 | 1954-2312  | Herpes_BLLF1 |
| pfam15402 | 3457-3562  | Spc7_N |
| PRK12495 | 3485-3565  | PRK12495 |
Ontology Information
| HPRD ID | 19369 |    
|---|---|
| Molecular Class | Adhesion molecule |
| Molecular Function | - |
| Biological Process | Cell growth and/or maintenance (GO:0008151)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
