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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
MYCL 4610 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog  1LMYC, bHLHe38 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
15014029   2004Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 90

Stage : -

Genotyping and DNA sequencingMutation-CRC patients whose tumors exhibited LOH at MYCL1 at chromosome 1p34 were likely to have a poor prognosis.


Gene Details



NC_000001.10 (40361096..40367687, complement)

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Gene Type protein coding
Gene Family Basic helix-loop-helix proteins
Description -  
Chromosome 1
Location 1p34.3
Start 40361096  
End 40367687  
Strand -  
Gene Sequence

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Length 6592  
OMIM ID 164850   
HGNC ID HGNC:7555   
Unigene ID Hs.437922   
Ensembl ID ENSG00000116990   
PharmGKB ID PA31355   

mRNA Information


mRNA ID NM_001033082.2
Exon join(1..208,573..1077,4046..6592)  
mRNA Sequence

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Length 3260  



CDS Information


   
Location128..1312
CDS Sequence

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CCDS ID CCDS30682.1



Protein Information


      
Protein IDNP_001028254.2
Protein Namev-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
Molecular Wt. (Da)35313
Protein Sequence

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Length 394  
Uniprot IDP04818
Ensembl Protein ID ENSP00000314727  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation299
SPhosphorylation299

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
4149MAX1113NP_002373.3in vitro10229200   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd00083279-333  HLH
cl00081279-333  HLH superfamily
pfam010562-220  Myc_N
cl030822-220  Myc_N superfamily
pfam00010282-333  HLH
smart00353287-333  HLH
PRK0776418-167  PRK07764
PRK1280095-194  fliF


Ontology Information


   
HPRD ID2814
Molecular ClassNot Available
Molecular FunctionTranscription factor activity (GO:0003700)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO