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General Information
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 15979100 | 2005 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | DNA microarrays ,microarray, RT-PCR and luciferase assay | Up-regulation | - | MYCBP promoter, and that MYCBP up-regulation in colon carcinoma cell may play a co-activator role of c-MYC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011] | Chromosome | 1 |
| Location | 1p33-p32.2 |
| Start | 39328162 |
| End | 39339050 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 10889 |
| OMIM ID | 606535 |
| HGNC ID | HGNC:7554 |
| Unigene ID | Hs.591506 |
| Ensembl ID | ENSG00000214114 |
| PharmGKB ID | PA31354 |
Protein Information
| Protein ID | NP_036465.2 |
|---|---|
| Protein Name | MYC binding protein |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 103 |
| Uniprot ID | Q9NV56 |
| Ensembl Protein ID | ENSP00000359518 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 4609 | MYC | 1818 | NP_002458.2 | in vitro;in vivo;yeast 2-hybrid | 9797456 |
| 8165 | AKAP1 | 3905 | NP_003479.1 | in vitro;in vivo;yeast 2-hybrid | 1 241 480 711 483 600 |
| 8904 | CPNE1 | 5014 | NP_003906.2 | in vitro;yeast 2-hybrid | 12522145 |
| 55701 | - | 13335 | NP_060541.3 | yeast 2-hybrid | 16169070 |
| 57540 | PTCHD2 | 13852 | NP_065831.1 | yeast 2-hybrid | 16169070 |
| 131034 | CPNE4 | 5017 | NP_570720.1 | in vitro;yeast 2-hybrid | 12522145 |
| 221184 | CPNE2 | 5015 | NP_689940.3 | yeast 2-hybrid | 12522145 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
No matching records could be found.
Ontology Information
| HPRD ID | 5888 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Ubiquitin-specific protease activity (GO:0004843) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.