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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| NAP1L1 | 4673 | nucleosome assembly protein 1-like 1 | 12 | NRP, NAP1, NAP1L, MGC8688, MGC23410 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 12384809 | 2002 | Cell line : - Source : Latvian oncology Center Sample Type : CRC tumor and normal tissue No. of Sample : 22 Stage : - | Immunoscreening, serological identification of antigens by recombinant expression cloning | Up-regulation | - | Serological responses to three antigens (C21ORF2, EPRS and NAP1L1) were found mainly in cancer patients' sera. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms; however, not all have been fully described. [provided by RefSeq, Apr 2015] | Chromosome | 12 |
| Location | 12q21.1 |
| Start | 76438672 |
| End | 76478738 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 40067 |
| OMIM ID | 164060 |
| HGNC ID | HGNC:7637 |
| Unigene ID | Hs.524599 |
| Ensembl ID | ENSG00000187109 |
| PharmGKB ID | PA31439 |
mRNA Information
| mRNA ID | NM_139207.3 |
|---|---|
| Exon | join(1..392,10720..10756,15965..16050,17486..17588, 24680..24821,25081..25161,28798..28926,29869..29940, 31050..31189,31609..31754,31849..31868,34306..34428, 35174..35203,35709..35759,36495..36566,37241..40067) | mRNA Sequence | Download Select all |
| Length | 4040 |
Protein Information
| Protein ID | NP_631946.1 |
|---|---|
| Protein Name | nucleosome assembly protein 1-like 1 |
| Molecular Wt. (Da) | 9018 |
| Protein Sequence | Download Select all |
| Length | 391 |
| Uniprot ID | P55851 |
| Ensembl Protein ID | ENSP00000312029 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| C | Farnesylation | 388 |
| T | Phosphorylation | 62 |
| C | Farnesylation | 388 |
| T | Phosphorylation | 62 |
| S | Phosphorylation | 10 |
| S | Phosphorylation | 10 |
| T | Phosphorylation | 64 |
| T | Phosphorylation | 64 |
| Y | Phosphorylation | 66 |
| Y | Phosphorylation | 66 |
| S | Phosphorylation | 69 |
| S | Phosphorylation | 69 |
| S | Phosphorylation | 143 |
| S | Phosphorylation | 143 |
| K | Acetylation | 116 |
| K | Acetylation | 116 |
| K | Acetylation | 194 |
| K | Acetylation | 194 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1387 | CREBBP | 2534 | NP_004371.2 | in vitro | 11940655 |
| 2033 | EP300 | 4078 | NP_001420.2 | in vitro;in vivo;yeast 2-hybrid | 11940655 |
| 7157 | TP53 | 1859 | NP_000537.3 | in vitro | 14966293 |
| 79187 | FSD1 | 17021 | NP_077309.1 | yeast 2-hybrid | 16169070 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00956 | 75-343 | NAP |
| cl08298 | 75-343 | NAP superfamily |
| PTZ00007 | 50-343 | PTZ00007 |
| PTZ00008 | 83-267 | PTZ00008 |
Ontology Information
| HPRD ID | 2508 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Transferase activity (GO:0016740) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091) |
Drug Information
No matching records could be found.