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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
NAT10 55226 N-acetyltransferase 10 (GCN5-related)  11hALP, FLJ10774, FLJ12179, NET43, KIAA1709 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24982245   2014Cell line : -

Source : -

Sample Type : Population based case control study

No. of Sample : 222

Stage : -

Immunohistochemistry,immunofluorescence, Western blotting, and Transwell assaysSubcellular redistribution- NAT10 may be a useful prognostic marker and potential therapeutic target in colorectal carcinoma.


Gene Details



NC_000011.9 (34127111..34172581)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 11
Location 11p13
Start 34127111  
End 34172581  
Strand +  
Gene Sequence

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Length 45471  
OMIM ID 609221   
HGNC ID HGNC:29830   
Unigene ID Hs.577281   
Ensembl ID ENSG00000135372   
PharmGKB ID PA143485555   

mRNA Information


mRNA ID ?NM_001144030.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS44568.1



Protein Information


      
Protein IDNP_001137502.1
Protein NameN-acetyltransferase 10 (GCN5-related)
Molecular Wt. (Da)0
Protein Sequence

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Length 1025  
Uniprot IDQ6YHU6
Ensembl Protein ID ENSP00000385441  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation934
SPhosphorylation984
SPhosphorylation987
SPhosphorylation990
SPhosphorylation435
TPhosphorylation932
KAcetylation426
SPhosphorylation589
TPhosphorylation443
TPhosphorylation450
SPhosphorylation809
SPhosphorylation190

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
Ribosome biogenesis in eukaryotes hsa03008


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd04301616-648  NAT_SF
cl17182616-648  NAT_SF superfamily
pfam13718528-753  GNAT_acetyltr_2
pfam05127302-480  Helicase_RecD
cl21455302-480  P-loop_NTPase superfamily
pfam08351107-201  DUF1726
cl07096107-201  DUF1726 superfamily
pfam13725771-892  tRNA_bind_2
cl16364771-892  tRNA_bind_2 superfamily
pfam00583616-655  Acetyltransf_1
pfam13508623-659  Acetyltransf_7
COG144420-901  TmcA
TIGR01575624-655  rimI
PLN03229900-997  PLN03229
COG0456612-682  RimI


Ontology Information


   
HPRD ID7090
Molecular ClassEnzyme: Acyltransferase
Molecular FunctionMetallopeptidase activity (GO:0008237)
Biological ProcessProteolysis and peptidolysis (GO:0006508); Inflammatory response (GO:0006954)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO